Published in Science on March 12, 1971
Increased collagen synthesis by scleroderma skin fibroblasts in vitro: a possible defect in the regulation or activation of the scleroderma fibroblast. J Clin Invest (1974) 3.32
Lymphokine stimulation of collagen accumulation. J Clin Invest (1976) 2.94
Ultrastructural identification of extension aminopropeptides of type I and III collagens in human skin. Proc Natl Acad Sci U S A (1981) 2.03
Myofibroblasts in murine cutaneous fibrosis originate from adiponectin-positive intradermal progenitors. Arthritis Rheumatol (2015) 1.85
Connective tissue synthesis by scleroderma skin fibroblasts in cell culture. J Exp Med (1972) 1.78
Scleroderma-like properties of skin from caveolin-1-deficient mice: implications for new treatment strategies in patients with fibrosis and systemic sclerosis. Cell Cycle (2011) 1.52
Co-localization of transforming growth factor beta 2 with alpha 1(I) procollagen mRNA in tissue sections of patients with systemic sclerosis. J Clin Invest (1990) 1.36
Eosinophilic fasciitis. Case report and review of the literature. Ann Rheum Dis (1977) 1.23
Chronic cutaneous graft-versus-host disease in man. Am J Pathol (1978) 1.21
Raised serum hyaluronate levels in scleroderma: an effect of growth factor induced activation of connective tissue cells? Ann Rheum Dis (1985) 1.20
Aminoterminal extension peptides from type I procollagen normalize excessive collagen synthesis of scleroderma fibroblasts. Arch Dermatol Res (1978) 1.01
Scleroderma fibroblasts: some aspects of in vitro assessment of collagen synthesis. Arch Dermatol Res (1981) 0.89
Dendritic cells maintain dermal adipose-derived stromal cells in skin fibrosis. J Clin Invest (2016) 0.83
The Role of Adipocytes in Tissue Regeneration and Stem Cell Niches. Annu Rev Cell Dev Biol (2016) 0.78
Origin of fibrosing cells in systemic sclerosis. Curr Opin Rheumatol (2015) 0.75
Scleroderma (systemic sclerosis): classification, subsets and pathogenesis. J Rheumatol (1988) 16.45
Antitumor effect and potentiation of cytotoxic drugs activity in human cancer cells by ZD-1839 (Iressa), an epidermal growth factor receptor-selective tyrosine kinase inhibitor. Clin Cancer Res (2000) 3.95
Experimental emphysema induced with purified human neutrophil elastase: tissue localization of the instilled protease. Am Rev Respir Dis (1977) 2.41
Inhibition of growth factor production and angiogenesis in human cancer cells by ZD1839 (Iressa), a selective epidermal growth factor receptor tyrosine kinase inhibitor. Clin Cancer Res (2001) 2.29
Ultrastructural identification of extension aminopropeptides of type I and III collagens in human skin. Proc Natl Acad Sci U S A (1981) 2.03
Cellular infiltrates in scleroderma skin. Arthritis Rheum (1977) 1.96
Immunochemistry, genuine size and tissue localization of collagen VI. Eur J Biochem (1984) 1.91
Antiangiogenic and antitumor activity of anti-epidermal growth factor receptor C225 monoclonal antibody in combination with vascular endothelial growth factor antisense oligonucleotide in human GEO colon cancer cells. Clin Cancer Res (2000) 1.82
Collagen fibril formation during embryogenesis. Proc Natl Acad Sci U S A (1983) 1.68
Antitumor activity of sequential treatment with topotecan and anti-epidermal growth factor receptor monoclonal antibody C225. Clin Cancer Res (1999) 1.66
Inhibition of mTOR pathway by everolimus cooperates with EGFR inhibitors in human tumours sensitive and resistant to anti-EGFR drugs. Br J Cancer (2008) 1.62
A phase II study of biweekly oxaliplatin plus infusional 5-fluorouracil and folinic acid (FOLFOX-4) as first-line treatment of advanced gastric cancer patients. Br J Cancer (2005) 1.61
Variability in collagen and fibronectin synthesis by scleroderma fibroblasts in primary culture. J Invest Dermatol (1981) 1.58
Pseudoxanthoma elasticum and mitral-valve prolapse. N Engl J Med (1982) 1.41
Circulating Fc gamma receptor-specific autoantibodies in localized and systemic scleroderma. J Am Acad Dermatol (1995) 1.40
Collagen fibrillogenesis in human skin. Ann N Y Acad Sci (1985) 1.38
Connective tissue synthesis by cultured scleroderma fibroblasts. I. In vitro collagen synthesis by normal and scleroderma dermal fibroblasts. Arthritis Rheum (1976) 1.38
Normolipemic tendon and tuberous xanthomas. J Am Acad Dermatol (1981) 1.33
Werner's syndrome. Am J Med (1973) 1.29
Skin capillary changes in early systemic scleroderma. Electron microscopy and "in vitro" autoradiography with tritiated thymidine. Arch Dermatol (1976) 1.27
Alteration of subcutaneous tissue in systemic scleroderma. Arch Dermatol (1972) 1.27
Structure and macromolecular organization of type VI collagen. Ann N Y Acad Sci (1985) 1.26
Changes in plasma lipids and lipoproteins during isotretinoin therapy for acne. N Engl J Med (1985) 1.15
Antitumor activity of combined blockade of epidermal growth factor receptor and protein kinase A. J Natl Cancer Inst (1996) 1.13
Collagen in the cellular and fibrotic stages of scleroderma. Arthritis Rheum (1978) 1.12
Glycosaminoglycans in scleroderma and scleredema. J Invest Dermatol (1972) 1.12
Mucinous adventitial cysts of the popliteal artery in an 11-year-old girl. Surgery (1973) 1.10
Correlation of the histologic observations and operative findings in patients with chronic pancreatitis. Surg Gynecol Obstet (1971) 1.09
Generalized morphea. I. Histology of the dermis and subcutaneous tissue. Arch Dermatol (1972) 1.08
Metastatic Crohn's disease. J Am Acad Dermatol (1984) 1.07
The pathophysiology of scleroderma. Int J Dermatol (1977) 1.06
Variegate porphyria (mixed porphyria). Arch Dermatol (1967) 1.05
Scleroderma. A model for fibrosis. Arch Dermatol (1983) 1.05
Altered expression of angiopoietins and Tie2 endothelium receptor in psoriasis. J Invest Dermatol (2001) 1.05
Abnormalities of connective tissue components in lesional and non-lesional tissue of patients with pseudoxanthoma elasticum. Arch Dermatol Res (1993) 1.03
Scleroderma, eosinophilia, and diffuse fasciitis. Arch Dermatol (1978) 1.03
Antitumor activity of combined treatment of human cancer cells with ionizing radiation and anti-epidermal growth factor receptor monoclonal antibody C225 plus type I protein kinase A antisense oligonucleotide. Clin Cancer Res (2000) 1.02
Capillary alterations in scleroderma. J Am Acad Dermatol (1980) 1.02
Induction of skin fibrosis and autoantibodies by infusion of immunocompetent cells from tight skin mice into C57BL/6 Pa/Pa mice. J Autoimmun (1993) 1.01
The RIalpha subunit of protein kinase A (PKA) binds to Grb2 and allows PKA interaction with the activated EGF-receptor. Oncogene (1997) 1.00
Chemical synthesis of the dermis in scleroderma. Proc Soc Exp Biol Med (1967) 0.99
Biliary cystadenoma. Report of a case and review of the literature. Arch Surg (1971) 0.99
Ultrastructure of cutaneous cellular infiltrates in scleroderma. Arch Dermatol (1977) 0.96
Roentgenographic features of thymolipoma. Am J Roentgenol Radium Ther Nucl Med (1973) 0.95
Clinical, pathologic, and immunopathologic manifestations of the toxic oil syndrome. Analysis of fourteen cases. J Am Acad Dermatol (1988) 0.95
Lymphokine/monokine inhibition of fibroblast proliferation and collagen production: role in progressive systemic sclerosis (PSS). J Invest Dermatol (1984) 0.94
Gemcitabine combined with continuous infusion 5-fluorouracil in advanced and symptomatic pancreatic cancer: a clinical benefit-oriented phase II study. Br J Cancer (2000) 0.94
Dermal glycosaminoglycans in psoriasis. J Invest Dermatol (1970) 0.93
Systemic scleroderma: A review of organ systems. Int J Dermatol (1975) 0.92
Immunofluorescence analysis of collagen, fibronectin, and basement membrane protein in scleroderma skin. J Invest Dermatol (1980) 0.92
Mucin-producing carcinoma of the breast. Tissue culture, histochemical and electron microscopic study. Cancer (1966) 0.91
Unusual cutaneous carcinoma with features of small cell (oat cell-like) and squamous cell carcinomas. A variant of malignant Merkel cell neoplasm. Am J Dermatopathol (1982) 0.91
Immunoelectron microscopy of type III collagen in normal and scleroderma skin. J Invest Dermatol (1980) 0.91
Scleredema. Arch Dermatol (1965) 0.91
Increased procollagen mRNA levels in scleroderma skin fibroblasts. J Invest Dermatol (1983) 0.90
Diseases of the dermis. J Am Acad Dermatol (1990) 0.90
Ultrastructural localization of fibronectin to different anatomic structures of human skin. J Histochem Cytochem (1984) 0.90
Self reactive repertoire of tight skin mouse: immunochemical and molecular characterization of anti-topoisomerase I autoantibodies. Autoimmunity (1991) 0.90
Immunochemistry of elastotic material in sun-damaged skin. J Invest Dermatol (1986) 0.89
Identification of collagen fibrils in scleroderma skin. J Invest Dermatol (1988) 0.89
Enzastaurin inhibits tumours sensitive and resistant to anti-EGFR drugs. Br J Cancer (2008) 0.89
Fractionation of glycosaminoglycans from psoriatic skin. J Invest Dermatol (1970) 0.89
[3H]Thymidine labeling of dermal endothelial cells in scleroderma. J Invest Dermatol (1977) 0.88
Basement membrane proteins, interstitial collagens, and fibronectin in neurofibroma. J Invest Dermatol (1985) 0.88
Immunopathogenesis of scleroderma--evolving concepts. Mt Sinai J Med (2001) 0.87
The clinical significance of cutaneous xanthomas. Postgrad Med J (1970) 0.87
Culturing keratinocytes and fibroblasts in a three-dimensional mesh results in epidermal differentiation and formation of a basal lamina-anchoring zone. J Invest Dermatol (1993) 0.87
A novel MDM2 anti-sense oligonucleotide has anti-tumor activity and potentiates cytotoxic drugs acting by different mechanisms in human colon cancer. Int J Cancer (2000) 0.86
Oral administration of a novel taxane, an antisense oligonucleotide targeting protein kinase A, and the epidermal growth factor receptor inhibitor Iressa causes cooperative antitumor and antiangiogenic activity. Clin Cancer Res (2001) 0.86
Basement membrane proteins produced by Schwann cells and in neurofibromatosis. Ann N Y Acad Sci (1986) 0.86
Cooperative inhibition of renal cancer growth by anti-epidermal growth factor receptor antibody and protein kinase A antisense oligonucleotide. J Natl Cancer Inst (1998) 0.86
Amino and carboxyl propeptides in bone collagen fibrils during embryogenesis. Cell Tissue Res (1987) 0.86
Non-collagenous proteins of human dermis. J Invest Dermatol (1967) 0.86
Collagen synthesis in scleroderma: selection of fibroblast populations during subcultures. Arch Dermatol Res (1985) 0.85
Secretion of elastin in the embryonic chick aorta as visualized by immunoelectron microscopy. Coll Relat Res (1984) 0.85
Preclinical and phase I study of oxaliplatin and topotecan in combination in human cancer. Ann Oncol (2002) 0.85
Collagen synthesis by scleroderma fibroblasts. Ann N Y Acad Sci (1985) 0.84
Collagen fibrillogenesis in a three-dimensional fibroblast cell culture system. Cell Tissue Res (1993) 0.84
Angiogenic and signalling proteins correlate with sensitivity to sequential treatment in renal cell cancer. Br J Cancer (2013) 0.83
Preliminary report on the antimycotic effect of topical thiabendazole "in vivo". Curr Ther Res Clin Exp (1965) 0.83
The Hughes-Stovin syndrome. Case report. Radiology (1974) 0.82
Association of elastin with oxytalan fibers of the dermis and with extracellular microfibrils of cultured skin fibroblasts. J Histochem Cytochem (1986) 0.82
Glycosaminoglycans of skin and urine in pseudoxanthoma elasticum: evidence for chondroitin 6-sulfate alteration. Clin Chim Acta (1986) 0.82
Immuno electron microscopic studies on cells synthesizing elastin. Connect Tissue Res (1981) 0.82
Therapeutic integration of signal transduction targeting agents and conventional anti-cancer treatments. Endocr Relat Cancer (2004) 0.81
Immunoelectron microscopy of proteodermatan sulfate in human mid-dermis. Connect Tissue Res (1985) 0.81
Generalized morphea. II. Electron microscopy of collagen, cells, and the subcutaneous tissue. Arch Dermatol (1972) 0.81
Two novel human anti-ErbB2 immunoagents are active on trastuzumab-resistant tumours. Br J Cancer (2010) 0.81
Collagen fibrillogenesis: a mechanism of structural biology. J Invest Dermatol (1986) 0.81
Alterations in dermal collagen in ultraviolet irradiated hairless mice. J Invest Dermatol (1989) 0.81
Growth inhibition of human colon carcinoma cells by combinations of anti-epidermal growth factor-related growth factor antisense oligonucleotides. Clin Cancer Res (1996) 0.81
Human dermal glycosaminoglycans and aging. Biochim Biophys Acta (1972) 0.81
Wilms' tumor associated with venous thrombosis and consumption coagulopathy. Am J Dis Child (1972) 0.81
Familial hyperlipoproteinemia type 3. Arch Dermatol (1969) 0.80
Failure of dimethyl sulfoxide in the treatment of scleroderma. Arch Dermatol (1977) 0.80
Mycophenolic acid in the treatment of psoriasis: long-term administration. Arch Dermatol (1977) 0.80