Published in J Exp Med on March 01, 1971
Short chain fatty acids in the human colon. Gut (1981) 3.49
Isolation of Methanobrevibacter smithii from human feces. Appl Environ Microbiol (1982) 2.37
Downwind update--a discourse on matters gaseous. West J Med (1986) 2.23
Fermentation by the human large intestine microbial community in an in vitro semicontinuous culture system. Appl Environ Microbiol (1981) 2.21
Incidence of methanogenic bacteria in a sigmoidoscopy population: an association of methanogenic bacteria and diverticulosis. Gut (1986) 2.13
Sulphate reducing bacteria and hydrogen metabolism in the human large intestine. Gut (1993) 2.05
Pan-genome of the dominant human gut-associated archaeon, Methanobrevibacter smithii, studied in twins. Proc Natl Acad Sci U S A (2011) 1.96
Role of pH in production of hydrogen from carbohydrates by colonic bacterial flora. Studies in vivo and in vitro. J Clin Invest (1981) 1.93
Methane excretion in man--a study of breath, flatus, and faeces. Gut (1985) 1.88
Archaea and their potential role in human disease. Infect Immun (2003) 1.86
Carbohydrate fermentation in the human colon and its relation to acetate concentrations in venous blood. J Clin Invest (1985) 1.77
Studies on breath methane: the effect of ethnic origins and lactulose. Gut (1980) 1.63
Breath methane and large bowel cancer risk in contrasting African populations. Gut (1988) 1.50
Stability of Methanobrevibacter smithii populations in the microbial flora excreted from the human large bowel. Appl Environ Microbiol (1983) 1.48
Methane production during lactulose breath test is associated with gastrointestinal disease presentation. Dig Dis Sci (2003) 1.46
Acetate production from hydrogen and [13C]carbon dioxide by the microflora of human feces. Appl Environ Microbiol (1988) 1.44
Methanogenic bacteria from human dental plaque. Appl Environ Microbiol (1988) 1.37
Abundance and diversity of mucosa-associated hydrogenotrophic microbes in the healthy human colon. ISME J (2011) 1.35
The first 1000 cultured species of the human gastrointestinal microbiota. FEMS Microbiol Rev (2014) 1.34
Methane and the gastrointestinal tract. Dig Dis Sci (2009) 1.24
Role of dietary sulphate in the regulation of methanogenesis in the human large intestine. Gut (1992) 1.24
Contributions of the microbial hydrogen economy to colonic homeostasis. Nat Rev Gastroenterol Hepatol (2012) 1.24
Abnormal breath testing in IBS: a meta-analysis. Dig Dis Sci (2010) 1.20
Relations between transit time, fermentation products, and hydrogen consuming flora in healthy humans. Gut (1996) 1.20
Breath hydrogen response to lactulose in healthy subjects: relationship to methane producing status. Gut (1990) 1.20
Methanogens and anaerobes in a colon segment isolated from the normal fecal stream. Appl Environ Microbiol (1984) 1.14
Bacterial strains from human feces that reduce CO2 to acetic acid. Appl Environ Microbiol (1993) 1.13
Constancy of glucose and starch fermentations by two different human faecal microbial communities. Gut (1989) 1.09
Digestibility and bulking effect of ispaghula husks in healthy humans. Gut (1994) 1.05
Archaea and the human gut: new beginning of an old story. World J Gastroenterol (2014) 1.04
Geographic differences in digoxin inactivation, a metabolic activity of the human anaerobic gut flora. Gut (1989) 1.01
Seventy-five gram glucose tolerance test to assess carbohydrate malabsorption and small bowel bacterial overgrowth. World J Gastroenterol (2006) 1.00
Methanogens, methane and gastrointestinal motility. J Neurogastroenterol Motil (2013) 0.97
Comparative study of hydrogen and methane production in the human colon using caecal and faecal homogenates. Gut (1990) 0.94
Isolation of an antigenically unique methanogen from human feces. Appl Environ Microbiol (1986) 0.93
Increase in colonic methanogens and total anaerobes in aging rats. Appl Environ Microbiol (1989) 0.92
Bowel preparation and the risk of explosion during colonoscopic polypectomy. Gut (1984) 0.91
Association of fecal indicator bacteria with human viruses and microbial source tracking markers at coastal beaches impacted by nonpoint source pollution. Appl Environ Microbiol (2012) 0.91
Methane production and small intestinal bacterial overgrowth in children living in a slum. World J Gastroenterol (2012) 0.89
Reliability and reproducibility of breath hydrogen and methane in male diabetic subjects. Dig Dis Sci (1997) 0.88
Incidence of predominant methanogenic flora in irritable bowel syndrome patients and apparently healthy controls from North India. Dig Dis Sci (2008) 0.88
Fibre, fermentation, flora, and flatus. Gut (1989) 0.86
IBS subjects with methane on lactulose breath test have lower postprandial serotonin levels than subjects with hydrogen. Dig Dis Sci (2004) 0.84
Effect of predominant methanogenic flora on outcome of lactose hydrogen breath test in controls and irritable bowel syndrome patients of north India. Dig Dis Sci (2008) 0.80
Colonic hydrogen elimination and methane production in infants with and without infantile colic syndrome. Dig Dis Sci (2003) 0.80
Is methane a new therapeutic gas? Med Gas Res (2012) 0.79
Methanogenesis in irritable bowel syndrome: a lot of hot air? Dig Dis Sci (2012) 0.77
Children living near a sanitary landfill have increased breath methane and Methanobrevibacter smithii in their intestinal microbiota. Archaea (2014) 0.76
Breath Methane Levels Are Increased Among Patients with Diverticulosis. Dig Dis Sci (2016) 0.76
Modeling of breath methane concentration profiles during exercise on an ergometer. J Breath Res (2016) 0.75
Amounts of viable anaerobes, methanogens, and bacterial fermentation products in feces of rats fed high-fiber or fiber-free diets. Appl Environ Microbiol (1993) 0.75
Dietary pea fiber increases diversity of colonic methanogens of pigs with a shift from Methanobrevibacter to Methanomassiliicoccus-like genus and change in numbers of three hydrogenotrophs. BMC Microbiol (2017) 0.75
Methane excretion in man. Gut (1985) 0.75
Diverticular disease and your mother's diet. Gut (1996) 0.75
Physiological consequences of orthograde lavage bowel preparation for elective colorectal surgery: a review. J R Soc Med (1983) 0.75
Hydrogen and methane gases are frequently detected in the stomach. World J Gastroenterol (2006) 0.75
Hydrogen breath test in schoolchildren. Arch Dis Child (1985) 0.75
Genomics and metagenomics of trimethylamine-utilizing Archaea in the human gut microbiome. ISME J (2017) 0.75
Comparison of inulin and lactulose as reference standards in the breath hydrogen test assessment of carbohydrate malabsorption in patients with chronic pancreatic exocrine insufficiency. Dig Dis Sci (2005) 0.75
Isolation and characterization of Methanobacterium ruminantium n. sp. J Bacteriol (1958) 9.68
INDIGENOUS, NORMAL, AND AUTOCHTHONOUS FLORA OF THE GASTROINTESTINAL TRACT. J Exp Med (1965) 6.72
Persistence of individual strains of Escherichia coli in the intestinal tract of man. J Bacteriol (1950) 5.80
Production and excretion of hydrogen gas in man. N Engl J Med (1969) 4.78
STUDIES ON THE STABILITY OF THE NORMAL HUMAN FECAL FLORA. J Bacteriol (1962) 4.53
Colonization of the mouse intestine with Escherichia coli. J Exp Med (1965) 4.30
Methane fermentation. Annu Rev Microbiol (1967) 3.61
The kinetics of water absorption in the human intestine. Trans Assoc Am Physicians (1961) 3.12
Microbial activity in the bovine rumen: its measurement and relation to bloat. Appl Microbiol (1955) 2.96
Treatment of chronic portal-systemic encephalopathy with lactulose. Lancet (1966) 2.65
Isolation of methanogenic bacteria from feces of man. J Bacteriol (1968) 2.53
The use of expired air to measure intestinal gas formation. Ann N Y Acad Sci (1968) 1.79
Endogenous carbon monoxide production in patients with hemolytic anemia. J Clin Invest (1966) 1.68
A MOLECULAR MECHANISM OF SICKLED ERYTHROCYTE FORMATION. Nature (1964) 1.26
Ecological studies of intestinal bacteria. Relation between the specificity of fecal ABO blood group antigen-degrading enzymes from enteric bacteria and the ABO blood group of the human host. J Clin Invest (1969) 1.26
The quantity and composition of human colonic flatus. Gastroenterology (1949) 1.17
Oxidation of intra-arterially administered carbon 14-labelled methane in sheep. Proc Soc Exp Biol Med (1967) 0.97
Reducing mortality from colorectal cancer by screening for fecal occult blood. Minnesota Colon Cancer Control Study. N Engl J Med (1993) 27.80
Prevention of colorectal cancer by colonoscopic polypectomy. The National Polyp Study Workgroup. N Engl J Med (1993) 21.18
Use of colonoscopy to screen asymptomatic adults for colorectal cancer. Veterans Affairs Cooperative Study Group 380. N Engl J Med (2000) 13.21
The effect of fecal occult-blood screening on the incidence of colorectal cancer. N Engl J Med (2000) 13.19
Colorectal cancer screening: clinical guidelines and rationale. Gastroenterology (1997) 9.70
Colorectal cancer mortality: effectiveness of biennial screening for fecal occult blood. J Natl Cancer Inst (1999) 8.08
A clinical trial of antioxidant vitamins to prevent colorectal adenoma. Polyp Prevention Study Group. N Engl J Med (1994) 5.98
Investigation of small bowel transit time in man utilizing pulmonary hydrogen (H2) measurements. J Lab Clin Med (1975) 5.32
A comparison of symptoms after the consumption of milk or lactose-hydrolyzed milk by people with self-reported severe lactose intolerance. N Engl J Med (1995) 5.02
A comparison of colonoscopy and double-contrast barium enema for surveillance after polypectomy. National Polyp Study Work Group. N Engl J Med (2000) 4.84
Production and excretion of hydrogen gas in man. N Engl J Med (1969) 4.78
Calcium supplements for the prevention of colorectal adenomas. Calcium Polyp Prevention Study Group. N Engl J Med (1999) 4.11
Studies of a flatulent patient. N Engl J Med (1976) 4.05
Induction of heme oxygenase is a rapid, protective response in rhabdomyolysis in the rat. J Clin Invest (1992) 3.50
Lactose maldigestion is not an impediment to the intake of 1500 mg calcium daily as dairy products. Am J Clin Nutr (1998) 2.89
Yogurt--an autodigesting source of lactose. N Engl J Med (1984) 2.84
Use of respiratory hydrogen (H2) excretion to detect carbohydrate malabsorption. J Lab Clin Med (1970) 2.65
Use of pulmonary hydrogen (H 2 ) measurements to quantitate carbohydrate absorption. Study of partially gastrectomized patients. J Clin Invest (1972) 2.50
Risk factors for severe delayed postpolypectomy bleeding. Endoscopy (2008) 2.45
Medical-legal risks of incident cancers after clearing colonoscopy. Am J Gastroenterol (2001) 2.40
Sensitivity, specificity, and positive predictivity of the Hemoccult test in screening for colorectal cancers. The University of Minnesota's Colon Cancer Control Study. Gastroenterology (1989) 2.37
How effective are second-generation antipsychotic drugs? A meta-analysis of placebo-controlled trials. Mol Psychiatry (2008) 2.23
Where does serum amylase come from and where does it go? Gastroenterol Clin North Am (1990) 2.20
Detection of malabsorption of low doses of carbohydrate: accuracy of various breath H2 criteria. Gastroenterology (1993) 2.15
Risk of colorectal cancer in the families of patients with adenomatous polyps. National Polyp Study Workgroup. N Engl J Med (1996) 2.14
The renal clearance of amylase in renal insufficiency, acute pancreatitis, and macroamylasemia. Ann Intern Med (1969) 2.05
Necrotizing enterocolitis. J Pediatr (1975) 2.03
Volume, composition, and source of intestinal gas. Gastroenterology (1970) 1.97
Hydrogen and methane production in man. Ann N Y Acad Sci (1968) 1.90
Fecal hydrogen sulfide production in ulcerative colitis. Am J Gastroenterol (1998) 1.87
The role of intestinal gas in functional abdominal pain. N Engl J Med (1975) 1.85
Quantitative measurement of lactose absorption. Gastroenterology (1976) 1.79
The effect of family interventions on relapse and rehospitalization in schizophrenia--a meta-analysis. Schizophr Bull (2001) 1.72
Incomplete absorption of the carbohydrate in all-purpose wheat flour. N Engl J Med (1981) 1.70
Volume and composition of human intestinal gas determined by means of an intestinal washout technic. N Engl J Med (1971) 1.68
Laparoscopic-assisted resection of colorectal malignancies: a systematic review. Ann Surg (2001) 1.62
Oxidation of hydrogen sulfide and methanethiol to thiosulfate by rat tissues: a specialized function of the colonic mucosa. Biochem Pharmacol (2001) 1.61
Fecal hydrogen production and consumption measurements. Response to daily lactose ingestion by lactose maldigesters. Dig Dis Sci (1997) 1.59
H2 excretion after ingestion of complex carbohydrates. Gastroenterology (1987) 1.57
Factors associated with human immunodeficiency virus seroconversion in homosexual men in three San Francisco cohort studies, 1984-1989. J Acquir Immune Defic Syndr (1993) 1.53
Sensory gating in normals and schizophrenics: a failure to find strong P50 suppression in normals. Biol Psychiatry (1990) 1.52
Combined action of the ACE D- and the G-protein beta3 T-allele in major depression: a possible link to cardiovascular disease? Mol Psychiatry (2002) 1.49
Small flat adenomas appear to have little clinical importance in Western countries. Gastrointest Endosc (1995) 1.47
The National Polyp Study. Design, methods, and characteristics of patients with newly diagnosed polyps. The National Polyp Study Workgroup. Cancer (1992) 1.46
Reproducibility of measurements of trace gas concentrations in expired air. Gastroenterology (1991) 1.39
Sensitivity of HPLC and conventional bilirubin measurements in the detection of early cholestasis. J Lab Clin Med (1995) 1.38
Colonic conservation of malabsorbed carbohydrate. Gastroenterology (1980) 1.35
Necrotizing enterocolitis. An emerging entity in the regional infant intensive care facility. Arch Surg (1974) 1.34
Use of breath hydrogen (H2) to quantitate small bowel transit time following partial gastrectomy. J Lab Clin Med (1977) 1.34
Methanogens outcompete sulphate reducing bacteria for H2 in the human colon. Gut (1994) 1.32
Fate of soluble carbohydrate in the colon of rats and man. J Clin Invest (1976) 1.31
Factors affecting hydrogen production and consumption by human fecal flora. The critical roles of hydrogen tension and methanogenesis. J Clin Invest (1992) 1.30
Pancreatic endocrine function in cystic fibrosis. J Pediatr (1991) 1.28
Definitions of response and remission in schizophrenia: recommendations for their use and their presentation. Acta Psychiatr Scand Suppl (2009) 1.27
Competition for hydrogen by human faecal bacteria: evidence for the predominance of methane producing bacteria. Gut (1991) 1.24
Hydrogen (H2) catabolism in the colon of the rat. J Lab Clin Med (1974) 1.22
Floating stools--flatus versus fat. N Engl J Med (1972) 1.20
Severe adverse drug reactions of antidepressants: results of the German multicenter drug surveillance program AMSP. Pharmacopsychiatry (2004) 1.16
Tolerance to the daily ingestion of two cups of milk by individuals claiming lactose intolerance. Am J Clin Nutr (1997) 1.14
Use of breath hydrogen (H2) in the study of carbohydrate absorption. Am J Dig Dis (1977) 1.14
Physical and mental status at 4 years of age of survivors of the respiratory distress syndrome. Follow-up report from the collaborative study. J Pediatr (1975) 1.13
Gastrointestinal transit in thyroid disease. Gastroenterology (1984) 1.13
The T102C polymorphism of the 5-HT2A-receptor gene in fibromyalgia. Neurobiol Dis (1999) 1.12
Rectal washout eliminates exfoliated malignant cells. Dis Colon Rectum (1998) 1.12
Lactose malabsorption from yogurt, pasteurized yogurt, sweet acidophilus milk, and cultured milk in lactase-deficient individuals. Am J Clin Nutr (1984) 1.11
Low thyroid hormones and respiratory-distress syndrome of the newborn. Studies on cord blood. N Engl J Med (1976) 1.11
Gaseousness and intestinal gas. Med Clin North Am (1978) 1.10
Multiple antibiotic resistance in clinical strains of Neisseria gonorrhoeae isolated in South Carolina. Antimicrob Agents Chemother (1976) 1.09
Re: "Arsenic ingestion and internal cancers: a review". Am J Epidemiol (1993) 1.09
Host heme catabolism in drug-sensitive and drug-resistant malaria. J Lab Clin Med (1977) 1.08
A rapid and simple assay to determine if macroamylase is the cause of hyperamylasemia. Gastroenterology (1982) 1.06
Hyperamylasemia from the binding of serum amylase by an 11S IgA globulin. N Engl J Med (1968) 1.06
Hepatitis B immune globulin for accidental exposures among medical personnel: final report of a multicenter controlled trial. J Infect Dis (1978) 1.05
Use of inert gases to study the interaction of blood flow and diffusion during passive absorption from the gastrointestinal tract of the rat. J Clin Invest (1973) 1.04
Serum tests for pancreatitis in patients with abdominal pain. Arch Pathol Lab Med (1985) 1.03
Prevention of colorectal cancer: guidelines based on new data. WHO Collaborating Center for the Prevention of Colorectal Cancer. Bull World Health Organ (1995) 1.03
Carbon monoxide production from heme compounds by bacteria. J Bacteriol (1972) 1.03
Decreased insulin binding in cultured lymphocytes from two patients with extreme insulin resistance. J Clin Endocrinol Metab (1982) 1.03
Isoelectric focusing studies of human serum and tissue isoamylases. J Lab Clin Med (1977) 1.02
Nicotine: cotinine levels in blood during cessation of smoking. Compr Psychiatry (1977) 1.00
The AMSP drug safety program: methods and global results. Pharmacopsychiatry (2004) 0.98
Pancreatic supplements reduce symptomatic response of healthy subjects to a high fat meal. Dig Dis Sci (1999) 0.98
Gaseous response to ingestion of a poorly absorbed fructo-oligosaccharide sweetener. Am J Clin Nutr (1987) 0.98
Diagnostic value of routine isoamylase assay of hyperamylasemic serum. Gastroenterology (1982) 0.98
Paracellular intestinal transport of six-carbon sugars is negligible in the rat. Gastroenterology (1995) 0.98
Tin protoporphyrin inhibits carbon monoxide production in adult mice. Pediatr Res (1985) 0.98