Competition for antigen by cell populations having receptors with the same specificity but of different idiotype.

Presence on idiotype-specific suppressor T cells of receptors that interact with molecules bearing the idiotype. J Exp Med (1977) 2.29

Suppression of idiotype and generation of suppressor T cells with idiotype-conjugated thymocytes. J Exp Med (1979) 1.56

Binding to idiotypic determinants of large proportions of thymus-derived lymphocytes in idiotypically suppressed mice. Proc Natl Acad Sci U S A (1977) 1.26

Complete inhibition of the expression of an idiotype by a mechanism of B-cell dominance. J Exp Med (1977) 1.11

Mechanisms of idiotype suppression. I. In vitro generation of idiotype-specific suppressor T cells by anti-idiotype antibodies and specific antigen. J Exp Med (1979) 1.04

Effect of idiotype-specific suppressor T cells on primary and secondary responses. J Exp Med (1978) 0.98

Profile of Pamela J. Fraker. Interview by Tinsley H. Davis. Proc Natl Acad Sci U S A (2012) 0.75

Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphrenylglycoluril. Biochem Biophys Res Commun (1978) 32.33

Quantitative investigations of idiotypic antibodies. VI. Idiotypic specificity as a potential genetic marker for the variable regions of mouse immunoglobulin polypeptide chains. J Exp Med (1972) 4.84

Evidence for the linkage of the IGC H locus to a gene controlling the idiotypic specificity of anti-p-azophenylarsonate antibodies in strain A mice. J Exp Med (1973) 3.18

Quantitative investigations of idiotypic antibodies. I. Analysis of precipitating antibody populations. J Exp Med (1969) 3.10

Quantitative investigations of idiotypic antibodies. IV. Inhibition by specific haptens of the reaction of anti-hapten antibody with its anti-idiotypic antibody. J Exp Med (1970) 3.01

Evidence for control of synthesis of the varible regions of the heavy chains of immunoglobulins G and M by the same gene. Proc Natl Acad Sci U S A (1970) 2.96

Suppression of idiotypic specificities in adult mice by administration of antiidiotypic antibody. J Exp Med (1972) 2.93

Production of large amounts of antibodies in individual mice. J Immunol (1976) 2.93

Comparative evaluation of several DNA binding dyes in the detection of apoptosis-associated chromatin degradation by flow cytometry. Cytometry (1992) 2.30

Presence on idiotype-specific suppressor T cells of receptors that interact with molecules bearing the idiotype. J Exp Med (1977) 2.29

Mechanisms of regulation of cell-mediated immunity. IV. Azobenzenearsonate-specific suppressor factor(s) bear cross-reactive idiotypic determinants the expression of which is linked to the heavy-chain allotype linkage group of genes. J Exp Med (1979) 2.22

Distribution of a cross-reactive idiotypic specificity in inbred strains of mice. J Exp Med (1973) 2.13

Implications of the presence of an internal image of the antigen in anti-idiotypic antibodies: possible application to vaccine production. Clin Immunol Immunopathol (1981) 2.05

Segregation at a locus determining an immunoglobulin genetic marker for the light chain variable region affects inheritance of expression of an idiotype. Proc Natl Acad Sci U S A (1977) 1.97

Studies of structure and immunosuppression of cross-reactive idiotype in strain A mice. Immunol Rev (1977) 1.86

Apoptosis plays a distinct role in the loss of precursor lymphocytes during zinc deficiency in mice. J Nutr (2002) 1.76

Enhancement by reducing agents of the transformation of human and rabbit peripheral lymphocytes. J Immunol (1970) 1.73

Isolation from individual A/J mice of anti-rho-azophenylarsonate antibodies bearing a cross-reactive idiotype. J Exp Med (1975) 1.68

Requirement for cross-linkage in the stimulation of transformation of rabbit peripheral lymphocytes by antiglobulin reagents. J Immunol (1970) 1.68

Frequency of occurrence of idiotypes associated with anti-p-azophenylarsonate antibodies arising in mice immunologically suppressed with respect to a cross-reactive idiotype. J Exp Med (1977) 1.67

Quantitative investigations of idiotypic antibodies. II. Nonprecipitating antibodies. J Exp Med (1970) 1.63

Antigen- and receptor-driven regulatory mechanisms. I. Induction of suppressor T cells with anti-idiotypic antibodies. J Exp Med (1979) 1.62

Evaluation of glucocorticoid-induced DNA fragmentation in mouse thymocytes by flow cytometry. Cell Prolif (1991) 1.60

Isolation and fractionation of the photosynthetic membranous organelles from Rhodopseudomonas spheroides. J Bacteriol (1971) 1.58

Preparation of F(ab')2 fragments from mouse IgG of various subclasses. J Immunol Methods (1983) 1.57

Suppression of idiotype and generation of suppressor T cells with idiotype-conjugated thymocytes. J Exp Med (1979) 1.56

Immunological suppression of idiotypic specificities. Transplant Rev (1975) 1.55

Relative labilities of the two types of interchain disulfide bond of rabbit gamma G-immunoglobulin. J Biol Chem (1965) 1.53

Heterogeneity of an intrastrain cross-reactive idiotype associated with anti-p-azophenylarsonate antibodies of A/J mice. J Immunol (1980) 1.51

Selective suppression of the major idiotypic component of an antihapten response by soluble T cell-derived factors with idiotypic or anti-idiotypic receptors. J Exp Med (1980) 1.47

Quantitative investigations of idiotypic antibodies. 3. Persistence and variations of idiotypic specificities during the course of immunization. J Exp Med (1970) 1.43

Antigen- and receptor-driven regulatory mechanisms. II. Induction of suppressor T cells with idiotype-coupled syngeneic spleen cells. J Exp Med (1979) 1.42

Antigen- and receptor-driven regulatory mechanisms. VIII. Suppression of idiotype-negative, p-azobenzenearsonate-specific T cells results from the interaction of an anti-idiotypic second-order T suppressor cell with a cross-reactive-idiotype-positive, p-azobenzenearsonate-primed T cell target. J Exp Med (1981) 1.42

Zinc: health effects and research priorities for the 1990s. Environ Health Perspect (1994) 1.42

Structural studies on induced antibodies with defined idiotypic specificities. IX. Framework differences in the heavy- and light-chain-variable regions of monoclonal anti-p-azophenylarsonate antibodies from A/J mice differing with respect to a cross-reactive idiotype. J Exp Med (1980) 1.40

Requirements for prolonged suppression of an idiotypic specificity in adult mice. J Exp Med (1973) 1.38

Rapid quantitation of apoptosis in pure and heterogeneous cell populations using flow cytometry. J Immunol Methods (1994) 1.36

Three-dimensional structure of Fab R19.9, a monoclonal murine antibody specific for the p-azobenzenearsonate group. Proc Natl Acad Sci U S A (1989) 1.35

SEROLOGIC STUDIES OF PROTEOLYTIC FRAGMENTS OF RABBIT AGGLUTINATING ANTIBODIES. J Clin Invest (1962) 1.31

Clearance of IgE from serum of normal and hybridoma-bearing mice. J Immunol (1985) 1.30

Effect of zinc deficiency on the immune response of the young adult A/J mouse. J Nutr (1977) 1.29

Interrelationships between zinc and immune function. Fed Proc (1986) 1.29

Isotype switching of an immunoglobulin heavy chain transgene occurs by DNA recombination between different chromosomes. Cell (1990) 1.27

Binding to idiotypic determinants of large proportions of thymus-derived lymphocytes in idiotypically suppressed mice. Proc Natl Acad Sci U S A (1977) 1.26

Amino Acid Composition of Univalent Fragments of Rabbit Antibody. Science (1963) 1.25

Crystals of fragment Fab': preparation from pepsin digests of human IgG myeloma proteins. Nature (1969) 1.24

Antigen- and receptor-driven regulatory mechanisms. VII. H-2-restricted anti-idiotypic suppressor factor from efferent suppressor T cells. J Exp Med (1981) 1.23

Isotype switching by a microinjected mu immunoglobulin heavy chain gene in transgenic mice. Proc Natl Acad Sci U S A (1989) 1.23

Immunological activity of cytochrome c. 3. Enhancement of antibody detection and immune response initiation by cytochrome c polymers. J Biol Chem (1970) 1.20

Individual antigenic specificity of immunoglobulins. Adv Immunol (1971) 1.19

Heterogeneity in the complementation of polypeptide subunits of a purified antibody isolated from an individual rabbit. J Immunol (1966) 1.19

Allotypic markers on Fab fragments of mouse immunoglobulins. J Immunol (1974) 1.18

Chronic elevation of plasma corticosterone causes reductions in the number of cycling cells of the B lineage in murine bone marrow and induces apoptosis. Immunology (1993) 1.17

Studies of a cross-reactive idiotype associated with anti-para-azophenylarsonate antibodies of A/J mice. Ann Immunol (Paris) (1976) 1.16

Regulation of immunity to the azobenzenearsonate hapten. Adv Immunol (1982) 1.16

Further characterization of the role of corticosterone in the loss of humoral immunity in zinc-deficient A/J mice as determined by adrenalectomy. J Immunol (1980) 1.14

Immunological activity of cytochrome c. I. Precipitating antibodies to monomeric vertebrate cytochromes c. J Biol Chem (1970) 1.14

Antigen- and receptor-driven regulatory mechanisms. V. The failure of idiotype-coupled spleen cells to induce unresponsiveness in animals lacking the appropriate VH genes is caused by the lack of idiotype-matched targets. J Exp Med (1980) 1.12

Complete inhibition of the expression of an idiotype by a mechanism of B-cell dominance. J Exp Med (1977) 1.11

Relationship of VH and VL genes encoding three idiotypic families of anti-p-azobenzenearsonate antibodies. Proc Natl Acad Sci U S A (1986) 1.11

Structural studies on induced antibodies with defined idiotypic specificities. I. The heavy chains of anti-p-azophenylarsonate antibodies from A/J mice bearing a cross-reactive idiotype. J Immunol (1975) 1.10

Differences in amino acid composition of rabbit gamma-G-immunoglobulin light polypeptide chains controlled by allelic genes. Immunochemistry (1965) 1.10

Reaction of anti-idiotypic antibody with the hapten-binding site of a myeloma protein. Proc Natl Acad Sci U S A (1971) 1.09

Nature of anti-hapten antibodies arising after immune suppression of a set of cross-raactive idiotypic specificities. Eur J Immunol (1973) 1.09

Relative combining affinities of anti-p-azophenylarsonate antibodies bearing a cross-reactive idiotype. Immunochemistry (1976) 1.09

Structural studies on induced antibodies with defined idiotypic specificities. VII. The complete amino acid sequence of the heavy chain variable region of anti-p-azophenylarsenate antibodies from A/J mice bearing a cross-reactive idiotype. J Immunol (1979) 1.08

Isolation and characterization of a bacteriochlorophyll-containing protein from Rhodopseudomonas spheroides. J Biol Chem (1972) 1.08

Genetic and serological analysis of the expression of crossreactive idiotypic determinants on anti-p-azobenzenarsonate antibodies and p-azobenzenarsonate-specific suppressor T cell factors. Proc Natl Acad Sci U S A (1981) 1.07

The effect of restricted dietary intake on the antibody mediated response of the zinc deficient A/J mouse. J Nutr (1978) 1.07

Properties of a minor cross-reactive idiotype associated with anti-p-azophenylarsonate antibodies of A/J mice. J Immunol (1981) 1.07

Regeneration of T-cell helper function in zinc-deficient adult mice. Proc Natl Acad Sci U S A (1978) 1.06

Structural studies on induced antibodies with defined idiotypic specificities--VIII. NH2-terminal amino acid sequence analysis of the heavy and light chain variable regions of monoclonal anti-para-azophenylarsonate antibodies from A/J mice differing with respect to a cross-reactive idiotype. Mol Immunol (1979) 1.06

Immunological activity of cytochrome c. II. Localization of a major antigenic determinant of human cytochrome c. J Biol Chem (1970) 1.05

In nature of idiotypes associated with anti-p-azophenylarsonate antibodies in A/J mice. Ann Immunol (Paris) (1979) 1.04

Antigen and receptor-driven regulatory mechanisms. VI. Demonstration of cross-reactive idiotypic determinants on azobenzenearsonate-specific antigen-binding suppressor T cells producing soluble suppressor factor(s). J Immunol (1980) 1.03

Biosynthesis of antibody molecules with similar properties during prolonged immunization. Biochemistry (1969) 1.02

Antibodies against cytochromes c from vertebrates. J Biol Chem (1966) 1.02

Glucocorticoids and irradiation-induced apoptosis in normal murine bone marrow B-lineage lymphocytes as determined by flow cytometry. Immunology (1993) 1.02

Analysis of the cellular basis of idiotype-specific suppression. J Immunol (1978) 1.01

Reversible dissociation of fragment Fc of rabbit gamma-G-immunoglobulin. J Biol Chem (1966) 1.00

Presence of highly conserved idiotypic determinants in a family of antibodies that constitute an intrastrain cross-reactive idiotype. J Exp Med (1980) 0.99

Structural studies on induced antibodies with defined idiotypic specificities. V. The complete amino acid sequence of the light chain variable regions of anti-p-azophenylarsonate antibodies from A/J mice bearing a cross-reactive idiotype. J Immunol (1977) 0.99

Structural studies on induced antibodies with defined idiotypic specificities. II. The light chains of anti-p-azophenylarsonate antibodies from A/J mice bearing a cross-reactive idiotype. J Immunol (1975) 0.99

Individual antigenic specificity in immunoglobulins: relationship to biosynthesis. Fed Proc (1972) 0.99

Induction of high titers of anti-IgE by immunization of inbred mice with syngeneic IgE. Proc Natl Acad Sci U S A (1987) 0.98

Effect of idiotype-specific suppressor T cells on primary and secondary responses. J Exp Med (1978) 0.98

Functional capacity of the residual lymphocytes from zinc-deficient adult mice. Br J Nutr (1993) 0.97

Monoclonal ant-idiotypic antibodies reactive with a highly conserved determinant on A/J serum anti-para-azophenylarsonate antibodies. J Exp Med (1981) 0.96

Biologic activity of an idiotype-bearing suppressor T cell factor produced by a long-term T cell hybridoma. J Immunol (1982) 0.96

The fate of chymopapain injected for therapy of intervertebral disc disease. J Lab Clin Med (1974) 0.95

Identity of the V kappa 10-Ars-A gene segments of the A/J and BALB/c strains. Proc Natl Acad Sci U S A (1987) 0.95

Dominance of an immune response by secondary cells: quantitation by allotype analysis. J Immunol (1980) 0.94

Immunofluorescent evidence for cellular control of synthesis of variable regions of light and heavy chains of immunoglobulins G and M by the same gene. Proc Natl Acad Sci U S A (1971) 0.94

Preferential induction of apoptosis in mouse CD4+CD8+ alpha beta TCRloCD3 epsilon lo thymocytes by zinc. J Cell Physiol (1995) 0.93

Degree of heterogeneity of binding specificities of antibodies to the phenylarsonate group that share a common idiotype. Mol Immunol (1982) 0.92

Antibodies to rabbit cytochrome c arising in rabbits. Science (1967) 0.92

Suppression of immunological memory for a cross-reactive idiotype in adult mice. Eur J Immunol (1974) 0.91

General method for isolation and recovery of B cells bearing specific receptors. J Exp Med (1974) 0.91