Published in Cell on April 01, 1975
Cell surface protein partially restores morphology, adhesiveness, and contact inhibition of movement to transformed fibroblasts. Proc Natl Acad Sci U S A (1976) 4.32
Virus-specific proteins in the plasma membrane of cells lytically infected or transformed by pol-oma virus. Proc Natl Acad Sci U S A (1977) 3.68
External fibronectin of cultured human fibroblasts is predominantly a matrix protein. J Cell Biol (1978) 2.70
Surface distribution of LETS protein in relation to the cytoskeleton of normal and transformed cells. J Cell Biol (1977) 2.40
Collagen reduces glycosaminoglycan degradation by cultured mammary epithelial cells: possible mechanism for basal lamina formation. Proc Natl Acad Sci U S A (1979) 2.05
Polyoma virus middle T antigen: relationship to cell membranes and apparent lack of ATP-binding activity. Mol Cell Biol (1982) 1.87
Outer membrane protein YadA of enteropathogenic yersiniae mediates specific binding to cellular but not plasma fibronectin. Infect Immun (1993) 1.41
The emergence of integrins: a personal and historical perspective. Matrix Biol (2004) 1.18
Divergent fates of von Willebrand factor and its propolypeptide (von Willebrand antigen II) after secretion from endothelial cells. Proc Natl Acad Sci U S A (1987) 1.10
Stem cells in rat mammary development and cancer: a review. J R Soc Med (1980) 1.10
Biosynthesis and release of glycoproteins by human skin fibroblasts in culture. Biochem J (1977) 1.08
Fate of surface proteins of rabbit polymorphonuclear leukocytes during phagocytosis. I. Identification of surface proteins. J Cell Biol (1979) 1.03
Differences in intracellular distribution of plasminogen activator in growing, confluent, and transformed 3T3 cells. Proc Natl Acad Sci U S A (1979) 0.99
Isolation and characterization of epithelial stem-cell cell lines from the rat mammary gland. Br J Cancer (1980) 0.86
Regulation of plasminogen activator in 3T3 cells: effect of phorbol myristate acetate on subcellular distribution and molecular weight. J Cell Biol (1981) 0.83
The surface glycoproteins of human skin fibroblasts detected after electrophoresis by the binding of peanut (Arachis hypogaea) agglutinin and Ricinus communis (castor-bean) agglutinin I. Biochem J (1982) 0.82
Polypeptide heterogeneity of hamster and calf fibronectins. Biochem J (1980) 0.81
Association of the transformation-specific protein pp60src with the membrane of an avian sarcoma virus. J Virol (1981) 0.78
Imperial Cancer Research Fund British Association for Cancer Research. Joint symposium held at the Royal College of Surgeons, Lincolns Inn Fields, London 30 November--1 December 1978. Abstracts of papers. Br J Cancer (1979) 0.75
The fluidity of normal and virus-transformed cell plasma membrane. Biochem J (1976) 0.75
Covalent attachment of enzyme as a membrane-label for viable eucaryotic cells. J Cell Biol (1979) 0.75
Comparative genomics of the eukaryotes. Science (2000) 26.62
Integrins: a family of cell surface receptors. Cell (1987) 21.14
Genomic analysis of metastasis reveals an essential role for RhoC. Nature (2000) 10.11
Defensins. Natural peptide antibiotics of human neutrophils. J Clin Invest (1985) 8.63
Fibronectins: multifunctional modular glycoproteins. J Cell Biol (1982) 8.05
Alteration of cell-surface proteins by viral transformation and by proteolysis. Proc Natl Acad Sci U S A (1973) 6.98
Defects in mesoderm, neural tube and vascular development in mouse embryos lacking fibronectin. Development (1993) 6.56
Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts. Nature (1999) 6.50
Thrombospondin-1 is a major activator of TGF-beta1 in vivo. Cell (1998) 6.44
Three different fibronectin mRNAs arise by alternative splicing within the coding region. Cell (1983) 6.27
Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice. Cell (1993) 6.05
Origin of granules in polymorphonuclear leukocytes. Two types derived from opposite faces of the Golgi complex in developing granulocytes. J Cell Biol (1966) 5.96
Fibronectin/integrin interaction induces tyrosine phosphorylation of a 120-kDa protein. Cell Regul (1991) 5.80
Beta3-integrin-deficient mice are a model for Glanzmann thrombasthenia showing placental defects and reduced survival. J Clin Invest (1999) 5.65
Coloboma, congenital heart disease, and choanal atresia with multiple anomalies: CHARGE association. J Pediatr (1981) 5.35
Structure of integrin, a glycoprotein involved in the transmembrane linkage between fibronectin and actin. Cell (1986) 5.29
Differences in enzyme content of azurophil and specific granules of polymorphonuclear leukocytes. II. Cytochemistry and electron microscopy of bone marrow cells. J Cell Biol (1968) 5.20
The development of neutrophilic polymorphonuclear leukocytes in human bone marrow. J Exp Med (1971) 4.98
The Talin head domain binds to integrin beta subunit cytoplasmic tails and regulates integrin activation. J Biol Chem (1999) 4.92
Incidence of fetal alcohol syndrome and prevalence of alcohol-related neurodevelopmental disorder. Teratology (1997) 4.86
10 nm filaments in normal and transformed cells. Cell (1978) 4.77
GMP-140, a platelet alpha-granule membrane protein, is also synthesized by vascular endothelial cells and is localized in Weibel-Palade bodies. J Clin Invest (1989) 4.59
Mice lacking beta3 integrins are osteosclerotic because of dysfunctional osteoclasts. J Clin Invest (2000) 4.54
Susceptibility to infection and altered hematopoiesis in mice deficient in both P- and E-selectins. Cell (1996) 4.52
Cell adhesion events mediated by alpha 4 integrins are essential in placental and cardiac development. Development (1995) 4.44
Cell surface proteins and malignant transformation. Biochim Biophys Acta (1976) 4.33
P-selectin glycoprotein ligand-1 mediates rolling of human neutrophils on P-selectin. J Cell Biol (1995) 4.31
Embryonic mesodermal defects in alpha 5 integrin-deficient mice. Development (1993) 4.22
Extensive vasculogenesis, angiogenesis, and organogenesis precede lethality in mice lacking all alpha v integrins. Cell (1998) 4.20
The structure of human thrombospondin, an adhesive glycoprotein with multiple calcium-binding sites and homologies with several different proteins. J Cell Biol (1986) 4.16
Relationships between fibronectin (LETS protein) and actin. Cell (1978) 4.12
Plakoglobin: a protein common to different kinds of intercellular adhering junctions. Cell (1986) 4.01
Thrombospondin-1 is required for normal murine pulmonary homeostasis and its absence causes pneumonia. J Clin Invest (1998) 4.00
A mouse model of severe von Willebrand disease: defects in hemostasis and thrombosis. Proc Natl Acad Sci U S A (1998) 3.54
Lymphoid cells recognize an alternatively spliced segment of fibronectin via the integrin receptor alpha 4 beta 1. Cell (1990) 3.46
Integrin-mediated signals regulated by members of the rho family of GTPases. J Cell Biol (1998) 3.46
Reappearance of an embryonic pattern of fibronectin splicing during wound healing in the adult rat. J Cell Biol (1989) 3.44
Stimulated mobilization of monocyte Mac-1 and p150,95 adhesion proteins from an intracellular vesicular compartment to the cell surface. J Clin Invest (1987) 3.40
Developmental defects in mouse embryos lacking N-cadherin. Dev Biol (1997) 3.39
Restoration of normal morphology, adhesion and cytoskeleton in transformed cells by addition of a transformation-sensitive surface protein. Cell (1977) 3.36
Antibodies to the conserved cytoplasmic domain of the integrin beta 1 subunit react with proteins in vertebrates, invertebrates, and fungi. J Cell Biol (1988) 3.35
Temporal changes in pH within the phagocytic vacuole of the polymorphonuclear neutrophilic leukocyte. J Cell Biol (1973) 3.34
CHARGE association: an update and review for the primary pediatrician. Clin Pediatr (Phila) (1998) 3.33
Hematopoietic progenitor cell rolling in bone marrow microvessels: parallel contributions by endothelial selectins and vascular cell adhesion molecule 1. J Exp Med (1998) 3.26
PTEN mutation spectrum and genotype-phenotype correlations in Bannayan-Riley-Ruvalcaba syndrome suggest a single entity with Cowden syndrome. Hum Mol Genet (1999) 3.22
Angelman and Prader-Willi syndromes share a common chromosome 15 deletion but differ in parental origin of the deletion. Am J Med Genet (1989) 3.22
Regulation of alternative pre-mRNA splicing by a novel repeated hexanucleotide element. Genes Dev (1994) 3.20
Differences in enzyme content of azurophil and specific granules of polymorphonuclear leukocytes. I. Histochemical staining of bone marrow smears. J Cell Biol (1968) 3.13
Changes in integrin receptors on oncogenically transformed cells. Cell (1989) 3.09
Sequential degranulation of the two types of polymorphonuclear leukocyte granules during phagocytosis of microorganisms. J Cell Biol (1973) 3.05
Proteus syndrome: diagnostic criteria, differential diagnosis, and patient evaluation. Am J Med Genet (1999) 3.02
A platelet alpha-granule membrane protein (GMP-140) is expressed on the plasma membrane after activation. J Cell Biol (1985) 3.02
Sequence and domain structure of talin. Nature (1990) 2.98
Segregation and packaging of granule enzymes in eosinophilic leukocytes. J Cell Biol (1970) 2.94
Differentiation of monocytes. Origin, nature, and fate of their azurophil granules. J Cell Biol (1971) 2.86
Quantitative calibration and use of DNA probes for investigating chromosome abnormalities in the Prader-Willi syndrome. Am J Med Genet (1989) 2.83
Thrombospondin-1 suppresses spontaneous tumor growth and inhibits activation of matrix metalloproteinase-9 and mobilization of vascular endothelial growth factor. Proc Natl Acad Sci U S A (2001) 2.82
Cell attachment to thrombospondin: the role of ARG-GLY-ASP, calcium, and integrin receptors. J Cell Biol (1988) 2.72
Persistence of platelet thrombus formation in arterioles of mice lacking both von Willebrand factor and fibrinogen. J Clin Invest (2000) 2.68
The combined role of P- and E-selectins in atherosclerosis. J Clin Invest (1998) 2.53
Syndecan-4 signals cooperatively with integrins in a Rho-dependent manner in the assembly of focal adhesions and actin stress fibers. Proc Natl Acad Sci U S A (1999) 2.47
alpha3beta1 Integrin is required for normal development of the epidermal basement membrane. J Cell Biol (1997) 2.46
Surface distribution of LETS protein in relation to the cytoskeleton of normal and transformed cells. J Cell Biol (1977) 2.40
Self-complementary oligopeptide matrices support mammalian cell attachment. Biomaterials (1995) 2.40
Platelets roll on stimulated endothelium in vivo: an interaction mediated by endothelial P-selectin. Proc Natl Acad Sci U S A (1995) 2.37
Extensive disulfide bonding at the mammalian cell surface. Proc Natl Acad Sci U S A (1977) 2.32
Fibronectin binds to some bacteria but does not promote their uptake by phagocytic cells. Science (1983) 2.31
Cross-linking of fibronectin to sulfated proteoglycans at the cell surface. Cell (1979) 2.28
GLI3 frameshift mutations cause autosomal dominant Pallister-Hall syndrome. Nat Genet (1997) 2.28
Plasma fibronectin is synthesized and secreted by hepatocytes. J Biol Chem (1983) 2.25
Evaluation of mental retardation: recommendations of a Consensus Conference: American College of Medical Genetics. Am J Med Genet (1997) 2.19
The human antibacterial cathelicidin, hCAP-18, is synthesized in myelocytes and metamyelocytes and localized to specific granules in neutrophils. Blood (1997) 2.16
Targeted mutation of TNF receptor I rescues the RelA-deficient mouse and reveals a critical role for NF-kappa B in leukocyte recruitment. J Immunol (2001) 2.16
Clinical and molecular studies in full trisomy 22: further delineation of the phenotype and review of the literature. Am J Med Genet (1995) 2.15
Fibronectins are essential for heart and blood vessel morphogenesis but are dispensable for initial specification of precursor cells. Blood (1997) 2.15
Identification of neutrophil gelatinase-associated lipocalin as a novel matrix protein of specific granules in human neutrophils. Blood (1994) 2.14
Retraction. Am J Respir Crit Care Med (2000) 2.14
Density and cell cycle dependence of cell surface proteins in hamster fibroblasts. Cell (1974) 2.13
Hemostasis in the mouse (Mus musculus): a review. Thromb Haemost (1999) 2.13
A large glycoprotein lost from the surfaces of transformed cells. Ann N Y Acad Sci (1978) 2.11
Precocious mammary gland development in P-cadherin-deficient mice. J Cell Biol (1997) 2.10
Cell-type-specific fibronectin subunits generated by alternative splicing. J Biol Chem (1986) 2.09
Transepithelial transport of a viral membrane glycoprotein implanted into the apical plasma membrane of Madin-Darby canine kidney cells. I. Morphological evidence. J Cell Biol (1983) 2.07
Redistribution of alpha-granules and their contents in thrombin-stimulated platelets. J Cell Biol (1984) 2.06
Platelets adhere to and translocate on von Willebrand factor presented by endothelium in stimulated veins. Blood (2000) 2.05
An integrin receptor on normal and thrombasthenic platelets that binds thrombospondin. Blood (1989) 2.05
Multiple sites of alternative splicing of the rat fibronectin gene transcript. EMBO J (1987) 2.03
Expression of normal and mutant avian integrin subunits in rodent cells. J Cell Biol (1989) 2.03
Differential requirements for alpha4 integrins during fetal and adult hematopoiesis. Cell (1996) 2.01
Restriction fragment length polymorphisms within proximal 15q and their use in molecular cytogenetics and the Prader-Willi syndrome. Am J Med Genet (1989) 2.00
A single rat fibronectin gene generates three different mRNAs by alternative splicing of a complex exon. Proc Natl Acad Sci U S A (1984) 2.00
Quantitation of L-selectin distribution on human leukocyte microvilli by immunogold labeling and electron microscopy. J Histochem Cytochem (1996) 1.97
Analysis of platelet adhesion with a radioactive chemical crosslinking reagent: interaction of thrombospondin with fibronectin and collagen. Cell (1982) 1.96
Talin contains three actin-binding sites each of which is adjacent to a vinculin-binding site. J Cell Sci (1996) 1.95
Mapping of the functional determinants of the integrin beta 1 cytoplasmic domain by site-directed mutagenesis. Cell Regul (1990) 1.94
Interaction of fibronectin with its receptor on platelets. Cell (1985) 1.92
Protein glycosylation in the malaria parasite. Parasitol Today (1999) 1.90
Purification and characterization of human lysosomal membrane glycoproteins. Arch Biochem Biophys (1989) 1.90
Changes in pH within the phagocytic vacuoles of human neutrophils and monocytes. Lab Invest (1978) 1.88