Published in J Cell Biol on August 01, 1973
How neutrophils kill microbes. Annu Rev Immunol (2005) 6.87
Antibacterial activity of cationic proteins from human granulocytes. J Clin Invest (1975) 2.97
Damage to pseudohyphal forms of Candida albicans by neutrophils in the absence of serum in vitro. J Clin Invest (1978) 2.72
A specific collagenase from rabbit fibroblasts in monolayer culture. Biochem J (1974) 2.53
Chemiluminescence of phagocytic cells caused by N-formylmethionyl peptides. J Exp Med (1978) 2.45
Stimulation by endocytosis of the secretion of collagenase and neutral proteinase from rabbit synovial fibroblasts. J Exp Med (1974) 2.36
Selective labilization of specific granules in polymorphonuclear leukocytes by phorbol myristate acetate. Am J Pathol (1974) 2.27
Release of gelatinase from a novel secretory compartment of human neutrophils. J Clin Invest (1982) 2.21
The role of lactoferrin in the bactericidal function of polymorphonuclear leucocytes. Immunology (1979) 2.20
Kinetics of fusion of the cytoplasmic granules with phagocytic vacuoles in human polymorphonuclear leukocytes. Biochemical and morphological studies. J Cell Biol (1980) 1.87
Early and discrete changes in permeability of Escherichia coli and certain other gram-negative bacteria during killing by granulocytes. J Exp Med (1974) 1.82
Intracellular and extracellular degranulation of human polymorphonuclear azurophil and specific granules induced by immune complexes. Infect Immun (1974) 1.73
The differential mobilization of human neutrophil granules. Effects of phorbol myristate acetate and ionophore A23187. Am J Pathol (1977) 1.60
Interaction of the two components of leukocidin from Staphylococcus aureus with human polymorphonuclear leukocyte membranes: sequential binding and subsequent activation. Infect Immun (1994) 1.56
Collagenase is a component of the specific granules of human neutrophil leucocytes. Biochem J (1977) 1.55
T lymphocyte recruitment by interleukin-8 (IL-8). IL-8-induced degranulation of neutrophils releases potent chemoattractants for human T lymphocytes both in vitro and in vivo. J Clin Invest (1996) 1.53
Lysis and killing of bacteria by lysosomal proteinases. Infect Immun (1976) 1.50
Acidification of phagosomes is initiated before lysosomal enzyme activity is detected. J Cell Biol (1983) 1.48
The polymorphonuclear leukocyte. Agents Actions (1978) 1.43
Phagocytosing human neutrophils inactivate their own granular enzymes. J Clin Invest (1981) 1.42
Fate of human lactoferrin and myeloperoxidase in phagocytizing human neutrophils: effects of immunoglobulin G subclasses and immune complexes coated on latex beads. Infect Immun (1975) 1.42
Differential control of azurophilic and specific granule exocytosis in Sendai-virus-permeabilized rabbit neutrophils. J Physiol (1987) 1.37
Inflammatory mediators in dengue virus infection in children: interleukin-8 and its relationship to neutrophil degranulation. Infect Immun (2000) 1.30
Cytotoxicity for tumor cells of cationic proteins from human neutrophil granules. J Cell Biol (1976) 1.18
The opsonizing ligand on Salmonella typhimurium influences incorporation of specific, but not azurophil, granule constituents into neutrophil phagosomes. J Cell Biol (1989) 1.16
Bacterial phospholipid hydrolysis enhances the destruction of Escherichia coli ingested by rabbit neutrophils. Role of cellular and extracellular phospholipases. J Clin Invest (1990) 1.16
Preferential inhibition of primary granule release from bovine neutrophils by a Brucella abortus extract. Infect Immun (1986) 1.12
Internalization of Shigella flexneri into HeLa cells occurs without an increase in cytosolic Ca2+ concentration. Infect Immun (1989) 1.10
Role of hydrogen peroxide and peroxidase in the cytotoxicity of Trypanosoma dionisii by human granulocytes. Infect Immun (1978) 1.04
Cytochemical demonstration of hydrogen peroxide in polymorphonuclear leukocyte phagosomes. J Cell Biol (1975) 1.03
Administration of C1 inhibitor reduces neutrophil activation in patients with sepsis. Clin Diagn Lab Immunol (2003) 1.00
Experimental Pseudomonas keratitis. Trans Am Ophthalmol Soc (1981) 1.00
Myeloperoxidase-mediated platelet release reaction. J Clin Invest (1979) 0.98
Neutrophilic granulocytes in acute bacterial infection. Sequential studies on lysozyme, myeloperoxidase and lactoferrin. Clin Exp Immunol (1976) 0.97
Proteinase 3-dependent caspase-3 cleavage modulates neutrophil death and inflammation. J Clin Invest (2014) 0.95
Elastase-like enzymes in human neutrophils localized by ultrastructural cytochemistry. J Cell Biol (1980) 0.94
Bactericidal capacity of phorbol myristate acetate-treated human polymorphonuclear leukocytes. Infect Immun (1978) 0.92
Colocalization of elastase and myeloperoxidase in human blood and bone marrow neutrophils using a monoclonal antibody and immunogold. Am J Pathol (1989) 0.91
Linkage of azurophil granule secretion in neutrophils to chloride ion transport and endosomal transcytosis. J Clin Invest (1994) 0.89
A possible role for lysozyme in determining acute exacerbation in chronic bronchitis. Clin Exp Immunol (1995) 0.88
Analytical subcellular fractionation of alveolar macrophages from normal and BCG-vaccinated rabbits with particular reference to heterogeneity of hydrolase-containing granules. Biochem J (1979) 0.88
Interstitial porphyrins and tubule degeneration in the hamster Harderian gland. J Anat (1985) 0.86
Neutrophil expression of tumour necrosis factor receptors (TNF-R) and of activation markers (CD11b, CD43, CD63) in rheumatoid arthritis. Clin Exp Immunol (1995) 0.86
Lysosomal enzyme cytochemistry of blood neutrophils. J Clin Pathol (1978) 0.84
Effect of phorbol myristate acetate on cellular metabolism and lysozyme release from alveolar macrophages and polymorphonuclear leukocytes. Infect Immun (1978) 0.84
Appearance of Fc receptors on polymorphonuclear leukocytes after migration and their role in phagocytosis. Infect Immun (1986) 0.84
Characterization of monkey peripheral neutrophil granules during infection. Infect Immun (1975) 0.82
Alkaline phosphatase as a marker of maturity in human neutrophils. Studies in normals dosed with aetiocholanolone and prednisolone. J Clin Pathol (1980) 0.82
Internalization of type 1 complement receptors and de novo multivesicular body formation during chemoattractant-induced endocytosis in human neutrophils. J Clin Invest (1994) 0.81
Neutrophil-mediated killing of Dipetalonema viteae microfilariae: simultaneous presence of IgE, IgG antibodies and complement is required. Immunology (1984) 0.77
Lime Juice and Vinegar Injections as a Cheap and Natural Alternative to Control COTS Outbreaks. PLoS One (2015) 0.77
pH-dependent penicillin tolerance may protect intraleukocytic Staphylococcus aureus from killing by cloxacillin. Antimicrob Agents Chemother (1982) 0.77
Inhibition of human neutrophil oxidative metabolism and degranulation in vitro by nitroblue tetrazolium and vitamin E. Am J Pathol (1978) 0.76
A review of the proposed role of neutrophils in rodent amebic liver abscess models. Parasite (2016) 0.75
The early stages of absorption of injected horseradish peroxidase in the proximal tubules of mouse kidney: ultrastructural cytochemistry by a new technique. J Histochem Cytochem (1966) 46.81
The isolation and properties of the specific cytoplasmic granules of rabbit polymorphonuclear leucocytes. J Exp Med (1960) 21.07
Functions of lysosomes. Annu Rev Physiol (1966) 17.76
Degranulation of polymorphonuclear leucocytes following phagocytosis of microorganisms. J Exp Med (1960) 10.03
Functional and metabolic properties of polymorphonuclear leucocytes. I. Observations on the requirements and consequences of particle ingestion. J Exp Med (1960) 9.05
ELECTRON MICROSCOPE STUDIES ON THE DEGRANULATION OF RABBIT PERITONEAL LEUKOCYTES DURING PHAGOCYTOSIS. J Exp Med (1964) 6.12
Origin of granules in polymorphonuclear leukocytes. Two types derived from opposite faces of the Golgi complex in developing granulocytes. J Cell Biol (1966) 5.96
The fate of bacteria within phagocytic cells. I. The degradation of isotopically labeled bacteria by polymorphonuclear leucocytes and macrophages. J Exp Med (1963) 5.96
Cinemicrophotographic observations on granule lysis in polymorphonuclear leucocytes during phagocytosis. J Exp Med (1962) 5.42
The influence of phagocytosis on the intracellular distribution of granule-associated components of polymorphonuclear leucocytes. J Exp Med (1960) 5.27
Differences in enzyme content of azurophil and specific granules of polymorphonuclear leukocytes. II. Cytochemistry and electron microscopy of bone marrow cells. J Cell Biol (1968) 5.20
Resolution of granules from rabbit heterophil leukocytes into distinct populations by zonal sedimentation. J Cell Biol (1969) 4.36
The dissociation by colchicine of phagocytosis from increased oxygen consumption in human leukocytes. J Clin Invest (1967) 4.22
Effect of cyclic AMP on release of lysosomal enzymes from phagocytes. Nat New Biol (1971) 4.09
The metabolism of leukocytes. Semin Hematol (1968) 3.55
Isolation and properties of phagocytic vesicles from polymorphonuclear leukocytes. J Clin Invest (1971) 3.39
Temporal changes in pH within the phagocytic vacuole of the polymorphonuclear neutrophilic leukocyte. J Cell Biol (1973) 3.34
Association of lactoferrin with specific granules in rabbit heterophil leukocytes. J Exp Med (1970) 3.32
Fine structural localization of acid and alkaline phosphatases in cells of rabbit blood and bone marrow. J Histochem Cytochem (1967) 3.31
Differences in enzyme content of azurophil and specific granules of polymorphonuclear leukocytes. I. Histochemical staining of bone marrow smears. J Cell Biol (1968) 3.13
Fine structural studies on the development of heterophil, eosinophil, and basophil granulocytes in rabbits. Lab Invest (1967) 3.10
Further biochemical and morphological studies of granule fractions from rabbit heterophil leukocytes. J Cell Biol (1970) 3.06
Quantitative studies of phagocytosis by polymorphonuclear leukocytes: use of emulsions to measure the initial rate of phagocytosis. J Clin Invest (1972) 2.88
The immunologic release of constituents from neutrophil leukocytes. II. Mechanisms of release during phagocytosis, and adherence to nonphagocytosable surfaces. J Immunol (1971) 2.85
Cytochemical localization of certain phosphatases in Escherichia coli. J Bacteriol (1970) 2.43
Intraleukocytic microbicidal defects. Annu Rev Med (1971) 2.14
A PERMEABILITY FACTOR RELEASED FROM LEUKOCYTES AFTER PHAGOCYTOSIS OF IMMUNE COMPLEXES AND ITS POSSIBLE ROLE IN THE ARTHUS REACTION. Life Sci (1964) 2.12
The mobilization and extracellular release of granular enzymes from human leukocytes during phagocytosis. J Cell Biol (1972) 1.84
PHAGOCYTOSIS OF BACTERIA BY HETEROPHIL LEUKOCYTES: ACID AND ALKALINE PHOSPHATASE CYTOCHEMISTRY. Am J Pathol (1964) 1.76
Cytochemical localization of acid phosphatase activity in granule fractions from rabbit polymorphonuclear leukocytes. J Cell Biol (1972) 1.74
Neutrophil proteases in inflammation. Annu Rev Med (1972) 1.63
Studies on isolated membranes of azurophil and specific granules from rabbit polymorphonuclear leukocytes. J Cell Biol (1972) 1.09
Formation and localization of the alkaline phosphatase of Escherichia coli. Ann N Y Acad Sci (1969) 1.09
The appearance of lecithin- 32 P, synthesized from lysolecithin- 32 P, in phagosomes of polymorphonuclear leukocytes. J Clin Invest (1972) 0.86
The effect of the morphine analog levorphanol on phagocytosing leukocytes. A morphologic study. Lab Invest (1971) 0.85
Defensins. Natural peptide antibiotics of human neutrophils. J Clin Invest (1985) 8.63
Origin of granules in polymorphonuclear leukocytes. Two types derived from opposite faces of the Golgi complex in developing granulocytes. J Cell Biol (1966) 5.96
Differences in enzyme content of azurophil and specific granules of polymorphonuclear leukocytes. II. Cytochemistry and electron microscopy of bone marrow cells. J Cell Biol (1968) 5.20
The development of neutrophilic polymorphonuclear leukocytes in human bone marrow. J Exp Med (1971) 4.98
GMP-140, a platelet alpha-granule membrane protein, is also synthesized by vascular endothelial cells and is localized in Weibel-Palade bodies. J Clin Invest (1989) 4.59
P-selectin glycoprotein ligand-1 mediates rolling of human neutrophils on P-selectin. J Cell Biol (1995) 4.31
Stimulated mobilization of monocyte Mac-1 and p150,95 adhesion proteins from an intracellular vesicular compartment to the cell surface. J Clin Invest (1987) 3.40
Temporal changes in pH within the phagocytic vacuole of the polymorphonuclear neutrophilic leukocyte. J Cell Biol (1973) 3.34
Differences in enzyme content of azurophil and specific granules of polymorphonuclear leukocytes. I. Histochemical staining of bone marrow smears. J Cell Biol (1968) 3.13
A platelet alpha-granule membrane protein (GMP-140) is expressed on the plasma membrane after activation. J Cell Biol (1985) 3.02
Segregation and packaging of granule enzymes in eosinophilic leukocytes. J Cell Biol (1970) 2.94
Differentiation of monocytes. Origin, nature, and fate of their azurophil granules. J Cell Biol (1971) 2.86
The human antibacterial cathelicidin, hCAP-18, is synthesized in myelocytes and metamyelocytes and localized to specific granules in neutrophils. Blood (1997) 2.16
Identification of neutrophil gelatinase-associated lipocalin as a novel matrix protein of specific granules in human neutrophils. Blood (1994) 2.14
Retraction. Am J Respir Crit Care Med (2000) 2.14
Transepithelial transport of a viral membrane glycoprotein implanted into the apical plasma membrane of Madin-Darby canine kidney cells. I. Morphological evidence. J Cell Biol (1983) 2.07
Redistribution of alpha-granules and their contents in thrombin-stimulated platelets. J Cell Biol (1984) 2.06
Quantitation of L-selectin distribution on human leukocyte microvilli by immunogold labeling and electron microscopy. J Histochem Cytochem (1996) 1.97
Purification and characterization of human lysosomal membrane glycoproteins. Arch Biochem Biophys (1989) 1.90
Changes in pH within the phagocytic vacuoles of human neutrophils and monocytes. Lab Invest (1978) 1.88
The location of proteins labeled by the 125I-lactoperoxidase system in the NIL 8 hamster fibroblast. Cell (1975) 1.84
Appearance of peroxidase reactivity within the rough endoplasmic reticulum of blood monocytes after surface adherence. J Exp Med (1977) 1.81
Cytochemical localization of acid phosphatase activity in granule fractions from rabbit polymorphonuclear leukocytes. J Cell Biol (1972) 1.74
Changing patterns of plasma membrane-associated filaments during the initial phases of polymorphonuclear leukocyte adherence. J Cell Biol (1979) 1.67
Activated neutrophils express proteinase 3 on their plasma membrane in vitro and in vivo. Clin Exp Immunol (1994) 1.61
Differentiation of human monocytes in bone marrow and blood. Sequential formation of two granule populations. Lab Invest (1973) 1.60
Association of alkaline-phosphatase-positive reticulum cells in bone marrow with granulocytic precursors. J Exp Med (1979) 1.58
Ultrastructural localization of proteinase 3, the target antigen of anti-cytoplasmic antibodies circulating in Wegener's granulomatosis. Am J Pathol (1990) 1.57
Human neutrophil granules and secretory vesicles. Eur J Haematol (1993) 1.56
Neutrophil tethering to and rolling on E-selectin are separable by requirement for L-selectin. Immunity (1994) 1.51
Cytoplasmic domain of P-selectin (CD62) contains the signal for sorting into the regulated secretory pathway. Mol Biol Cell (1992) 1.48
The platelet fibrinogen receptor: an immunogold-surface replica study of agonist-induced ligand binding and receptor clustering. J Cell Biol (1987) 1.47
Enzyme histochemistry and immunohistochemistry on biopsy specimens of pathologic human bone marrow. Blood (1981) 1.47
Changes in subcellular localization and surface expression of L-selectin, alkaline phosphatase, and Mac-1 in human neutrophils during stimulation with inflammatory mediators. J Leukoc Biol (1994) 1.44
Ultrastructural localization of a macrophage-restricted sialic acid binding hemagglutinin, SER, in macrophage-hematopoietic cell clusters. Blood (1990) 1.34
Cytochemical localization of lysosomal enzymes in rat megakaryocytes and platelets. J Clin Invest (1975) 1.31
Leukocyte activation induces surface redistribution of P-selectin glycoprotein ligand-1. J Leukoc Biol (1997) 1.30
Identification of alpha-naphthyl butyrate esterase as a plasma membrane ectoenzyme of monocytes and as a discrete intracellular membrane-bounded organelle in lymphocytes. J Exp Med (1981) 1.28
Changes in plasma-membrane-associated filaments during endocytosis and exocytosis in polymorphonuclear leukocytes. Cell (1981) 1.26
Formation and structure of specific granules in basophilic leukocytes of the guinea pig. Lab Invest (1969) 1.25
Endocytosis of fibrinogen into megakaryocyte and platelet alpha-granules is mediated by alpha IIb beta 3 (glycoprotein IIb-IIIa) Blood (1993) 1.25
A differential role for cell shape in neutrophil tethering and rolling on endothelial selectins under flow. J Immunol (1996) 1.24
Cysteine protease inhibitors alter Golgi complex ultrastructure and function in Trypanosoma cruzi. J Cell Sci (1998) 1.20
Absence of platelet membrane glycoproteins IIb/IIIa from monocytes. J Exp Med (1985) 1.20
A functional integrin ligand on the surface of platelets: intercellular adhesion molecule-2. J Clin Invest (1994) 1.20
Immunohistochemical localization of membrane and alpha-granule proteins in human megakaryocytes: application to plastic-embedded bone marrow biopsy specimens. Blood (1986) 1.19
Glycoprotein V-deficient platelets have undiminished thrombin responsiveness and Do not exhibit a Bernard-Soulier phenotype. Blood (1999) 1.14
Histochemistry of Hodgkin's disease. Cancer Treat Rep (1982) 1.14
Subcellular distribution of docking/fusion proteins in neutrophils, secretory cells with multiple exocytic compartments. J Immunol (1995) 1.14
Incorporation of a circulating protein into megakaryocyte and platelet granules. Proc Natl Acad Sci U S A (1987) 1.14
Rapid redistribution of clathrin onto macrophage plasma membranes in response to Fc receptor-ligand interaction during frustrated phagocytosis. J Cell Biol (1986) 1.13
Neutrophil granules. Br J Haematol (1975) 1.11
Thrombin receptors on human platelets. Initial localization and subsequent redistribution during platelet activation. J Biol Chem (1997) 1.10
Enzyme histochemistry on bone marrow biopsies: reactions useful in the differential diagnosis of leukemia and lymphoma applied to 2-micron plastic sections. Blood (1980) 1.10
Cytochemical localization of arylsulfatase B in rat basophils and mast cells. J Histochem Cytochem (1980) 1.08
Immunoglobulin G is a platelet alpha granule-secreted protein. J Clin Invest (1985) 1.07
Platelet dense granule membranes contain both granulophysin and P-selectin (GMP-140). Blood (1992) 1.07
Optimal techniques for the immunocytochemical demonstration of beta-thromboglobulin, platelet factor 4, and fibrinogen in the alpha granules of unstimulated platelets. Histochem J (1984) 1.06
Incorporation of intravenously injected albumin, immunoglobulin G, and fibrinogen in guinea pig megakaryocyte granules. J Clin Invest (1989) 1.06
Human neutrophil gelatinase is a component of specific granules. J Clin Invest (1989) 1.04
Electron microscopic demonstration of lysosomal inclusion bodies in lung, liver, lymph nodes, and blood leukocytes of patients with amiodarone pulmonary toxicity. Am J Med (1985) 1.04
The discovery of lysosomes. J Cell Biol (1981) 1.03
Ultrastructural localization of peroxidase in leukocytes of rat bone marrow and blood. Anat Rec (1977) 1.02
Gray platelet syndrome. Demonstration of alpha granule membranes that can fuse with the cell surface. J Clin Invest (1987) 1.00
Identification of primary lysosomes in human megakaryocytes and platelets. Blood (1982) 0.99
Degranulation and abnormal bactericidal function of granulocytes procured by reversible adhesion to nylon wool. Blood (1976) 0.99
Retraction. Am J Respir Crit Care Med (2000) 0.95
Differences in peroxidase localization of rabbit peritoneal macrophages after surface adherence. Am J Pathol (1978) 0.95
Topographic distribution of a granule membrane protein (GMP-140) that is expressed on the platelet surface after activation: an immunogold-surface replica study. Blood Cells (1986) 0.93
Incorporation of a circulating protein into alpha granules of megakaryocytes. Blood Cells (1989) 0.91
Differentiation of cell surface receptors on normal human bone marrow myeloid precursors. Br J Haematol (1981) 0.89
Kistrin, an integrin antagonist, blocks endocytosis of fibrinogen into guinea pig megakaryocyte and platelet alpha-granules. J Clin Invest (1993) 0.89
Abnormalities in granule formation in acute myelogenous leukemia. Blood (1977) 0.89
Platelet alpha-granule fibrinogen, albumin, and immunoglobulin G are not synthesized by rat and mouse megakaryocytes. J Clin Invest (1990) 0.89
Pathogenesis of one variant of sea-blue histiocytosis. Lab Invest (1975) 0.88
Intracellular localization of pp60c-src in human platelets. Oncogene (1990) 0.88
The cell and molecular biology of apolipoprotein E synthesis by macrophages. Ciba Found Symp (1986) 0.88
Granulophysin is located in the membrane of azurophilic granules in human neutrophils and mobilizes to the plasma membrane following cell stimulation. Am J Pathol (1994) 0.86
Azurophil and specific granules of blood neutrophils in chronic myelogenous leukemia: an ultrastructural and cytochemical analysis. Blood (1974) 0.85
Selective abnormalities of azurophil and specific granules of human neutrophilic leukocytes. Fed Proc (1981) 0.85
Multimerin is found in the alpha-granules of resting platelets and is synthesized by a megakaryocytic cell line. J Clin Invest (1993) 0.85
Auer rod-like inclusions in prolymphocytic leukemia. Acta Haematol (1987) 0.83
Ultrastructural localization of acid phosphatase in rosetted T and B lymphocytes of normal human blood. Am J Pathol (1981) 0.83
Lipid peroxidation and morphological changes in mammalian cells treated with the glutathione oxidant, diamide. Exp Cell Res (1977) 0.83
In vivo defibrination results in markedly decreased amounts of fibrinogen in rat megakaryocytes and platelets. Am J Pathol (1990) 0.82
Decreased content and surface expression of alpha-granule membrane protein GMP-140 in one of two types of platelet alpha delta storage pool deficiency. J Clin Invest (1991) 0.82
Monoclonal antibodies bound to subunits of the integrin GPIIb-IIIa are internalized and interfere with filopodia formation and platelet aggregation. Blood (1990) 0.81
Glucose-6-phosphatase as a cytochemical marker of endoplasmic reticulum in human leukocytes and platelets. J Histochem Cytochem (1984) 0.81
Primary lysosomes of blood leukocytes. Front Biol (1976) 0.81
Factor V is complexed with multimerin in resting platelet lysates and colocalizes with multimerin in platelet alpha-granules. J Biol Chem (1995) 0.81
Directed exocytosis of secretory granules containing apolipoprotein E to the adherent surface and basal vacuoles of macrophages spreading on immobile immune complexes. Am J Pathol (1989) 0.81
Differentiation of human neutrophilic granulocytes: normal and abnormal. Prog Clin Biol Res (1977) 0.80
Ultrastructure of rat megakaryocytes after prolonged thrombocytopenia. J Ultrastruct Res (1977) 0.80
The origin of platelet alpha-granule proteins. Prog Clin Biol Res (1990) 0.80
Immunogold-surface replica study of ADP-induced ligand binding and fibrinogen receptor clustering in human platelets. Am J Anat (1989) 0.79
Membrane surface proteinase 3 expression and intracytoplasmic immunoglobulin on neutrophils from patients with ANCA-associated vasculitides. Adv Exp Med Biol (1993) 0.79