Published in J Am Chem Soc on August 22, 1973
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Biosynthesis of vitamin B12: concerning the origin of the methine protons of the corrin nucleus. Proc Natl Acad Sci U S A (1987) 1.14
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Aflatoxin and deconstruction of type I, iterative polyketide synthase function. Nat Prod Rep (2014) 0.86
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Predictive, structure-based model of amino acid recognition by nonribosomal peptide synthetase adenylation domains. Chem Biol (2000) 4.59
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Current intensity and oxytocin release after electroconvulsive therapy. Biol Psychiatry (1993) 2.04
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Spectroscopic studies of substrate interactions with clavaminate synthase 2, a multifunctional alpha-KG-dependent non-heme iron enzyme: correlation with mechanisms and reactivities. J Am Chem Soc (2001) 1.53
Nucleotide sequence of a cDNA encoding the vacuolar protein strictosidine synthase from Catharanthus roseus. Nucleic Acids Res (1990) 1.52
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Carbon-13 as a label in biosynthetic studies. Science (1974) 1.45
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Two isozymes of clavaminate synthase central to clavulanic acid formation: cloning and sequencing of both genes from Streptomyces clavuligerus. Biochemistry (1992) 1.34
Enzymatic synthesis and structure of precorrin-3, a trimethyldipyrrocorphin intermediate in vitamin B12 biosynthesis. Biochemistry (1992) 1.23
Conformations of human apolipoprotein E(263-286) and E(267-289) in aqueous solutions of sodium dodecyl sulfate by CD and 1H NMR. Biochemistry (1996) 1.19
Demonstration of the catalytic roles and evidence for the physical association of type I fatty acid synthases and a polyketide synthase in the biosynthesis of aflatoxin B1. Chem Biol (1996) 1.19
Engineering Escherichia coli for the synthesis of taxadiene, a key intermediate in the biosynthesis of taxol. Bioorg Med Chem (2001) 1.15
A new type of cytotoxic immunosuppressive agent: 3-acetyl-5-(4-fluorbenzylidiene)4-hydroxy-2-oxo-2:5-dihydrothiophen. Nature (1966) 1.15
Structure of beta-lactam synthetase reveals how to synthesize antibiotics instead of asparagine. Nat Struct Biol (2001) 1.15
The preparation and structure of hetacillin. J Org Chem (1966) 1.12
Expression of 9 Salmonella typhimurium enzymes for cobinamide synthesis. Identification of the 11-methyl and 20-methyl transferases of corrin biosynthesis. FEBS Lett (1992) 1.12
Enzymatic synthesis of dihydrosirohydrochlorin (precorrin-2) and of a novel pyrrocorphin by uroporphyrinogen III methylase. FEBS Lett (1990) 1.11
Applications of 13C NMR to metabolic studies. Annu Rev Biophys Bioeng (1981) 1.11
Variation in rates of electroconvulsive therapy use among consultant teams in Edinburgh (1993-1996). J Affect Disord (2000) 1.11
13C NMR study of the ionizations within a trypsin-chloromethyl ketone inhibitor complex. Biochemistry (1985) 1.10
Cloning, sequencing, and expression of the uroporphyrinogen III methyltransferase cobA gene of Propionibacterium freudenreichii (shermanii). J Bacteriol (1995) 1.10
Purification, characterization, and cloning of an S-adenosylmethionine-dependent 3-amino-3-carboxypropyltransferase in nocardicin biosynthesis. J Biol Chem (1998) 1.09
Identification, cloning, sequencing, and overexpression of the gene encoding proclavaminate amidino hydrolase and characterization of protein function in clavulanic acid biosynthesis. J Bacteriol (1995) 1.08
The mechansim of action of coenzyme B12. The role thioester in a nonenzyme model reaction for coenzyme B12 Dependent isomerization of methylmalony coenzyme A to succinyl coenzyme A. J Am Chem Soc (1977) 1.08
Sterol carrier protein-2: structure reveals function. Cell Mol Life Sci (2002) 1.08
How corrinoids are synthesized without oxygen: nature's first pathway to vitamin B12. Chem Biol (1997) 1.06
Isolation and characterization of the versicolorin B synthase gene from Aspergillus parasiticus. Expansion of the aflatoxin b1 biosynthetic gene cluster. J Biol Chem (1996) 1.06
Biosynthesis of prodigiosin. Incorporation patterns of C-labeled alanine, proline, glycine, and serine elucidated by fourier transform nuclear magnetic resonance. J Am Chem Soc (1973) 1.04
New sesquiterpene alpha-methylene lactones from the Egyptian plant Jasonia candicans. J Nat Prod (1993) 1.04
A new class of antituberculosis agents. J Med Chem (2000) 1.03
Cleavage by calicheamicin gamma 1I of DNA in a nucleosome formed on the 5S RNA gene of Xenopus borealis. Biochemistry (1995) 1.02
Multiple biosynthetic pathways for vitamin B12: variations on a central theme. Vitam Horm (2001) 1.00
Sequence of the Candida albicans erg7 gene. Gene (1993) 1.00
Hexanoate synthase, a specialized type I fatty acid synthase in aflatoxin B1 biosynthesis. Bioorg Chem (2001) 1.00
Evidence-based psychiatry--do psychiatrists want it and can they do it? Health Bull (Edinb) (2000) 0.99
Carbon-13 Fourier transform nuclear magnetic resonance. 8. Role of steric and electric field effects in fatty acid spectra. J Org Chem (1974) 0.99
5-Aminolevulinic acid formation from glutamate via the C5 pathway in Clostridium thermoaceticum. FEBS Lett (1988) 0.99
Biosynthesis of vitamin B12: concerning the identity of the two-carbon fragment eliminated during anaerobic formation of cobyrinic acid. Proc Natl Acad Sci U S A (1996) 0.99
Overexpression, purification, and characterization of the thermostable mevalonate kinase from Methanococcus jannaschii. Protein Expr Purif (1999) 0.99
Expansion of the clavulanic acid gene cluster: identification and in vivo functional analysis of three new genes required for biosynthesis of clavulanic acid by Streptomyces clavuligerus. J Bacteriol (2000) 0.99
A 13C-n.m.r. investigation of ionizations within a trypsin-inhibitor complex. Evidence that the pKa of histidine-57 is raised by interaction with the hemiketal oxyanion. Biochem J (1985) 0.97
Conformation of human apolipoprotein C-I in a lipid-mimetic environment determined by CD and NMR spectroscopy. Biochemistry (1999) 0.97
Kinetic mechanism of the beta-lactam synthetase of Streptomyces clavuligerus. Biochemistry (2000) 0.97
Conformation of human serum apolipoprotein A-I(166-185) in the presence of sodium dodecyl sulfate or dodecylphosphocholine by 1H-NMR and CD. Evidence for specific peptide-SDS interactions. Biochim Biophys Acta (1996) 0.97
A single monomeric iron center in clavaminate synthase catalyzes three nonsuccessive oxidative transformations. Bioorg Med Chem (1996) 0.96
Requirement of monooxygenase-mediated steps for sterigmatocystin biosynthesis by Aspergillus nidulans. Appl Environ Microbiol (2000) 0.96
Biosynthesis of corrins. I. Experiments with 14-C porphobilinogen and 14-C uroporphyrinogens. J Am Chem Soc (1974) 0.96
Letter: Acetyl transfer reaction in catechol acetate malonate. A model for the biosynthesis of polyketides and fatty acids. J Am Chem Soc (1975) 0.96
Overexpression in Escherichia coli of 12 vitamin B12 biosynthetic enzymes. Protein Expr Purif (1995) 0.95
Elucidation of the order of oxidations and identification of an intermediate in the multistep clavaminate synthase reaction. Biochemistry (1991) 0.95
Achieving natural product synthesis and diversity via catalytic networking ex vivo. Chem Biol (1996) 0.94
Genetically engineered synthesis of precorrin-6x and the complete corrinoid, hydrogenobyrinic acid, an advanced precursor of vitamin B12. Chem Biol (1994) 0.94
Pharmacological studies with vinblastine in the dog. Cancer Res (1975) 0.93
Concerning the biosynthesis of vitamin B12. Trans N Y Acad Sci (1973) 0.93
The helix-hinge-helix structural motif in human apolipoprotein A-I determined by NMR spectroscopy. Biochemistry (1997) 0.92
Secondary structure of human apolipoprotein A-I(1-186) in lipid-mimetic solution. FEBS Lett (2001) 0.92
Holo-sterol carrier protein-2. (13)C NMR investigation of cholesterol and fatty acid binding sites. J Biol Chem (1999) 0.92
Enzymatic synthesis of S-adenosyl-L-methionine on the preparative scale. Bioorg Med Chem (1996) 0.91
A rapid direct assay for uroporphyrinogen III cosynthetase. FEBS Lett (1980) 0.90
Purification and properties of strictosidine synthetase (an enzyme condensing tryptamine and secologanin) from Catharanthus roseus cultured cells. Biochemistry (1979) 0.90
Expression and purification of two isozymes of clavaminate synthase and initial characterization of the iron binding site. General error analysis in polymerase chain reaction amplification. J Biol Chem (1995) 0.90
Diastereotopic covalent binding of the natural inhibitor leupeptin to trypsin: detection of two interconverting hemiacetals by solution and solid-state NMR spectroscopy. Biochemistry (1991) 0.90
Crystal structure of precorrin-8x methyl mutase. Structure (2001) 0.89
Definition of the redox states of cobalt-precorrinoids: investigation of the substrate and redox specificity of CbiL from Salmonella typhimurium. Biochemistry (1998) 0.89
Studies on almond emulsin beta-D-glucosidase. II. Kinetic evidence for independent glucosidase and galactosidase sites. Biochim Biophys Acta (1977) 0.89
A deuterium NMR study of labelled n-alkanol anesthetics in a model membrane. Chem Phys Lipids (1986) 0.89
Purification and characterization of clavaminate synthase from Streptomyces antibioticus. A multifunctional enzyme of clavam biosynthesis. J Biol Chem (1995) 0.88
The structure and chemistry of hirsutic acid. Tetrahedron (1967) 0.87
Conformation of two peptides corresponding to human apolipoprotein C-I residues 7-24 and 35-53 in the presence of sodium dodecyl sulfate by CD and NMR spectroscopy. Biochemistry (1995) 0.87
Hydroxyl radical footprinting of calicheamicin. Relationship of DNA binding to cleavage. Biochemistry (1994) 0.87
Heterologous expression, isolation, and characterization of versicolorin B synthase from Aspergillus parasiticus. A key enzyme in the aflatoxin B1 biosynthetic pathway. J Biol Chem (1997) 0.86
Characterization of Alkaloid Uptake by Catharanthus roseus (L.) G. Don Protoplasts. Plant Physiol (1988) 0.86
The sterol carrier protein-2 fatty acid binding site: an NMR, circular dichroic, and fluorescence spectroscopic determination. Biochemistry (1997) 0.86
Fluorescence-based method for selection of recombinant plasmids. Biotechniques (1995) 0.86
Purification and characterization of versicolorin B synthase from Aspergillus parasiticus. Catalysis of the stereodifferentiating cyclization in aflatoxin biosynthesis essential to DNA interaction. Biochemistry (1996) 0.86
Deuterium NMR study of the effect of n-alkanol anesthetics on a model membrane system. Biochim Biophys Acta (1985) 0.86
Diversity in cyclic sesquiterpene production by Gossypium hirsutum. Phytochemistry (1995) 0.86
The Edinburgh Primary Care Depression Study: personality disorder and outcome. Br J Psychiatry (1995) 0.86
Surface diffusion in human serum lipoproteins. Biochem Biophys Res Commun (1987) 0.85
Cryoenzymology of trypsin. A detailed kinetic study of the trypsin-catalysed hydrolysis of N-alpha-benzyloxycarbonyl-L-lysine p-nitrophenyl ester at low temperatures. Biochem J (1983) 0.85
13C NMR study of the stereospecificity of the thiohemiacetals formed on inhibition of papain by specific enantiomeric aldehydes. Biochemistry (1986) 0.85
Sirohydrochlorin. Prosthetic group of a sulfite reductase enzyme and its role in the biosynthesis of vitamin B12. J Am Chem Soc (1978) 0.85
Biosynthesis of corrins. II. Incorporation of 13C-labeled substrates in vitamins B12. J Am Chem Soc (1974) 0.85
Purification of an indole alkaloid biosynthetic enzyme, strictosidine synthase, from a recombinant strain of Escherichia coli. Protein Expr Purif (1992) 0.84
13C nuclear magnetic resonance studies of anaerobic glycolysis in Trypanosoma brucei spp. Biosci Rep (1983) 0.84