Published in Biochemistry on March 27, 1973
Interaction of penicillin with the bacterial cell: penicillin-binding proteins and penicillin-sensitive enzymes. Bacteriol Rev (1974) 7.49
Molecular weight, amino acid composition and physicochemical properties of the exocellular DD-carboxypeptidase-transpeptidase of Streptomyces R39. Biochem J (1974) 1.91
Kinetics of concomitant transfer and hydrolysis reactions catalysed by the exocellular DD-carboxypeptidase-transpeptidase of streptomyces R61. Biochem J (1973) 1.86
Binding of beta-lactam antibiotics to the exocellular DD-carboxypeptidase-transpeptidase of Streptomyces R39. Biochem J (1974) 1.30
Enzymic mechanisms involving concomitant transfer and hydrolysis reactions. Biochem J (1973) 1.28
Activities and regulation of peptidoglycan synthases. Philos Trans R Soc Lond B Biol Sci (2015) 1.05
Cloning and amplified expression in Streptomyces lividans of the gene encoding the extracellular beta-lactamase of Actinomadura R39. Biochem J (1989) 0.94
On the substrate specificity of bacterial DD-peptidases: evidence from two series of peptidoglycan-mimetic peptides. Biochem J (2003) 0.91
Crystal structures of complexes of bacterial DD-peptidases with peptidoglycan-mimetic ligands: the substrate specificity puzzle. J Mol Biol (2008) 0.90
Biosynthesis of peptidoglycan in Gaffkya homari: on the target(s) of benzylpenicillin. Antimicrob Agents Chemother (1991) 0.90
Site-directed mutagenesis of the Actinomadura R39 DD-peptidase. Biochem J (1997) 0.81
Specificity and reversibility of the transpeptidation reaction catalyzed by the Streptomyces R61 D-Ala-D-Ala peptidase. Protein Sci (2005) 0.77
Neisseria gonorrhoeae penicillin-binding protein 3 demonstrates a pronounced preference for N(epsilon)-acylated substrates. Biochemistry (2009) 0.75
The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine. Intensive Care Med (1996) 35.00
A standard numbering scheme for the class A beta-lactamases. Biochem J (1991) 17.44
Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units: results of a multicenter, prospective study. Working group on "sepsis-related problems" of the European Society of Intensive Care Medicine. Crit Care Med (1998) 13.94
Sequence identification of 2,375 human brain genes. Nature (1992) 9.53
Use of bacteriolytic enzymes in determination of wall structure and their role in cell metabolism. Bacteriol Rev (1968) 8.95
Neuropathic pain: redefinition and a grading system for clinical and research purposes. Neurology (2007) 8.08
The active-site-serine penicillin-recognizing enzymes as members of the Streptomyces R61 DD-peptidase family. Biochem J (1988) 7.51
Mechanisms of enzymatic bacteriaolysis. Cell walls of bacteri are solubilized by action of either specific carbohydrases or specific peptidases. Science (1967) 5.14
Comparison of the sequences of class A beta-lactamases and of the secondary structure elements of penicillin-recognizing proteins. Antimicrob Agents Chemother (1991) 5.05
Acute renal failure in the ICU: risk factors and outcome evaluated by the SOFA score. Intensive Care Med (2000) 4.74
Multimodular penicillin-binding proteins: an enigmatic family of orthologs and paralogs. Microbiol Mol Biol Rev (1998) 4.70
The 3-D structure of a zinc metallo-beta-lactamase from Bacillus cereus reveals a new type of protein fold. EMBO J (1995) 4.30
Modifications of the acyl-D-alanyl-D-alanine terminus affecting complex-formation with vancomycin. Biochem J (1971) 3.98
Sensitivity to ampicillin and cephalothin of enzymes involved in wall peptide crosslinking in Escherichia coli K12, strain 44. Eur J Biochem (1974) 3.43
Specificity of combination between mucopeptide precursors and vancomycin or ristocetin. Biochem J (1969) 3.38
Cloning and nucleotide sequencing of the gene encoding the beta-lactamase from Citrobacter diversus. FEMS Microbiol Lett (1991) 3.24
Nucleotide sequence of the gene encoding the Streptomyces albus G beta-lactamase precursor. Eur J Biochem (1987) 3.06
Penicillin-sensitive DD-carboxypeptidase from Streptomyces strain R 61. Biochemistry (1971) 2.92
On the origin of bacterial resistance to penicillin: comparison of a beta-lactamase and a penicillin target. Science (1986) 2.88
Peripheral and central mechanisms of cutaneous hyperalgesia. Prog Neurobiol (1992) 2.80
The crystal structure of the beta-lactamase of Streptomyces albus G at 0.3 nm resolution. Biochem J (1987) 2.59
Penicillin-sensitive DD-carboxypeptidases from Streptomyces strains R39 and K11. Biochemistry (1972) 2.54
Nucleotide sequences of the pbpX genes encoding the penicillin-binding proteins 2x from Streptococcus pneumoniae R6 and a cefotaxime-resistant mutant, C506. Mol Microbiol (1989) 2.50
Topical application of clonidine relieves hyperalgesia in patients with sympathetically maintained pain. Pain (1991) 2.42
Mechanism of acyl transfer by the class A serine beta-lactamase of Streptomyces albus G. Biochem J (1991) 2.39
Modular design of the Enterococcus hirae muramidase-2 and Streptococcus faecalis autolysin. FEMS Microbiol Lett (1992) 2.33
Transpeptidase activity of Streptomyces D-alanyl-D carboxypeptidases. Proc Natl Acad Sci U S A (1972) 2.30
Nucleotide sequence of the gene encoding the active-site serine beta-lactamase from Actinomadura R39. FEMS Microbiol Lett (1989) 2.29
Fluorescence and circular dichroism studies on the Streptomyces R61 DD-carboxypeptidase-transpeptidase. Penicillin binding by the enzyme. Biochem J (1973) 2.15
Exocellular DD-carboxypeptidases-transpeptidases from Streptomyces. Methods Enzymol (1976) 2.13
Solubilization and isolation of the membrane-bound DD-carboxypeptidase of Streptococcus faecalis ATCC9790. Properties of the purified enzyme. Eur J Biochem (1978) 2.10
The penicillin-binding proteins in Streptococcus faecalis ATCC 9790. Eur J Biochem (1980) 2.07
Fractionation of the DD-carboxypeptidase-transpeptidase activities solubilized from membranes of Escherichia coli K12, strain 44. Eur J Biochem (1974) 2.06
Nutritional factors controlling exocellular protease production by Pseudomonas aeruginosa. J Bacteriol (1980) 2.06
Isolation of DD carboxypeptidase from Streptomyces albus G culture filtrates. Biochemistry (1970) 2.04
Substrate requirements of the Streptomyces albus G DD carboxypeptidase. Biochemistry (1970) 2.01
The wall peptidoglycans of Neisseria perflava, Moraxella glucidolytica, Pseudomonas alcaligenes and Proteus vulgaris strain P18. Eur J Biochem (1973) 1.99
Structure of the cell wall of Staphylococcus aureus, strain Copenhagen. IX. Teichoic acid and phage adsorption. Biochemistry (1968) 1.99
Evidence for two different heat transduction mechanisms in nociceptive primary afferents innervating monkey skin. J Physiol (1995) 1.97
The cell wall peptidoglycan of Bacillus megaterium KM. I. Studies on the stereochemistry of alpha, alpha'-diaminopimelic acid. Biochemistry (1967) 1.96
Compounds formed between nucleotides related to the biosynthesis of bacterial cell wall and vancomycin. Biochem Biophys Res Commun (1966) 1.96
The preparation of iodinated vancomycin and its distribution in bacteria treated with the antibiotic. Biochem J (1970) 1.92
CD43 interacts with moesin and ezrin and regulates its redistribution to the uropods of T lymphocytes at the cell-cell contacts. Blood (1998) 1.91
Molecular weight and amino acid composition of the exocellular DD-carboxypeptidase-transpeptidase of Streptomyces R61. Biochem J (1973) 1.91
Molecular weight, amino acid composition and physicochemical properties of the exocellular DD-carboxypeptidase-transpeptidase of Streptomyces R39. Biochem J (1974) 1.91
Comparison of responses of warm and nociceptive C-fiber afferents in monkey with human judgments of thermal pain. J Neurophysiol (1978) 1.90
Streptomyces DD-carboxypeptidases as transpeptidases. The specificity for amino compounds acting as carboxyl acceptors. Biochem J (1973) 1.87
The direction of glycan synthesis in a bacterial peptidoglycan. Biochem J (1973) 1.87
Transcription and expression analysis, using lacZ and phoA gene fusions, of Mycobacterium fortuitum beta-lactamase genes cloned from a natural isolate and a high-level beta-lactamase producer. Mol Microbiol (1994) 1.86
Kinetics of concomitant transfer and hydrolysis reactions catalysed by the exocellular DD-carboxypeptidase-transpeptidase of streptomyces R61. Biochem J (1973) 1.86
A putative, ubiquitin-dependent mechanism for the recognition and elimination of defective spermatozoa in the mammalian epididymis. J Cell Sci (2001) 1.86
The catalytic, glycosyl transferase and acyl transferase modules of the cell wall peptidoglycan-polymerizing penicillin-binding protein 1b of Escherichia coli. Mol Microbiol (1999) 1.85
Physicochemical properties of vancomycin and iodovancomycin and their complexes with diacetyl-L-lysyl-D-alanyl-D-alanine. Biochem J (1971) 1.85
Overexpression, solubilization and refolding of a genetically engineered derivative of the penicillin-binding protein 3 of Escherichia coli K12. Mol Microbiol (1988) 1.84
Peptide cross-links in bacterial cell wall peptidoglycans studied with specific endopeptidases from Streptomyces albus G. Biochemistry (1966) 1.80
Occurrence of D-alanyl-(D)-meso-diaminopimelic acid and meso-diaminopimelyl-meso-diaminopimelic acid interpeptide linkages in the peptidoglycan of Mycobacteria. Biochemistry (1974) 1.79
Primary structure of the Streptomyces R61 extracellular DD-peptidase. 1. Cloning into Streptomyces lividans and nucleotide sequence of the gene. Eur J Biochem (1987) 1.77
Chemokines regulate cellular polarization and adhesion receptor redistribution during lymphocyte interaction with endothelium and extracellular matrix. Involvement of cAMP signaling pathway. J Cell Biol (1995) 1.76