Published in Biochem J on January 15, 1977
Reversal of alpha,alpha'-Dipyridyl-induced Porphyrin Synthesis in Etiolated and Greening Red Kidney Bean Leaves. Plant Physiol (1979) 1.32
Formation of cobalt protoporphyrin in the liver of rats. A mechanism for the inhibition of liver haem biosynthesis by inorganic cobalt. Biochem J (1979) 1.19
Conversion of 5-aminolaevulinate into haem by liver homogenates. Comparison of rat and chick embryo. Biochem J (1981) 1.06
Hepatic heme metabolism and its control. Yale J Biol Med (1979) 1.02
Decrease in hepatic cytochrome P-450 by cobalt. Evidence for a role of cobalt protoporphyrin. Biochem J (1982) 0.99
Brain 5-aminolaevulinate synthase. Developmental aspects and evidence for regulatory role. Biochem J (1981) 0.84
Exposure to cobalt causes transcriptomic and proteomic changes in two rat liver derived cell lines. PLoS One (2013) 0.81
Formation of cytochrome P-450 containing haem or cobalt-protoporphyrin in liver homogenates of rats treated with phenobarbital and allylisopropylacetamide. Biochem J (1984) 0.80
Inhibitory effect of zinc on stimulated erythropoietin synthesis in HepG2 cells. Biochem J (1992) 0.76
Increase in activity of alpha-aminolevulinic acid synthetase in liver mitochondria induced by feeding of 3,5-dicarbethoxy-1,4-dihydrocollidine. J Biol Chem (1963) 4.35
A new method of hemin isolation. Biochim Biophys Acta (1957) 4.04
Loss of haem in rat liver caused by the porphyrogenic agent 2-allyl-2-isopropylacetamide. Biochem J (1971) 2.39
The role of adenosine triphosphate deficiency in ethionine-induced inhibition of protein synthesis. J Biol Chem (1963) 1.89
The effect of cobalt chloride administration on the synthesis of hepatic microsomal cytochrome P-450. Biochem Biophys Res Commun (1971) 1.41
Increased liver haem degradation caused by foreign chemicals: a comparison of the effects of 2-allyl-2-isopropylacetamide and cobaltous chloride. Biochem Soc Trans (1976) 1.36
Effect of cobalt on synthesis of heme and cytochrome P-450 in the liver. Studies of adult rat hepatocytes in primary monolayer culture and in vivo. J Biol Chem (1976) 1.24
The effect of drugs on 5-aminolaevulinate synthetase and other enzymes in the pathway of liver haem biosynthesis. Basic Life Sci (1975) 1.18
Cobalt inhibition of synthesis and induction of delta-aminolevulinate synthase in liver. Proc Natl Acad Sci U S A (1976) 1.18
Decreased levels of cytochrome P-450 and catalase in hepatic porphyria caused by substituted acetamides and barbiturates. Importance of the allyl group in the molecule of the active drugs. Chem Biol Interact (1972) 1.18
The biological action of cobalt and other metals. II. The mechanism of the respiratory inhibition produced by cobalt in mammalian tissues. Biochim Biophys Acta (1962) 1.06
The regulation of heme synthesis related to drug metabolism. Drug Metab Dispos (1974) 1.02
Soluble -aminolevulinic acid synthetase of rat liver. II. Studies related to the mechanism of enzyme action and hemin inhibition. J Biol Chem (1972) 0.98
Effect of cobalt on the synthesis and degradation of hepatic catalase in vivo. Biochem J (1974) 0.96
Effect of cobalt on heme biosynthesis in rat liver and spleen. J Biochem (1975) 0.89
Loss of haem in rat liver caused by the porphyrogenic agent 2-allyl-2-isopropylacetamide. Biochem J (1971) 2.39
Studies on the mechanism of experimental porphyria produced by 3,5-diethoxycarbonyl-1,4-dihydrocollidine. Role of a porphyrin-like inhibitor of protohaem ferro-lyase. Biochem J (1979) 1.46
Inhibition of protohaem ferro-lyase by N-substituted porphyrins. Structural requirements for the inhibitory effect. Biochem J (1980) 1.46
Increased liver haem degradation caused by foreign chemicals: a comparison of the effects of 2-allyl-2-isopropylacetamide and cobaltous chloride. Biochem Soc Trans (1976) 1.36
Decreased liver activity of porphyrin-metal chelatase in hepatic porphyria caused by 3,5-diethoxycarbonyl-1,4-dihydrocollidine. Studies in rats and mice. Biochem J (1973) 1.34
Biochemical changes in rat liver after administration of carbon disulphide, with particular reference to microsomal changes. Biochem Pharmacol (1969) 1.32
Effects of carbon disulphide on the liver of rats. Br J Ind Med (1969) 1.28
Alteration of the porphyrin nucleus of cytochrome P-450 caused in the liver by treatment with allyl-containing drugs. Is the modified porphyrin N-substituted? Biochem J (1979) 1.24
Drug-induced destruction of cytochrome P-450. Drug Metab Dispos (1974) 1.22
Formation of cobalt protoporphyrin in the liver of rats. A mechanism for the inhibition of liver haem biosynthesis by inorganic cobalt. Biochem J (1979) 1.19
Iron-dependent loss of liver cytochrome P-450 haem in vivo and in vitro. FEBS Lett (1973) 1.18
The effect of drugs on 5-aminolaevulinate synthetase and other enzymes in the pathway of liver haem biosynthesis. Basic Life Sci (1975) 1.18
Decreased levels of cytochrome P-450 and catalase in hepatic porphyria caused by substituted acetamides and barbiturates. Importance of the allyl group in the molecule of the active drugs. Chem Biol Interact (1972) 1.18
The effect of pressure and guanidine hydrochloride on azurins mutated in the hydrophobic core. Eur J Biochem (1999) 1.09
Conversion of liver haem into N-substituted porphyrins or green pigments. Nature of the substituent at the pyrrole nitrogen atom. FEBS Lett (1980) 1.08
Loss of haem from cytochrome P-450 caused by lipid peroxidation and 2-allyl-2-isoprophylacetamide. An abnormal pathway not involving production of carbon monoxide. Biochem J (1977) 1.07
Drug-induced conversion of liver haem into modified porphyrins. Evidence for two classes of products. Biochem J (1980) 1.06
Growth charts, growth velocity and bone development in childhood obesity. Int J Obes Relat Metab Disord (1995) 1.06
Drug interactions in experimental hepatic porphyria. A model for the exacerbation by drugs of human variegate porphyria. Enzyme (1973) 1.05
Structural isomerism and chirality of N-monosubstituted protoporphyrins. FEBS Lett (1982) 1.03
Flexibility of helix 2 in the human glutathione transferase P1-1. time-resolved fluorescence spectroscopy. J Biol Chem (1998) 1.02
Inhibition of protohaem ferro-lyase in experimental porphyria. Isolation and partial characterization of a modified porphyrin inhibitor. Biochem J (1980) 1.02
Liver production of N-alkylated porphyrins caused in mice by treatment with substituted dihydropyridines. Evidence that the alkyl group on the pyrrole nitrogen atom originates from the drug. FEBS Lett (1981) 0.99
Drug-induced accumulation of uroporphyrin in chicken hepatocyte cultures. Structural requirements for the effect and role of exogenous iron. Biochem J (1984) 0.98
Opposite effects of Ca(2+) and GTP binding on tissue transglutaminase tertiary structure. J Biol Chem (2000) 0.97
Drugs and the hepatic porphyrias. Clin Haematol (1980) 0.97
Stimulation of liver cholesterol synthesis by actinomycin D. Biochem J (1968) 0.94
Effect of 3,5-diethoxycarbonyl-1,4-dihydrocollidine on degradation of liver haem. Enzyme (1973) 0.93
A comparative study of tamoxifen metabolism in female rat, mouse and human liver microsomes. Carcinogenesis (1994) 0.92
A difference between two strains of rats in their liver non-haem iron content and in their response to the porphyrogenic effect of hexachlorobenzene. Chem Biol Interact (1979) 0.91
Genotoxicity of tamoxifen, tamoxifen epoxide and toremifene in human lymphoblastoid cells containing human cytochrome P450s. Carcinogenesis (1994) 0.91
The effect of cobaltous chloride on liver haem metabolism in the rat. Evidence for inhibition of haem synthesis and for increased haem degradation. Ann Clin Res (1976) 0.91
Isolation of two N-monosubstituted protoporphyrins, bearing either the whole drug or a methyl group on the pyrrole nitrogen atom, from liver of mice given griseofulvin. Biochem J (1991) 0.90
Experimental porphyrias as models for human hepatic porphyrias. Semin Hematol (1977) 0.90
NADPH: cytochrome P-450 reductase in olfactory epithelium. Relevance to cytochrome P-450-dependent reactions. Biochem J (1986) 0.90
Altered urinary porphyrin excretion in a human population chronically exposed to arsenic in Mexico. Hum Exp Toxicol (1994) 0.90
Formation of cobalt protoporphyrin by chicken hepatocytes in culture. Relationship to decrease of 5-aminolaevulinate synthase caused by cobalt. Biochem Pharmacol (1982) 0.87
Studies on the inhibition of ferrochelatase by N-alkylated dicarboxylic porphyrins. Steric factors involved and evidence that the inhibition is reversible. Biochem J (1985) 0.86
Hemozoin stability and dormant induction of heme oxygenase in hemozoin-fed human monocytes. Mol Biochem Parasitol (1999) 0.86
DNA damage as assessed by 32P-postlabelling in three rat strains exposed to dietary tamoxifen: the relationship between cell proliferation and liver tumour formation. Carcinogenesis (1995) 0.86
The effect of N-methylprotoporphyrin and succinyl-acetone on the regulation of heme biosynthesis in chicken hepatocytes in culture. FEBS Lett (1983) 0.85
Brain 5-aminolaevulinate synthase. Developmental aspects and evidence for regulatory role. Biochem J (1981) 0.84
Strain and sex differences in the response of mice to drugs that induce protoporphyria: role of porphyrin biosynthesis and removal. J Biochem Toxicol (1990) 0.84
Loss of haem and haemoproteins during the generation of superoxide anion and hydrogen peroxide: a pathway not involving production of carbon monoxide. Int J Biochem (1981) 0.83
Studies on the mechanism of experimental porphyria and ferrochelatase inhibition produced by 3,5-diethoxycarbonyl-1,4-dihydrocollidine. Int J Biochem (1980) 0.83
Drugs and porphyria. S Afr Med J (1971) 0.82
Labelling in vivo and chirality of griseofulvin-derived N-alkylated protoporphyrins. Biochem J (1991) 0.82
Oxidative injury mediated by the hepatic cytochrome P-450 system in conjunction with cellular iron. Effects on the pathway of haem biosynthesis. Xenobiotica (1990) 0.81
Time-dependent porphyric response in mice subchronically exposed to arsenic. Hum Exp Toxicol (1995) 0.81
Formation of N-methyl protoporphyrin in chemically-induced protoporphyria. Studies with a novel porphyrogenic agent. Arch Toxicol (1993) 0.81
Determination of the structure of an N-substituted protoporphyrin isolated from the livers of griseofulvin-fed mice. Biochem J (1995) 0.80
Tamoxifen induces short-term cumulative DNA damage and liver tumors in rats: promotion by phenobarbital. Cancer Res (1995) 0.80
Modulation of cerebellar and hepatic nitric oxide synthase by exogenous arginine and endotoxin. Nitric Oxide (2001) 0.80
Olfactory cytochrome P-450. Studies with suicide substrates of the haemoprotein. Biochem J (1988) 0.80
Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on drug metabolism and hepatic microsomes of rats and mice. Environ Health Perspect (1973) 0.80
N-alkylation of exogenous haem analogues caused by drugs in isolated hepatocytes. Structural isomerism and chirality of the resulting porphyrins. Biochem J (1986) 0.80
Two pathways of iron-catalyzed oxidation of bilirubin: effect of desferrioxamine and trolox, and comparison with microsomal oxidation. Free Radic Biol Med (1993) 0.79
Protoporphyria induced by the orally active iron chelator 1,2-diethyl-3-hydroxypyridin-4-one in C57BL/10ScSn mice. Blood (1997) 0.79
Neoantigen formation and clastogenic action of HCFC-123 and perchloroethylene in human MCL-5 cells. Toxicol Lett (2001) 0.79
Effect of tamoxifen feeding on metabolic activation of tamoxifen by the liver of the rhesus monkey: does liver accumulation of inhibitory metabolites protect from tamoxifen-dependent genotoxicity and cancer? Carcinogenesis (1996) 0.79
The mechanism of the suicidal, reductive inactivation of microsomal cytochrome P-450 by carbon tetrachloride. Biochem Pharmacol (1988) 0.79
Studied on cerebellar haem metabolism in the rat in vivo. J Neurochem (1982) 0.79
Inducible bilirubin-degrading system in the microsomal fraction of rat liver. Mol Pharmacol (1989) 0.79
Accelerated conversion of heme to bile pigments caused in the liver by carbon disulfide and other sulfur-containing chemicals. Mol Pharmacol (1978) 0.79
Oxidative metabolism of carbon disulphide by the rat. Effect of treatments which modify the liver toxicity of carbon disulphide. Chem Biol Interact (1973) 0.78
Occurrence and biological properties of N-methyl protoporphyrin. Ann N Y Acad Sci (1987) 0.78
Induction of CYP2B1 and 3A1, and associated monoxygenase activities by tamoxifen and certain analogues in the livers of female rats and mice. Biochem Pharmacol (1993) 0.78
The glutathione-linked metabolism of 2-allyl-2-isopropy-lacetamide in rats. Further evidence for the formation of a reactive metabolite. Chem Biol Interact (1978) 0.78
Resolution of the heterogeneous fluorescence in multi-tryptophan proteins: ascorbate oxidase. Eur J Biochem (1998) 0.78
The effect of cobalt on the uptake of plasma iron by the liver. Biochem J (1976) 0.78
Role of cytochrome P450 1A2 in bilirubin degradation Studies in Cyp1a2 (-/-) mutant mice. Biochem Pharmacol (2001) 0.78
Substrate-dependent irreversible inactivation of cytochrome P-450: conversion of its haem moiety into modified porphyrins. Ciba Found Symp (1980) 0.77
Drug-induced uroporphyria in chicken hepatocyte cultures. IARC Sci Publ (1986) 0.77
N-Dealkylation of chlorimipramine and chlorpromazine by rat liver microsomal cytochrome P450 isoenzymes. J Pharm Pharmacol (1998) 0.77
Liver cholesterol metabolism following trauma. Evidence for increased rate of cholesterol synthesis and breakdown. Biochim Biophys Acta (1969) 0.76
The effects of drugs on the activities of 5-aminolaevulinate synthetase and other enzymes in the pathway of haem biosynthesis. Biochem J (1972) 0.76