Published in Circ Res on March 01, 1970
Adenosine receptors and the heart: role in regulation of coronary blood flow and cardiac electrophysiology. Handb Exp Pharmacol (2009) 1.56
The release of adenosine and inosine from canine subcutaneous adipose tissue by nerve stimulation and noradrenaline. J Physiol (1981) 1.39
Release of adenosine from human hearts during angina induced by rapid atrial pacing. J Clin Invest (1974) 1.16
Role of S-adenosylhomocysteine hydrolase in adenosine metabolism in mammalian heart. Biochem J (1981) 1.14
Systematic variations in the content of the purine nucleotides in the steady-state perfused rat heart. Evidence for the existence of controlled storage and release of adenine nucleotides. Biochem J (1978) 1.14
Release of two vasodilators, adenosine and prostacyclin, from isolated rabbit hearts during controlled hypoxia. J Physiol (1983) 0.91
Left ventricular contractility and developed tension in the intact dog submitted to an intracoronary infusion of adenosine. J Physiol (1973) 0.90
Adenosine causes transient dilatation of coronary arteries in man. Br J Clin Pharmacol (1987) 0.90
Endogenous adenosine is an autacoid feedback inhibitor of chloride transport in the shark rectal gland. J Clin Invest (1991) 0.90
Adenosine: an importance beyond ATP. Br Med J (Clin Res Ed) (1986) 0.89
Protein synthesis in the isolated perfused rat heart. Effects of mechanical work load, diastolic ventricular pressure and coronary pressure on amino acid incorporation and its transmural distribution into left ventricular protein. Basic Res Cardiol (1981) 0.89
The mechanism of ammonia production and the effect of mechanical work load on proteolysis and amino acid catabolism in isolated perfused rat heart. Biochem J (1980) 0.87
Acute metabolic response in myocardial infarction. Br Heart J (1971) 0.84
Left ventricular performance and coronary flow after coronary embolization with plastic microspheres. J Clin Invest (1971) 0.82
The effect of anoxia on the ventricular fibrillation threshold in the rabbit isolated heart. Br J Pharmacol (1975) 0.79
A new procedure for haptenizing adenosine leading to a more specific radioimmunoassay method. Biochem J (1982) 0.77
Regional glucose uptake and protein synthesis in isolated perfused rat hearts immediately after training and later. Basic Res Cardiol (1987) 0.75
Effect of adenosine deaminase on myocardial reactive hyperemia: preliminary report. Basic Res Cardiol (1981) 0.75
Purine nucleoside efflux during myocardial ischemia in the pig. Basic Res Cardiol (1975) 0.75
Protection against infarction afforded by preconditioning is mediated by A1 adenosine receptors in rabbit heart. Circulation (1991) 4.30
Intravenous pretreatment with A1-selective adenosine analogues protects the heart against infarction. Circulation (1992) 2.08
8-Cyclopentyl-1,3-dipropylxanthine (DPCPX)--a selective high affinity antagonist radioligand for A1 adenosine receptors. Naunyn Schmiedebergs Arch Pharmacol (1987) 1.99
Evidence that the adenosine A3 receptor may mediate the protection afforded by preconditioning in the isolated rabbit heart. Cardiovasc Res (1994) 1.62
The A1 adenosine receptor. Identification of the binding subunit by photoaffinity cross-linking. J Biol Chem (1985) 1.52
Evaluation of novel tropane analogues in comparison with the binding characteristics of [18F]FP-CIT and [131I]beta-CIT. Nucl Med Biol (2007) 1.41
The A2A adenosine receptor mediates coronary vasodilation. J Pharmacol Exp Ther (1998) 1.40
Structure-activity relationships for N6-substituted adenosines at a brain A1-adenosine receptor with a comparison to an A2-adenosine receptor regulating coronary blood flow. Biochem Pharmacol (1986) 1.39
Ligand selectivity of dog coronary adenosine receptor resembles that of adenylate cyclase stimulatory (Ra) receptors. J Pharmacol Exp Ther (1983) 1.31
Evidence for an adenosine receptor on the surface of dog coronary myocytes. Circ Res (1976) 1.24
A simple, specific, radioisotopic assay for 5'-nucleotidase. Anal Biochem (1975) 1.24
Characterization of the A1 adenosine receptor-adenylate cyclase system of cerebral cortex using an agonist photoaffinity ligand. J Neurochem (1986) 1.21
Endothelial cell uptake of adenosine in canine skeletal muscle. Am J Physiol (1986) 1.16
Definition of subclasses of adenosine receptors associated with adenylate cyclase: interaction of adenosine analogs with inhibitory A1 receptors and stimulatory A2 receptors. Can J Physiol Pharmacol (1987) 1.16
Dog coronary artery adenosine receptor: structure of the N6-alkyl subregion. J Med Chem (1985) 1.11
Characterization of two affinity states of adenosine A2a receptors with a new radioligand, 2-[2-(4-amino-3-[125I]iodophenyl)ethylamino]adenosine. Mol Pharmacol (1995) 1.06
N6-substituted N-alkyladenosine-5'-uronamides: bifunctional ligands having recognition groups for A1 and A2 adenosine receptors. J Med Chem (1986) 1.06
2-Alkoxyadenosines: potent and selective agonists at the coronary artery A2 adenosine receptor. J Med Chem (1991) 1.02
N6-functionalized congeners of adenosine with high potency at A2-adenosine receptors: potential ligands for affinity chromatography. Biochem Biophys Res Commun (1986) 1.02
Histopathologic changes and small-bowel absorption in falciparum malaria. Am J Trop Med Hyg (1969) 1.00
Coronary vasoactivity of adenosine in the conscious dog. Circ Res (1979) 1.00
Metabolic control of coronary blood flow. Prog Cardiovasc Dis (1987) 0.98
Intracoronary adenosine deaminase reduces canine myocardial reactive hyperemia. Circ Res (1981) 0.98
Covalent binding of a selective agonist irreversibly activates guinea pig coronary artery A2 adenosine receptors. Naunyn Schmiedebergs Arch Pharmacol (1993) 0.94
Myocardial reactive hyperemia. Circ Res (1975) 0.93
Adenosine is not responsible for local metabolic control of coronary blood flow in dogs during exercise. Am J Physiol Heart Circ Physiol (2000) 0.92
Activity of N6-substituted 2-chloroadenosines at A1 and A2 adenosine receptors. J Med Chem (1991) 0.92
N6,9-disubstituted adenines: potent, selective antagonists at the A1 adenosine receptor. J Med Chem (1991) 0.91
Inhibition of platelet aggregation by adenosine receptor agonists. Naunyn Schmiedebergs Arch Pharmacol (1994) 0.91
Adenosine metabolism in canine myocardial reactive hyperemia. Circ Res (1978) 0.91
Adenosine uptake by canine heart. Circ Res (1972) 0.90
2-Phenylethoxy-9-methyladenine: an adenosine receptor antagonist that discriminates between A2 adenosine receptors in the aorta and the coronary vessels from the guinea pig. J Pharmacol Exp Ther (1993) 0.90
Structure-activity relationships for 2-substituted adenosines at A1 and A2 adenosine receptors. Pharmacology (1993) 0.90
Functional characterization of adenosine A2 receptors in Jurkat cells and PC12 cells using adenosine receptor agonists. Naunyn Schmiedebergs Arch Pharmacol (1996) 0.89
Adenosine analogs mediating depressant effects on synaptic transmission in rat hippocampus: structure-activity relationships for the N6 subregion. Naunyn Schmiedebergs Arch Pharmacol (1986) 0.89
Dog coronary artery adenosine receptor: structure of the N6-aryl subregion. J Med Chem (1986) 0.89
Substituted 1,3-dipropylxanthines as irreversible antagonists of A1 adenosine receptors. J Med Chem (1994) 0.87
Nitric oxide modulates coronary autoregulation in the guinea pig. Circ Res (1992) 0.87
Inhibition of rat ventricular automaticity by adenosine. Am J Physiol (1985) 0.87
Normal absorption in Thai subjects with non-specific jejunal abnormalities. Br Med J (1967) 0.86
2-(N'-alkylidenehydrazino)adenosines: potent and selective coronary vasodilators. J Med Chem (1992) 0.86
Cardiovascular actions of adenosines, but not adenosine receptors, differ in rat and guinea pig. Life Sci (1991) 0.84
Local factors regulating cardiac and skeletal muscle blood flow. Annu Rev Physiol (1981) 0.83
Adenosine stimulates phosphate and glucose transport in opossum kidney epithelial cells. Am J Physiol (1991) 0.83
Cyclic adenosine 3',5'-monophosphate-stimulated protein kinase and a substrate associated with cardiac sarcoplasmic reticulum. J Biol Chem (1973) 0.83
N6-substituted 9-methyladenines: a new class of adenosine receptor antagonists. FEBS Lett (1987) 0.82
Role of adenosine in coronary blood flow regulation after reductions in perfusion pressure. Circ Res (1985) 0.82
The anti-infarct effect of an adenosine A1-selective agonist is diminished after prolonged infusion as is the cardioprotective effect of ischaemic preconditioning in rabbit heart. J Mol Cell Cardiol (1994) 0.82
Adenosine's role in regulating basal coronary arteriolar tone. Am J Physiol (1986) 0.82
2-aralkoxyadenosines: potent and selective agonists at the coronary artery A2 adenosine receptor. J Med Chem (1991) 0.81
Ligand binding to the adenine analogue binding protein of the rabbit erythrocyte. Biochemistry (1978) 0.80
2-(N'-aralkylidenehydrazino)adenosines: potent and selective coronary vasodilators. J Med Chem (1992) 0.80
Upregulated renal adenosine A1 receptors augment PKC and glucose transport but inhibit proliferation. Am J Physiol (1996) 0.80
A radioligand-binding assay for adenosine in tissue extracts. Anal Biochem (1978) 0.80
Limitations in predicting oxyhemoglobin saturation of dog blood from PO2. Am J Physiol (1980) 0.79
Relationship of cardiac oxygen usage, adenosine content, and coronary resistance in dogs. Circ Res (1980) 0.79
Glibenclamide reduces the coronary vasoactivity of adenosine receptor agonists. J Pharmacol Exp Ther (1994) 0.79
Compartmentalization of the adenosine pool of dog and rat hearts. Circ Res (1982) 0.78
Metabolic regulation of coronary blood flow. Physiologist (1982) 0.78
Forskolin potentiates the coronary vasoactivity of adenosine in the open-chest dog. Circ Res (1984) 0.78
Role of adenosine in mediating myocardial blood flow response to isoproterenol: observations in closed chest, sedated, domestic swine. Cardiovasc Res (1986) 0.77
Coronary vasoactivity of acetate in dog and guinea-pig. Basic Res Cardiol (1986) 0.77
Role of adenosine in mediating the coronary vasodilative response to acute hypoxia. Cardiovasc Res (1987) 0.77
Selective A2-adenosine receptor agonists do not alter action potential duration, twitch shortening, or cAMP accumulation in guinea pig, rat, or rabbit isolated ventricular myocytes. Circ Res (1993) 0.77
Structure-activity relationship of 2-(ar) alkoxyadenosines at the adenosine A2 receptor in coronary artery. Eur J Pharmacol (1993) 0.77
Biological activity and a modified synthesis of 8-amino-3-beta-D-ribofuranosyl-1,2,4-triazolo[4,3-a]pyrazine, an isomer of formycin. J Med Chem (1984) 0.76
Effect of adenosine deaminase on myocardial reactive hyperemia: preliminary report. Basic Res Cardiol (1981) 0.75
Binding of tritiated and radioiodinated ZM241,385 to brain A2A adenosine receptors. Nucl Med Biol (2004) 0.75
Evaluation of radioiodinated 8-Cyclopentyl-3-[(E)-3-iodoprop-2-en-1-yl]-1-propylxanthine ([*I]CPIPX) as a new potential A1 adenosine receptor antagonist for SPECT. Nucl Med Biol (2003) 0.75
Pericardial superfusion to measure cardiac interstitial adenosine concentration. Am J Physiol (1983) 0.75
Role of adenosine in the maintenance of coronary vasodilation distal to a severe coronary artery stenosis. Observations in conscious domestic swine. Circ Res (1983) 0.75
Decrease in myocardial oxygen extraction with aortic constriction in the dog. Am J Physiol (1982) 0.75
Adenosine regulation of canine cardiac adenylate cyclase. Biochem Pharmacol (1981) 0.75
Myocardial: blood purine nucleoside concentration ratios in canine myocardium. Adv Exp Med Biol (1973) 0.75
Nature of the N6 region of the adenosine receptor in guinea-pig ileum and rat vas deferens. Naunyn Schmiedebergs Arch Pharmacol (1986) 0.75
Potency of N6 secondary and tertiary alkyladenosine analogues at presynaptic A1 adenosine receptors in guinea-pig ileum. J Auton Pharmacol (1991) 0.75
Change in coronary venous PO2 following myocardial infarction in unanesthetized dogs. J Surg Res (1983) 0.75
Phenyl(dihydroboryl) polyacrylamide beads for chromatography of ribonucleosides in tissue extracts. J Chromatogr (1979) 0.75
Coronary vasoactivity of adenosine covalently linked to polylysine. Life Sci (1977) 0.75
Exercise performance and hemodynamics during dietary potassium depletion in dogs. J Appl Physiol Respir Environ Exerc Physiol (1978) 0.75
Adenosine activation of a nuclear pool of protein kinase C in rat splenocytes. Life Sci (1990) 0.75
A1 adenosine receptor antagonists as ligands for positron emission tomography (PET) and single-photon emission tomography (SPET). J Med Chem (1998) 0.75
Potency of N6-modified N-alkyl adenosine-5'-uronamides at presynaptic adenosine receptors in guinea-pig ileum. Naunyn Schmiedebergs Arch Pharmacol (1987) 0.75
Natural history of potassium-deficiency myopathy in the dog: role of adrenocorticosteroid in rhabdomyolysis. J Lab Clin Med (1983) 0.75
Transient postocclusive renal vasospasm in conscious rhesus monkeys. Am J Physiol (1977) 0.75
An implantable semiconductor beta-radiation detector. Am J Physiol (1977) 0.75
Inquiry into hereditary factors in the pathogenesis of dengue haemorrhagic fever: a preliminary note. Bull World Health Organ (1966) 0.75
Adenosine metabolism: properties of dog heart microsomal 5'-nucleotidase. Adv Exp Med Biol (1973) 0.75
Steric requirements for binding of adenosine to a membrane carrier in canine heart. Biochim Biophys Acta (1973) 0.75
Asymptomatic hepatitis in adults given gamma-globulin for prophylaxis. Clinical and laboratory features. Arch Intern Med (1969) 0.75
Factors determining delayed peak flow in canine myocardial reactive hyperaemia. Cardiovasc Res (1979) 0.75