Published in Humangenetik on January 01, 1966
Hurler's syndrome: a genetic study of clones in cell culture with particular reference to the Lyon hypothesis. J Exp Med (1967) 1.63
Gene loss in human teratomas. Proc Natl Acad Sci U S A (1969) 1.15
Development of a nonselective technique for studying 2, 6, diaminopurine resistance in an established murine cell line. Genetics (1968) 1.12
Mammalian X-chromosome inactivation. Annu Rev Genet (1983) 4.89
The DNMT3B DNA methyltransferase gene is mutated in the ICF immunodeficiency syndrome. Proc Natl Acad Sci U S A (1999) 4.13
Glucose-6-phosphate dehydrogenase mosaicism: utilization as a cell marker in the study of leiomyomas. Science (1965) 3.02
Association of fragile X syndrome with delayed replication of the FMR1 gene. Cell (1993) 2.52
Polymerase chain reaction-aided genomic sequencing of an X chromosome-linked CpG island: methylation patterns suggest clonal inheritance, CpG site autonomy, and an explanation of activity state stability. Proc Natl Acad Sci U S A (1990) 2.51
The occurrence of new mutants in the X-linked recessive Lesch-Nyhan disease. Am J Hum Genet (1976) 2.51
Clonal origin of chronic myelocytic leukemia in man. Proc Natl Acad Sci U S A (1967) 2.48
Half chromatid mutations: transmission in humans? Am J Hum Genet (1975) 2.38
Methylation analysis of CGG sites in the CpG island of the human FMR1 gene. Hum Mol Genet (1992) 2.32
Transformation with DNA from 5-azacytidine-reactivated X chromosomes. Proc Natl Acad Sci U S A (1982) 2.22
Demethylation of specific sites in the 5' region of the inactive X-linked human phosphoglycerate kinase gene correlates with the appearance of nuclease sensitivity and gene expression. Mol Cell Biol (1988) 2.07
Apparent Hela cell contamination of human heteroploid cell lines. Nature (1968) 1.94
Genetic markers as tracers in cell culture. Natl Cancer Inst Monogr (1967) 1.87
Isolation of a cDNA clone for human X-linked 3-phosphoglycerate kinase by use of a mixture of synthetic oligodeoxyribonucleotides as a detection probe. Proc Natl Acad Sci U S A (1983) 1.71
The applications of genetic mosaicism to developmental problems. Annu Rev Genet (1971) 1.65
Glucose-6-phosphate dehydrogenase mosaicism: ito;ozatopm om tje study of hair follicle variegation. Ann Hum Genet (1971) 1.64
Lesch-Nyhan syndrome: rapid detection of heterozygotes by use of hair follicles. Science (1971) 1.64
Escape from gene silencing in ICF syndrome: evidence for advanced replication time as a major determinant. Hum Mol Genet (2000) 1.61
X-linkage of steroid sulphatase in the mouse is evidence for a functional Y-linked allele. Nature (1985) 1.60
Orthopedic disorders in patients with Down's syndrome. Orthop Clin North Am (1981) 1.60
Glucose-6 phosphate dehydrogenase mosaicism: utilization as a tracer in the study of the development of hair root cells. Ann Hum Genet (1969) 1.57
Analysis of CpG suppression in methylated and nonmethylated species. Proc Natl Acad Sci U S A (1992) 1.46
5-Azacytidine-induced reactivation of the human X chromosome-linked PGK1 gene is associated with a large region of cytosine demethylation in the 5' CpG island. Proc Natl Acad Sci U S A (1990) 1.45
Role of late replication timing in the silencing of X-linked genes. Hum Mol Genet (1996) 1.41
Developmental implications of multiple tissue studies in glucose-6-phosphate dehydrogenase-deficient heterozygotes. Proc Natl Acad Sci U S A (1968) 1.37
Mammalian X-chromosome inactivation. Adv Hum Genet (1976) 1.33
A variable domain of delayed replication in FRAXA fragile X chromosomes: X inactivation-like spread of late replication. Proc Natl Acad Sci U S A (1997) 1.32
Regional localization of the human factor IX gene by molecular hybridization. Hum Genet (1983) 1.28
Clonal origin for individual Burkitt tumours. Lancet (1970) 1.27
Answer to criticism of Morton and Lalouel. Am J Hum Genet (1977) 1.24
Evidence for two functional X chromosomes in human oocytes. Cell Differ (1972) 1.23
Satellite 2 methylation patterns in normal and ICF syndrome cells and association of hypomethylation with advanced replication. Hum Genet (2001) 1.20
Glucose-6-phosphate dehydrogenase mosaicism as a tracer in the study of hereditary multiple trichoepithelioma. Am J Hum Genet (1966) 1.19
Reactivation of XIST in normal fibroblasts and a somatic cell hybrid: abnormal localization of XIST RNA in hybrid cells. Proc Natl Acad Sci U S A (1998) 1.17
Development of a nonselective technique for studying 2, 6, diaminopurine resistance in an established murine cell line. Genetics (1968) 1.12
Hemimethylation and hypersensitivity are early events in transcriptional reactivation of human inactive X-linked genes in a hamster x human somatic cell hybrid. Mol Cell Biol (1992) 1.12
Comparison of transformation efficiency of human active and inactive X-chromosomal DNA. Nature (1983) 1.11
Linkage of the steroid sulfatase gene to the sex-reversed mutation in the mouse. Genetics (1987) 1.10
High rate of recombination and double crossovers in the mouse pseudoautosomal region during male meiosis. Proc Natl Acad Sci U S A (1987) 1.09
A potentially critical Hpa II site of the X chromosome-linked PGK1 gene is unmethylated prior to the onset of meiosis of human oogenic cells. Proc Natl Acad Sci U S A (1992) 1.07
Reverse replication timing for the XIST gene in human fibroblasts. Hum Mol Genet (1995) 1.07
Allele-specific replication timing in imprinted domains: absence of asynchrony at several loci. Hum Mol Genet (1995) 1.07
Two functional X chromosomes in human fetal oocytes. Exp Cell Res (1973) 1.06
Multiple cell origin of hereditary neurofibromas. N Engl J Med (1971) 1.06
Evidence for a dosage effect at the X-linked steroid sulfatase locus in human tissues. Am J Hum Genet (1983) 1.05
Cystathionine synthase activity in human lymphocytes: induction by phytohemagglutinin. J Clin Invest (1972) 1.04
Expression of two X-linked genes in human hair follicles of double heterozygotes. Proc Natl Acad Sci U S A (1971) 1.03
Replication of the mouse sex chromosomes early in the S period. Cytogenetics (1970) 1.03
Ontogeny of X-chromosome inactivation in the female germ line. Exp Cell Res (1975) 1.02
Molecular cytological differentiation of active from inactive X domains in interphase: implications for X chromosome inactivation. Cytogenet Cell Genet (1989) 1.02
HGPRT activity changes in preimplantation mouse embryos. Nature (1978) 1.01
Mammalian X chromosome inactivation: testing the hypothesis of transcriptional control. Somat Cell Mol Genet (1986) 1.00
Evidence for X-linkage of steroid sulfatase in the mouse: steroid sulfatase levels in oocytes of XX and XO mice. Genetics (1983) 1.00
A chicken transferrin gene in transgenic mice escapes X-chromosome inactivation. Science (1987) 0.95
Effect of chronologic age on induction of cystathionine synthase, uroporphyrinogen I synthase, and glucose-6-phosphate dehydrogenase activities in lymphocytes. Proc Natl Acad Sci U S A (1981) 0.94
A fluorescent in situ hybridization analysis of X chromosome pairing in early human female meiosis. Hum Genet (1994) 0.94
High-frequency reactivation of X-linked genes in Chinese hamster X human hybrid cells. Somat Cell Mol Genet (1987) 0.93
Chromatin structure of active and inactive human X chromosomes. Nucleic Acids Res (1984) 0.93
Xrep, a plasmid-stimulating X chromosomal sequence bearing similarities to the BK virus replication origin and viral enhancers. Nucleic Acids Res (1986) 0.92
Very late DNA replication in the human cell cycle. Proc Natl Acad Sci U S A (1998) 0.92
Analysis of replication timing at the FRA10B and FRA16B fragile site loci. Chromosome Res (2000) 0.91
Glucose-6-phosphate dehydrogenase mosaicism for studying the development of blood cell precursors. Nature (1969) 0.91
5-Azadeoxycytidine-induced chromatin remodeling of the inactive X-linked HPRT gene promoter occurs prior to transcription factor binding and gene reactivation. J Biol Chem (1997) 0.91
X chromosome inactivation in cells from an individual heterozygous for two X-linked genes. Nat New Biol (1972) 0.90
Dosage of the Sts gene in the mouse. Am J Hum Genet (1986) 0.90
DNA methylation in transcriptional repression of two differentially expressed X-linked genes, GPC3 and SYBL1. Proc Natl Acad Sci U S A (1999) 0.89
A two step model for mammalian X-chromosome inactivation. Prog Clin Biol Res (1985) 0.87
Cytological evidence for an inactive X chromosome in murine oogonia. Cytogenet Cell Genet (1980) 0.87
X-chromosome inactivation and selection in somatic cells. Fed Proc (1976) 0.87
X chromosome inactivaton and SV40 transformation of mammalian cells. Somatic Cell Genet (1979) 0.86
Chromosomal fragile sites: molecular test of the delayed-replication model. Cold Spring Harb Symp Quant Biol (1993) 0.84
Evidence for two active X chromosomes in a human XXY triploid. Humangenetik (1975) 0.84
Patterns of cellular proliferation in normal and tumor cell populations. Am J Pathol (1977) 0.84
Chromosome painting analysis of early oogenesis in human trisomy 18. Cytogenet Cell Genet (1995) 0.84
Transformation of Hprt gene with sperm DNA. Somatic Cell Genet (1983) 0.84
Chromatin structure of active and inactive human X-linked phosphoglycerate kinase gene. Somat Cell Mol Genet (1986) 0.84
Nucleotide sequence of the 3' nuclease-sensitive region of the human phosphoglycerate kinase 1 (PGK1) gene. Genomics (1991) 0.84
An analysis of meiotic pairing in trisomy 21 oocytes using fluorescent in situ hybridization. Cytogenet Cell Genet (1998) 0.83
Isoenzyme stability in human heteroploid cell lines. Exp Cell Res (1970) 0.82
Chromosomal aberrations in 2 embryos from the same mother. An embryo with B trisomy and another with triploidy and associated cleft lip. Am J Obstet Gynecol (1968) 0.82
A study of metabolic cooperation utilizing human mutant fibroblasts. Exp Cell Res (1971) 0.82
Analysis of a paracentric inversion in human oocytes: nonhomologous pairing in pachytene. Hum Genet (1999) 0.81
Analysis of inactive X chromosome structure by in situ nick translation. Chromosoma (1985) 0.80
Identification of HeLa cell glucose 6-phosphate dehydrogenase. Biochem Genet (1971) 0.80
Homocystinuria: heterozygote detection using phytohemagglutinin-stimulated lymphocytes. J Clin Invest (1973) 0.80
Inactivation and reactivation of sex-linked steroid sulfatase gene in murine cell culture. Somat Cell Mol Genet (1988) 0.80
Hyperploidy effect of lymphocyte extract on fibroblasts in vitro. Nature (1966) 0.80
The value of the California Psychological Inventory in predicting medical students' career choice. Med Educ (1985) 0.79
Switching off blocks of genes. Nature (1983) 0.79
Fetal development of the multiple forms of rat hexokinase. Biochem Med (1972) 0.78
Absence of methylation at HpaII sites in three human genomic tRNA sequences. Nucleic Acids Res (1990) 0.78
Mapping of human autosomal phosphoglycerate kinase sequence to chromosome 19. Somat Cell Mol Genet (1986) 0.77
Down's syndrome. Study of carbohydrate metabolism. Acta Endocrinol (Copenh) (1974) 0.75
Cystathionine synthase activity in human leukocyte cultures. Birth Defects Orig Artic Ser (1973) 0.75
Studies of tumor cell origins in mosaics. Prog Clin Biol Res (1982) 0.75
Patterns of protein synthesis at the onset of oogenesis in the mouse. Differentiation (1982) 0.75
The utilization of the human phosphoglycerate kinase gene in the investigation of X-chromosome inactivation. Horiz Biochem Biophys (1986) 0.75
Thoughts on the action committees of the American society of human genetics. Am J Hum Genet (1988) 0.75
Transformation of the Hprt gene with DNA from spermatogenic cells. Implications for the evolution of X chromosome inactivation. Chromosoma (1984) 0.75
Hypoxanthine guanine phosphoribosyl transferase expression in early mouse development. Basic Life Sci (1978) 0.75