Published in J Biol Chem on October 10, 1984
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Regulation of phagocyte oxygen radical production by the GTP-binding protein Rac 2. Science (1991) 3.87
Biological defense mechanisms. The effect of bacteria and serum on superoxide production by granulocytes. J Clin Invest (1974) 3.78
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Endothelial regeneration in the rat carotid artery and the significance of endothelial denudation in the pathogenesis of myointimal thickening. Lab Invest (1975) 2.88
A comparative evaluation of the distribution of concanavalin A-binding sites on the surfaces of normal, virally-transformed, and protease-treated fibroblasts. Proc Natl Acad Sci U S A (1973) 2.88
Respiration and glucose oxidation in human and guinea pig leukocytes: comparative studies. J Clin Invest (1970) 2.83
An ultrastructural study of lymphocytes with surface-bound immunoglobulin. J Exp Med (1972) 2.65
Biological defense mechanisms. Evidence for the participation of superoxide in bacterial killing by xanthine oxidase. J Lab Clin Med (1975) 2.65
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Deficiency of reduced nicotinamide-adenine dinucleotide oxidase in chronic granulomatous disease. Science (1968) 2.56
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The particulate superoxide-forming system from human neutrophils. Properties of the system and further evidence supporting its participation in the respiratory burst. J Clin Invest (1976) 2.43
Inhibition of rat arterial smooth muscle cell proliferation by heparin. II. In vitro studies. Circ Res (1980) 2.40
Neutrophil nicotinamide adenine dinucleotide phosphate oxidase assembly. Translocation of p47-phox and p67-phox requires interaction between p47-phox and cytochrome b558. J Clin Invest (1991) 2.38
The physicochemical characteristics and purification of slow-reacting substance of anaphylaxis. J Immunol (1973) 2.34
Subcellular localization of the superoxide-forming enzyme in human neutrophils. J Clin Invest (1979) 2.33
Contraction of cultured rat glomerular cells of apparent mesangial origin after stimulation with angiotensin II and arginine vasopressin. J Clin Invest (1980) 2.32
An inherited abnormality of neutrophil adhesion. Its genetic transmission and its association with a missing protein. N Engl J Med (1980) 2.32
The concept of lipid domains in membranes. J Cell Biol (1982) 2.26
Evidence for a blood-thymus barrier using electron-opaque tracers. J Exp Med (1972) 2.18
Metabolic and functonal studies on activated mouse macrophages. J Exp Med (1973) 2.17
The distributions of some granule-associated enzymes in guinea-pig polymorphonuclear leucocytes. Biochem J (1970) 2.16
Ischemic stroke injury is reduced in mice lacking a functional NADPH oxidase. Stroke (1997) 2.14
The adhesive interaction between polymorphonuclear leukocytes and endothelial cells in vitro. Cell (1978) 2.13
An ultrastructural staining method for enhancing the size and electron opacity of ferritin in thin sections. J Histochem Cytochem (1972) 2.12
Infection with Pseudomonas cepacia in chronic granulomatous disease: role of nonoxidative killing by neutrophils in host defense. J Infect Dis (1994) 2.12
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Ligand-induced movement of lymphocyte membrane macromolecules. 3. Relationship between the formation and fate of anti-Ig-surface Ig complexes and cell metabolism. J Exp Med (1973) 2.08
Leukotriene B4 action on endothelium mediates augmented neutrophil/endothelial adhesion. Proc Natl Acad Sci U S A (1984) 2.06
Activation of human neutrophil nicotinamide adenine dinucleotide phosphate, reduced (triphosphopyridine nucleotide, reduced) oxidase by arachidonic acid in a cell-free system. J Clin Invest (1985) 2.06
Medical screening of old people accepted for residential care. Lancet (1978) 2.06
Defect in pyridine nucleotide dependent superoxide production by a particulate fraction from the cranulocytes of patients with chronic granulomatous disease. N Engl J Med (1975) 2.05
Correction of metabolic deficiencies in the leukocytes of patients with chronic granulomatous disease. J Clin Invest (1970) 2.04
Extraction of sleep-promoting factor S from cerebrospinal fluid and from brains of sleep-deprived animals. J Neurophysiol (1975) 2.04
Degradation of abnormal proteins in Escherichia coli. Formation of protein inclusions in cells exposed to amino acid analogs. J Biol Chem (1975) 2.03
An ultrastructural study of the mechanisms of proteinuria in aminonucleoside nephrosis. Kidney Int (1975) 2.01
Inhibition of rat arterial smooth muscle cell proliferation by heparin. In vivo studies with anticoagulant and nonanticoagulant heparin. Circ Res (1980) 2.00
The ultrastructural basis of alveolar-capillary membrane permeability to peroxidase used as a tracer. J Cell Biol (1968) 1.99
Inhibition of vascular smooth muscle cell growth by endothelial cell-derived heparin. Possible role of a platelet endoglycosidase. J Biol Chem (1982) 1.99
Genetic variants of chronic granulomatous disease: prevalence of deficiencies of two cytosolic components of the NADPH oxidase system. N Engl J Med (1989) 1.93
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Human neutrophil cytochrome b light chain (p22-phox). Gene structure, chromosomal location, and mutations in cytochrome-negative autosomal recessive chronic granulomatous disease. J Clin Invest (1990) 1.91
Adhesion of leukocytes to endothelium: roles of divalent cations, surface charge, chemotactic agents and substrate. J Cell Sci (1980) 1.90
Irreversible deformation of the spectrin-actin lattice in irreversibly sickled cells. J Clin Invest (1976) 1.89
Redistribution and fate of Ig complexes on surface of B lymphocytes: functional implications and mechanisms. Transplant Rev (1973) 1.88
Distribution of endogenous albumin in the rat glomerulus: role of hemodynamic factors in glomerular barrier function. Kidney Int (1976) 1.88
The structure of the zonula occludens. A single fibril model based on freeze-fracture. J Cell Biol (1974) 1.87
Effects of anaerobiosis and inhibitors on O2-production by human granulocytes. Blood (1975) 1.85
Isolation and characterization of rat glomerular epithelial cells in vitro. Kidney Int (1978) 1.83
Factors affecting the redistribution of surface-bound concanavalin A on human polymorphonuclear leukocytes. J Cell Biol (1974) 1.78
Synthesis and release of thymidine by macrophages. J Immunol (1977) 1.77
Inhibition of surface capping of macromolecules by local anaesthetics and tranquillisers. Nature (1974) 1.75
cis-Polyunsaturated fatty acids induce high levels of superoxide production by human neutrophils. J Biol Chem (1981) 1.75
Autophagic vacuoles in experimental atrophy. Exp Mol Pathol (1971) 1.75
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Rac translocates independently of the neutrophil NADPH oxidase components p47phox and p67phox. Evidence for its interaction with flavocytochrome b558. J Biol Chem (1994) 1.74
Endocytosis by lymphocytes of complexes of anti-Ig with membrane-bound Ig. J Immunol (1972) 1.73
Valaciclovir for the suppression of recurrent genital herpes simplex virus infection: a large-scale dose range-finding study. International Valaciclovir HSV Study Group. J Infect Dis (1998) 1.72
An ultrastructural study of glomerular permeability using catalase and peroxidase as tracer proteins. J Exp Med (1970) 1.70
Purification and characterization of Rac 2. A cytosolic GTP-binding protein that regulates human neutrophil NADPH oxidase. J Biol Chem (1992) 1.69
Activation of neutrophil NADPH oxidase in a cell-free system. Partial purification of components and characterization of the activation process. J Biol Chem (1987) 1.68
Vascular leakage induced by horseradish peroxidase in the rat. Proc Soc Exp Biol Med (1967) 1.67
Iodinating ability of various leukocytes and their bactericidal activity. J Exp Med (1973) 1.67
Exogenous cytochrome c as an ultrastructural tracer. J Histochem Cytochem (1969) 1.65
Early and persistent induction of monocyte chemoattractant protein 1 in rat cardiac allografts. Proc Natl Acad Sci U S A (1993) 1.61