Published in Nature on March 22, 1974
Complement and immunoglobulins stimulate superoxide production by human leukocytes independently of phagocytosis. J Clin Invest (1975) 6.25
Subcellular localization of the b-cytochrome component of the human neutrophil microbicidal oxidase: translocation during activation. J Cell Biol (1983) 5.73
Secretion of plasminogen activator by human polymorphonuclear leukocytes. Modulation by glucocorticoids and other effectors. J Exp Med (1977) 2.60
Concanavalin A induces microtubule assembly and specific granule discharge in human polymorphonuclear leukocytes. J Cell Biol (1976) 2.08
Effects of phorbol myristate acetate on the metabolism and ultrastructure of neutrophils in chronic granulomatous disease. J Clin Invest (1974) 1.92
Phorbol myristate acetate stimulates pinocytosis and membrane spreading in mouse peritoneal macrophages. J Cell Biol (1980) 1.88
Mechanisms of lysosomal enzyme release from human polymorphonuclear leukocytes. Effects of phorbol myristate acetate. J Cell Biol (1975) 1.87
Intracellular and extracellular degranulation of human polymorphonuclear azurophil and specific granules induced by immune complexes. Infect Immun (1974) 1.73
The differential mobilization of human neutrophil granules. Effects of phorbol myristate acetate and ionophore A23187. Am J Pathol (1977) 1.60
T lymphocyte recruitment by interleukin-8 (IL-8). IL-8-induced degranulation of neutrophils releases potent chemoattractants for human T lymphocytes both in vitro and in vivo. J Clin Invest (1996) 1.53
The giant organelles in beige and Chediak-Higashi fibroblasts are derived from late endosomes and mature lysosomes. J Exp Med (1993) 1.50
Phagocytosing human neutrophils inactivate their own granular enzymes. J Clin Invest (1981) 1.42
Fate of human lactoferrin and myeloperoxidase in phagocytizing human neutrophils: effects of immunoglobulin G subclasses and immune complexes coated on latex beads. Infect Immun (1975) 1.42
Degranulating stimuli decrease the neagative surface charge and increase the adhesiveness of human neutrophils. J Clin Invest (1980) 1.41
The lytic granules of natural killer cells are dual-function organelles combining secretory and pre-lysosomal compartments. J Cell Biol (1990) 1.39
Inflammatory mediators in dengue virus infection in children: interleukin-8 and its relationship to neutrophil degranulation. Infect Immun (2000) 1.30
Fluoride-mediated activation of the respiratory burst in human neutrophils. A reversible process. J Clin Invest (1979) 1.23
Effect of N-acetylcysteine on the pulmonary response to endotoxin in the awake sheep and upon in vitro granulocyte function. J Clin Invest (1984) 1.21
Human neutrophil plasminogen activator is localized in specific granules and is translocated to the cell surface by exocytosis. J Exp Med (1986) 1.13
Role of Ca2+ and Mg2+ in some human neutrophil functions as indicated by ionophore A23187. Infect Immun (1976) 1.11
Calcium movement and membrane potential changes in the early phase of neutrophil activation by phorbol myristate acetate: a study with ion-selective electrodes. J Cell Biol (1982) 1.09
Cytolytic effects of neutrophils: role for a membrane-bound neutral proteinase. Proc Natl Acad Sci U S A (1986) 1.03
Stimulus specificity of prostaglandin inhibition of rabbit polymorphonuclear leukocyte lysosomal enzyme release and superoxide anion production. Am J Pathol (1984) 1.02
Up-regulation of human neutrophil receptors for Neisseria gonorrhoeae expressing PII outer membrane proteins. Infect Immun (1990) 1.01
Administration of C1 inhibitor reduces neutrophil activation in patients with sepsis. Clin Diagn Lab Immunol (2003) 1.00
Neutrophilic granulocytes in acute bacterial infection. Sequential studies on lysozyme, myeloperoxidase and lactoferrin. Clin Exp Immunol (1976) 0.97
Bactericidal capacity of phorbol myristate acetate-treated human polymorphonuclear leukocytes. Infect Immun (1978) 0.92
Rat neutrophil activation and effects of lipoxygenase and cyclooxygenase inhibitors. Am J Pathol (1984) 0.90
Ultrastructural localization of lactoferrin and iron-binding protein in human neutrophils and rabbit heterophils. Am J Pathol (1982) 0.90
Phorbol esters induce synthesis of thromboplastin activity in human monocytes. Biochem J (1981) 0.87
Granulophysin is located in the membrane of azurophilic granules in human neutrophils and mobilizes to the plasma membrane following cell stimulation. Am J Pathol (1994) 0.86
Activation of monocyte and granulocyte antibody-dependent cytotoxicity by phorbol myristate acetate. Infect Immun (1982) 0.84
Effect of phorbol myristate acetate on cellular metabolism and lysozyme release from alveolar macrophages and polymorphonuclear leukocytes. Infect Immun (1978) 0.84
Effects of antimycin A and 2-deoxyglucose on secretion in human platelets. Differential inhibition of the secretion of acid hydrolases and adenine nucleotides. Biochem J (1979) 0.83
Protein and glycoprotein electrophoretic patterns of enriched fractions of primary and secondary granules from guinea pig polymorphonuclear leukocytes. J Cell Biol (1975) 0.83
Natural inhibitor from Candida albicans blocks release of azurophil and specific granule contents by chemotactic peptide-stimulated human neutrophils. Infect Immun (1989) 0.82
Fine structural alterations induced in erythocytes by phorbol myristate acetate. Am J Pathol (1978) 0.81
Divergent effects of co-carcinogenic phorbol esters and a synthetic diacylglycerol on human neutrophil chemokinesis and granular enzyme secretion. Br J Pharmacol (1987) 0.80
Release of enzymes from human leucocytes during incubation with Neisseria gonorrhoeae. Br J Vener Dis (1977) 0.79
Regulation of inflammation-primed activation of macrophages by two serum factors, vitamin D3-binding protein and albumin. Infect Immun (1993) 0.79
A Critical Reappraisal of Neutrophil Extracellular Traps and NETosis Mimics Based on Differential Requirements for Protein Citrullination. Front Immunol (2016) 0.78
The energetics of Na-dependent solute transport in isolated cells [proceedings]. J Physiol (1978) 0.75
The embryonic cell lineage of the nematode Caenorhabditis elegans. Dev Biol (1983) 21.29
In vitro bactericidal capacity of human polymorphonuclear leukocytes: diminished activity in chronic granulomatous disease of childhood. J Clin Invest (1967) 10.26
Studies of the metabolic activity of leukocytes from patients with a genetic abnormality of phagocytic function. J Clin Invest (1967) 9.01
The neural circuit for touch sensitivity in Caenorhabditis elegans. J Neurosci (1985) 7.13
Electron microscopical reconstruction of the anterior sensory anatomy of the nematode Caenorhabditis elegans.?2UU. J Comp Neurol (1975) 6.58
Occurrence of multiple genomovars of Burkholderia cepacia in cystic fibrosis patients and proposal of Burkholderia multivorans sp. nov. Int J Syst Bacteriol (1997) 5.60
Complement (C5-a)-induced granulocyte aggregation in vitro. A possible mechanism of complement-mediated leukostasis and leukopenia. J Clin Invest (1977) 5.16
Fine structural alterations induced in platelets by adenosine diphosphate. Blood (1968) 4.95
Cortical flow in animal cells. Science (1988) 4.66
Strains of Pseudomonas putrefaciens from clinical material. J Clin Pathol (1975) 4.66
An evaluation of confocal versus conventional imaging of biological structures by fluorescence light microscopy. J Cell Biol (1987) 4.59
Multiphoton excitation provides optical sections from deeper within scattering specimens than confocal imaging. Biophys J (1998) 4.44
On the control of germ cell development in Caenorhabditis elegans. Dev Biol (1981) 4.28
Determination of cell division axes in the early embryogenesis of Caenorhabditis elegans. J Cell Biol (1987) 4.20
Fatal granulomatous disease of childhood. An inborn abnormality of phagocytic function. Lancet (1966) 3.97
The structure of the ventral nerve cord of Caenorhabditis elegans. Philos Trans R Soc Lond B Biol Sci (1976) 3.94
Regulation and cell autonomy during postembryonic development of Caenorhabditis elegans. Dev Biol (1980) 3.88
Kluyvera, a new (redefined) genus in the family Enterobacteriaceae: identification of Kluyvera ascorbata sp. nov. and Kluyvera cryocrescens sp. nov. in clinical specimens. J Clin Microbiol (1981) 3.63
Familial dyserythropoietic anaemia and thrombocytopenia due to an inherited mutation in GATA1. Nat Genet (2000) 3.50
Long-term two-photon fluorescence imaging of mammalian embryos without compromising viability. Nat Biotechnol (1999) 3.44
Protection of phagocytized bacteria from the killing action of antibiotics. Nature (1966) 3.12
Strains of Achromobacter xylosoxidans from clinical material. J Clin Pathol (1977) 3.04
Platelet interaction with bacteria. I. Reaction phases and effects of inhibitors. Am J Pathol (1971) 3.04
The C. elegans zyg-1 gene encodes a regulator of centrosome duplication with distinct maternal and paternal roles in the embryo. Cell (2001) 2.92
Identification of Enterobacteriaceae by the API 20E system. J Clin Pathol (1978) 2.84
Completion of cytokinesis in C. elegans requires a brefeldin A-sensitive membrane accumulation at the cleavage furrow apex. Curr Biol (2001) 2.64
On the mechanisms of cytokinesis in animal cells. J Theor Biol (1983) 2.63
Identification and population structure of Burkholderia stabilis sp. nov. (formerly Burkholderia cepacia genomovar IV). J Clin Microbiol (2000) 2.63
Cortical and cytoplasmic flow polarity in early embryonic cells of Caenorhabditis elegans. J Cell Biol (1993) 2.54
The dynactin complex is required for cleavage plane specification in early Caenorhabditis elegans embryos. Curr Biol (1998) 2.53
A newly defined X-linked trait in man with demonstration of the Lyon effect in carrier females. Lancet (1967) 2.47
Cyclic GMP and cell movement. Nature (1973) 2.46
Abnormal adherence of sickle erythrocytes to cultured vascular endothelium: possible mechanism for microvascular occlusion in sickle cell disease. J Clin Invest (1980) 2.34
Interaction of membrane systems in blood platelets. Am J Pathol (1972) 2.32
Selective labilization of specific granules in polymorphonuclear leukocytes by phorbol myristate acetate. Am J Pathol (1974) 2.27
An ultrastructural basis for the shape changes induced in platelets by chilling. Blood (1967) 2.20
Meningitis caused by Pseudomonas paucimobilis. J Clin Pathol (1979) 2.18
The systems approach to diagnostic microbiology. Crit Rev Microbiol (1981) 2.15
The ultrastructural localization and release of platelet lipids. Blood (1966) 2.10
A probability matrix for the identification of gram-negative, aerobic, non-fermentative bacteria that grow on nutrient agar. J Gen Microbiol (1986) 2.07
Dynamics and ultrastructure of developmental cell fusions in the Caenorhabditis elegans hypodermis. Curr Biol (1998) 2.04
Cytochalasin B. IV. Inhibition and stimulation of chemotaxis of rabbit and human polymorphonuclear leukocytes. J Immunol (1972) 2.04
Biochemical studies of two patients with the gray platelet syndrome. Selective deficiency of platelet alpha granules. J Clin Invest (1980) 2.01
Corticosteroids inhibit complement-induced granulocyte aggregation. A possible mechanism for their efficacy in shock states. J Clin Invest (1979) 2.01
Activation of flavin-containing oxidases underlies light-induced production of H2O2 in mammalian cells. Proc Natl Acad Sci U S A (1999) 2.00
Mitogenic properties of a calcium ionophore, A23187. Proc Natl Acad Sci U S A (1974) 1.98
The Chediak-Higashi syndrome: a possible lysosomal disease. Blood (1966) 1.94
The influence of phorbol myristate acetate on oxygen consumption by polymorphonuclear leukocytes. J Lab Clin Med (1974) 1.92
Effects of phorbol myristate acetate on the metabolism and ultrastructure of neutrophils in chronic granulomatous disease. J Clin Invest (1974) 1.92
Replication occurs at discrete foci spaced throughout nuclei replicating in vitro. J Cell Sci (1989) 1.84
A revised probability matrix for the identification of gram-negative, aerobic, rod-shaped, fermentative bacteria. J Gen Microbiol (1986) 1.81
Nonmuscle myosin heavy chain IIA mutations define a spectrum of autosomal dominant macrothrombocytopenias: May-Hegglin anomaly and Fechtner, Sebastian, Epstein, and Alport-like syndromes. Am J Hum Genet (2001) 1.80
Modulation of human neutrophil chemotactic responses by cyclic 3',5'-guanosine monophosphate and cyclic 3',5'-adenosine monophosphate. Metabolism (1975) 1.78
MinK-related peptide 1: A beta subunit for the HCN ion channel subunit family enhances expression and speeds activation. Circ Res (2001) 1.78
Effect of inoculum size on the phenotypic characterization of Campylobacter species. J Clin Microbiol (1991) 1.75
Effect of a short course of prednisone in the prevention of early relapse after the emergency room treatment of acute asthma. N Engl J Med (1991) 1.74
Influence of cytochalasin B on the shape change induced in platelets by cold. Blood (1973) 1.72
Platelet interaction with bacteria. II. Fate of the bacteria. Am J Pathol (1971) 1.71
Carbapenemases of Chryseobacterium (Flavobacterium) meningosepticum: distribution of blaB and characterization of a novel metallo-beta-lactamase gene, blaB3, in the type strain, NCTC 10016. Antimicrob Agents Chemother (2000) 1.68
Connectivity changes in a class of motoneurone during the development of a nematode. Nature (1978) 1.65
Uptake of latex particles by blood platelets: phagocytosis or sequestration? Am J Pathol (1972) 1.65
How the confocal laser scanning microscope entered biological research. Biol Cell (2003) 1.64
Flunarizine. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic use. Drugs (1984) 1.64
Effects of colchicine and vinca alkaloids on human platelets. 3. Influence on primary internal contraction and secondary aggregation. Am J Pathol (1969) 1.63
Test reproducibility of the API (20E), Enterotube, and Pathotec systems. J Clin Pathol (1977) 1.63
Effects of the lonophore A23187 on blood platelets I. Influence on aggregation and secretion. Am J Pathol (1974) 1.59
Polyploid tissues in the nematode Caenorhabditis elegans. Dev Biol (1985) 1.59
Cell fusions in the developing epithelial of C. elegans. Dev Biol (1994) 1.58
Formation of the vulva in Caenorhabditis elegans: a paradigm for organogenesis. Development (1999) 1.57
Four-dimensional imaging: the exploration of space and time. Trends Biotechnol (1998) 1.57
Norfloxacin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use. Drugs (1985) 1.56
Reliability of absent platelet dense bodies as a diagnostic criterion for Hermansky-Pudlak syndrome. Am J Hematol (1987) 1.56
Metabolism and function of human platelets washed by albumin density gradient separation. Br J Haematol (1977) 1.56
Pseudomonas paucimobilis from a leg ulcer on a Japanese seaman. J Clin Microbiol (1979) 1.55
A genetic screen for temperature-sensitive cell-division mutants of Caenorhabditis elegans. Genetics (1998) 1.55
Reproducibility of tolerance tests that are useful in the identification of campylobacteria. J Clin Microbiol (1991) 1.54
Distribution in clinical material and identification of Pseudomonas maltophilia. J Clin Pathol (1979) 1.54
Dietary intake, eating behavior, and physical activity-related determinants of high body mass index in rural communities in Wyoming, Montana, and Idaho. Int J Obes Relat Metab Disord (2003) 1.54
Effects of colchicine and Vinca alkaloids on human platelets. I. Influence on platelet microtubules and contractile function. Am J Pathol (1968) 1.53
The fine structure of sickled hemoglobin in situ. Blood (1968) 1.51
Cell cycling and DNA replication in a mutant blocked in cell division in the nematode Caenorhabditis elegans. Dev Biol (1978) 1.50
The transfer of thorium particles from plasma to platelets and platelet granules. Am J Pathol (1968) 1.47
A search for the platelet secretory pathway using electron dense tracers. Am J Pathol (1970) 1.47
The C. elegans septin genes, unc-59 and unc-61, are required for normal postembryonic cytokineses and morphogenesis but have no essential function in embryogenesis. J Cell Sci (2000) 1.46
A review of numerical methods in bacterial identification. Antonie Van Leeuwenhoek (1980) 1.45
Ultrastructural studies of the gray platelet syndrome. Am J Pathol (1979) 1.45
Fibrinogen is the receptor for the endogenous lectin of human platelets. Nature (1981) 1.45
Nabilone. A preliminary review of its pharmacological properties and therapeutic use. Drugs (1985) 1.44
The spd-2 gene is required for polarization of the anteroposterior axis and formation of the sperm asters in the Caenorhabditis elegans zygote. Dev Biol (2000) 1.44
Production of lymphotoxin and migration inhibitory factor by established human lymphocytic cell lines. J Immunol (1970) 1.43
Neonatal meningitis caused by Achromobacter xylosoxidans. J Clin Microbiol (1985) 1.42
The effect of lumbar belts on isolated lumbar muscle. Strength and dynamic capacity. Spine (Phila Pa 1976) (1995) 1.42
Cytochalasin B: microfilaments and "contractile" processes. Science (1971) 1.40
Localization of platelet prostaglandin production in the platelet dense tubular system. Am J Pathol (1976) 1.40
Can sustainable farming win the battle of the bottom line? Science (1993) 1.40
Proteomic analysis of platelet alpha-granules using mass spectrometry. J Thromb Haemost (2007) 1.40
Investigation of the release reaction in platelets exposed to phorbol myristate acetate. Am J Pathol (1974) 1.39