Published in Am J Clin Nutr on April 01, 1970
Dietary composition and nonalcoholic fatty liver disease. Dig Dis Sci (2004) 1.46
The effect of acute and prolonged ethanol treatment on the contents of coenzyme A, carnitine and their derivatives in rat liver. Biochem J (1973) 1.22
Rodent models of alcoholic liver disease: of mice and men. Alcohol (2012) 1.11
Abnormal polyunsaturated fatty acid patterns of serum lipids in alcoholism and cirrhosis: arachidonic acid deficiency in cirrhosis. Proc Natl Acad Sci U S A (1985) 1.11
Pathogenesis of alcoholic liver disease: the role of nuclear receptors. Exp Biol Med (Maywood) (2010) 1.00
Selective reduction of delta 6 and delta 5 desaturase activities but not delta 9 desaturase in micropigs chronically fed ethanol. J Clin Invest (1994) 0.95
Chronic ethanol consumption selectively stimulates rectal cell proliferation in the rat. Gut (1986) 0.91
Chronic alcohol feeding inhibits atherogenesis in C57BL/6 hyperlipidemic mice. Am J Pathol (1995) 0.87
Metabolism of palmitate in perfused rat liver. Effect of ethanol in livers from rats fed on a high-fat diet with or without ethanol. Biochem J (1979) 0.86
Enhancement of ethanol induced rectal mucosal hyper regeneration with age in F344 rats. Gut (1994) 0.86
Increased dietary fat contributes to dysregulation of the LKB1/AMPK pathway and increased damage in a mouse model of early-stage ethanol-mediated steatosis. J Nutr Biochem (2013) 0.84
Effect of prolonged ethanol ingestion on hepatic lipogenesis and related enzyme activities. Biochem J (1977) 0.84
Alcohol-induced ovarian failure in the rat. J Clin Invest (1978) 0.82
Ethanol--its nephrotoxic effect in the rat. Am J Pathol (1977) 0.81
Chronic alcohol consumption enhances iNKT cell maturation and activation. Toxicol Appl Pharmacol (2014) 0.80
Pyruvate carboxylation in the rat heart. Role of biotin-dependent enzymes. Biochem J (1989) 0.80
Vitamin B6 metabolism in chronic alcohol abuse The effect of ethanol oxidation on hepatic pyridoxal 5'-phosphate metabolism. J Clin Invest (1975) 0.79
Pharmacological attenuation of chronic alcoholic pancreatitis induced hypersensitivity in rats. World J Gastroenterol (2015) 0.79
Acetaldehyde-derived advanced glycation end-products promote alcoholic liver disease. PLoS One (2013) 0.77
Structure, function and metabolism of hepatic and adipose tissue lipid droplets: implications in alcoholic liver disease. Curr Mol Pharmacol (2015) 0.75
High blood alcohol levels in women. The role of decreased gastric alcohol dehydrogenase activity and first-pass metabolism. N Engl J Med (1990) 6.67
Effects of ranitidine on blood alcohol levels after ethanol ingestion. Comparison with other H2-receptor antagonists. JAMA (1992) 3.68
The feeding of alcohol in liquid diets: two decades of applications and 1982 update. Alcohol Clin Exp Res (1982) 2.37
Gender differences in pharmacokinetics of alcohol. Alcohol Clin Exp Res (2001) 2.32
Fatty liver in the rat after prolonged intake of ethanol with a nutritionally adequate new liquid diet. J Nutr (1967) 2.23
Liquid diet technique of ethanol administration: 1989 update. Alcohol Alcohol (1989) 2.09
Hepatic microsomal ethanol-oxidizing system. In vitro characteristics and adaptive properties in vivo. J Biol Chem (1970) 1.95
Pathogenesis and early diagnosis of alcoholic liver injury. N Engl J Med (1978) 1.93
Acetaminophen activation by human liver cytochromes P450IIE1 and P450IA2. Arch Biochem Biophys (1989) 1.89
Hepatic microsomal enzymes in man and rat: induction and inhibition by ethanol. Science (1968) 1.84
Phosphatidylcholine protects against fibrosis and cirrhosis in the baboon. Gastroenterology (1994) 1.76
Hepatotoxicity of ethanol. J Hepatol (1991) 1.69
Effects of cimetidine on gastric alcohol dehydrogenase activity and blood ethanol levels. Gastroenterology (1989) 1.66
Alcohol-induced hepatic injury in nonalcoholic volunteers. N Engl J Med (1968) 1.65
Fatty liver, alcoholic hepatitis and cirrhosis produced by alcohol in primates. N Engl J Med (1974) 1.63
Experimental methods of ethanol administration. Hepatology (1989) 1.57
High blood acetaldehyde levels after ethanol administration. Difference between alcoholic and nonalcoholic subjects. N Engl J Med (1975) 1.54
Alcoholic liver injury in baboons: transformation of lipocytes to transitional cells. Gastroenterology (1984) 1.51
Metabolism of alcohol by human gastric cells: relation to first-pass metabolism. Gastroenterology (1996) 1.49
Ethanol consumption inhibits fetal DNA methylation in mice: implications for the fetal alcohol syndrome. Alcohol Clin Exp Res (1991) 1.47
Role of dietary, adipose, and endogenously synthesized fatty acids in the pathogenesis of the alcoholic fatty liver. J Clin Invest (1966) 1.44
beta-Carotene beadlets potentiate hepatotoxicity of alcohol. Am J Clin Nutr (1997) 1.44
Interactive effects of dietary protein and ethanol on rat pancreas. Protein synthesis and enzyme secretion. Gastroenterology (1990) 1.43
Effects of ethanol on lipid metabolism. J Lipid Res (1979) 1.43
The ultrastructure of fatty liver induced by prolonged ethanol ingestion. Am J Pathol (1966) 1.42
Dilinoleoylphosphatidylcholine selectively modulates lipopolysaccharide-induced Kupffer cell activation. J Lab Clin Med (1999) 1.42
Effect of omeprazole on gastric first-pass metabolism of ethanol. Dig Dis Sci (1992) 1.42
Effect of alcohol (ethanol) administration on sex-hormone metabolism in normal men. N Engl J Med (1976) 1.41
Gastric juice urease activity as a diagnostic test for Helicobacter pylori infection. Am J Gastroenterol (1997) 1.40
Alcohol, vitamin A, and beta-carotene: adverse interactions, including hepatotoxicity and carcinogenicity. Am J Clin Nutr (1999) 1.40
Metabolism of ethanol in rat gastric cells and its inhibition by cimetidine. Gastroenterology (1995) 1.39
S-adenosyl-L-methionine attenuates alcohol-induced liver injury in the baboon. Hepatology (1990) 1.39
Hematologic effects of alcohol in man in the absence of nutritional deficiency. N Engl J Med (1969) 1.37
Inhibition of drug metabolism by acute ethanol intoxication. A hepatic microsomal mechanism. Am J Med (1970) 1.36
Depressed hepatic glutathione and increased diene conjugates in alcoholic liver disease. Evidence of lipid peroxidation. Dig Dis Sci (1983) 1.33
Animal models of chronic ethanol toxicity. Methods Enzymol (1994) 1.32
Perivenular fibrosis in alcoholic liver injury: ultrastructure and histologic progression. Gastroenterology (1982) 1.32
Sequential production of fatty liver, hepatitis, and cirrhosis in sub-human primates fed ethanol with adequate diets. Proc Natl Acad Sci U S A (1975) 1.29
Early perivenular sclerosis in alcoholic fatty liver: an index of progressive liver injury. Gastroenterology (1977) 1.28
To drink (moderately) or not to drink? N Engl J Med (1984) 1.27
The feeding of ethanol in liquid diets. Alcohol Clin Exp Res (1986) 1.25
Ethanol oxidation by hepatic microsomes: adaptive increase after ethanol feeding. Science (1968) 1.24
The intralobular distribution of ethanol-inducible P450IIE1 in rat and human liver. Hepatology (1989) 1.24
Models of alcoholic liver disease in rodents: a critical evaluation. Alcohol Clin Exp Res (2001) 1.23
Increase of ethanol, meprobamate and pentobarbital metabolism after chronic ethanol administration in man and in rats. Am J Med (1971) 1.22
Lipocytes and transitional cells in alcoholic liver disease: a morphometric study. Hepatology (1988) 1.22
Alcoholic fatty liver in man on a high protein and low fat diet. Am J Med (1968) 1.20
Ethanol increases hepatic smooth endoplasmic reticulum and drug-metabolizing enzymes. Science (1968) 1.20
Alcoholism, alcohol, and drugs. Science (1971) 1.18
Histogenesis of alcoholic fibrosis and cirrhosis in the baboon. Am J Pathol (1980) 1.18
Glutamate dehydrogenase: a reliable marker of liver cell necrosis in the alcoholic. Br Med J (1977) 1.17
Mammalian collagenase increases in early alcoholic liver disease and decreases with cirrhosis. Life Sci (1982) 1.16
Method of acetaldehyde measurement with minimal artifactual formation in red blood cells and plasma of actively drinking subjects with alcoholism. J Lab Clin Med (1992) 1.14
Induction of cytochrome P-4502E1 in the human liver by ethanol is caused by a corresponding increase in encoding messenger RNA. Hepatology (1993) 1.14
Hepatic collagen metabolism: effect of alcohol consumption in rats and baboons. Science (1972) 1.14
Effects of prolonged ethanol intake in man: role of dietary adipose, and endogenously synthesized fatty acids in the pathogenesis of the alcoholic fatty liver. J Clin Invest (1966) 1.14
Pathogenesis of alcohol-induced accumulation of protein in the liver. J Clin Invest (1977) 1.13
Acetaldehyde selectively stimulates collagen production in cultured rat liver fat-storing cells but not in hepatocytes. Hepatology (1990) 1.12
Induction of cytochrome P450IIE1 in the obese overfed rat. Mol Pharmacol (1991) 1.12
Effects of fasting and chronic alcohol consumption on the first-pass metabolism of ethanol. Gastroenterology (1987) 1.12
Ultrastructural changes in the small intestine induced by ethanol. Gastroenterology (1972) 1.12
Ultrastructural alterations in human hepatocytes following ingestion of ethanol with adequate diets. Am J Pathol (1966) 1.12
Early fine structural changes in the human liver induced by alcohol. Gastroenterology (1967) 1.11
Characterization of three highly purified cytochromes P-450 from hepatic microsomes of adult male rats. J Biol Chem (1984) 1.11
Desmin distinguishes cultured fat-storing cells from myofibroblasts, smooth muscle cells and fibroblasts in the rat. J Hepatol (1988) 1.11
Role of acetate in the reduction of plasma free fatty acids produced by ethanol in man. J Lipid Res (1968) 1.10
Acetaldehyde increases procollagen type I and fibronectin gene transcription in cultured rat fat-storing cells through a protein synthesis-dependent mechanism. Hepatology (1991) 1.10
Liver adaptation and injury in alcoholism. N Engl J Med (1973) 1.10
Alcoholic hepatomegaly: accumulation of protein in the liver. Science (1975) 1.10
Effect of alcohol on growth, bone density and muscle magnesium in the rat. J Nutr (1965) 1.09
Hepatic vitamin A depletion in alcoholic liver injury. N Engl J Med (1982) 1.09
Experimental alcoholic hepatic injury in man: ultrastructural changes. Fed Proc (1967) 1.08
Chronic alcoholic hepatic injury in experimental animals and man: biochemical pathways and nutritional factors. Fed Proc (1967) 1.08
The role of the hepatic microsomal ethanol oxidizing system (MEOS) for ethanol metabolism in vivo. J Pharmacol Exp Ther (1972) 1.08
Effect of ethanol on ketone metabolism. J Clin Invest (1970) 1.08
Differential depletion of carotenoids and tocopherol in liver disease. Hepatology (1993) 1.07
An experimental model of alcohol feeding and liver injury in the baboon. J Med Primatol (1974) 1.07
Alcoholism is associated with hepatitis C but not hepatitis B in an urban population. Am J Gastroenterol (1996) 1.05
Alcohol-induced gastric and duodenal lesions in man. Am J Gastroenterol (1978) 1.05
Role of intestinal bacterial overgrowth in ethanol production and metabolism in rats. Gastroenterology (1986) 1.05
Role of S-adenosyl-L-methionine in the treatment of liver diseases. J Hepatol (1999) 1.05
Polyunsaturated lecithin prevents acetaldehyde-mediated hepatic collagen accumulation by stimulating collagenase activity in cultured lipocytes. Hepatology (1992) 1.05
Ethanol--a hepatotoxic drug. Gastroenterology (1968) 1.04
Metabolism of retinol and retinoic acid by human liver cytochrome P450IIC8. Arch Biochem Biophys (1989) 1.04
Effects of chronic ethanol treatment of mitochondrial functions damage to coupling site I. Arch Biochem Biophys (1974) 1.03
Increased carbon tetrachloride hepatotoxicity, and its mechanism, after chronic ethanol consumption. Gastroenterology (1974) 1.03
Role of xanthine oxidase in ethanol-induced lipid peroxidation in rats. Gastroenterology (1990) 1.03
Effect of chronic ethanol ingestion on fatty acid oxidation by hepatic mitochondria. J Biol Chem (1975) 1.03
Effect of concentration of ingested ethanol on blood alcohol levels. Alcohol Clin Exp Res (1991) 1.03
Efcts of chronic ethanol feeding on serum lipoprotein metabolism in the rat. J Clin Invest (1970) 1.02