Published in Prostaglandins on September 01, 1973
Production of collagenase and prostaglandins by isolated adherent rheumatoid synovial cells. Proc Natl Acad Sci U S A (1976) 5.40
Acetylation of prostaglandin synthase by aspirin. Proc Natl Acad Sci U S A (1975) 4.92
Prostaglandin endoperoxides. A new concept concerning the mode of action and release of prostaglandins. Proc Natl Acad Sci U S A (1974) 4.10
Prostaglandin production by rheumatoid synovial cells: stimulation by a factor from human mononuclear Cells. J Exp Med (1977) 2.47
Thromboxane A2 mediates augmented polymorphonuclear leukocyte adhesiveness. J Clin Invest (1980) 1.48
A comparison of the abilities of acetylsalicylic acid, flurbiprofen and indomethacin to inhibit the release reaction and prostaglandin synthesis in human blood platelets. Br J Pharmacol (1979) 1.34
Prostaglandin synthesis in isolated rat kidney glomeruli. Proc Natl Acad Sci U S A (1979) 1.06
Estimation and characterization of prostaglandins in the human gastrointestinal tract. Br J Pharmacol (1977) 1.05
Prostaglandins: Their role in egg-laying of the cricket Teleogryllus commodus. Proc Natl Acad Sci U S A (1981) 1.05
Stimulation of the antigen-induced contraction of guinea-pig trachea and immunological release of histamine and SRS-A from sensitized guinea-pig lung by (2-isopropyl-3-indolyl)-3 pyridyl ketone (L8027) and indomethacin. Br J Pharmacol (1980) 1.00
The influence of metyrapone on the synthesis and release of prostaglandins from the pregnant rat uterus in vitro. Br J Pharmacol (1975) 0.95
Multicentre trial of naproxen and phenylbutazone in acute gout. Ann Rheum Dis (1977) 0.94
Biosynthesis of prostaglandins in rabbit kidney medulla. Properties of prostaglandin synthase. Biochem J (1976) 0.90
Angiotensin receptors in bovine umbilical artery and their inhibition by nonsteroidal anti-inflammatory drugs. Br J Pharmacol (1981) 0.85
Arachidonic acid metabolism and modulation of in vitro anaphylaxis by 5,8,11,14-eicosatetraynoic acid and 9a,12a-octadecadiynoic acid. Br J Pharmacol (1981) 0.84
Pharmacology of benzydamine. Inflammopharmacology (1998) 0.81
Renal prostaglandin synthesis in the spontaneously hypertensive rat. J Clin Invest (1976) 0.81
An ion selective electrode for the determination of calcium activity [proceedings]. J Physiol (1978) 0.80
Effect of nicotine on the formation of prostacyclin-like activity and thromboxane in rabbit aorta and platelets. Br J Pharmacol (1984) 0.80
Malondialdehyde production and the release reaction in rat blood platelets: inhibition by aspirin and indomethacin ex vivo [proceedings]. Br J Pharmacol (1976) 0.79
Aspirin, protein transacetylation and inhibition of prostaglandin synthetase in the kidney. Br J Pharmacol (1978) 0.79
Contribution to the pathogenesis of dysmenorrhea. Arch Gynecol (1984) 0.78
Mechanism of prostaglandin biosynthesis in rabbit kidney medulla. A rate-limiting step and the differential stimulatory actions of L-adrenaline and glutathione. Biochem J (1976) 0.78
Potential therapeutic applications of aspirin and other cyclo-oxygenase inhibitors. Br J Clin Pharmacol (1980) 0.77
Prostaglandin formation from exogenous precursor in homogenates of human cardiac tissue. Basic Res Cardiol (1984) 0.75
Effect of α-tocopheryl succinate on the molecular damage induced by indomethacin in C6 glioma cells. Exp Ther Med (2014) 0.75
Purification and characterization of sheep platelet cyclo-oxygenase. Acetylation by aspirin prevents haemin binding to the enzyme. Biochem J (1986) 0.75
Drugs which inhibit prostaglandin biosynthesis. Pharmacol Rev (1974) 7.76
Design of specific inhibitors of angiotensin-converting enzyme: new class of orally active antihypertensive agents. Science (1977) 5.39
Spectrophotometric assay and properties of the angiotensin-converting enzyme of rabbit lung. Biochem Pharmacol (1971) 5.33
Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase. Proc Natl Acad Sci U S A (1993) 4.82
Arterial walls are protected against deposition of platelet thrombi by a substance (prostaglandin X) which they make from prostaglandin endoperoxides. Prostaglandins (1976) 4.44
Anti-inflammatory steroids induce biosynthesis of a phospholipase A2 inhibitor which prevents prostaglandin generation. Nature (1979) 4.41
Macrocortin: a polypeptide causing the anti-phospholipase effect of glucocorticoids. Nature (1980) 4.29
The importance of phospholipase-A2 in prostaglandin biosynthesis. Biochem Pharmacol (1976) 3.88
Inhibition of prostaglandin synthetase in brain explains the anti-pyretic activity of paracetamol (4-acetamidophenol). Nature (1972) 3.30
A new approach to anti-inflammatory drugs. Biochem Pharmacol (1979) 2.95
Phospholipase A2 activity of guinea-pig isolated perfused lungs: stimulation, and inhibition by anti-inflammatory steroids. Br J Pharmacol (1978) 2.41
Design of potent competitive inhibitors of angiotensin-converting enzyme. Carboxyalkanoyl and mercaptoalkanoyl amino acids. Biochemistry (1977) 2.17
Role of resident peritoneal macrophages and mast cells in chemokine production and neutrophil migration in acute inflammation: evidence for an inhibitory loop involving endogenous IL-10. J Immunol (1999) 1.99
Mobilizing lipocortin 1 in adherent human leukocytes downregulates their transmigration. Nat Med (1996) 1.96
Anti-phospholipase proteins. Prostaglandins (1984) 1.93
Human breast lesions: characterization with contrast-enhanced in vivo proton MR spectroscopy--initial results. Radiology (2001) 1.92
Enzymes of the renin-angiotensin system and their inhibitors. Annu Rev Biochem (1982) 1.91
Anti-inflammatory lipocortin 1 production by peripheral blood leucocytes in response to hydrocortisone. Lancet (1990) 1.88
The distribution and metabolism of arachidonic acid in rabbit platelets during aggregation and its modification by drugs. Br J Pharmacol (1977) 1.87
Human recombinant lipocortin 1 has acute local anti-inflammatory properties in the rat paw edema test. Proc Natl Acad Sci U S A (1989) 1.82
Glucocorticoids induce the formation and release of anti-inflammatory and anti-phospholipase proteins into the peritoneal cavity of the rat. Br J Pharmacol (1982) 1.74
Inflammatory effects of prostaglandin D2 in rat and human skin. Br J Pharmacol (1976) 1.69
New insight into deformation-dependent hydraulic permeability of gels and cartilage, and dynamic behavior of agarose gels in confined compression. J Biomech (2003) 1.67
The electronic aggregometer: a novel device for assessing platelet behavior in blood. J Pharmacol Methods (1980) 1.66
Partial purification of rabbit aorta contracting substance-releasing factor and inhibition of its activity by anti-inflammatory steroids. Nature (1976) 1.65
Inhibition of phospholipase. Br Med Bull (1983) 1.65
Recombinant human lipocortin 1 inhibits thromboxane release from guinea-pig isolated perfused lung. Nature (1987) 1.63
Promoting detachment of neutrophils adherent to murine postcapillary venules to control inflammation: effect of lipocortin 1. Proc Natl Acad Sci U S A (1998) 1.60
Glucocorticoids act within minutes to inhibit recruitment of signalling factors to activated EGF receptors through a receptor-dependent, transcription-independent mechanism. Br J Pharmacol (2000) 1.57
Synthesis of 6-keto-PGF1alpha by ram seminal vesicle microsomes. Prostaglandins (1977) 1.57
Modulation of IL-1-induced neutrophil migration by dexamethasone and lipocortin 1. J Immunol (1993) 1.57
Binding of peptide substrates and inhibitors of angiotensin-converting enzyme. Importance of the COOH-terminal dipeptide sequence. J Biol Chem (1980) 1.55
Concentrations of angiotensin-converting enzyme in tissues of the rat. Biochim Biophys Acta (1971) 1.50
Inhibition of neutrophil and monocyte recruitment by endogenous and exogenous lipocortin 1. Br J Pharmacol (1997) 1.50
"Milwaukee shoulder"--association of microspheroids containing hydroxyapatite crystals, active collagenase, and neutral protease with rotator cuff defects. II. Synovial fluid studies. Arthritis Rheum (1981) 1.50
Endogenous monocyte chemoattractant protein-1 recruits monocytes in the zymosan peritonitis model. J Leukoc Biol (1998) 1.49
Rapid reduction of prostaglandin 15-hydroxy dehydrogenase activity in rat tissues after treatment with protein synthesis inhibitors. Br J Pharmacol (1975) 1.48
Inhibition of poly (ADP-ribose) synthetase attenuates neutrophil recruitment and exerts antiinflammatory effects. J Exp Med (1997) 1.47
Annexin-A1: a pivotal regulator of the innate and adaptive immune systems. Br J Pharmacol (2008) 1.43
Genetic hypertension in rats is accompanied by a defect in renal prostaglandin catabolism. Nature (1976) 1.41
Release of collagenase, neutral protease, and prostaglandins from cultured mammalian synovial cells by hydroxyapatite and calcium pyrophosphate dihydrate crystals. Arthritis Rheum (1981) 1.40
Lipocortin-1 fragments inhibit neutrophil accumulation and neutrophil-dependent edema in the mouse. A qualitative comparison with an anti-CD11b monoclonal antibody. J Immunol (1993) 1.40
1-phenyl-3-pyrazolidone: an inhibitor of cyclo-oxygenase and lipoxygenase pathways in lung and platelets. Prostaglandins (1978) 1.39
Further studies on the enzymatic conversion of prostaglandin endoperoxide into prostacyclin by porcine aorta microsomes. Biochim Biophys Acta (1978) 1.37
Neutrophil interaction with inflamed postcapillary venule endothelium alters annexin 1 expression. Am J Pathol (2001) 1.37
The inhibition by hydrocortisone of prostaglandin biosynthesis in rat peritoneal leucocytes is correlated with intracellular macrocortin levels. Br J Pharmacol (1981) 1.34
Inhibition of prostaglandin biosynthesis. Biochem Pharmacol (1974) 1.34
Lipocortin 1 mediates dexamethasone-induced growth arrest of the A549 lung adenocarcinoma cell line. Proc Natl Acad Sci U S A (1992) 1.34
Synovial origins of Rice bodies in joint fluid. Arthritis Rheum (1980) 1.31
"Milwaukee shoulder"--association of microspheroids containing hydroxyapatite crystals, active collagenase, ad neutral protease with rotator cuff defects. III. Morphologic and biochemical studies of an excised synovium showing chondromatosis. Arthritis Rheum (1981) 1.31
A comparison of the acute inflammatory response in adrenalectomised and sham-operated rats. Br J Pharmacol (1986) 1.31
Leukocyte transmigration, but not rolling or adhesion, is selectively inhibited by dexamethasone in the hamster post-capillary venule. Involvement of endogenous lipocortin 1. J Immunol (1995) 1.30
The ferroprotein component of a methylene hydroxylase. Biochem Biophys Res Commun (1967) 1.30
Inhibition of homogeneous angiotensin-converting enzyme of rabbit lung by synthetic venom peptides of Bothrops jararaca. Biochim Biophys Acta (1973) 1.29
Relationship between the anti-phospholipase and anti-inflammatory effects of glucocorticoid-induced proteins. Eur J Pharmacol (1984) 1.28
Human recombinant lipocortin 1 inhibits prostacyclin production by human umbilical artery in vitro. Prostaglandins (1987) 1.28
Hydrocortisone and 'macrocortin' inhibit the zymosan-induced release of lyso-PAF from rat peritoneal leucocytes. Life Sci (1985) 1.27
Arachidonic acid 15-lipoxygenase from rabbit peritoneal polymorphonuclear leukocytes. Partial purification and properties. J Biol Chem (1981) 1.25
Lipocortin 1 mediates the inhibition by dexamethasone of the induction by endotoxin of nitric oxide synthase in the rat. Proc Natl Acad Sci U S A (1995) 1.24
Dual metalloprotease inhibitors: mercaptoacetyl-based fused heterocyclic dipeptide mimetics as inhibitors of angiotensin-converting enzyme and neutral endopeptidase. J Med Chem (1997) 1.24
Post-translational modification plays an essential role in the translocation of annexin A1 from the cytoplasm to the cell surface. FASEB J (2006) 1.21
Effects of modulators of arachidonic acid metabolism on the synthesis and release of slow-reacting substance of anaphylaxis. Br J Pharmacol (1979) 1.21
Milwaukee Shoulder syndrome: eleven additional cases with involvement of the knee in seven (basic calcium phosphate crystal deposition disease). Semin Arthritis Rheum (1984) 1.21
Crystal-induced endogenous pyrogen production. A further look at gouty inflammation. Arthritis Rheum (1985) 1.20
POMC gene-derived peptides activate melanocortin type 3 receptor on murine macrophages, suppress cytokine release, and inhibit neutrophil migration in acute experimental inflammation. J Immunol (1999) 1.20
Human annexin 1 is highly expressed during the differentiation of the epithelial cell line A 549: involvement of nuclear factor interleukin 6 in phorbol ester induction of annexin 1. Cell Growth Differ (1998) 1.20
Glucocorticoid-and non-glucocorticoid induction of lipocortins (annexins) 1 and 2 in rat peritoneal leucocytes in vivo. Br J Pharmacol (1993) 1.19
Choledocholithiasis: comparison of MR cholangiography and endoscopic retrograde cholangiography. Radiology (1996) 1.19
Annexin I is stored within gelatinase granules of human neutrophil and mobilized on the cell surface upon adhesion but not phagocytosis. Cell Biol Int (2000) 1.17
The assay of endogenous cholecystokinin and factors influencing its release in the dog and cat. Gastroenterology (1971) 1.17
Annexin 1 peptides protect against experimental myocardial ischemia-reperfusion: analysis of their mechanism of action. FASEB J (2001) 1.16
p53 down-regulates human matrix metalloproteinase-1 (Collagenase-1) gene expression. J Biol Chem (1999) 1.15
Identification of several species of phospholipase inhibitory protein(s) by radioimmunoassay for lipomodulin. Biochem Biophys Res Commun (1982) 1.15
Role of lipocortin-1 in the anti-hyperalgesic actions of dexamethasone. Br J Pharmacol (1997) 1.15
Detection of lipocortin 1 in human lung lavage fluid: lipocortin degradation as a possible proteolytic mechanism in the control of inflammatory mediators and inflammation. Environ Health Perspect (1990) 1.14
IL-6 stimulates annexin 1 expression and translocation and suggests a new biological role as class II acute phase protein. Cytokine (1998) 1.14
Design of angiotensin converting enzyme inhibitors. Nat Med (1999) 1.12
Mitogenic effects of hydroxyapatite and calcium pyrophosphate dihydrate crystals on cultured mammalian cells. Arthritis Rheum (1984) 1.11
Measurement of lipocortin 1 levels in murine peripheral blood leukocytes by flow cytometry: modulation by glucocorticoids and inflammation. Br J Pharmacol (1996) 1.11
Design of potent and specific inhibitors of carboxypeptidases A and B. Biochemistry (1979) 1.11
Lipocortin-1 and the control of arachidonic acid release in cell signalling. Glucocorticoids (changed from glucorticoids) inhibit G protein-dependent activation of cPLA2 activity. Biochem Pharmacol (1995) 1.10
Extraction and thin-layer chromatography of arachidonic acid metabolites. Methods Enzymol (1982) 1.10
Hamartoma of the breast: a clinicopathological review. J Clin Pathol (2002) 1.10
Transforming growth factor beta 1 stimulates inorganic pyrophosphate elaboration by porcine cartilage. Arthritis Rheum (1991) 1.10
Lipocortin 1 protects against splanchnic artery occlusion and reperfusion injury by affecting neutrophil migration. J Immunol (1997) 1.09
Bone resorption stimulated by elevated serum 1,25-(OH)2-vitamin D concentrations in healthy men. Kidney Int (1983) 1.08
Lipocortin 1 and the control of cPLA2 activity in A549 cells. Glucocorticoids block EGF stimulation of cPLA2 phosphorylation. Biochem Pharmacol (1996) 1.08
Further characterization of the glucocorticoid-induced antiphospholipase protein "renocortin". Biochem Biophys Res Commun (1983) 1.08
Neutrophil accumulation induced by bacterial lipopolysaccharide: effects of dexamethasone and annexin 1. Clin Exp Immunol (2001) 1.07
Factors influencing the turnover of prostaglandin synthetase. Br J Pharmacol (1975) 1.07
Origin and significance of rice bodies in synovial fluid. Lancet (1982) 1.06
Release of pyrophosphate by normal mammalian articular hyaline and fibrocartilage in organ culture. Arthritis Rheum (1981) 1.06
Molecular determinants of monosodium urate crystal-induced murine peritonitis: a role for endogenous mast cells and a distinct requirement for endothelial-derived selectins. J Pharmacol Exp Ther (1997) 1.05
Calcification in breast lesions: pathologists' perspective. J Clin Pathol (2007) 1.05