Published in Lab Invest on June 01, 1970
Inhibition of microsomal oxidation of ethanol by pyrazole and 4-methylpyrazole in vitro. Increased effectiveness after induction by pyrazole and 4-methylpyrazole. Biochem J (1986) 1.15
Inhibition of liver regeneration by chronic alcohol administration. Gut (1982) 1.10
The effect of ethanol on drug oxidations in vitro and the significance of ethanol-cytochrome P-450 interaction. Biochem J (1973) 1.02
Induction of 5-aminolaevulinate synthase by two- to five-carbon alcohols in cultured chick-embryo hepatocytes. Relationship to induction of cytochrome P-450. Biochem J (1986) 0.83
A human PBPK model for ethanol describing inhibition of gastric motility. J Mol Histol (2004) 0.81
Monooxygenase enzyme activity in alcoholics with varying degrees of liver damage. Gut (1979) 0.75
Effects of acute ethanol administration on rat liver 5-aminolaevulinate synthase activity. Biochem J (1989) 0.75
Hepatic metabolism in ethanol-treated young rats. Z Ernahrungswiss (1979) 0.75
Effects of ethanol on drug metabolism in the liver. Trans Am Clin Climatol Assoc (1974) 0.75
High blood alcohol levels in women. The role of decreased gastric alcohol dehydrogenase activity and first-pass metabolism. N Engl J Med (1990) 6.67
Effects of ranitidine on blood alcohol levels after ethanol ingestion. Comparison with other H2-receptor antagonists. JAMA (1992) 3.68
The effects of alcoholism on skeletal and cardiac muscle. N Engl J Med (1989) 2.40
The feeding of alcohol in liquid diets: two decades of applications and 1982 update. Alcohol Clin Exp Res (1982) 2.37
Gender differences in pharmacokinetics of alcohol. Alcohol Clin Exp Res (2001) 2.32
Fatty liver in the rat after prolonged intake of ethanol with a nutritionally adequate new liquid diet. J Nutr (1967) 2.23
Primary pulmonary hypertension. Vascular structure, morphometry, and responsiveness to vasodilator agents. Circulation (1989) 2.16
The Behavior Rating Scale for Dementia of the Consortium to Establish a Registry for Alzheimer's Disease. The Behavioral Pathology Committee of the Consortium to Establish a Registry for Alzheimer's Disease. Am J Psychiatry (1995) 2.11
Relationship of students' perceptions of faculty to scholastic achievement: are popular instructors better educators? Hum Pathol (1997) 2.03
Interaction of calcium with microsomes: a modified method for the rapid isolation of rat liver microsomes. Biochem Biophys Res Commun (1972) 2.00
Hepatic microsomal ethanol-oxidizing system. In vitro characteristics and adaptive properties in vivo. J Biol Chem (1970) 1.95
Pathogenesis and early diagnosis of alcoholic liver injury. N Engl J Med (1978) 1.93
Acetaminophen activation by human liver cytochromes P450IIE1 and P450IA2. Arch Biochem Biophys (1989) 1.89
Hepatic microsomal enzymes in man and rat: induction and inhibition by ethanol. Science (1968) 1.84
Sputum examination for the diagnosis of Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome. Am Rev Respir Dis (1986) 1.84
Effects of cimetidine on gastric alcohol dehydrogenase activity and blood ethanol levels. Gastroenterology (1989) 1.66
Alcohol-induced hepatic injury in nonalcoholic volunteers. N Engl J Med (1968) 1.65
Fatty liver, alcoholic hepatitis and cirrhosis produced by alcohol in primates. N Engl J Med (1974) 1.63
High blood acetaldehyde levels after ethanol administration. Difference between alcoholic and nonalcoholic subjects. N Engl J Med (1975) 1.54
Protein 4.1R-deficient mice are viable but have erythroid membrane skeleton abnormalities. J Clin Invest (1999) 1.53
Asperger's disorder. Am J Psychiatry (2000) 1.52
Alcoholic liver injury in baboons: transformation of lipocytes to transitional cells. Gastroenterology (1984) 1.51
Metabolism of alcohol by human gastric cells: relation to first-pass metabolism. Gastroenterology (1996) 1.49
Ethanol consumption inhibits fetal DNA methylation in mice: implications for the fetal alcohol syndrome. Alcohol Clin Exp Res (1991) 1.47
The virtues of extended matching and uncued tests as alternatives to multiple choice questions. Hum Pathol (1997) 1.46
Role of dietary, adipose, and endogenously synthesized fatty acids in the pathogenesis of the alcoholic fatty liver. J Clin Invest (1966) 1.44
beta-Carotene beadlets potentiate hepatotoxicity of alcohol. Am J Clin Nutr (1997) 1.44
Potential gene therapy for lecithin-cholesterol acyltransferase (LCAT)-deficient and hypoalphalipoproteinemic patients with adenovirus-mediated transfer of human LCAT gene. Circulation (1996) 1.43
Interactive effects of dietary protein and ethanol on rat pancreas. Protein synthesis and enzyme secretion. Gastroenterology (1990) 1.43
Effects of ethanol on lipid metabolism. J Lipid Res (1979) 1.43
The ultrastructure of fatty liver induced by prolonged ethanol ingestion. Am J Pathol (1966) 1.42
Dilinoleoylphosphatidylcholine selectively modulates lipopolysaccharide-induced Kupffer cell activation. J Lab Clin Med (1999) 1.42
Effect of omeprazole on gastric first-pass metabolism of ethanol. Dig Dis Sci (1992) 1.42
Very low dose alpha-2b interferon for the treatment of hairy cell leukemia. Blood (1989) 1.41
Effect of alcohol (ethanol) administration on sex-hormone metabolism in normal men. N Engl J Med (1976) 1.41
Microbial degradation of oil spills enhanced by a slow-release fertilizer. Appl Environ Microbiol (1976) 1.41
Gastric juice urease activity as a diagnostic test for Helicobacter pylori infection. Am J Gastroenterol (1997) 1.40
Alcohol, vitamin A, and beta-carotene: adverse interactions, including hepatotoxicity and carcinogenicity. Am J Clin Nutr (1999) 1.40
Metabolism of ethanol in rat gastric cells and its inhibition by cimetidine. Gastroenterology (1995) 1.39
Tolerance and cross-tolerance in chronic alcoholics: reduced membrane binding of ethanol and other drugs. Science (1981) 1.39
Hematologic effects of alcohol in man in the absence of nutritional deficiency. N Engl J Med (1969) 1.37
Inhibition of drug metabolism by acute ethanol intoxication. A hepatic microsomal mechanism. Am J Med (1970) 1.36
Alcoholic myopathy in heart and skeletal muscle. N Engl J Med (1979) 1.36
The modulation of protein kinase C activity by membrane lipid bilayer structure. J Biol Chem (1994) 1.33
Depressed hepatic glutathione and increased diene conjugates in alcoholic liver disease. Evidence of lipid peroxidation. Dig Dis Sci (1983) 1.33
Hepatic injury in chronic hypervitaminosis A. Am J Dis Child (1970) 1.33
Perivenular fibrosis in alcoholic liver injury: ultrastructure and histologic progression. Gastroenterology (1982) 1.32
Sequential production of fatty liver, hepatitis, and cirrhosis in sub-human primates fed ethanol with adequate diets. Proc Natl Acad Sci U S A (1975) 1.29
Early perivenular sclerosis in alcoholic fatty liver: an index of progressive liver injury. Gastroenterology (1977) 1.28
To drink (moderately) or not to drink? N Engl J Med (1984) 1.27
The greater risk of alcoholic cardiomyopathy and myopathy in women compared with men. JAMA (1995) 1.26
A randomized study of tiotropium Respimat Soft Mist inhaler vs. ipratropium pMDI in COPD. Respir Med (2007) 1.26
The feeding of ethanol in liquid diets. Alcohol Clin Exp Res (1986) 1.25
Ionizing radiation activates transcription of the EGR1 gene via CArG elements. Proc Natl Acad Sci U S A (1992) 1.25
Ethanol oxidation by hepatic microsomes: adaptive increase after ethanol feeding. Science (1968) 1.24
The intralobular distribution of ethanol-inducible P450IIE1 in rat and human liver. Hepatology (1989) 1.24
Models of alcoholic liver disease in rodents: a critical evaluation. Alcohol Clin Exp Res (2001) 1.23
Increase of ethanol, meprobamate and pentobarbital metabolism after chronic ethanol administration in man and in rats. Am J Med (1971) 1.22
Lipocytes and transitional cells in alcoholic liver disease: a morphometric study. Hepatology (1988) 1.22
Opposite regulation of human versus mouse apolipoprotein A-I by fibrates in human apolipoprotein A-I transgenic mice. J Clin Invest (1996) 1.22
Alcoholic fatty liver in man on a high protein and low fat diet. Am J Med (1968) 1.20
Ethanol increases hepatic smooth endoplasmic reticulum and drug-metabolizing enzymes. Science (1968) 1.20
Quantitative relationship between amount of dietary fat and severity of alcoholic fatty liver. Am J Clin Nutr (1970) 1.19
The relation of alcoholic myopathy to cardiomyopathy. Ann Intern Med (1994) 1.19
Alcoholism, alcohol, and drugs. Science (1971) 1.18
Histogenesis of alcoholic fibrosis and cirrhosis in the baboon. Am J Pathol (1980) 1.18
Ethanol produces muscle damage in human volunteers. Science (1972) 1.18
Inhibition of protein kinase C by alcohols and anaesthetics. Nature (1993) 1.18
Glutamate dehydrogenase: a reliable marker of liver cell necrosis in the alcoholic. Br Med J (1977) 1.17
Role of pRB dephosphorylation in cell cycle regulation. Front Biosci (2000) 1.17
Effects of chronic ethanol intoxication on oxidative phosphorylation in rat liver submitochondrial particles. J Biol Chem (1979) 1.17
Ethanol-induced mobilization of calcium by activation of phosphoinositide-specific phospholipase C in intact hepatocytes. J Biol Chem (1987) 1.17
Mammalian collagenase increases in early alcoholic liver disease and decreases with cirrhosis. Life Sci (1982) 1.16
Membranes and phospholipids of liver mitochondria from chronic alcoholic rats are resistant to membrane disordering by alcohol. Proc Natl Acad Sci U S A (1981) 1.15
Method of acetaldehyde measurement with minimal artifactual formation in red blood cells and plasma of actively drinking subjects with alcoholism. J Lab Clin Med (1992) 1.14
Effects of prolonged ethanol intake in man: role of dietary adipose, and endogenously synthesized fatty acids in the pathogenesis of the alcoholic fatty liver. J Clin Invest (1966) 1.14
Induction of cytochrome P-4502E1 in the human liver by ethanol is caused by a corresponding increase in encoding messenger RNA. Hepatology (1993) 1.14
Hepatic collagen metabolism: effect of alcohol consumption in rats and baboons. Science (1972) 1.14
The evolution of human cirrhosis deduced from observations in experimental animals. Medicine (Baltimore) (1967) 1.14
Pathogenesis of alcohol-induced accumulation of protein in the liver. J Clin Invest (1977) 1.13
Acetaldehyde selectively stimulates collagen production in cultured rat liver fat-storing cells but not in hepatocytes. Hepatology (1990) 1.12
Induction of cytochrome P450IIE1 in the obese overfed rat. Mol Pharmacol (1991) 1.12
Effects of fasting and chronic alcohol consumption on the first-pass metabolism of ethanol. Gastroenterology (1987) 1.12
Ultrastructural alterations in human hepatocytes following ingestion of ethanol with adequate diets. Am J Pathol (1966) 1.12
Ultrastructural changes in the small intestine induced by ethanol. Gastroenterology (1972) 1.12
Activation of Src-like p56/p53lyn tyrosine kinase by ionizing radiation. J Biol Chem (1994) 1.11
Effects of ethanol on the chemical and structural properties of biologic membranes. Lab Invest (1985) 1.11
Characterization of three highly purified cytochromes P-450 from hepatic microsomes of adult male rats. J Biol Chem (1984) 1.11