Published in Nature on March 23, 1968
Effect of zinc and cadmium on guinea-pig complement. Immunology (1974) 0.81
The C3-activator system: an alternate pathway of complement activation. J Exp Med (1971) 7.07
C3 proactivator convertase and its mode of action. J Exp Med (1972) 6.94
High-resolution record of Northern Hemisphere climate extending into the last interglacial period. Nature (2004) 6.44
Orbital and millennial Antarctic climate variability over the past 800,000 years. Science (2007) 5.10
Bicarbonate conductance and pH regulatory capability of cystic fibrosis transmembrane conductance regulator. Proc Natl Acad Sci U S A (1994) 3.21
Lysis of erythrocytes by complement in the absence of antibody. J Exp Med (1970) 3.19
A functional MRI study of human amygdala responses to facial expressions of fear versus anger. Emotion (2001) 3.15
Paroxysmal nocturnal hemoglobinuria. Hemolysis initiated by the C3 activator system. N Engl J Med (1972) 2.91
The role of properdin in the alternate pathway of complement activation. J Exp Med (1974) 2.77
Bacteriophage T7 DNA replication in vitro. Stimulation of DNA synthesis by T7 RNA polymerase. J Biol Chem (1980) 2.73
Alternative pathway of complement: recruitment of precursor properdin by the labile C3/C5 convertase and the potentiation of the pathway. J Exp Med (1976) 2.66
Differential prefrontal cortex and amygdala habituation to repeatedly presented emotional stimuli. Neuroreport (2001) 2.60
Atmospheric oxidation capacity sustained by a tropical forest. Nature (2008) 2.34
Differential response in the human amygdala to racial outgroup vs ingroup face stimuli. Neuroreport (2000) 2.29
Binding of staphylococcal enterotoxin A to accessory cells is a requirement for its ability to activate human T cells. J Immunol (1988) 2.28
Robotic system for biopsy and therapy of breast lesions in a high-field whole-body magnetic resonance tomography unit. Invest Radiol (2000) 2.14
Alternative pathway of complement: demonstration and characterization of initiating factor and its properdin-independent function. J Exp Med (1976) 2.13
A molecular concept of the properdin pathway. Proc Natl Acad Sci U S A (1976) 2.09
Image reconstruction for echo planar imaging with nonequidistant k-space sampling. Magn Reson Med (1992) 2.09
CT of the head by use of reduced current and kilovoltage: relationship between image quality and dose reduction. AJNR Am J Neuroradiol (2000) 2.05
Southern Ocean sea-ice extent, productivity and iron flux over the past eight glacial cycles. Nature (2006) 1.94
VII. Fibrolipoma of Stomach: Removal by Resection of Stomach; Convalescence Complicated by Tetany. Ann Surg (1905) 1.92
The alternative pathway of complement activation. Adv Immunol (1976) 1.87
Consumption of human complement components by complexes of IgG with protein A of Staphylococcus aureus. Immunochemistry (1973) 1.86
cAMP-independent activation of CFTR Cl channels by the tyrosine kinase inhibitor genistein. Am J Physiol (1995) 1.69
Studies on the activation of mouse bone marrow-derived macrophages by the macrophage cytotoxicity factor (MCF). Eur J Immunol (1976) 1.69
Global air pollution crossroads over the Mediterranean. Science (2002) 1.68
The serine protease nature of the C3 and C5 convertases of the classical and alternative complement pathways. Scand J Immunol (1976) 1.67
Detection of circulating immune complexes in patients with glomerulonephritis. Kidney Int (1977) 1.66
Application of C1-esterase inhibitor during reperfusion of ischemic myocardium: dose-related beneficial versus detrimental effects. Circulation (2001) 1.64
A serum factor in chronic hypocomplementemic hephritis distinct from immunoglobulins and activating the alternate pathway of complement. J Exp Med (1974) 1.63
The effect of SV40 infection on DNA synthesis in cercopithecus kidney cells. Virology (1966) 1.63
Gender and age differences in the prevalence of specific fears and phobias. Behav Res Ther (1996) 1.60
Defective function of the cystic fibrosis-causing missense mutation G551D is recovered by genistein. Am J Physiol (1999) 1.57
Prostaglandin and thromboxane synthesis in a pure macrophage population and the inhibition, by E-type prostaglandins, of chemiluminescence. FEBS Lett (1978) 1.55
In vivo magnetic resonance imaging and spectroscopy of humans with a 4 T whole-body magnet. NMR Biomed (1990) 1.52
Cerebral blood flow in subjects with social phobia during stressful speaking tasks: a PET study. Am J Psychiatry (2001) 1.52
Truncated splice variant PGC-1α4 is not associated with exercise-induced human muscle hypertrophy. Acta Physiol (Oxf) (2014) 1.52
The induction of macrophage spreading by factor B of the properdin system. J Exp Med (1979) 1.50
The C-terminus of complement regulator Factor H mediates target recognition: evidence for a compact conformation of the native protein. Clin Exp Immunol (2006) 1.50
Alternative pathway of complement: nonenzymatic, reversible transition of precursor to active properdin. J Immunol (1977) 1.47
Rotavirus infection as cause of tacrolimus elevation in solid-organ-transplanted children. Pediatr Transplant (2001) 1.45
ROBITOM-robot for biopsy and therapy of the mamma. Biomed Tech (Berl) (2002) 1.45
Type 1 fimbriae deliver an LPS- and TLR4-dependent activation signal to CD14-negative cells. Mol Microbiol (2001) 1.42
Expression of the receptor for complement C5a (CD88) is up-regulated on reactive astrocytes, microglia, and endothelial cells in the inflamed human central nervous system. Am J Pathol (1997) 1.41
Inhibition of terminal complement complex formation and cell lysis by monoclonal antibodies. Complement Inflamm (1991) 1.41
[Experimental ultrasound angioplasty: in vitro resolution of thrombi]. Z Kardiol (1995) 1.40
Survey on controversies in airway management among anesthesiologists in the UK, Austria and Switzerland. Minerva Anestesiol (2012) 1.39
Bioelectrical impedance analysis as a predictor of survival in patients with human immunodeficiency virus infection. J Acquir Immune Defic Syndr Hum Retrovirol (1995) 1.38
Microsatellite instability in sporadic colorectal cancer is not an independent prognostic factor. Br J Cancer (1999) 1.36
Identification of virus-induced proteins in cells productively infected with simian virus 40. J Virol (1972) 1.35
Neutrophil recruitment, chemokine receptors, and resistance to mucosal infection. J Leukoc Biol (2001) 1.30
Regulation of macrophage migration by products of the complement system. Proc Natl Acad Sci U S A (1979) 1.29
The iso-renin angiotensin systems in extrarenal tissue. Clin Exp Pharmacol Physiol (1976) 1.28
[Comparative investigations of microstructures in degeneration of semilunar cartilages (author's transl)]. Z Orthop Ihre Grenzgeb (1974) 1.27
Flavonoids stimulate Cl conductance of human airway epithelium in vitro and in vivo. Am J Physiol (1998) 1.27
Ursodeoxycholic acid in primary biliary cirrhosis: results of a controlled double-blind trial. Gastroenterology (1989) 1.27
Glucagon-like peptide 1 abolishes the postprandial rise in triglyceride concentrations and lowers levels of non-esterified fatty acids in humans. Diabetologia (2006) 1.26
Isolation of variants of lymphocytopathic retroviruses from the peripheral blood and cerebrospinal fluid of patients with ARC or AIDS. J Med Virol (1986) 1.26
Differential effects of temperature on the nuclear and plasma membranes of lymphoid cells. A study by freeze-etch electron microscopy. Biochim Biophys Acta (1974) 1.24
Intracoronary application of C1 esterase inhibitor improves cardiac function and reduces myocardial necrosis in an experimental model of ischemia and reperfusion. Circulation (1997) 1.23
Escherichia coli P fimbriae utilize the Toll-like receptor 4 pathway for cell activation. Mol Microbiol (2001) 1.23
Functionally active complement proteins C6 and C7 detected in C6- and C7-deficient individuals. Clin Exp Immunol (1991) 1.22
Nephritic factor: its structure and function and its relationship to initiating factor of the alternative pathway. Scand J Immunol (1976) 1.21
Evidence from nitrogen fertilisation in the forests of Germany. Environ Pollut (1988) 1.21
Complement utilization by guinea pig 1 and 2-immunoglobulins through the C3 activator system. J Immunol (1971) 1.20
A single bout of exercise activates matrix metalloproteinase in human skeletal muscle. J Appl Physiol (1985) (2007) 1.19
Peptidoglycan cross-linking and teichoic acid attachment in Streptococcus pneumoniae. J Bacteriol (1985) 1.19
Production and release of peptidoglycan and wall teichoic acid polymers in pneumococci treated with beta-lactam antibiotics. J Bacteriol (1984) 1.17
Radiotherapy with and without cisplatin in bladder cancer. Int J Radiat Oncol Biol Phys (1990) 1.17
Release of trapped marker from liposomes by the action of purified complement components. Proc Natl Acad Sci U S A (1969) 1.16
Clustering of ligand on the surface of a particle enhances adhesion to receptor-bearing cells. J Biol Chem (1988) 1.16
TLR- and CXCR1-dependent innate immunity: insights into the genetics of urinary tract infections. Eur J Clin Invest (2008) 1.15
Complement activation in septic baboons detected by neoepitope-specific assays for C3b/iC3b/C3c, C5a and the terminal C5b-9 complement complex (TCC). Clin Exp Immunol (1993) 1.15
Role of macrophages in malaria: O2 metabolite production and phagocytosis by splenic macrophages during lethal Plasmodium berghei and self-limiting Plasmodium yoelii infection in mice. Infect Immun (1984) 1.15
Efficient expression of CFTR function with adeno-associated virus vectors that carry shortened CFTR genes. Proc Natl Acad Sci U S A (1998) 1.14
Identification and characterization of the complement C5a anaphylatoxin receptor on human astrocytes. J Immunol (1995) 1.14
Physiological effects of fast oscillating magnetic field gradients. J Comput Assist Tomogr (1991) 1.12
Activated complement C3: a potentially novel predictor of progressive IgA nephropathy. Kidney Int (1997) 1.11
Tacrolimus and minidose methotrexate for prevention of acute graft-versus-host disease after HLA-mismatched marrow or blood stem cell transplantation. Bone Marrow Transplant (1999) 1.11
Angiotensin and cell growth: a link to cardiovascular hypertrophy? J Hypertens (1991) 1.11
FGF5 as an oncogenic factor in human glioblastoma multiforme: autocrine and paracrine activities. Oncogene (2008) 1.11
T-cell cytotoxicity and amplification of the cytotoxic reaction by macrophages. Transplant Rev (1973) 1.11
VEGF-A splice variants and related receptor expression in human skeletal muscle following submaximal exercise. J Appl Physiol (1985) (2005) 1.11
Anion selectivity of apical membrane conductance of Calu 3 human airway epithelium. Pflugers Arch (1999) 1.11
The pattern of protein synthesis in SV40-infected CV-1 cells. Int J Cancer (1970) 1.10
Probing the human receptor for C5a anaphylatoxin with site-directed antibodies. Identification of a potential ligand binding site on the NH2-terminal domain. J Immunol (1993) 1.10
The Indian Ocean experiment: widespread air pollution from South and Southeast Asia. Science (2001) 1.09
Control of arachidonic acid accumulation in bone marrow-derived macrophages by acyltransferases. J Biol Chem (1981) 1.09
Measurement of spin-transfer observables in p p-->Lambda Lambda at 1.637 GeV/c. Phys Rev Lett (2002) 1.09
Functional neuroanatomical correlates of electrodermal activity: a positron emission tomographic study. Psychophysiology (1998) 1.09
Fibroblast growth factor receptor 3-IIIc mediates colorectal cancer growth and migration. Br J Cancer (2010) 1.09
Tacrolimus and minidose methotrexate for prevention of acute graft-versus-host disease after matched unrelated donor marrow transplantation. Blood (1996) 1.08
C5a suppresses the production of IL-12 by IFN-gamma-primed and lipopolysaccharide-challenged human monocytes. J Immunol (1999) 1.07
Macrophage cytotoxicity factor. A product of in vitro sensitized thymus-dependent cells. Eur J Immunol (1973) 1.07
Congenital sodium diarrhea is an autosomal recessive disorder of sodium/proton exchange but unrelated to known candidate genes. Gastroenterology (2000) 1.07
Caspase-14: analysis of gene structure and mRNA expression during keratinocyte differentiation. Biochem Biophys Res Commun (2000) 1.07
Structural determinants for activation and block of CFTR-mediated chloride currents by apigenin. Am J Physiol Cell Physiol (2000) 1.07