Published in J Physiol on August 01, 1968
Central sensitization: implications for the diagnosis and treatment of pain. Pain (2010) 6.88
Tactile sensibility in the human hand: relative and absolute densities of four types of mechanoreceptive units in glabrous skin. J Physiol (1979) 3.71
The sensory neurons of touch. Neuron (2013) 2.03
Evidence for two different heat transduction mechanisms in nociceptive primary afferents innervating monkey skin. J Physiol (1995) 1.97
Calcium signaling in intact dorsal root ganglia: new observations and the effect of injury. Anesthesiology (2010) 1.49
The sensitization of high threshold mechanoreceptors with myelinated axons by repeated heating. J Physiol (1977) 1.36
Unresponsive afferent nerve fibres in the sural nerve of the rat. J Physiol (1991) 1.17
Functional role of unmyelinated tactile afferents in human hairy skin: sympathetic response and perceptual localization. Exp Brain Res (2007) 1.17
Selective responsiveness of polymodal nociceptors of the rabbit ear to capsaicin, bradykinin and ultra-violet irradiation. J Physiol (1987) 1.01
Two classes of slowly adapting mechanoreceptor fibres in reptile cutaneous nerve. J Physiol (1971) 0.98
Fast-conducting mechanoreceptors contribute to withdrawal behavior in normal and nerve injured rats. Pain (2014) 0.95
Primary afferent depolarization and flexion reflexes produced by radiant heat stimulation of the skin. J Physiol (1971) 0.94
Sensory receptors in the sheep's foot. J Physiol (1973) 0.93
Pain mechanisms: a commentary on concepts and issues. Prog Neurobiol (2011) 0.91
Task-dependent modulation of primary afferent depolarization in cervical spinal cord of monkeys performing an instructed delay task. J Neurophysiol (2009) 0.90
Characteristics, specificity, and efferent control of frog cutaneous cold receptors. J Physiol (1974) 0.89
The conduction velocities of peripheral nerve fibres conveying sensations of warming and cooling. J Neurol Neurosurg Psychiatry (1988) 0.88
A new method for demonstration of central effects of analgesic agents in man. J Neurol Neurosurg Psychiatry (1984) 0.88
Biophysical and functional consequences of receptor-mediated nerve fiber transformation. Biophys J (1997) 0.85
Local antinociception induced by endothelin-1 in the hairy skin of the rat's back. J Pain (2009) 0.83
HCN1 and HCN2 in Rat DRG neurons: levels in nociceptors and non-nociceptors, NT3-dependence and influence of CFA-induced skin inflammation on HCN2 and NT3 expression. PLoS One (2012) 0.83
Early postnatal loss of heat sensitivity among cutaneous myelinated nociceptors in Swiss-Webster mice. J Neurophysiol (2010) 0.82
Spatial summation of thermal sensations depends on skin type and skin sensitivity. Exp Brain Res (2009) 0.81
Analysis of trigeminal nerve disorders after oral and maxillofacial intervention. Head Face Med (2010) 0.77
Electrophysiology of the afferent innervation of the penis of the domestic ram. J Physiol (1978) 0.77
The fundamental unit of pain is the cell. Pain (2013) 0.76
Disturbances in affective touch in hereditary sensory & autonomic neuropathy type III. Int J Psychophysiol (2014) 0.75
Pain mechanisms: a new theory. Science (1965) 24.47
Touch, pain and tickling: an electro-physiological investigation on cutaneous sensory nerves. J Physiol (1939) 13.11
Action currents in single afferent nerve fibres elicited by stimulation of the skin of the toad and the cat. J Physiol (1952) 4.61
An analysis of fibre diameter and receptor characteristics of myelinated cutaneous afferent fibres in cat. J Physiol (1960) 3.41
A quantitative study of cutaneous receptors and afferent fibres in the cat and rabbit. J Physiol (1967) 3.19
Myelinated afferent fibres responding specifically to noxious stimulation of the skin. J Physiol (1967) 3.09
Cutaneous mechanoreceptors with afferent C fibres. J Physiol (1960) 3.02
On the nature of vibration receptors in the hind limb of the cat. J Physiol (1961) 2.96
Cutaneous heat and cold receptors with slowly conducting (C) afferent fibres. Q J Exp Physiol Cogn Med Sci (1959) 2.74
Afferent impulses in cutaneous sensory nerves in human subjects. J Neurophysiol (1960) 2.51
[Afferent impulses from the skin of extremities of cats in thermal and mechanical stimulation]. Pflugers Arch (1959) 2.23
The specificity of afferent cutaneous C fibres in mammals. Acta Physiol Scand (1960) 1.75
Relation of peripheral nerve fiber size and sensation in man. Arch Neurol (1960) 1.73
Multiple temperature-sensitive spots innervated by single nerve fibers. Science (1967) 1.12
On the nature of cutaneous sensory mechanisms. Brain (1962) 1.09
TEMPERATURE DISCRIMINATION IN THE SKIN. Nature (1964) 0.93
[Pain impulses in thermal stimulation]. Acta Physiol Scand (1954) 0.84
Response of cutaneous sensory units with unmyelinated fibers to noxious stimuli. J Neurophysiol (1969) 4.68
Myelinated afferent fibres responding specifically to noxious stimulation of the skin. J Physiol (1967) 3.09
Correlations between neuronal morphology and electrophysiological features in the rodent superficial dorsal horn. J Physiol (2002) 2.49
Spinal neurons specifically excited by noxious or thermal stimuli: marginal zone of the dorsal horn. J Neurophysiol (1970) 2.26
Spinal termination of functionally identified primary afferent neurons with slowly conducting myelinated fibers. J Comp Neurol (1979) 2.15
Dynamic properties of mechanoreceptors with unmyelinated (C) fibers. J Neurophysiol (1971) 2.04
Relationship of substance P to afferent characteristics of dorsal root ganglion neurones in guinea-pig. J Physiol (1997) 2.01
Central projections of identified, unmyelinated (C) afferent fibers innervating mammalian skin. Science (1986) 1.99
Primate cutaneous sensory units with unmyelinated (C) afferent fibers. J Neurophysiol (1977) 1.95
Reexamination of the dorsal root projection to the spinal dorsal horn including observations on the differential termination of coarse and fine fibers. J Comp Neurol (1979) 1.80
Amovement receptor of the small intestine. J Physiol (1966) 1.75
Morphological features of functionally defined neurons in the marginal zone and substantia gelatinosa of the spinal dorsal horn. J Comp Neurol (1979) 1.74
Excitation of marginal and substantia gelatinosa neurons in the primate spinal cord: indications of their place in dorsal horn functional organization. J Comp Neurol (1978) 1.67
Adrenergic excitation of cutaneous pain receptors induced by peripheral nerve injury. Science (1991) 1.55
Is ATP a central synaptic mediator for certain primary afferent fibers from mammalian skin? Proc Natl Acad Sci U S A (1984) 1.47
Sensitization of high threshold receptors with unmyelinated (C) afferent fibers. Prog Brain Res (1976) 1.37
Differences in Ca2+ channels governing generation of miniature and evoked excitatory synaptic currents in spinal laminae I and II. J Neurosci (1998) 1.30
Sensory fibers of the pelvic nerve innervating the Rat's urinary bladder. J Neurophysiol (2000) 1.26
Comparison of primary afferent and glutamate excitation of neurons in the mammalian spinal dorsal horn. J Neurosci (1988) 1.20
Calcitonin gene-related peptide immunoreactivity and afferent receptive properties of dorsal root ganglion neurones in guinea-pigs. J Physiol (2002) 1.15
Sympathetic activity and the systemic circulation in the spinal cat. J Physiol (1965) 1.14
Characteristics of viscerosympathetic reflexes in the spinal cat. Am J Physiol (1966) 1.14
Expression of alpha2-adrenergic receptors in rat primary afferent neurones after peripheral nerve injury or inflammation. J Physiol (1999) 1.11
Sensory receptors with unmyelinated (C) fibers innervating the skin of the rabbit's ear. J Neurophysiol (1985) 1.11
Antidromically evoked responses from sympathetic preganglionic neurones. J Physiol (1965) 1.09
Adenosine inhibition of synaptic transmission in the substantia gelatinosa. J Neurophysiol (1994) 1.09
ATP modulation of synaptic transmission in the spinal substantia gelatinosa. J Neurosci (1995) 1.04
Fine structure of myelinated mechanical nociceptor endings in cat hairy skin. J Comp Neurol (1981) 0.99
A comparison of four tests for assessing the pain sensitivity of different subjects and test areas. Pain (1977) 0.95
Synaptic ultrastructure of functionally and morphologically characterized neurons of the superficial spinal dorsal horn of cat. J Neurosci (1989) 0.93
Synaptic complexes formed by functionally defined primary afferent units with fine myelinated fibers. J Comp Neurol (1982) 0.90
Regeneration of cutaneous afferent unmyelinated (C) fibers after transection. J Neurophysiol (1985) 0.89
Selective excitation of neurons in the mammalian spinal dorsal horn by aspartate and glutamate in vitro: correlation with location and excitatory input. Brain Res (1985) 0.89
Morphology and synaptic relationships of physiologically identified low-threshold dorsal root axons stained with intra-axonal horseradish peroxidase in the cat and monkey. J Neurophysiol (1984) 0.88
Effects of partial nerve injury on the responses of C-fiber polymodal nociceptors to adrenergic agonists. Brain Res (1997) 0.87
Pain. Curr Opin Genet Dev (1999) 0.86
Contributions of arachidonic acid derivatives and substance P to the sensitization of cutaneous nociceptors. J Neurophysiol (1990) 0.86
The Use of Change in Capacity to Record Cardiac Volume in Human Subjects. Science (1949) 0.86
Primate cutaneous receptors with unmyelinated (C) fibres and their projection to the substantia gelatinosa. J Physiol (Paris) (1977) 0.84
Functional and morphological features of neurons in the midline region of the caudal spinal cord of the cat. Brain Res (1985) 0.84
In situ hybridization using 32P labelled oligodeoxyribonucleotides for the cellular localisation of mRNA in neuronal and endocrine tissue. An analysis of procedural variables. Histochemistry (1988) 0.83
Effects of nerve injury on sympathetic excitation of A delta mechanical nociceptors. J Neurophysiol (1995) 0.82
Sensory experiences in man evoked by intraneural electrical stimulation of intact cutaneous afferent fibers. Exp Brain Res (1981) 0.82
Differential termination of large-diameter and small-diameter primary afferent fibers in the spinal dorsal gray matter as indicated by labeling with horseradish peroxidase. Neurosci Lett (1977) 0.82
Synaptic mediation from cutaneous mechanical nociceptors. J Neurophysiol (1994) 0.82
Reorganization of primary afferent nerve terminals in the spinal dorsal horn of the primate caudal to anterolateral chordotomy. J Comp Neurol (1988) 0.79
Sympathectomy induces adrenergic excitability of cutaneous C-fiber nociceptors. J Neurophysiol (1996) 0.79
Cutaneous sensory receptors. J Clin Neurophysiol (1994) 0.79
Microelectrode arrays for stimulation of neural slice preparations. J Neurosci Methods (1997) 0.79
Chemical factors in the sensitization of cutaneous nociceptors. Prog Brain Res (1988) 0.78
Species-specific expression of cholecystokinin messenger RNA in rodent dorsal root ganglia. Brain Res Mol Brain Res (1990) 0.78
Neurons in ventrobasal region of cat thalamus selectively responsive to noxious mechanical stimulation. J Neurophysiol (1983) 0.78
Criteria for evaluating spinal cord regeneration experiments. Surg Neurol (1980) 0.77
Criteria for evaluating spinal cord regeneration experiments. Exp Neurol (1980) 0.77
Is pain a specific sensation? J Psychiatr Res (1971) 0.77
Getting a line on pain: is it mediated by dedicated pathways? Nat Neurosci (1998) 0.76
Somatic sensation: transfer and processing of information. 1. Peripheral receptors. Electroencephalogr Clin Neurophysiol (1969) 0.76
Failure of acupuncture to produce localized analgesia. Pain (1977) 0.75
Acupuncture analgesia of the skin in relation to the traditional meridian map. J Physiol (1975) 0.75
Distribution of primary afferent fibers within the sacrococcygeal dorsal horn: an autoradiographic study. J Comp Neurol (1979) 0.75
Afferent basis of nociception and pain: evidence from the characteristics of sensory receptors and their projections to the spinal dorsal horn. Res Publ Assoc Res Nerv Ment Dis (1980) 0.75
Neuronal geometry. Science (1982) 0.75
N-methyl-D-aspartate (NMDA) depolarizes glutamate-insensitive neurones in the superficial dorsal horn. Acta Physiol Scand (1992) 0.75
Differential L-glutamate responsiveness among superficial dorsal horn neurons. J Neurophysiol (1994) 0.75
[Study on sympathetic medullary reflexes]. Actual Neurophysiol (Paris) (1968) 0.75
Failure of sympathetic stimulation to affect responsiveness of rabbit polymodal nociceptors. J Neurophysiol (1985) 0.75