Published in Science on October 01, 1965
Evidence for a monoclonal origin of human atherosclerotic plaques. Proc Natl Acad Sci U S A (1973) 4.72
Etiology and pathogenesis of uterine leiomyomas: a review. Environ Health Perspect (2003) 2.98
Immunochemical identification of intermediate-sized filaments in human neoplastic cells. A diagnostic aid for the surgical pathologist. Am J Pathol (1981) 2.94
Clonal origin of chronic myelocytic leukemia in man. Proc Natl Acad Sci U S A (1967) 2.48
Hematopoiesis is not clonal in healthy elderly women. Blood (2008) 1.95
Gracefully ageing at 50, X-chromosome inactivation becomes a paradigm for RNA and chromatin control. Nat Rev Mol Cell Biol (2011) 1.66
Tracing the tumor lineage. Mol Oncol (2010) 1.56
Developmental implications of multiple tissue studies in glucose-6-phosphate dehydrogenase-deficient heterozygotes. Proc Natl Acad Sci U S A (1968) 1.37
Clonal characteristics of fibrous plaques and fatty streaks from human aortas. Am J Pathol (1975) 1.37
No evidence that skewing of X chromosome inactivation patterns is transmitted to offspring in humans. J Clin Invest (2008) 1.30
Clonal architecture of normal and atherosclerotic aorta: implications for atherogenesis and vascular development. Am J Pathol (1998) 1.22
Immortalization of primary human smooth muscle cells. Proc Natl Acad Sci U S A (1992) 1.21
Monoclonality of smooth muscle cells in human atherosclerosis. Am J Pathol (1997) 1.21
Warner-Lambert/Parke-Davis Award Lecture. Viral pathogenesis of atherosclerosis. Impact of molecular mimicry and viral genes. Am J Pathol (1991) 1.19
Glucose-6-phosphate dehydrogenase mosaicism as a tracer in the study of hereditary multiple trichoepithelioma. Am J Hum Genet (1966) 1.19
Gene loss in human teratomas. Proc Natl Acad Sci U S A (1969) 1.15
RFLP of the X chromosome-linked glucose-6-phosphate dehydrogenase locus in blacks. Am J Hum Genet (1988) 1.08
Disseminated peritoneal leiomyomatosis. Clonality analysis by X chromosome inactivation and cytogenetics of a clinically benign smooth muscle proliferation. Am J Pathol (1997) 1.07
Aryl 4-monooxygenase and cytochrome P-450 in the aorta: possible role in atherosclerosis. Proc Natl Acad Sci U S A (1976) 1.06
Polymorphic X-chromosome inactivation of the human TIMP1 gene. Am J Hum Genet (1999) 1.05
The clonal origin and clonal evolution of epithelial tumours. Int J Exp Pathol (2000) 1.04
A skewed view of X chromosome inactivation. J Clin Invest (2008) 1.01
Glucose-6-phosphate dehydrogenase deficiency. Postgrad Med J (1994) 0.99
Paracrine activation of WNT/β-catenin pathway in uterine leiomyoma stem cells promotes tumor growth. Proc Natl Acad Sci U S A (2013) 0.98
Clonal characteristics of cutaneous scars and implications for atherogenesis. Am J Pathol (1981) 0.96
Mapping of human chromosomal regions related to neoplasia: evidence from chromosomes 1 and 17. Proc Natl Acad Sci U S A (1977) 0.96
Population study of 1311 C/T polymorphism of Glucose 6 Phosphate Dehydrogenase gene in Pakistan - an analysis of 715 X-chromosomes. BMC Genet (2009) 0.95
Focal smooth muscle proliferation in the aortic intima produced by an initiation-promotion sequence. Proc Natl Acad Sci U S A (1985) 0.94
The human atherosclerotic plaque. Am J Pathol (1977) 0.92
Clonal analysis of human tumors with M27 beta, a highly informative polymorphic X chromosomal probe. J Clin Invest (1992) 0.90
Analysis of gene alterations of mitochondrial DNA D-loop regions to determine breast cancer clonality. Br J Cancer (2012) 0.87
Expression profiling of uterine leiomyomata cytogenetic subgroups reveals distinct signatures in matched myometrium: transcriptional profilingof the t(12;14) and evidence in support of predisposing genetic heterogeneity. Hum Mol Genet (2012) 0.87
Ovarian steroids, stem cells and uterine leiomyoma: therapeutic implications. Hum Reprod Update (2014) 0.87
The clonal characteristics of human aortic intima. Comparison with fatty streaks and normal media. Am J Pathol (1983) 0.86
Clonal characteristics in layers of human atherosclerotic plaques. A study of the selection hypothesis of monoclonality. Am J Pathol (1978) 0.85
Patterns of cellular proliferation in normal and tumor cell populations. Am J Pathol (1977) 0.84
Passenger mutations as a marker of clonal cell lineages in emerging neoplasia. Semin Cancer Biol (2010) 0.83
Stro-1/CD44 as putative human myometrial and fibroid stem cell markers. Fertil Steril (2015) 0.83
Platelet-derived growth factor C is upregulated in human uterine fibroids and regulates uterine smooth muscle cell growth. Biol Reprod (2009) 0.83
Tissue-specific stem cells in the myometrium and tumor-initiating cells in leiomyoma. Biol Reprod (2014) 0.83
Clonal mapping of the human aorta. Relationship of monoclonal characteristics, lesion thickness, and age in normal intima and atherosclerotic lesions. Am J Pathol (1987) 0.81
Multicolor lineage tracing methods and intestinal tumors. J Gastroenterol (2013) 0.81
Epidemiological and genetic clues for molecular mechanisms involved in uterine leiomyoma development and growth. Hum Reprod Update (2015) 0.80
Anecdotal, historical and critical commentaries on genetics. Rudolph Virchow and the genetic basis of somatic ecology. Genetics (1999) 0.79
Endocrinology of uterine fibroids: steroid hormones, stem cells, and genetic contribution. Curr Opin Obstet Gynecol (2015) 0.78
Tumor Evolution: Linear, Branching, Neutral or Punctuated? Biochim Biophys Acta (2017) 0.77
Forty-five years of cell-cycle genetics. Mol Biol Cell (2015) 0.76
Phenotypic heterogeneity within clones of fetal human cells. Am J Hum Genet (1981) 0.75
Preleukemia: One name, many meanings. Leukemia (2016) 0.75
Converting of Myometrial Stem Cells to Tumor-Initiating Cells: Mechanism of Uterine Fibroid Development. Cell Stem Cells Regen Med (2016) 0.75
Human genetic markers as tracers of tumour histogenesis. J Clin Pathol Suppl (R Coll Pathol) (1974) 0.75
Endocrine-disrupting chemicals and uterine fibroids. Fertil Steril (2016) 0.75
Methemoglobin reduction and the inactive X hypothesis. Am J Hum Genet (1966) 0.75
2016 Victor A. McKusick Leadership Award Introduction: Stanley Gartler. Am J Hum Genet (2017) 0.75
Mammalian X-chromosome inactivation. Annu Rev Genet (1983) 4.89
The DNMT3B DNA methyltransferase gene is mutated in the ICF immunodeficiency syndrome. Proc Natl Acad Sci U S A (1999) 4.13
Parthenogenic origin of benign ovarian teratomas. N Engl J Med (1975) 2.53
Association of fragile X syndrome with delayed replication of the FMR1 gene. Cell (1993) 2.52
The occurrence of new mutants in the X-linked recessive Lesch-Nyhan disease. Am J Hum Genet (1976) 2.51
Polymerase chain reaction-aided genomic sequencing of an X chromosome-linked CpG island: methylation patterns suggest clonal inheritance, CpG site autonomy, and an explanation of activity state stability. Proc Natl Acad Sci U S A (1990) 2.51
Clonal origin of chronic myelocytic leukemia in man. Proc Natl Acad Sci U S A (1967) 2.48
Half chromatid mutations: transmission in humans? Am J Hum Genet (1975) 2.38
Methylation analysis of CGG sites in the CpG island of the human FMR1 gene. Hum Mol Genet (1992) 2.32
Transformation with DNA from 5-azacytidine-reactivated X chromosomes. Proc Natl Acad Sci U S A (1982) 2.22
Proteolytic activation of the influenza virus hemagglutinin: The structure of the cleavage site and the enzymes involved in cleavage. Virology (1981) 2.13
Demethylation of specific sites in the 5' region of the inactive X-linked human phosphoglycerate kinase gene correlates with the appearance of nuclease sensitivity and gene expression. Mol Cell Biol (1988) 2.07
Psoriasis: is the impairment to a patient's life cumulative? J Eur Acad Dermatol Venereol (2010) 2.01
Apparent Hela cell contamination of human heteroploid cell lines. Nature (1968) 1.94
Genetic markers as tracers in cell culture. Natl Cancer Inst Monogr (1967) 1.87
Marburg virus gene 4 encodes the virion membrane protein, a type I transmembrane glycoprotein. J Virol (1993) 1.85
Chemosensitivity testing of human tumors using a microplate adenosine triphosphate luminescence assay: clinical correlation for cisplatin resistance of ovarian carcinoma. Cancer Res (1995) 1.83
Propionate oxidation in Escherichia coli: evidence for operation of a methylcitrate cycle in bacteria. Arch Microbiol (1997) 1.77
Isolation of a cDNA clone for human X-linked 3-phosphoglycerate kinase by use of a mixture of synthetic oligodeoxyribonucleotides as a detection probe. Proc Natl Acad Sci U S A (1983) 1.71
The applications of genetic mosaicism to developmental problems. Annu Rev Genet (1971) 1.65
Glucose-6-phosphate dehydrogenase mosaicism: ito;ozatopm om tje study of hair follicle variegation. Ann Hum Genet (1971) 1.64
Lesch-Nyhan syndrome: rapid detection of heterozygotes by use of hair follicles. Science (1971) 1.64
Escape from gene silencing in ICF syndrome: evidence for advanced replication time as a major determinant. Hum Mol Genet (2000) 1.61
X-linkage of steroid sulphatase in the mouse is evidence for a functional Y-linked allele. Nature (1985) 1.60
Further evidence for post-meiotic origin of teratomas in the human female. Ann Hum Genet (1970) 1.59
Glucose-6 phosphate dehydrogenase mosaicism: utilization as a tracer in the study of the development of hair root cells. Ann Hum Genet (1969) 1.57
Analysis of CpG suppression in methylated and nonmethylated species. Proc Natl Acad Sci U S A (1992) 1.46
Localization of the intrachain disulfide bonds of the envelope glycoprotein 71 from Friend murine leukemia virus. Eur J Biochem (1992) 1.45
5-Azacytidine-induced reactivation of the human X chromosome-linked PGK1 gene is associated with a large region of cytosine demethylation in the 5' CpG island. Proc Natl Acad Sci U S A (1990) 1.45
Role of late replication timing in the silencing of X-linked genes. Hum Mol Genet (1996) 1.41
Estimating distances from the centromere by means of benign ovarian teratomas in man. Ann Hum Genet (1976) 1.40
Developmental implications of multiple tissue studies in glucose-6-phosphate dehydrogenase-deficient heterozygotes. Proc Natl Acad Sci U S A (1968) 1.37
Mammalian X-chromosome inactivation. Adv Hum Genet (1976) 1.33
A variable domain of delayed replication in FRAXA fragile X chromosomes: X inactivation-like spread of late replication. Proc Natl Acad Sci U S A (1997) 1.32
The carboxyterminus of the hemagglutinin-neuraminidase of Newcastle disease virus is exposed at the surface of the viral envelope. Virus Res (1984) 1.31
Regional localization of the human factor IX gene by molecular hybridization. Hum Genet (1983) 1.28
Clonal origin for individual Burkitt tumours. Lancet (1970) 1.27
The carbohydrates of mouse hepatitis virus (MHV) A59: structures of the O-glycosidically linked oligosaccharides of glycoprotein E1. EMBO J (1984) 1.24
Answer to criticism of Morton and Lalouel. Am J Hum Genet (1977) 1.24
Evidence for two functional X chromosomes in human oocytes. Cell Differ (1972) 1.23
Two genetically distinct methyl-coenzyme M reductases in Methanobacterium thermoautotrophicum strain Marburg and delta H. Eur J Biochem (1990) 1.22
Satellite 2 methylation patterns in normal and ICF syndrome cells and association of hypomethylation with advanced replication. Hum Genet (2001) 1.20
Glucose-6-phosphate dehydrogenase mosaicism as a tracer in the study of hereditary multiple trichoepithelioma. Am J Hum Genet (1966) 1.19
Reactivation of XIST in normal fibroblasts and a somatic cell hybrid: abnormal localization of XIST RNA in hybrid cells. Proc Natl Acad Sci U S A (1998) 1.17
Elastase 1 and chymotrypsin B in pancreatic juice and feces. Clin Biochem (1989) 1.15
Fermentation of 4-aminobutyrate by Clostridium aminobutyricum: cloning of two genes involved in the formation and dehydration of 4-hydroxybutyryl-CoA. Arch Microbiol (2000) 1.15
Gene loss in human teratomas. Proc Natl Acad Sci U S A (1969) 1.15
Development of a nonselective technique for studying 2, 6, diaminopurine resistance in an established murine cell line. Genetics (1968) 1.12
Hemimethylation and hypersensitivity are early events in transcriptional reactivation of human inactive X-linked genes in a hamster x human somatic cell hybrid. Mol Cell Biol (1992) 1.12
Comparison of transformation efficiency of human active and inactive X-chromosomal DNA. Nature (1983) 1.11
Linkage of the steroid sulfatase gene to the sex-reversed mutation in the mouse. Genetics (1987) 1.10
Pyruvate: ferredoxin oxidoreductase from the sulfate-reducing Archaeoglobus fulgidus: molecular composition, catalytic properties, and sequence alignments. Arch Microbiol (1995) 1.10
The absence of inactivation at two autosomal loci. Humangenetik (1966) 1.10
High rate of recombination and double crossovers in the mouse pseudoautosomal region during male meiosis. Proc Natl Acad Sci U S A (1987) 1.09
Structures and functions of four anabolic 2-oxoacid oxidoreductases in Methanobacterium thermoautotrophicum. Eur J Biochem (1997) 1.08
Methylcitrate synthase from Aspergillus nidulans: implications for propionate as an antifungal agent. Mol Microbiol (2000) 1.08
A potentially critical Hpa II site of the X chromosome-linked PGK1 gene is unmethylated prior to the onset of meiosis of human oogenic cells. Proc Natl Acad Sci U S A (1992) 1.07
Allele-specific replication timing in imprinted domains: absence of asynchrony at several loci. Hum Mol Genet (1995) 1.07
Reverse replication timing for the XIST gene in human fibroblasts. Hum Mol Genet (1995) 1.07
Salt dependence, kinetic properties and catalytic mechanism of N-formylmethanofuran:tetrahydromethanopterin formyltransferase from the extreme thermophile Methanopyrus kandleri. Eur J Biochem (1992) 1.07
Two functional X chromosomes in human fetal oocytes. Exp Cell Res (1973) 1.06
The involvement of coenzyme A esters in the dehydration of (R)-phenyllactate to (E)-cinnamate by Clostridium sporogenes. Eur J Biochem (2000) 1.06
The cleavage site of the hemagglutinin of fowl plague virus. Virology (1982) 1.06
Multiple cell origin of hereditary neurofibromas. N Engl J Med (1971) 1.06
Studies on the sterol-binding capacity of human pancreatic elastase 1. Gastroenterology (1991) 1.05
Evidence for a dosage effect at the X-linked steroid sulfatase locus in human tissues. Am J Hum Genet (1983) 1.05
The energy conserving N5-methyltetrahydromethanopterin:coenzyme M methyltransferase complex from Methanobacterium thermoautotrophicum is composed of eight different subunits. Eur J Biochem (1995) 1.05
The heterodisulfide reductase from Methanobacterium thermoautotrophicum contains sequence motifs characteristic of pyridine-nucleotide-dependent thioredoxin reductases. Eur J Biochem (1994) 1.05
Cystathionine synthase activity in human lymphocytes: induction by phytohemagglutinin. J Clin Invest (1972) 1.04
Purification and properties of N5-methyltetrahydromethanopterin:coenzyme M methyltransferase from Methanobacterium thermoautotrophicum. Eur J Biochem (1993) 1.03
Expression of two X-linked genes in human hair follicles of double heterozygotes. Proc Natl Acad Sci U S A (1971) 1.03
Isolation and characterization of polyferredoxin from Methanobacterium thermoautotrophicum. The mvhB gene product of the methylviologen-reducing hydrogenase operon. FEBS Lett (1992) 1.03
Replication of the mouse sex chromosomes early in the S period. Cytogenetics (1970) 1.03
A family of secreted mucins from the parasitic nematode Toxocara canis bears diverse mucin domains but shares similar flanking six-cysteine repeat motifs. J Biol Chem (2000) 1.03
Molecular cytological differentiation of active from inactive X domains in interphase: implications for X chromosome inactivation. Cytogenet Cell Genet (1989) 1.02
Ontogeny of X-chromosome inactivation in the female germ line. Exp Cell Res (1975) 1.02
Oligosaccharides at individual glycosylation sites in glycoprotein 71 of Friend murine leukemia virus. Eur J Biochem (1990) 1.02
HGPRT activity changes in preimplantation mouse embryos. Nature (1978) 1.01
Glycoproteins of friend murine leukemia virus: separation and NH2-terminal amino acid sequences of gp69 and gp71. J Virol (1982) 1.01
Mammalian X chromosome inactivation: testing the hypothesis of transcriptional control. Somat Cell Mol Genet (1986) 1.00
Evidence for X-linkage of steroid sulfatase in the mouse: steroid sulfatase levels in oocytes of XX and XO mice. Genetics (1983) 1.00
Heterogeneity of chemosensitivity in human breast carcinoma: use of an adenosine triphosphate (ATP) chemiluminescence assay. Eur J Surg Oncol (1993) 0.98
Succinate-ethanol fermentation in Clostridium kluyveri: purification and characterisation of 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA delta 3-delta 2-isomerase. Arch Microbiol (1994) 0.98
F420H2: quinone oxidoreductase from Archaeoglobus fulgidus. Characterization of a membrane-bound multisubunit complex containing FAD and iron-sulfur clusters. Eur J Biochem (1994) 0.98
Purification of glutaryl-CoA dehydrogenase from Pseudomonas sp., an enzyme involved in the anaerobic degradation of benzoate. Arch Microbiol (1993) 0.97
Comparators, study duration, outcome measures and sponsorship in therapeutic trials of psoriasis: update of the EDEN Psoriasis Survey 2001-2006. Br J Dermatol (2009) 0.97
The invariant chains of mouse class II antigens: biochemical properties and molecular relationship. Eur J Immunol (1984) 0.97
Culture of cells from the urine and bladder washings of adults. Somatic Cell Genet (1976) 0.97
Tungstate can substitute for molybdate in sustaining growth of Methanobacterium thermoautotrophicum. Identification and characterization of a tungsten isoenzyme of formylmethanofuran dehydrogenase. Arch Microbiol (1994) 0.97
Analysis of the pre-S2 N- and O-linked glycans of the M surface protein from human hepatitis B virus. J Biol Chem (1999) 0.96
Function of methylcobalamin: coenzyme M methyltransferase isoenzyme II in Methanosarcina barkeri. Arch Microbiol (1993) 0.96
Cloning, sequencing and expression of the gene encoding the coenzyme B12-dependent 2-methyleneglutarate mutase from Clostridium barkeri in Escherichia coli. Eur J Biochem (1994) 0.96
Purification and properties of N5,N10-methylenetetrahydromethanopterin reductase (coenzyme F420-dependent) from the extreme thermophile Methanopyrus kandleri. Arch Microbiol (1991) 0.96
Characterization of a heme-dependent catalase from Methanobrevibacter arboriphilus. Appl Environ Microbiol (2001) 0.96
Human benign ovarian teratomas: chromosomal and electrophoretic enzyme studies. Birth Defects Orig Artic Ser (1978) 0.95
Primary structure of cyclohydrolase (Mch) from Methanobacterium thermoautotrophicum (strain Marburg) and functional expression of the mch gene in Escherichia coli. Eur J Biochem (1996) 0.95
A chicken transferrin gene in transgenic mice escapes X-chromosome inactivation. Science (1987) 0.95
Effect of chronologic age on induction of cystathionine synthase, uroporphyrinogen I synthase, and glucose-6-phosphate dehydrogenase activities in lymphocytes. Proc Natl Acad Sci U S A (1981) 0.94
Ovarian teratomas: cytologic data. Cytogenet Cell Genet (1976) 0.94