Published in Biochim Biophys Acta on June 06, 1979
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In vivo effects of alpha-DL-difluoromethylornithine on the metabolism and morphology of Trypanosoma brucei brucei. Mol Biochem Parasitol (1983) 1.69
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Purification of ornithine decarboxylase from kidneys of androgen-treated mice. Biochemistry (1982) 1.65
Quantitative intramuscular myoelectric activity of lumbar portions of psoas and the abdominal wall during a wide variety of tasks. Med Sci Sports Exerc (1998) 1.59
Changes in mouse kidney ornithine decarboxylase activity are brought about by changes in the amount of enzyme protein as measured by radioimmunoassay. J Biol Chem (1983) 1.55
Activity of temozolomide in the treatment of central nervous system tumor xenografts. Cancer Res (1995) 1.52
Mechanism of the irreversible inactivation of mouse ornithine decarboxylase by alpha-difluoromethylornithine. Characterization of sequences at the inhibitor and coenzyme binding sites. J Biol Chem (1992) 1.52
Purification and properties of O6-methylguanine-DNA transmethylase from rat liver. J Biol Chem (1983) 1.52
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Properties of spermidine N-acetyltransferase from livers of rats treated with carbon tetrachloride and its role in the conversion of spermidine into putrescine. J Biol Chem (1981) 1.48
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Stimulation of the decarboxylation of S-adenosylmethionine by putrescine in mammalian tissues. Biochem Biophys Res Commun (1968) 1.44
Effect of androgens on turnover of ornithine decarboxylase in mouse kidney. Studies using labeling of the enzyme by reaction with [14C] alpha-difluoromethylornithine. J Biol Chem (1982) 1.41
Pyridyloxobutyl adduct O6-[4-oxo-4-(3-pyridyl)butyl]guanine is present in 4-(acetoxymethylnitrosamino)-1-(3-pyridyl)-1-butanone-treated DNA and is a substrate for O6-alkylguanine-DNA alkyltransferase. Chem Res Toxicol (1997) 1.38
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O6-benzylguanine and its role in chemotherapy. Clin Cancer Res (1997) 1.36
Emetine resistance in Chinese hamster cells. Analysis of ribosomal proteins prepared from mutant cells. J Biol Chem (1979) 1.33
Too Fit To Fracture: exercise recommendations for individuals with osteoporosis or osteoporotic vertebral fracture. Osteoporos Int (2013) 1.33
Effect of 1,3-diaminopropane on ornithine decarboxylase enzyme protein in thioacetamide-treated rat liver. Biochem J (1983) 1.32
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The role of hypusine depletion in cytostasis induced by S-adenosyl-L-methionine decarboxylase inhibition: new evidence provided by 1-methylspermidine and 1,12-dimethylspermine. Biochem J (1994) 1.30
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Investigation of structure and rate of synthesis of ornithine decarboxylase protein in mouse kidney. Biochemistry (1984) 1.28
Paradoxical enhancement of S-adenosylmethionine decarboxylase in rat tissues following administration of the specific inhibitor methyl glyoxal bis(guanylhydrazone). Biochem Biophys Res Commun (1973) 1.27
Effects of aliphatic diamines on rat liver ornithine decarboxylase activity. Biochem J (1978) 1.27
Inhibition of spermidine formation in rat liver and kidney by methylglyoxal bis(guanylhydrazone). Biochem J (1973) 1.26
Crystal structure of the human O(6)-alkylguanine-DNA alkyltransferase. Nucleic Acids Res (2000) 1.25
Cytostasis induced in L1210 murine leukaemia cells by the S-adenosyl-L-methionine decarboxylase inhibitor 5'-([(Z)-4-amino-2-butenyl]methylamino)-5'-deoxyadenosine may be due to hypusine depletion. Biochem J (1992) 1.25
The upstream open reading frame of the mRNA encoding S-adenosylmethionine decarboxylase is a polyamine-responsive translational control element. J Biol Chem (1996) 1.24
Spontaneous excision of a large composite transposable element of Drosophila melanogaster. Nature (1985) 1.23
Binding of radioactive alpha-difluoromethylornithine to rat liver ornithine decarboxylase. Biochem Biophys Res Commun (1981) 1.23
Ornithine decarboxylase as an enzyme target for therapy. Pharmacol Ther (1992) 1.23
Inhibition of translation of mRNAs for ornithine decarboxylase and S-adenosylmethionine decarboxylase by polyamines. J Biol Chem (1987) 1.23
Effects of diamines on ornithine decarboxylase activity in control and virally transformed mouse fibroblasts. Biochem J (1979) 1.22
Too Fit To Fracture: outcomes of a Delphi consensus process on physical activity and exercise recommendations for adults with osteoporosis with or without vertebral fractures. Osteoporos Int (2014) 1.22
Increased transfer ribonucleic acid methylase activity in tumours induced in the mouse colon by the administration of 1,2-dimethylhydrazine. Biochem J (1971) 1.22
Mechanisms and regulation of polyamine and putrescine biosynthesis in male genital glands and other tissues of mammals. Adv Enzyme Regul (1969) 1.21
New SMS mutation leads to a striking reduction in spermine synthase protein function and a severe form of Snyder-Robinson X-linked recessive mental retardation syndrome. J Med Genet (2008) 1.20
Effects of inhibitors of spermidine and spermine synthesis on polyamine concentrations and growth of transformed mouse fibroblasts. Biochem J (1981) 1.20
Phase I trial of carmustine plus O6-benzylguanine for patients with recurrent or progressive malignant glioma. J Clin Oncol (2000) 1.19
Effect of chronic treatment of rats with dimethylnitrosamine on the removal of O6-methylguanine from DNA. Cancer Res (1980) 1.19
Regulation of ornithine decarboxylase in a transformed cell line that overexpresses translation initiation factor eIF-4E. Cancer Res (1996) 1.19
Isolation and characterization of a cDNA clone that codes for human spermidine/spermine N1-acetyltransferase. J Biol Chem (1991) 1.18
The effects of diamines and polyamines on enzymic methylation of nucleic acid. Biochim Biophys Acta (1971) 1.18
Health-related quality of life in type 2 diabetes (TARDIS-2). Value Health (2006) 1.18
Properties and physiological function of the polyamine transport system. Am J Physiol (1989) 1.18
Regulation of S-adenosylmethionine decarboxylase activity in rat liver and prostate. J Biol Chem (1985) 1.17
Studies of the induction of spermidine/spermine N1-acetyltransferase using a specific antiserum. J Biol Chem (1984) 1.17
Modulation of potassium channels in the hearts of transgenic and mutant mice with altered polyamine biosynthesis. J Mol Cell Cardiol (2000) 1.16
The crystal structure of human S-adenosylmethionine decarboxylase at 2.25 A resolution reveals a novel fold. Structure (1999) 1.16
Interactions between WHITE Genes Carried by a Large Transposing Element and the ZESTE Allele in DROSOPHILA MELANOGASTER. Genetics (1986) 1.16
Schedule-dependent activity of temozolomide plus CPT-11 against a human central nervous system tumor-derived xenograft. Clin Cancer Res (2000) 1.16
Studies of the specificity and kinetics of rat liver spermidine/spermine N1-acetyltransferase. Biochem J (1983) 1.16
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Purification of rat liver S-adenosyl-L-methionine decarboxylase. Biochem J (1974) 1.15
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Identification of residues in ornithine decarboxylase essential for enzymic activity and for rapid protein turnover. Biochem J (1991) 1.13
Polyamines are needed for the differentiation of 3T3-L1 fibroblasts into adipose cells. Biochem Biophys Res Commun (1981) 1.13
Specific and potent inhibition of spermidine synthase by the transition-state analog, S-adenosyl-3-thio-1,8-diaminooctane. Biochem Biophys Res Commun (1980) 1.13
Resistance of the human O6-alkylguanine-DNA alkyltransferase containing arginine at codon 160 to inactivation by O6-benzylguanine. Cancer Res (1996) 1.12
Translational regulation of ornithine decarboxylase and other enzymes of the polyamine pathway. Int J Biochem Cell Biol (1999) 1.12
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Effect of mutations at active site residues on the activity of ornithine decarboxylase and its inhibition by active site-directed irreversible inhibitors. J Biol Chem (1993) 1.12
Structure and regulation of mammalian S-adenosylmethionine decarboxylase. J Biol Chem (1988) 1.10
Polyamine biosynthesis and interconversion in rodent tissues. Fed Proc (1982) 1.10
DNA binding mechanism of O6-alkylguanine-DNA alkyltransferase: stoichiometry and effects of DNA base composition and secondary structure on complex stability. Biochemistry (1996) 1.09
Purification and characterization of spermidine/spermine N1-acetyltransferase from rat liver. Biochemistry (1982) 1.09
Thresholds of O6-alkylguanine-DNA alkyltransferase which confer significant resistance of human glial tumor xenografts to treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea or temozolomide. Clin Cancer Res (2001) 1.09
Alteration of arginine-128 to alanine abolishes the ability of human O6-alkylguanine-DNA alkyltransferase to repair methylated DNA but has no effect on its reaction with O6-benzylguanine. Biochemistry (1995) 1.09
Alkylation of DNA in rat tissues following administration of streptozotocin. Cancer Res (1981) 1.09
Isolation of human O6-alkylguanine-DNA alkyltransferase mutants highly resistant to inactivation by O6-benzylguanine. Cancer Res (1998) 1.09
Measurement of the number of ornithine decarboxylase molecules in rat and mouse tissues under various physiological conditions by binding of radiolabelled alpha-difluoromethylornithine. Biochem J (1982) 1.09
Direct reversal of DNA damage by mutant methyltransferase protein protects mice against dose-intensified chemotherapy and leads to in vivo selection of hematopoietic stem cells. Cancer Res (2000) 1.08
Role of the carboxyl terminal MATEE sequence of spermidine/spermine N1-acetyltransferase in the activity and stabilization by the polyamine analog N1,N12-bis(ethyl)spermine. Biochemistry (1995) 1.08
Resuscitation of the monkey brain after one hour complete ischemia. III. Indications of metabolic recovery. Brain Res (1975) 1.08
Enzymic synthesis of spermine in rat prostate. Arch Biochem Biophys (1970) 1.08
Ornithine decarboxylase (mouse kidney). Methods Enzymol (1983) 1.08
Escherichia coli S-adenosylhomocysteine/5'-methylthioadenosine nucleosidase. Purification, substrate specificity and mechanism of action. Biochem J (1985) 1.08
The role of polyamine depletion and accumulation of decarboxylated S-adenosylmethionine in the inhibition of growth of SV-3T3 cells treated with alpha-difluoromethylornithine. Biochem J (1984) 1.07
Synthesis and biochemical evaluation of adenosylspermidine, a nucleoside-polyamine adduct inhibitor of spermidine synthase. J Med Chem (1995) 1.07
Comparison of the rates of repair of O6-alkylguanines in DNA by rat liver and bacterial O6-alkylguanine-DNA alkyltransferase. Cancer Res (1984) 1.07
Spermine and spermidine mediate protection against oxidative damage caused by hydrogen peroxide. Amino Acids (2007) 1.07
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Regulation of ornithine decarboxylase activity by spermidine and the spermidine analogue N1N8-bis(ethyl)spermidine. Biochem J (1987) 1.06