Measurement of rates of phagocytosis: the use of cellular monolayers.

PubWeight™: 3.47‹?› | Rank: Top 1%

🔗 View Article (PMC 2107592)

Published in J Cell Biol on January 01, 1969

Authors

R H Michell, S J Pancake, J Noseworthy, M L Karnovsky

Articles citing this

Alterations of macrophage functions by mediators from lymphocytes. J Exp Med (1971) 7.95

The enhancement of bacterial phagocytosis by serum. The role of complement components and two cofactors. J Exp Med (1969) 4.96

Biological defense mechanisms. The effect of bacteria and serum on superoxide production by granulocytes. J Clin Invest (1974) 3.78

Inhibition of phagocytosis and plasma membrane mobility of the cultivated macrophage by cytochalasin B. Role of subplasmalemmal microfilaments. J Cell Biol (1974) 3.46

Superoxide production by phagocytic leukocytes. J Exp Med (1975) 3.43

Localization of NADH oxidase on the surface of human polymorphonuclear leukocytes by a new cytochemical method. J Cell Biol (1975) 3.24

Stimulation of human neutrophils by soluble and insoluble immunoglobulin aggregates. Secretion of granule constituents and increased oxidation of glucose. J Clin Invest (1975) 3.17

Quantitative studies of phagocytosis. Kinetic effects of cations and heat-labile opsonin. J Cell Biol (1973) 3.14

Quantitative studies of phagocytosis by polymorphonuclear leukocytes: use of emulsions to measure the initial rate of phagocytosis. J Clin Invest (1972) 2.88

Endocytosis in Chang liver cells. Quantitation by sucrose- 3 H uptake and inhibition by cytochalasin B. J Cell Biol (1971) 2.63

Effects of anthrax toxin components on human neutrophils. Infect Immun (1985) 2.51

Metabolic and functonal studies on activated mouse macrophages. J Exp Med (1973) 2.17

The distributions of some granule-associated enzymes in guinea-pig polymorphonuclear leucocytes. Biochem J (1970) 2.16

Iodinating ability of various leukocytes and their bactericidal activity. J Exp Med (1973) 1.67

Inhibition of phagocytosis by high molecular weight hyaluronate. Immunology (1980) 1.67

Fate of human lactoferrin and myeloperoxidase in phagocytizing human neutrophils: effects of immunoglobulin G subclasses and immune complexes coated on latex beads. Infect Immun (1975) 1.42

Effect of temperature on phagocytosis by human polymorphonuclear neutrophils. Infect Immun (1975) 1.37

Endocytosis: a review of mechanisms and plasma membrane dynamics. Biochem J (1983) 1.33

The depression of phagocytosis by exogenous cyclic nucleotides, prostaglandins, and theophylline. J Cell Biol (1973) 1.29

Redistribution of membrane-bound and cytosolic action in rabbit polymorphonuclear leucocytes during phagocytosis. Biochem J (1985) 1.11

Alteration of some functional and metabolic characteristics of resident mouse peritoneal macrophages by lymphocyte mediators. J Exp Med (1978) 1.03

Replication of herpes simplex virus type 1 in macrophages from resistant and susceptible mice. Infect Immun (1979) 1.02

Effects of anti-human neutrophil antibodies in vitro. Quantitative studies. J Clin Invest (1974) 1.02

Quantitative measurement of phagocytosis of Neisseria gonorrhoeae by mouse peritoneal macrophages. Infect Immun (1978) 0.90

Contribution of immunoglobulins M and G, complement, and properdin to the intracellular killing of Escherichia coli by polymorphonuclear leukocytes. Infect Immun (1978) 0.88

Impaired nonspecific cellular immunity in experimental cholestasis. Ann Surg (1987) 0.87

Quatification of phagocytosis by human neutrophils. The use of radiolabelled staphylococcal protein A-IgG complexes. Immunology (1976) 0.87

Phagocytosis by the cellular slime mold Polysphondylium pallidum during growth and development. J Cell Biol (1973) 0.86

Application of differential scanning microcalorimetry to the study of cellular processes: heat production and glucose oxidation of murine macrophages. Proc Natl Acad Sci U S A (1981) 0.86

Gonococci-human polymorphonuclear leukocyte interactions: metabolic studies associated with attachment and ingestion. Infect Immun (1980) 0.85

Nanoparticle Uptake: The Phagocyte Problem. Nano Today (2015) 0.84

Phagocytosis. Clinical disorders of recognition and ingestion. Am J Pathol (1977) 0.84

Macrophage deformability and phagocytosis. J Cell Biol (1977) 0.82

Oxidative decarboxylation of free and peptide-linked amino acids in phagocytizing guinea pig granulocytes. J Clin Invest (1981) 0.81

Murine cellular cytotoxicity to syngeneic and xenogeneic herpes simplex virus-infected cells. Infect Immun (1982) 0.81

Attachment and ingestion of mycoplasmas by mouse macrophages. I. Kinetics of the interaction and effects on phagocyte glucose metabolism. Am J Pathol (1977) 0.80

The determination and localization of sialic acid in guinea-pig granulocytes. Biochem J (1980) 0.80

Metabolic and functional characteristics of alveolar macrophages recovered from rats exposed to marijuana smoke. Infect Immun (1979) 0.76

The effects of clofibrate ingestion on alveolar macrophage peroxisome content and oxygen metabolism. Agents Actions (1982) 0.75

Functional and metabolic properties of alveolar macrophages in response to the gas phase of tobacco smoke. Infect Immun (1981) 0.75

Effect of surface modifiers on an ectoenzyme: granulocyte 5'-nucleotidase. Infect Immun (1980) 0.75

Articles cited by this

Protein measurement with the Folin phenol reagent. J Biol Chem (1951) 1743.91

The biochemical basis of phagocytosis. I. Metabolic changes during the ingestion of particles by polymorphonuclear leukocytes. J Biol Chem (1959) 17.39

Interactions between rabbit polymorphonuclear leucocytes and staphylococci. J Exp Med (1959) 17.17

Metabolic patterns in three types of phagocytizing cells. J Cell Biol (1963) 8.92

A simple scintillation counting technique for assaying C1402 in a Warburg flask. Anal Biochem (1962) 4.70

The dissociation by colchicine of phagocytosis from increased oxygen consumption in human leukocytes. J Clin Invest (1967) 4.22

Metabolic and morphological observations on the effect of surface-active agents of leukocytes. J Cell Biol (1967) 3.53

Phagocytosis of latex beads by Acanthamoeba. I. Biochemical properties. Biochemistry (1967) 3.45

Methods for the study of surviving leukocytes: A. Preparation of cell suspension. Methods Med Res (1958) 3.08

PARTICLE UPTAKE BY POLYMORPHONUCLEAR LEUCOCYTES AND EHRLICH ASCITES-CARCINOMA CELLS. Biochem J (1963) 2.52

The physiological role of the lymphoid system. VI. The stimulatory effect of leucophilic gamma globulin (leucokinin) on the phagocytic activity of human polymorphonuclear leucocyte. Biochemistry (1967) 1.86

Studies on the role of phospholipids in phagocytosis. J Biol Chem (1966) 1.62

Preparation of an artificial antigen and immunity to mouse typhoid. Immunology (1967) 1.33

Phagocytosis by guinea pig splenic cells of Escherichia coli and protein-coated bentonite particles labeled with iodine-125. J Immunol (1966) 1.22

Uptake by mononuclear phagocytes of protein-coated bentonite particles stabilized with a carbodiimide. J Immunol (1967) 1.19

Use of radioactive isotopes in studies on phagocytosis in vitro. Nature (1966) 0.94

Articles by these authors

Inositol phospholipids and cell surface receptor function. Biochim Biophys Acta (1975) 11.82

Alterations of macrophage functions by mediators from lymphocytes. J Exp Med (1971) 7.95

The inositol trisphosphate phosphomonoesterase of the human erythrocyte membrane. Biochem J (1982) 6.82

The polyphosphoinositide phosphodiesterase of erythrocyte membranes. Biochem J (1981) 6.16

Active oxygen species and the functions of phagocytic leukocytes. Annu Rev Biochem (1980) 5.86

The natural history of multiple sclerosis: a geographically based study. I. Clinical course and disability. Brain (1989) 5.59

The stimulation of inositol lipid metabolism that accompanies calcium mobilization in stimulated cells: defined characteristics and unanswered questions. Philos Trans R Soc Lond B Biol Sci (1981) 5.30

Rapid breakdown of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate in rat hepatocytes stimulated by vasopressin and other Ca2+-mobilizing hormones. Biochem J (1983) 4.11

Biochemical criteria for activated macrophages. J Immunol (1978) 3.74

The metabolism of leukocytes. Semin Hematol (1968) 3.55

Metabolic and morphological observations on the effect of surface-active agents of leukocytes. J Cell Biol (1967) 3.53

Osmotic stress activates phosphatidylinositol-3,5-bisphosphate synthesis. Nature (1997) 3.50

The site of diphosphoinositide synthesis in rat liver. Biochem Biophys Res Commun (1965) 3.49

Stepwise enzymatic dephosphorylation of inositol 1,4,5-trisphosphate to inositol in liver. Nature (1984) 3.46

Superoxide production by phagocytic leukocytes. J Exp Med (1975) 3.43

Localization of NADH oxidase on the surface of human polymorphonuclear leukocytes by a new cytochemical method. J Cell Biol (1975) 3.24

Degranulation of leukocytes in chronic granulomatous disease. J Clin Invest (1969) 3.17

Plasma membranes of mammalian cells: a review of methods for their characterization and isolation. J Cell Biol (1973) 2.99

Respiration and glucose oxidation in human and guinea pig leukocytes: comparative studies. J Clin Invest (1970) 2.83

Hormone-stimulated metabolism of inositol lipids and its relationship to hepatic receptor function. Biochem Soc Trans (1981) 2.73

Ecto-enzymes of the guinea pig polymorphonuclear leukocyte. I. Evidence for an ecto-adenosine monophosphatase, adenosine triphosphatase, and -p-nitrophenyl phosphates. J Biol Chem (1974) 2.65

The natural history of multiple sclerosis: a geographically based study. 2. Predictive value of the early clinical course. Brain (1989) 2.59

Deficiency of reduced nicotinamide-adenine dinucleotide oxidase in chronic granulomatous disease. Science (1968) 2.56

A calcium-activated polyphosphoinositide phosphodiesterase in the plasma membrane of human and rabbit erythrocytes. Biochim Biophys Acta (1978) 2.45

Phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate: lipids in search of a function. Cell Calcium (1982) 2.39

The physicochemical characteristics and purification of slow-reacting substance of anaphylaxis. J Immunol (1973) 2.34

Metabolic and functonal studies on activated mouse macrophages. J Exp Med (1973) 2.17

The distributions of some granule-associated enzymes in guinea-pig polymorphonuclear leucocytes. Biochem J (1970) 2.16

Similar effects of substance P and related peptides on salivation and on phosphatidylinositol turnover in rat salivary glands. Mol Pharmacol (1980) 2.14

Hormonal stimulation of phosphatidylinositol breakdown with particular reference to the hepatic effects of vasopressin. Biochem Soc Trans (1979) 2.12

Chronic granulomatous disease--pieces of a cellular and molecular puzzle. Fed Proc (1973) 2.08

Correction of metabolic deficiencies in the leukocytes of patients with chronic granulomatous disease. J Clin Invest (1970) 2.04

Extraction of sleep-promoting factor S from cerebrospinal fluid and from brains of sleep-deprived animals. J Neurophysiol (1975) 2.04

Dephosphorylation of myo-inositol 1,4,5-trisphosphate and myo-inositol 1,3,4-triphosphate. Biochem J (1987) 1.98

The stress-activated phosphatidylinositol 3-phosphate 5-kinase Fab1p is essential for vacuole function in S. cerevisiae. Curr Biol (1998) 1.95

Breakdown of phosphatidylinositol provoked by muscarinic cholinergic stimulation of rat parotid-gland fragments. Biochem J (1974) 1.93

A purified plasma membrane fraction isolated from rat liver under isotonic conditions. Biochim Biophys Acta (1967) 1.86

Metabolism of D-myo-inositol 1,3,4,5-tetrakisphosphate by rat liver, including the synthesis of a novel isomer of myo-inositol tetrakisphosphate. Biochem J (1987) 1.86

Synthesis and release of thymidine by macrophages. J Immunol (1977) 1.77

Accumulation of 1,2-diacylglycerol in the plasma membrane may lead to echinocyte transformation of erythrocytes. Nature (1975) 1.77

cis-Polyunsaturated fatty acids induce high levels of superoxide production by human neutrophils. J Biol Chem (1981) 1.75

Release of diacylglycerol-enriched vesicles from erythrocytes with increased intracellular (Ca2+). Nature (1976) 1.74

Phosphatidylinositol metabolism in rat hepatocytes stimulated by vasopressin. Biochem J (1981) 1.72

Phosphatidylinositol cleavage in lymphocytes. Requirement for calcium ions at a low concentration and effects of other cations. Biochem J (1974) 1.70

Diacylglycerols and phosphatidates: which molecular species are intracellular messengers? Trends Biochem Sci (1998) 1.69

Identification of ARAP3, a novel PI3K effector regulating both Arf and Rho GTPases, by selective capture on phosphoinositide affinity matrices. Mol Cell (2002) 1.69

Multiple metabolic pools of phosphoinositides and phosphatidate in human erythrocytes incubated in a medium that permits rapid transmembrane exchange of phosphate. Biochem J (1987) 1.68

Iodinating ability of various leukocytes and their bactericidal activity. J Exp Med (1973) 1.67

Incorporation of phosphate into diphosphoinositide by subcellular fractions from liver. Biochim Biophys Acta (1965) 1.66

Rapid transbilayer diffusion of 1,2-diacylglycerol and its relevance to control of membrane curvature. Nature (1978) 1.64

Production of 1,2-diacylglycerol and phosphatidate in human erythrocytes treated with calcium ions and ionophore A23187. Biochem J (1976) 1.63

Analysis of the metabolic turnover of the individual phosphate groups of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate. Validation of novel analytical techniques by using 32P-labelled lipids from erythrocytes. Biochem J (1984) 1.61

Effects of free fatty acids on release of superoxide and on change of shape by human neutrophils. Reversibility by albumin. J Biol Chem (1984) 1.57

Changes in lipid metabolism and cell morphology following attack by phospholipase C (Clostridium perfringens) on red cells or lymphocytes. Biochim Biophys Acta (1975) 1.56

Biochemical characteristics of activated macrophages. Ann N Y Acad Sci (1975) 1.56

Phosphatidylinositol metabolism in rat hepatocytes stimulated by glycogenolytic hormones. Effects of angiotensin, vasopressin, adrenaline, ionophore A23187 and calcium-ion deprivation. Biochem J (1979) 1.55

The relationship of calcium to receptor-controlled stimulation of phosphatidylinositol turnover. Effects of acetylcholine, adrenaline, calcium ions, cinchocaine and a bivalent cation ionophore on rat parotid-gland fragments. Biochem J (1975) 1.53

A membrane-bound activity catalysing phosphatidylinositol breakdown to 1,2-diacylglycerol, D-myoinositol 1:2-cyclic phosphate an D-myoinositol 1-phosphate. Properties and subcellular distribution in rat cerebral cortex. Biochem J (1973) 1.53

Phosphatidylinositol cleavage catalysed by the soluble fraction from lymphocytes. Activity at pH5.5 and pH7.0. Biochem J (1974) 1.52

Stages in the incorporation of fatty acids into red blood cells. J Clin Invest (1968) 1.49

Rapid accumulation of inositol phosphates in isolated rat superior cervical sympathetic ganglia exposed to V1-vasopressin and muscarinic cholinergic stimuli. Biochem J (1984) 1.49

Receptor occupancy dose--response curve suggests that phosphatidyl-inositol breakdown may be intrinsic to the mechanism of the muscarinic cholinergic receptor. FEBS Lett (1976) 1.49

The possible involvement of phosphatidylinositol breakdown in the mechanism of stimulus-response coupling at receptors which control cell-surface calcium gates. Adv Exp Med Biol (1977) 1.49

Ecto-enzyme of granulocytes: 5'-nucleotidase. Science (1974) 1.46

The composition of sleep-promoting factor isolated from human urine. J Biol Chem (1982) 1.46

Sleep-promoting effects of muramyl peptides. Proc Natl Acad Sci U S A (1982) 1.46

Stimulation by acetylcholine of phosphatidylinositol labelling. Subcellular distribution in rat cerebral-cortex slices. Biochem J (1972) 1.45

Biochemical basis of phagocytosis. V. Effect of phagocytosis on cellular uptake of extracellular fluid, and on the intracellular pool of L-alpha-glycerophosphate. Fed Proc (1966) 1.45

The control by Ca2+ of the polyphosphoinositide phosphodiesterase and the Ca2+-pump ATPase in human erythrocytes. Biochem J (1982) 1.44

Phagocytosis and the sialic acid of the surface of polymorphonuclear leukocytes. J Cell Physiol (1972) 1.42

Effects of calcium-antagonistic drugs on the stimulation by carbamoylcholine and histamine of phosphatidylinositol turnover in longitudinal smooth muscle of guinea-pig ileum. Biochem J (1976) 1.40

Peptidoglycans as promoters of slow-wave sleep. II. Somnogenic and pyrogenic activities of some naturally occurring muramyl peptides; correlations with mass spectrometric structure determination. J Biol Chem (1984) 1.39

Complementation analysis in PtdInsP kinase-deficient yeast mutants demonstrates that Schizosaccharomyces pombe and murine Fab1p homologues are phosphatidylinositol 3-phosphate 5-kinases. J Biol Chem (1999) 1.39

Ecto-enzymes of the guinea pig polymorphonuclear leukocyte. II. Properties and suitability as markers for the plasma membrane. J Biol Chem (1974) 1.38

Calcium ion-dependent diacylglycerol accumulation in erythrocytes is associated with microvesiculation but not with efflux of potassium ions. Biochem J (1977) 1.35

Preparation of an artificial antigen and immunity to mouse typhoid. Immunology (1967) 1.33

The labelling of polyphosphoinositides with [32P]Pi and the accumulation of inositol phosphates in vasopressin-stimulated hepatocytes. Biochem J (1986) 1.31

Stimulation of phosphatidylinositol turnover in various tissues by cholinergic and adrenergic agonists, by histamine and by caerulein. Biochem J (1979) 1.31

Enhanced synthesis de novo of phosphatidylinositol in lymphocytes treated with cationic amphiphilic drugs. Biochem J (1975) 1.30

Inhibition of phosphatases and increased Ca2+ channel activity by inositol hexakisphosphate. Science (1997) 1.30

The depression of phagocytosis by exogenous cyclic nucleotides, prostaglandins, and theophylline. J Cell Biol (1973) 1.29

Stimulated inositol lipid metabolism: an introduction. Cell Calcium (1982) 1.28

Pasteurella multocida toxin, a potent mitogen, increases inositol 1,4,5-trisphosphate and mobilizes Ca2+ in Swiss 3T3 cells. J Biol Chem (1991) 1.26

Turkey erythrocytes possess a membrane-associated inositol 1,4,5-trisphosphate 3-kinase that is activated by Ca2+ in the presence of calmodulin. Biochem J (1987) 1.26

Detergent solubilization and partial purification of tumor specific surface and transplantation antigens from SV40-virus-transformed mouse cells. Int J Cancer (1977) 1.25

Characteristics of rat liver phosphatidylinositol kinase and its presence in the plasma membrane. Biochim Biophys Acta (1967) 1.25

Selective release of plasma-membrane enzymes from rat hepatocytes by a phosphatidylinositol-specific phospholipase C. Biochem J (1980) 1.23

A combination of calcium ionophore and 12-O-tetradecanoyl-phorbol-13-acetate (TPA) stimulates the growth of purified resting B cells. Scand J Immunol (1985) 1.23

The opening of the inositol 1,4,5-trisphosphate-sensitive Ca2+ channel in rat cerebellum is inhibited by caffeine. Biochem J (1992) 1.23

Production of 1,2-diacylglycerol in human erythrocyte membranes exposed to low concentrations of calcium ions. Biochim Biophys Acta (1976) 1.23

Fluoride-mediated activation of the respiratory burst in human neutrophils. A reversible process. J Clin Invest (1979) 1.23

Enhanced phosphatidylinositol labelling in rat parotid fragments exposed to alpha-adrenergic stimulation. Biochem J (1974) 1.22

Studies on the mechanism of superoxide release from human neutrophils stimulated with arachidonate. J Biol Chem (1984) 1.22

Inositol lipid metabolism in dividing and differentiating cells. Cell Calcium (1982) 1.21

Factors that control the effect of pH on glycolysis in leukocytes. J Biol Chem (1969) 1.20

Are polyphosphoinositides associated with glycophorin in human erythrocyte membranes? Biochem J (1979) 1.20

Comparison of the levels of inositol metabolites in transformed haemopoietic cells and their normal counterparts. Biochem J (1993) 1.19

Phosphatidylinositol metabolism in cells receiving extracellular stimulation. FEBS Lett (1973) 1.19