Published in Exp Mol Pathol on February 01, 1970
Oval cell proliferation and the origin of small hepatocytes in liver injury induced by D-galactosamine. Am J Pathol (1991) 2.31
Activation, proliferation, and differentiation of progenitor cells into hepatocytes in the D-galactosamine model of liver regeneration. Am J Pathol (1993) 1.88
Studies on the golgi apparatus. Cumulative inhibition of protein and glycoprotein secretion by D-galactosamine. Biochem J (1974) 1.59
Studies on rat liver plasma membrane. Altered protein and phospholipid metabolism after injection of D-galactosamine. Biochem J (1977) 1.50
Studies on hepatic uptake of antigen. II. The effect of hepatotoxins on the immune response. Immunology (1973) 0.97
Transcription factor and liver-specific mRNA expression in facultative epithelial progenitor cells of liver and pancreas. Am J Pathol (1995) 0.88
Amplified interactive toxicity of chemicals at nontoxic levels: mechanistic considerations and implications to public health. Environ Health Perspect (1994) 0.85
An ultrastructural and histochemical study of the prominent inflammatory response in D(+)-galactosamine hepatotoxicity. Br J Exp Pathol (1987) 0.81
Guanylate cyclase activity and cyclic nucleotide concentrations during liver regeneration after experimental injury. Biochem J (1977) 0.75
Energy conservation in chemotrophic anaerobic bacteria. Bacteriol Rev (1977) 30.41
Galactosamine-induced sensitization to the lethal effects of endotoxin. Proc Natl Acad Sci U S A (1979) 6.77
Requirement for lipopolysaccharide-responsive macrophages in galactosamine-induced sensitization to endotoxin. Infect Immun (1986) 3.42
Energy production in anaerobic organisms. Angew Chem Int Ed Engl (1970) 3.02
The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates. J Biol Chem (1994) 2.82
Galactosamine hepatitis: key role of the nucleotide deficiency period in the pathogenesis of cell injury and cell death. Rev Physiol Biochem Pharmacol (1974) 2.76
Function of reduced pyridine nucleotide-ferredoxin oxidoreductases in saccharolytic Clostridia. Biochim Biophys Acta (1973) 2.71
Experimental hepatitis induced by D-galactosamine. Exp Mol Pathol (1968) 2.47
A novel human organic anion transporting polypeptide localized to the basolateral hepatocyte membrane. Am J Physiol Gastrointest Liver Physiol (2000) 2.21
Hepatic uptake of bilirubin and its conjugates by the human organic anion transporter SLC21A6. J Biol Chem (2000) 2.06
Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance. Biochim Biophys Acta (1999) 1.99
Biochemical engineering of the N-acyl side chain of sialic acid: biological implications. Glycobiology (2001) 1.93
UDP-GlcNAc 2-epimerase: a regulator of cell surface sialylation. Science (1999) 1.88
A bifunctional enzyme catalyzes the first two steps in N-acetylneuraminic acid biosynthesis of rat liver. Purification and characterization of UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase. J Biol Chem (1997) 1.88
Localization and genomic organization of a new hepatocellular organic anion transporting polypeptide. J Biol Chem (2000) 1.85
Drug resistance and ATP-dependent conjugate transport mediated by the apical multidrug resistance protein, MRP2, permanently expressed in human and canine cells. Mol Pharmacol (1999) 1.84
The rat canalicular conjugate export pump (Mrp2) is down-regulated in intrahepatic and obstructive cholestasis. Gastroenterology (1997) 1.83
The contraction of hepatic stellate (Ito) cells stimulated with vasoactive substances. Possible involvement of endothelin 1 and nitric oxide in the regulation of the sinusoidal tonus. Eur J Biochem (1993) 1.80
The multidrug resistance protein 5 functions as an ATP-dependent export pump for cyclic nucleotides. J Biol Chem (2000) 1.76
ATP-dependent transport of glutathione S-conjugates by the multidrug resistance-associated protein. Cancer Res (1994) 1.73
The energy metabolism of Clostridium kluyveri. Eur J Biochem (1968) 1.72
Transport of glutathione, glucuronate, and sulfate conjugates by the MRP gene-encoded conjugate export pump. Cancer Res (1996) 1.69
cDNA cloning of the hepatocyte canalicular isoform of the multidrug resistance protein, cMrp, reveals a novel conjugate export pump deficient in hyperbilirubinemic mutant rats. J Biol Chem (1996) 1.66
Biosynthesis of a nonphysiological sialic acid in different rat organs, using N-propanoyl-D-hexosamines as precursors. J Biol Chem (1992) 1.59
Inhibition by cyclosporin A of adenosine triphosphate-dependent transport from the hepatocyte into bile. Gastroenterology (1993) 1.58
The proption of the incorporation of leucine into albumin to that into totaprotein in rat liver and hepatoma Morris 5123 TC. Eur J Biochem (1969) 1.50
On the pathogenesis of galactosamine hepatitis. Indications of extrahepatocellular mechanisms responsible for liver cell death. Virchows Arch B Cell Pathol (1978) 1.46
ATP-dependent transport of bilirubin glucuronides by the multidrug resistance protein MRP1 and its hepatocyte canalicular isoform MRP2. Biochem J (1997) 1.44
Stability of the replicative Mcm3 protein in proliferating and differentiating human cells. Exp Cell Res (1998) 1.43
Emerging transporters of clinical importance: an update from the International Transporter Consortium. Clin Pharmacol Ther (2013) 1.42
Biosynthetic modulation of sialic acid-dependent virus-receptor interactions of two primate polyoma viruses. J Biol Chem (1995) 1.40
Production of tumor necrosis factor-alpha, interleukin-1 and interleukin-6 in the perfused rat liver. Eur Cytokine Netw (1994) 1.40
Absence of the canalicular isoform of the MRP gene-encoded conjugate export pump from the hepatocytes in Dubin-Johnson syndrome. Hepatology (1996) 1.36
The appearance of D-galactosamine-induced hepatitis and generalized edema in adrenalectomized rats. Beitr Pathol (1975) 1.34
ATP-dependent primary active transport of cysteinyl leukotrienes across liver canalicular membrane. Role of the ATP-dependent transport system for glutathione S-conjugates. J Biol Chem (1990) 1.32
Evidence for efficient uptake and incorporation of sialic acid by eukaryotic cells. Eur J Biochem (2001) 1.32
Regulation of synthesis and secretion of major rat acute-phase proteins by recombinant human interleukin-6 (BSF-2/IL-6) in hepatocyte primary cultures. Eur J Biochem (1988) 1.31
Expression and immunolocalization of the multidrug resistance proteins, MRP1-MRP6 (ABCC1-ABCC6), in human brain. Neuroscience (2004) 1.30
Enzymic determination of uracil nucleotides in tissues. Anal Biochem (1970) 1.30
ATP-dependent glutathione disulphide transport mediated by the MRP gene-encoded conjugate export pump. Biochem J (1996) 1.29
Selective uridine triphosphate deficiency induced by D-galactosamine in liver and reversed by pyrimidine nucleotide precursors. Effect on ribonucleic acid synthesis. J Biol Chem (1974) 1.28
Liver-intestine cadherin: molecular cloning and characterization of a novel Ca(2+)-dependent cell adhesion molecule expressed in liver and intestine. J Cell Biol (1994) 1.28
Activation of gene transcription by prostacyclin analogues is mediated by the peroxisome-proliferators-activated receptor (PPAR). Eur J Biochem (1996) 1.28
1-deoxynojirimycin impairs oligosaccharide processing of alpha 1-proteinase inhibitor and inhibits its secretion in primary cultures of rat hepatocytes. J Biol Chem (1983) 1.27
Exocytosis of active cathepsin B enzyme activity at pH 7.0, inhibition and molecular mass. Eur J Biochem (1999) 1.27
The secretion of serum protein and the synthesis of albumin and total protein in regenerating rat liver. J Biol Chem (1971) 1.26
Molecular cloning and characterization of murine and human N-acetylglucosamine kinase. Eur J Biochem (2000) 1.25
Direct evidence for the binding of rat liver DPP IV to collagen in vitro. Exp Cell Res (1988) 1.24
Superoxide release by zymosan-stimulated rat Kupffer cells in vitro. Eur J Biochem (1981) 1.23
Expression of the multidrug resistance proteins MRP2 and MRP3 in human hepatocellular carcinoma. Int J Cancer (2001) 1.23
Up-regulation of basolateral multidrug resistance protein 3 (Mrp3) in cholestatic rat liver. Hepatology (2001) 1.22
Structural analysis and molybdenum-dependent expression of the pAO1-encoded nicotine dehydrogenase genes of Arthrobacter nicotinovorans. Mol Microbiol (1994) 1.22
Regulation of the reduced nicotinamide adenine dinucleotide phosphate-ferredoxin reductase system in Clostridium kluyveri. J Biol Chem (1971) 1.22
Studies on the mechanism of galactosamine-1-phosphate and its inhibition of UDP-glucose pyrophosphorylase. Eur J Biochem (1969) 1.22
Characterization of the human multidrug resistance protein isoform MRP3 localized to the basolateral hepatocyte membrane. Hepatology (1999) 1.20
Contribution of clinical breast examination to mammography screening in the early detection of breast cancer. J Med Screen (2003) 1.20
Eicosanoid-mediated contractility of hepatic stellate cells. Biochem J (1992) 1.20
Expression of the MRP gene-encoded conjugate export pump in liver and its selective absence from the canalicular membrane in transport-deficient mutant hepatocytes. J Cell Biol (1995) 1.20
Hereditary defect of hepatobiliary cysteinyl leukotriene elimination in mutant rats with defective hepatic anion excretion. Hepatology (1987) 1.19
Characterization of the ATP-dependent leukotriene C4 export carrier in mastocytoma cells. Eur J Biochem (1994) 1.19
Regulation of the reduced nicotinamide adenine dinucleotide-ferredoxin reductase system in Clostridium kluyveri. J Biol Chem (1971) 1.19
6-Hydroxy-D-nicotine oxidase of Arthrobacter oxidans. Gene structure of the flavoenzyme and its relationship to 6-hydroxy-L-nicotine oxidase. Eur J Biochem (1987) 1.18
ATP-dependent transport of taurocholate across the hepatocyte canalicular membrane mediated by a 110-kDa glycoprotein binding ATP and bile salt. J Biol Chem (1991) 1.18
Tauroursodeoxycholic acid inserts the apical conjugate export pump, Mrp2, into canalicular membranes and stimulates organic anion secretion by protein kinase C-dependent mechanisms in cholestatic rat liver. Hepatology (2001) 1.18
Leukotrienes as mediators in ischemia-reperfusion injury in a microcirculation model in the hamster. J Clin Invest (1991) 1.17
Expression of the conjugate export pump encoded by the mrp2 gene in the apical membrane of kidney proximal tubules. J Am Soc Nephrol (1997) 1.17
Cyclic AMP stimulates sorting of the canalicular organic anion transporter (Mrp2/cMoat) to the apical domain in hepatocyte couplets. J Cell Sci (1998) 1.16
Isolation and partial characterization of plasmid DNA from Arthrobacter oxidans. Arch Microbiol (1984) 1.16
Biochemical engineering of neural cell surfaces by the synthetic N-propanoyl-substituted neuraminic acid precursor. J Biol Chem (1998) 1.16
Synthesis of prostanoids and cyclic nucleotides by phagocytosing rat Kupffer cells. Eur J Biochem (1984) 1.15
Vectorial transport by double-transfected cells expressing the human uptake transporter SLC21A8 and the apical export pump ABCC2. Mol Pharmacol (2001) 1.14
Staphylococcal enterotoxin B as a nonimmunological mast cell stimulus in primates: the role of endogenous cysteinyl leukotrienes. Int Arch Allergy Appl Immunol (1987) 1.14
The dependence of glucose formation from lactate on the adenosine triphosphate content in the isolated perfused rat liver. Biochim Biophys Acta (1975) 1.11
Galactosamine induced liver injury. Prog Liver Dis (1972) 1.10
Selective loss of either the epimerase or kinase activity of UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase due to site-directed mutagenesis based on sequence alignments. J Biol Chem (1999) 1.10
Protein degradation in the plasma membrane of regenerating liver and Morris hepatomas. Eur J Biochem (1978) 1.10
The multidrug resistance protein MRP1 mediates the release of glutathione disulfide from rat astrocytes during oxidative stress. J Neurochem (2001) 1.09
Purification and characterization of N-acetylglucosamine kinase from rat liver--comparison with UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase. Eur J Biochem (1998) 1.09
Different half-lives of the carbohydrate and protein moieties of a 110,000-dalton glycoprotein isolated from plasma membranes of rat liver. Proc Natl Acad Sci U S A (1980) 1.09
Consequences of a subtle sialic acid modification on the murine polyomavirus receptor. J Virol (1997) 1.08
Involvement of plasma membrane dipeptidyl peptidase IV in fibronectin-mediated adhesion of cells on collagen. Biol Chem Hoppe Seyler (1985) 1.07
Metabolism and analysis of cysteinyl leukotrienes in the monkey. J Biol Chem (1986) 1.07
How many general surgeons do you need in rural areas? Three approaches to physician resource planning in southern Manitoba. CMAJ (1996) 1.07
The synthesis of one-carbon units from CO2 in Clostridium kluyveri. Eur J Biochem (1968) 1.07
Hydrogen formation from NADH in cell-free extracts of Clostridium kluyveri. Acetyl coenzyme A requirement and ferredoxin dependence. FEBS Lett (1969) 1.07
Rat hepatic sinusoidal endothelial cells in monolayer culture. Biochemical and ultrastructural characteristics. J Hepatol (1988) 1.07
The cysteine-rich region of dipeptidyl peptidase IV (CD 26) is the collagen-binding site. Biochem Biophys Res Commun (1995) 1.07
Cholestasis caused by inhibition of the adenosine triphosphate-dependent bile salt transport in rat liver. Gastroenterology (1994) 1.06
Induction and purification of stereospecific nicotine oxidizing enzymes from Arthrobacter oxidans. Biochim Biophys Acta (1965) 1.06