PubRank

J J Schildkraut

Author PubWeight™ 68.21‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The catecholamine hypothesis of affective disorders: a review of supporting evidence. Am J Psychiatry 1965 5.09
2 Biogenic amines and emotion. Science 1967 3.49
3 Metabolism of normetanephrine-H3 in rat brain--identification of conjugated 3-methoxy-4-hydrophenylglycol as the major metabolite. Biochem Pharmacol 1968 1.86
4 The effects of psychoactive drugs on norepinephrine-3-H metabolism in brain. Biochem Pharmacol 1967 1.54
5 Clozapine for comorbid substance use disorder and schizophrenia: do patients with schizophrenia have a reward-deficiency syndrome that can be ameliorated by clozapine? Harv Rev Psychiatry 1999 1.21
6 The catecholamine hypothesis of affective disorders: a review of supporting evidence. 1965. J Neuropsychiatry Clin Neurosci 1995 1.14
7 The current status of biological criteria for classifying the depressive disorders and predicting responses to treatment. Psychopharmacol Bull 1974 1.06
8 Norepinephrine metabolites as biochemical criteria for classifying depressive disorders and predicting responses to treatment: preliminary findings. Am J Psychiatry 1973 0.99
9 Diurnal variation of plasma cortisol and homovanillic acid in healthy subjects. Psychoneuroendocrinology 1996 0.97
10 Normetanephrine excretion and affective state in depressed patients treated with imipramine. Am J Psychiatry 1966 0.97
11 Amphetamine withdrawal: affective state, sleep patterns, and MHPG excretion. Am J Psychiatry 1972 0.96
12 The effects of delta-9-tetrahydrocannabinol on the metabolism of norepinephrine in rat brain. Psychopharmacologia 1971 0.93
13 Amphetamine withdrawal: effects on threshold of intracranial reinforcement. Psychopharmacology (Berl) 1981 0.92
14 Tranylcypromine: effects on norepinephrine metabolism in rat brain. Am J Psychiatry 1970 0.91
15 Norepinephrine metabolism and drugs used in the affective disorders: a possible mechanism of action. Am J Psychiatry 1967 0.91
16 Hypomanic reactions to ACTH and prednisone treatment for multiple sclerosis. Neurology 1988 0.89
17 Neuropharmacology of the affective disorders. Annu Rev Pharmacol 1973 0.89
18 Amitriptyline in the treatment of anorexia nervosa: a double-blind, placebo-controlled study. J Clin Psychopharmacol 1985 0.89
19 Desynchronized sleep and MHPG excretion: an inverse correlation. Brain Res 1973 0.88
20 Biogenic amines and affective disorders. Annu Rev Med 1974 0.87
21 Alterations in brain norepinephrine metabolism induced by environmental stimuli previously paired with inescapable shock. Science 1980 0.86
22 Toward a biochemical classification of depressive disorders--VIII. Platelet monoamine oxidase activity in subtypes of depressions. J Psychiatr Res 1985 0.85
23 Effects of 6-hydroxydopamine on sleep in the rat. Nature 1971 0.85
24 Should clozapine be a first-line treatment for schizophrenia? The rationale for a double-blind clinical trial in first-episode patients. Harv Rev Psychiatry 1997 0.85
25 Toward a biochemical classification of depressive disorders. I. Differences in urinary excretion of MHPG and other catecholamine metabolites in clinically defined subtypes of depressions. Arch Gen Psychiatry 1978 0.84
26 The effects of tranylcypromine isomers on norepinephrine-H3 metabolism in rat brain. Psychopharmacology (Berl) 1980 0.83
27 Alpha-methylparatyrosine and sleep in the rat. Psychopharmacologia 1971 0.83
28 Catecholamine metabolism in affective disorders. IV. Preliminary studies of norepinephrine metabolism in depressed patients treated with amitriptyline. J Psychiatr Res 1972 0.82
29 Catecholamine metabolism in affective disorders. I. Normetanephrine and VMA excretion in depressed patients treated with imipramine. J Psychiatr Res 1965 0.82
30 Amphetamine withdrawal: depression and M.H.P.G. excretion. Lancet 1971 0.82
31 Alterations in brain norepinephrine metabolism and behavior induced by environmental stimuli previously paired with inescapable shock. Behav Brain Res 1981 0.81
32 Abnormal flash visual evoked response in melancholia: a replication study. Biol Psychiatry 1992 0.81
33 Effects of tricyclic antidepressants on the uptake and mabolism of intracisternally administered norepinephrine-H3 in rat brain. J Psychiatr Res 1969 0.81
34 Norepinephrine metabolism in the rat brain following acute and chronic administration of thyrotropin releasing hormone. Psychopharmacologia 1974 0.81
35 Clinical utility of tricyclic antidepressant blood levels: a case report. Am J Psychiatry 1979 0.81
36 Hypothalamic-pituitary-adrenal axis activity and 1-year outcome in depression. Biol Psychiatry 1993 0.81
37 Late feedback effects of hypothalamic-pituitary-adrenal axis hormones in healthy subjects. Psychoneuroendocrinology 1998 0.81
38 Norepinephrine turnover and metabolism in rat brain after long-term administration of imipramine. Science 1970 0.81
39 The effects of pentobarbital on the fate of intracisternally administered norepinephrine-H3. J Pharmacol Exp Ther 1967 0.80
40 Changes in norepinephrine output following light therapy for fall/winter seasonal depression. Biol Psychiatry 1992 0.80
41 The catecholamine hypothesis of affective disorders. A review of supporting evidence. Int J Psychiatry 1967 0.80
42 Biochemical criteria for classifying depressive disorders and predicting responses to pharmacotherapy: preliminary findings from studies of norepinephrine metabolism. Contributions to biochemistry. Pharmakopsychiatr Neuropsychopharmakol 1974 0.80
43 Reduced platelet monoamine oxidase activity in a subgroup of schizophrenic patients. Am J Psychiatry 1976 0.79
44 Signal transduction by platelet adenylate cyclase: alterations in depressed patients may reflect impairment in the coordinated integration of cellular signals (coincidence detection). Biol Psychiatry 1998 0.79
45 The effects of lithium ion on H3-norepinephrine metabolism in brain. Life Sci 1966 0.79
46 Effects of psychoactive drugs on the metabolism of intracisternally administered serotonin in rat brain. Biochem Pharmacol 1969 0.79
47 Catecholamine metabolism in affective disorders. 3. MHPG and other catecholamine metabolites in patients treated with lithium carbonate. J Psychiatr Res 1970 0.78
48 Changes in norepinephrine turnover in rat brain during chronic administration of imipramine and protriptyline: a possible explanation for the delay in onset of clinical antidepressant effects. Am J Psychiatry 1971 0.78
49 Rapid antidepressant response to alprazolam in depressed patients with high catecholamine output and heterologous desensitization of platelet adenylate cyclase. Biol Psychiatry 1988 0.78
50 M.H.P.G. excretion and clinical classification in depressive disorders. Lancet 1973 0.77
51 Cortisol feedback effects on plasma corticotropin levels in healthy subjects. Psychoneuroendocrinology 1997 0.77
52 Platelet MAO activity and the dexamethasone suppression test in depressed patients. Am J Psychiatry 1983 0.77
53 Clozapine response and plasma catecholamines and their metabolites. Psychiatry Res 1993 0.77
54 Toward a biochemical classification of depressive disorders, V: Heterogeneity of unipolar depressions. Am J Psychiatry 1982 0.77
55 Toward a biochemical classification of depressive disorders. X. Urinary catecholamines, their metabolites, and D-type scores in subgroups of depressive disorders. Arch Gen Psychiatry 1989 0.77
56 Norepinephrine content of various rat organs after chronic administration of desmethylimipramine. Arch Int Pharmacodyn Ther 1975 0.77
57 Amphetamine withdrawal: effects on brain levels of MHPG-SO4 in the rat. Commun Psychopharmacol 1979 0.77
58 Determination of urinary normetanephrine and metanephrine by radial-compression liquid chromatography and electrochemical detection. Clin Chem 1983 0.77
59 Toward a biochemical classification of depressive disorders IV: Pretreatment urinary MHPG levels as predictors of antidepressant response to imipramine. Commun Psychopharmacol 1980 0.76
60 Toward a biochemical classification of depressive disorders. III: Pretreatment urinary MHPG levels as predictors of response to treatment with maprotiline. Psychopharmacology (Berl) 1981 0.76
61 Urinary MHPG and clinical symptoms in patients with unipolar depression. Psychiatry Res 1994 0.76
62 Differences in platelet monoamine oxidase activity in subgroups of schizophrenic and depressive disorders. Biol Psychiatry 1978 0.76
63 Focal cerebral perfusion defects demonstrated by 99mTc-hexamethylpropyleneamine oxime SPECT in elderly depressed patients. Psychiatry Res 1996 0.76
64 Pretreatment urinary MHPG levels as predictors of antidepressant responses to alprazolam. Am J Psychiatry 1985 0.76
65 Catecholamines in affective disorders. Psychopharmacol Bull 1975 0.76
66 Catecholamine metabolism during heroin use. Am J Psychiatry 1977 0.76
67 Hypothalamic-pituitary-adrenal axis effects on plasma homovanillic acid in man. Biol Psychiatry 1999 0.76
68 Sodium inhibits both adenylate cyclase and high-affinity 3H-labeled p-aminoclonidine binding to alpha 2-adrenergic receptors in purified human platelet membranes. Mol Pharmacol 1982 0.76
69 Abnormal visual evoked response in melancholia. Biol Psychiatry 1989 0.75
70 The effects of heroin on catecholamine metabolism in man. Natl Inst Drug Abuse Res Monogr Ser 1975 0.75
71 Psychotic and nonpsychotic depressions: II. Platelet MAO activity, plasma catecholamines, cortisol, and specific symptoms. Psychiatry Res 1987 0.75
72 Neuropsychopharmacology and the affective disorders (second of three parts). N Engl J Med 1969 0.75
73 Platelet monoamine oxidase activity in subgroups of schizophrenic disorders. Schizophr Bull 1980 0.75
74 Opiates, catecholamines, behavior, and mood. Psychopharmacology (Berl) 1978 0.75
75 The effects of acute and chronic administration of morphine on norepinephrine turnover in rat brain regions. Biochem Pharmacol 1977 0.75
76 The biochemical discrimination of subtypes of depressive disorders: an outline of our studies on norepinephrine metabolism and psychoactive drugs in the endogenous depressions since 1967. Pharmacopsychiatria 1982 0.75
77 Heterogeneity in anorexia nervosa. Biol Psychiatry 1986 0.75
78 Neuropsychopharmacology and the affective disorders. (First of three parts). N Engl J Med 1969 0.75
79 Psychopharmacology of biogenic amines in depressions. Psychopharmacol Bull 1975 0.75
80 Toward a biochemical classification of depressive disorders, VI: Platelet MAO activity and clinical symptoms in depressed patients. Am J Psychiatry 1982 0.75
81 Enhanced signal transduction by adenylate cyclase in platelet membranes of patients showing antidepressant responses to alprazolam: preliminary data. J Psychiatr Res 1985 0.75
82 MHPG as a predictor of antidepressant response to imipramine and maprotiline. Am J Psychiatry 1980 0.75
83 Toward a biochemical classification of depressive disorders IX. DST results and platelet MAO activity. Br J Psychiatry 1985 0.75
84 Learned helplessness and urinary MHPG levels in unipolar depression. Am J Psychiatry 1992 0.75
85 Preliminary findings on the effects of amitriptyline on norepinephrine-H3 metabolism in rat brain. Dis Nerv Syst 1969 0.75
86 The effects of acute and chronic administration of tricyclic antidepressants on MHPG-SO4 in rat brain. Commun Psychopharmacol 1977 0.75
87 A biopsychosocial approach to treating patients with affective disorders. Am J Psychiatry 1987 0.75
88 MHPG excretion in depressive disorders: relation to clinical subtypes and desynchronized sleep. Science 1973 0.75
89 Proceedings: Norepinephrine metabolism in subtypes of depressive disorders. Psychopharmacol Bull 1974 0.75
90 Neuropsychopharmacology and the affective disorders. (Third of three parts) N Engl J Med 1969 0.75
91 Haloperidol response and plasma catecholamines and their metabolites. Schizophr Res 1993 0.75
92 Toward a biochemical classification of depressive disorders. II. Application of multivariate discriminant function analysis to data on urinary catecholamines and metabolites. Arch Gen Psychiatry 1978 0.75
93 Catecholamine measures for diagnosis and treatment of patients with depressive disorders. J Clin Psychiatry 1980 0.75
94 Urinary mhpg in anorexia nervosa patients with and without a concomitant major depressive disorder. J Psychiatr Res 1984 0.75
95 Platelet monoamine oxidase activity in psychiatric disorders: the application of a technique for the isolation of free platelet mitochondria from relatively small blood samples. J Psychiatr Res 1981 0.75
96 Proceedings: Comparative properties of soluble and particulate catechol-O-methyl transferase from rat red blood cell: preliminary observations. Psychopharmacol Bull 1974 0.75
97 Comparative properties of soluble and particulate catechol-O-methyl transferases from rat red blood cells: preliminary observations. Adv Biochem Psychopharmacol 1974 0.75
98 The effects of lithium on norepinephrine turnover and metabolism: basic and clinical studies. J Nerv Ment Dis 1974 0.75
99 Further studies of the effects of morphine on the levels of MHPG-SO4 in rat brain. Neuropharmacology 1979 0.75
100 Platelet MAO activity in anorexia nervosa patients with and without a major depressive disorder. Am J Psychiatry 1984 0.75
101 Acute and delayed effects of corticotropin-releasing hormone on dopamine activity in man. Biol Psychiatry 1994 0.75
102 Catecholamine metabolism in affective disorders. II. Norepinephrine, normetanephrine, epinephrine, metanephrine, and VMA excretion in hypomanic patients. Arch Gen Psychiatry 1969 0.75
103 Elevated platelet MAO activity in schizophrenia-related depressive disorders. Am J Psychiatry 1978 0.75
104 The dexamethasone suppression test (DST) and platelet monoamine oxidase (MAO) activity as predictors of psychosis in depression. Biol Psychiatry 1986 0.75
105 Platelet MAO activity: relationships to clinical and psychometric variables. Schizophr Bull 1980 0.75
106 Neuropharmacological studies of mood disorders. Proc Annu Meet Am Psychopathol Assoc 1972 0.75
107 Antidepressant drugs. Science 1966 0.75
108 Urinary 3-methoxy-4-hydroxyphenylglycol and the depression-type score as predictors of differential responses to antidepressants. J Clin Psychopharmacol 1991 0.75
109 Effect of cortical spreading depression on norepinephrine-H3 metabolism in brain stem. Experientia 1968 0.75
110 Noradrenergic activity during the transition from depression to mania. Lancet 1971 0.75
111 Effects of the d- and l-isomers of amphetamine on the levels of 3-methoxy-4-hydroxyphenylglycol sulfate in whole rat brain and rat brain regions. Biochem Pharmacol 1978 0.75
112 Effects of acute and chronic administration of desmethylimipramine on the content of norepinephrine and other monoamines in the rat brain. Biochem Pharmacol 1973 0.75
113 Possible pathophysiological mechanisms in subtypes of unipolar depressive disorders based on differences in urinary MHPG levels [proceedings]. Psychopharmacol Bull 1981 0.75
114 Effects of short-and long-term administration of tricyclic antidepressants and lithium on norepinephrine turnover in brain. Pharmakopsychiatr Neuropsychopharmakol 1976 0.75
115 Guidelines for therapeutic monitoring of tricyclic antidepressant plasma levels. Ther Drug Monit 1979 0.75
116 Toward a biochemical classification of depressive disorders, VII: urinary free cortisol and urinary MHPG in depressions. Am J Psychiatry 1983 0.75
117 Platelet monoamine oxidase activity and deficit syndrome schizophrenia. Psychiatry Res 1995 0.75
118 Affective disorders and norepinephrine pharmacology. Int Psychiatry Clin 1969 0.75
119 Properties of catechol-O-methyl transferase in soluble and particulate preparations from rat red blood cells. Biochem Pharmacol 1976 0.75
120 Some biochemical correlates of panic attacks with agoraphobia and their response to a new treatment. J Clin Psychopharmacol 1984 0.75
121 The effects of lthium salts on the turnover and metabolism of norepinephrine in rat brain. Psychopharmacologia 1969 0.75
122 Norepinephrine pools in rat brain: differences in turnover rates and pathways of metabolism. Science 1971 0.75
123 Norepinephrine metabolism after short- and long-term administration of tricyclic antidepressant drugs and electroconvulsive shock. Adv Biochem Psychopharmacol 1975 0.75
124 Turnover and metabolism of norepinephrine in rat brain after 72 hours on a D-deprivation island. Psychopharmacologia 1972 0.75
125 Neurochemical studies of the affective disorders: the pharmacological bridge. Am J Psychiatry 1970 0.75
126 An improved method for the recovery of mitochondrial monoamine oxidase from human platelets using colchicine and nitrogen decompression. Biochem Med 1981 0.75
127 The effects of acute and chronic morphine administration on the levels of 3-methoxy-4-hydroxphenylglycol sulfate in rat brain. Res Commun Chem Pathol Pharmacol 1975 0.75