Published in Biochem J on October 01, 1979
Inhibition of protohaem ferro-lyase by N-substituted porphyrins. Structural requirements for the inhibitory effect. Biochem J (1980) 1.46
Autocatalytic alkylation of the cytochrome P-450 prosthetic haem group by 1-aminobenzotriazole. Isolation of an NN-bridged benzyne-protoporphyrin IX adduct. Biochem J (1981) 1.24
Drug-induced conversion of liver haem into modified porphyrins. Evidence for two classes of products. Biochem J (1980) 1.06
Inhibition of protohaem ferro-lyase in experimental porphyria. Isolation and partial characterization of a modified porphyrin inhibitor. Biochem J (1980) 1.02
Quantitative analysis of flux along the gluconeogenic, glycolytic and pentose phosphate pathways under reducing conditions in hepatocytes isolated from fed rats. Biochem J (1983) 0.94
Metabolism of hepatic haem and 'green pigments' in rats given 2-allyl-2-isopropylacetamide and ferric citrate. A new model for hepatic haem turnover. Biochem J (1980) 0.91
Isolation of two N-monosubstituted protoporphyrins, bearing either the whole drug or a methyl group on the pyrrole nitrogen atom, from liver of mice given griseofulvin. Biochem J (1991) 0.90
Phenylhydrazine-mediated induction of haem oxygenase activity in rat liver and kidney and development of hyperbilirubinaemia. Inhibition by zinc-protoporphyrin. Biochem J (1984) 0.85
Destruction of liver haem by norethindrone. Conversion into green pigments. Biochem J (1981) 0.84
Formation of N-alkylated protoporphyrin IX in the livers of mice after diethylnitrosamine treatment. Biochem J (1983) 0.82
Loss of haem in rat liver caused by the porphyrogenic agent 2-allyl-2-isopropylacetamide. Biochem J (1971) 2.39
Suicidal inactivation of cytochrome P-450. Formation of a heme-substrate covalent adduct. Biochem Biophys Res Commun (1978) 1.43
Rapid loss of cytochrome P-450 and haem caused in the liver microsomes by the porphyrogenic agent 2-allyl-2-isopropylacetamide. FEBS Lett (1970) 1.43
Increased liver haem degradation caused by foreign chemicals: a comparison of the effects of 2-allyl-2-isopropylacetamide and cobaltous chloride. Biochem Soc Trans (1976) 1.36
Drug-induced destruction of cytochrome P-450. Drug Metab Dispos (1974) 1.22
Degradation of hepatic haem to porphyrins and oxophlorins in rats treated with 2-allyl-2-isopropylacetamide. Biochem Soc Trans (1976) 1.14
Loss of haem from cytochrome P-450 caused by lipid peroxidation and 2-allyl-2-isoprophylacetamide. An abnormal pathway not involving production of carbon monoxide. Biochem J (1977) 1.07
N-methylporphyrins. Ann N Y Acad Sci (1973) 1.03
Breakdown of cytochrome P-450 heme by secobarbital and other allyl-containing barbiturates. Drug Metab Dispos (1974) 1.00
Alkylation of coenzymes and the acute effects of alkylating hepatotoxins. FEBS Lett (1976) 0.92
Formylation of iron (3) porphyrins and chlorins of natural origin. J Chem Soc Perkin 1 (1970) 0.85
Porphyrins with formyl groups. III. Preparation of chlorocruoroporphyrin and diformyldeuteroporphyrin. Aust J Exp Biol Med Sci (1952) 0.84
Defective inflammatory response in interleukin 6-deficient mice. J Exp Med (1994) 2.92
Loss of haem in rat liver caused by the porphyrogenic agent 2-allyl-2-isopropylacetamide. Biochem J (1971) 2.39
Studies on the mechanism of experimental porphyria produced by 3,5-diethoxycarbonyl-1,4-dihydrocollidine. Role of a porphyrin-like inhibitor of protohaem ferro-lyase. Biochem J (1979) 1.46
Inhibition of protohaem ferro-lyase by N-substituted porphyrins. Structural requirements for the inhibitory effect. Biochem J (1980) 1.46
Increased liver haem degradation caused by foreign chemicals: a comparison of the effects of 2-allyl-2-isopropylacetamide and cobaltous chloride. Biochem Soc Trans (1976) 1.36
Decreased liver activity of porphyrin-metal chelatase in hepatic porphyria caused by 3,5-diethoxycarbonyl-1,4-dihydrocollidine. Studies in rats and mice. Biochem J (1973) 1.34
Cytokine induction of haem oxygenase mRNA in mouse liver. Interleukin 1 transcriptionally activates the haem oxygenase gene. Biochem J (1993) 1.33
Biochemical changes in rat liver after administration of carbon disulphide, with particular reference to microsomal changes. Biochem Pharmacol (1969) 1.32
Effects of carbon disulphide on the liver of rats. Br J Ind Med (1969) 1.28
Drug-induced destruction of cytochrome P-450. Drug Metab Dispos (1974) 1.22
Iron-dependent loss of liver cytochrome P-450 haem in vivo and in vitro. FEBS Lett (1973) 1.18
The effect of drugs on 5-aminolaevulinate synthetase and other enzymes in the pathway of liver haem biosynthesis. Basic Life Sci (1975) 1.18
Decreased levels of cytochrome P-450 and catalase in hepatic porphyria caused by substituted acetamides and barbiturates. Importance of the allyl group in the molecule of the active drugs. Chem Biol Interact (1972) 1.18
The effect of pressure and guanidine hydrochloride on azurins mutated in the hydrophobic core. Eur J Biochem (1999) 1.09
Loss of haem from cytochrome P-450 caused by lipid peroxidation and 2-allyl-2-isoprophylacetamide. An abnormal pathway not involving production of carbon monoxide. Biochem J (1977) 1.07
Drug-induced conversion of liver haem into modified porphyrins. Evidence for two classes of products. Biochem J (1980) 1.06
Growth charts, growth velocity and bone development in childhood obesity. Int J Obes Relat Metab Disord (1995) 1.06
Drug interactions in experimental hepatic porphyria. A model for the exacerbation by drugs of human variegate porphyria. Enzyme (1973) 1.05
Mechanisms of endotoxin-induced haem oxygenase mRNA accumulation in mouse liver: synergism by glutathione depletion and protection by N-acetylcysteine. Biochem J (1994) 1.04
Structural isomerism and chirality of N-monosubstituted protoporphyrins. FEBS Lett (1982) 1.03
Flexibility of helix 2 in the human glutathione transferase P1-1. time-resolved fluorescence spectroscopy. J Biol Chem (1998) 1.02
Inhibition of protohaem ferro-lyase in experimental porphyria. Isolation and partial characterization of a modified porphyrin inhibitor. Biochem J (1980) 1.02
In vitro inhibitory effect on porphyrinogen carboxylyase of liver extracts from TCDD treated mice. Toxicol Lett (1984) 1.00
Inhibition of haem synthesis caused by cobalt in rat liver. Evidence for two different sites of action. Biochem J (1977) 1.00
Liver production of N-alkylated porphyrins caused in mice by treatment with substituted dihydropyridines. Evidence that the alkyl group on the pyrrole nitrogen atom originates from the drug. FEBS Lett (1981) 0.99
Drug-induced accumulation of uroporphyrin in chicken hepatocyte cultures. Structural requirements for the effect and role of exogenous iron. Biochem J (1984) 0.98
Opposite effects of Ca(2+) and GTP binding on tissue transglutaminase tertiary structure. J Biol Chem (2000) 0.97
Drugs and the hepatic porphyrias. Clin Haematol (1980) 0.97
Effects of phlebotomy on urinary porphyrin pattern and liver histology in patients with porphyria cutanea tarda. Am J Med Sci (1983) 0.97
Stimulation of liver cholesterol synthesis by actinomycin D. Biochem J (1968) 0.94
Effect of 3,5-diethoxycarbonyl-1,4-dihydrocollidine on degradation of liver haem. Enzyme (1973) 0.93
Mitochondrial dysfunction and death in motor neurons exposed to the glutathione-depleting agent ethacrynic acid. J Neurol Sci (2003) 0.93
A comparative study of tamoxifen metabolism in female rat, mouse and human liver microsomes. Carcinogenesis (1994) 0.92
Kupffer cell depletion partially prevents hepatic heme oxygenase 1 messenger RNA accumulation in systemic inflammation in mice: role of interleukin 1beta. Hepatology (1998) 0.92
A difference between two strains of rats in their liver non-haem iron content and in their response to the porphyrogenic effect of hexachlorobenzene. Chem Biol Interact (1979) 0.91
Genotoxicity of tamoxifen, tamoxifen epoxide and toremifene in human lymphoblastoid cells containing human cytochrome P450s. Carcinogenesis (1994) 0.91
The effect of cobaltous chloride on liver haem metabolism in the rat. Evidence for inhibition of haem synthesis and for increased haem degradation. Ann Clin Res (1976) 0.91
Isolation of two N-monosubstituted protoporphyrins, bearing either the whole drug or a methyl group on the pyrrole nitrogen atom, from liver of mice given griseofulvin. Biochem J (1991) 0.90
Experimental porphyrias as models for human hepatic porphyrias. Semin Hematol (1977) 0.90
NADPH: cytochrome P-450 reductase in olfactory epithelium. Relevance to cytochrome P-450-dependent reactions. Biochem J (1986) 0.90
Altered urinary porphyrin excretion in a human population chronically exposed to arsenic in Mexico. Hum Exp Toxicol (1994) 0.90
Formation of cobalt protoporphyrin by chicken hepatocytes in culture. Relationship to decrease of 5-aminolaevulinate synthase caused by cobalt. Biochem Pharmacol (1982) 0.87
DNA damage as assessed by 32P-postlabelling in three rat strains exposed to dietary tamoxifen: the relationship between cell proliferation and liver tumour formation. Carcinogenesis (1995) 0.86
Studies on the inhibition of ferrochelatase by N-alkylated dicarboxylic porphyrins. Steric factors involved and evidence that the inhibition is reversible. Biochem J (1985) 0.86
Hemozoin stability and dormant induction of heme oxygenase in hemozoin-fed human monocytes. Mol Biochem Parasitol (1999) 0.86
Microsomal styrene mono-oxygenase and styrene epoxide hydrase activities in rats. Xenobiotica (1976) 0.86
Beta-lactam antibiotics active against methicillin-resistant Staphylococcus aureus. J Infect Dis (1991) 0.85
The effect of N-methylprotoporphyrin and succinyl-acetone on the regulation of heme biosynthesis in chicken hepatocytes in culture. FEBS Lett (1983) 0.85
Hydroxychloroquine versus phlebotomy in the treatment of porphyria cutanea tarda. Br J Dermatol (1983) 0.85
Brain 5-aminolaevulinate synthase. Developmental aspects and evidence for regulatory role. Biochem J (1981) 0.84
Plasma and red blood cell phospholipids in chronic liver diseases. Clin Chim Acta (1975) 0.84
Strain and sex differences in the response of mice to drugs that induce protoporphyria: role of porphyrin biosynthesis and removal. J Biochem Toxicol (1990) 0.84
Studies on the mechanism of experimental porphyria and ferrochelatase inhibition produced by 3,5-diethoxycarbonyl-1,4-dihydrocollidine. Int J Biochem (1980) 0.83
Loss of haem and haemoproteins during the generation of superoxide anion and hydrogen peroxide: a pathway not involving production of carbon monoxide. Int J Biochem (1981) 0.83
Drugs and porphyria. S Afr Med J (1971) 0.82
Ciliary neurotrophic factor (CNTF) induces serum amyloid A, hypoglycaemia and anorexia, and potentiates IL-1 induced corticosterone and IL-6 production in mice. Cytokine (1995) 0.82
Role of acute-phase proteins in interleukin-1-induced nonspecific resistance to bacterial infections in mice. Antimicrob Agents Chemother (1993) 0.81
Oxidative injury mediated by the hepatic cytochrome P-450 system in conjunction with cellular iron. Effects on the pathway of haem biosynthesis. Xenobiotica (1990) 0.81
Porphyrogenic effect of chronic treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin in female rats. Dose--effect relationship following urinary excretion of porphyrins. Toxicol Appl Pharmacol (1981) 0.81
Formation of N-methyl protoporphyrin in chemically-induced protoporphyria. Studies with a novel porphyrogenic agent. Arch Toxicol (1993) 0.81
Time-dependent porphyric response in mice subchronically exposed to arsenic. Hum Exp Toxicol (1995) 0.81
Olfactory cytochrome P-450. Studies with suicide substrates of the haemoprotein. Biochem J (1988) 0.80
Tamoxifen induces short-term cumulative DNA damage and liver tumors in rats: promotion by phenobarbital. Cancer Res (1995) 0.80
N-alkylation of exogenous haem analogues caused by drugs in isolated hepatocytes. Structural isomerism and chirality of the resulting porphyrins. Biochem J (1986) 0.80
Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on drug metabolism and hepatic microsomes of rats and mice. Environ Health Perspect (1973) 0.80
Modulation of cerebellar and hepatic nitric oxide synthase by exogenous arginine and endotoxin. Nitric Oxide (2001) 0.80
Inhibitors of cytochrome P450 suppress tumor necrosis factor production. Cell Immunol (1993) 0.79
The mechanism of the suicidal, reductive inactivation of microsomal cytochrome P-450 by carbon tetrachloride. Biochem Pharmacol (1988) 0.79
Neoantigen formation and clastogenic action of HCFC-123 and perchloroethylene in human MCL-5 cells. Toxicol Lett (2001) 0.79
Porphyrinogenic effect of hexachlorobenzene and 2,3,7,8-tetrachlorodibenzo-para-dioxin: is an inhibitor involved in uroporphyrinogen decarboxylase inactivation? IARC Sci Publ (1986) 0.79
Studied on cerebellar haem metabolism in the rat in vivo. J Neurochem (1982) 0.79
Protoporphyria induced by the orally active iron chelator 1,2-diethyl-3-hydroxypyridin-4-one in C57BL/10ScSn mice. Blood (1997) 0.79
Induction of CYP2B1 and 3A1, and associated monoxygenase activities by tamoxifen and certain analogues in the livers of female rats and mice. Biochem Pharmacol (1993) 0.78
Oxidative metabolism of carbon disulphide by the rat. Effect of treatments which modify the liver toxicity of carbon disulphide. Chem Biol Interact (1973) 0.78
The glutathione-linked metabolism of 2-allyl-2-isopropy-lacetamide in rats. Further evidence for the formation of a reactive metabolite. Chem Biol Interact (1978) 0.78
Bile secretion and liver microsomal mixed function oxidase system in mice with griseofulvin-induced hepatic protoporphyria. Toxicology (1983) 0.78
The effect of cobalt on the uptake of plasma iron by the liver. Biochem J (1976) 0.78
Intercalation with DNA is a prerequisite for daunomycin, adriamycin and its congeners in inhibiting DNAase I. Chem Biol Interact (1978) 0.78
[Rehabilitation of deafness in the elderly: multidisciplinary intervention in experimental university center]. Acta Otorhinolaryngol Ital (1996) 0.78
A comparative trial of desferrioxamine and hydroxychloroquine for treatment of porphyria cutanea tarda in alcoholic patients. Photodermatol (1984) 0.78
Role of cytochrome P450 1A2 in bilirubin degradation Studies in Cyp1a2 (-/-) mutant mice. Biochem Pharmacol (2001) 0.78
Resolution of the heterogeneous fluorescence in multi-tryptophan proteins: ascorbate oxidase. Eur J Biochem (1998) 0.78
Isolation and structure determination of enzymatically formed styrene oxide glutathione conjugates. Chem Biol Interact (1979) 0.77
Cytomegalovirus primo-infection in a patient with idiopathic proctitis. Am J Gastroenterol (1986) 0.77
The determination of uroporphyrinogen decarboxylase in tissues by high-performance liquid chromatography coupled to fluorescence detection. J Chromatogr (1982) 0.77
Depression of liver metabolism and induction of cytokine release by diphtheria and tetanus toxoids and pertussis vaccines: role of Bordetella pertussis cells in toxicity. Infect Immun (1994) 0.77
Decarboxylation of uroporphyrinogen I and III in 2,3,7,8-tetrachlorodibenzo-p-dioxin induced porphyria in mice. Int J Biochem (1984) 0.77
Substrate-dependent irreversible inactivation of cytochrome P-450: conversion of its haem moiety into modified porphyrins. Ciba Found Symp (1980) 0.77
Effects of iron overload on bile secretion and hepatic porphyrin metabolism in ethinyl estradiol-treated rats. Toxicology (1986) 0.77
Modulation of constitutive and inducible hepatic cytochrome(s) P-450 by interferon beta in mice. J Hepatol (1996) 0.77
Mechanisms of interleukin-2-induced hydrothoraxy in mice: protective effect of endotoxin tolerance and dexamethasone and possible role of reactive oxygen intermediates. J Immunother Emphasis Tumor Immunol (1994) 0.77
N-Dealkylation of chlorimipramine and chlorpromazine by rat liver microsomal cytochrome P450 isoenzymes. J Pharm Pharmacol (1998) 0.77
Investigations on the role of free radical processes in hexachlorobenzene-induced porphyria in mice. J Biochem Toxicol (1988) 0.77
Drug-induced uroporphyria in chicken hepatocyte cultures. IARC Sci Publ (1986) 0.77
[Total and fractionized plasma phospholipids in chronic liver diseases]. Minerva Med (1975) 0.76