Published in Neurology on July 01, 1970
El Escorial revisited: revised criteria for the diagnosis of amyotrophic lateral sclerosis. Amyotroph Lateral Scler Other Motor Neuron Disord (2000) 15.38
Randomised trial of oral and intravenous methylprednisolone in acute relapses of multiple sclerosis. Lancet (1997) 4.43
Sphincter denervation in anorectal incontinence and rectal prolapse. Gut (1977) 3.66
Extracellular polysaccharides from suspension-cultured sycamore cells. Can J Biochem (1969) 3.63
Increased motor unit fibre density in the external anal sphincter muscle in ano-rectal incontinence: a single fibre EMG study. J Neurol Neurosurg Psychiatry (1980) 3.36
Injury to innervation of pelvic floor sphincter musculature in childbirth. Lancet (1984) 3.27
Phase II/III randomized trial of TCH346 in patients with ALS. Neurology (2007) 3.22
The pelvic floor musculature in the descending perineum syndrome. Br J Surg (1982) 3.06
Physiological studies of the anal sphincter musculature in faecal incontinence and rectal prolapse. Br J Surg (1981) 3.00
Pathogenesis of ano-rectal incontinence. A histometric study of the anal sphincter musculature. J Neurol Sci (1979) 2.87
Slowed conduction in the pudendal nerves in idiopathic (neurogenic) faecal incontinence. Br J Surg (1984) 2.73
Effect of vaginal delivery on the pelvic floor: a 5-year follow-up. Br J Surg (1990) 2.36
Assessment of pelvic-floor disorders and incontinence by electrophysiological recording of the anal reflex. Lancet (1978) 2.09
Progressive encephalomyelitis with rigidity. Brain (1976) 2.09
Electrophysiological study of motor nerve supply of pelvic floor. Lancet (1981) 2.08
Hypertrophic Pulmonary Osteo-arthropathy as First Symptom of Neoplasm. Br Med J (1937) 1.93
Perineal nerve damage in genuine stress urinary incontinence. An electrophysiological study. Br J Urol (1985) 1.88
Quality of life in multiple sclerosis in France, Germany, and the United Kingdom. Cost of Multiple Sclerosis Study Group. J Neurol Neurosurg Psychiatry (1998) 1.84
Hippocampal and neocortical ubiquitin-immunoreactive inclusions in amyotrophic lateral sclerosis with dementia. Neurosci Lett (1992) 1.82
Mitochondrial encephalomyopathies: biochemical studies in two cases revealing defects in the respiratory chain. Brain (1982) 1.80
Ubiquitin deposits in anterior horn cells in motor neurone disease. Neurosci Lett (1988) 1.77
Ubiquitin-immunoreactive intraneuronal inclusions in amyotrophic lateral sclerosis. Morphology, distribution, and specificity. Brain (1991) 1.74
Digital subtraction angiography (DSA) of the extracranial cerebral vessels: a direct comparison between intravenous and intra-arterial DSA. Clin Radiol (1991) 1.74
Trials in man with live recombinants made from A/PR/8/34 (H0 N1) and wild H3 N2 influenza viruses. Lancet (1975) 1.74
Autosomal recessive congenital intrauterine infection-like syndrome of microcephaly, intracranial calcification, and CNS disease. Am J Med Genet (1994) 1.72
Motor conduction velocity in the human spinal cord: slowed conduction in multiple sclerosis and radiation myelopathy. J Neurol Neurosurg Psychiatry (1985) 1.70
The pathology of the human muscle spindle: effect of denervation. J Neurol Sci (1974) 1.68
Longitudinal sliding of the median nerve during movements of the upper limb. J Neurol Neurosurg Psychiatry (1976) 1.65
Damage to the innervation of the voluntary anal and periurethral sphincter musculature in incontinence: an electrophysiological study. J Neurol Neurosurg Psychiatry (1984) 1.62
Unifying concept of pelvic floor disorders and incontinence. J R Soc Med (1985) 1.60
Astrovirus infection in volunteers. J Med Virol (1979) 1.58
The syndrome of transient global amnesia. Brain (1973) 1.56
Normal proximal and delayed distal conduction in the pudendal nerves of patients with idiopathic (neurogenic) faecal incontinence. J Neurol Neurosurg Psychiatry (1984) 1.55
Changes in motor unit synchronization following central nervous lesions in man. J Physiol (1993) 1.54
Treatment of acute exacerbations of multiple sclerosis with intravenous methyl-prednisolone. J Neurol Neurosurg Psychiatry (1982) 1.53
Evidence of pudendal neuropathy in patients with perineal descent and chronic straining at stool. Gut (1984) 1.52
Tyramine activates the EEG in epileptic patients. Nature (1975) 1.51
Position sense in a damaged knee. J Neurol Neurosurg Psychiatry (1986) 1.48
Electroencephalographic criteria of hypocalcemia and hypercalcemia. Arch Neurol (1972) 1.47
Risk factors in childbirth causing damage to the pelvic floor innervation. Int J Colorectal Dis (1986) 1.47
Tuberculosis of the central nervous system. Q J Med (1984) 1.46
Small deep cerebral infarcts associated with occlusive internal carotid artery disease. A hemodynamic phenomenon? Arch Neurol (1990) 1.46
Faecal incontinence in myotonic dystrophy. J Neurol Neurosurg Psychiatry (1998) 1.45
Virulence for man of a human influenza-A virus antigenically similar to "classical" swine viruses. Lancet (1976) 1.43
Myopathy due to epsilon amino-caproic acid. Muscle Nerve (1980) 1.42
John Hughlings-Jackson: a sesquicentennial tribute. J Neurol Neurosurg Psychiatry (1986) 1.41
Anorectal incontinence and rectal prolapse: differential assessment of the innervation to puborectalis and external anal sphincter muscles. Gut (1985) 1.39
Myopathy of internal anal sphincter with polyglucosan inclusions. J Pathol (1990) 1.39
Acute viral encephalitis: its diagnosis and outcome. Brain (1981) 1.39
Seizure induction by alcohol in patients with epilepsy experience in two hospital clinics. J R Soc Med (1990) 1.36
The anal reflex in idiopathic faecal incontinence: an electrophysiological study. Br J Surg (1980) 1.36
Idiopathic orthostatic hypotension. Arch Neurol (1971) 1.35
Effect of tyramine in migraine: a double-blind study. J Neurol Neurosurg Psychiatry (1972) 1.35
Central motor conduction is abnormal in motor neuron disease. J Neurol Neurosurg Psychiatry (1987) 1.35
Post-encephalitic Parkinsonism: current experience. J Neurol Neurosurg Psychiatry (1981) 1.34
Anorectal physiology validated: a repeatability study of the motor and sensory tests of anorectal function. Br J Surg (1989) 1.33
Is paradoxical contraction of puborectalis muscle of functional importance? Dis Colon Rectum (1987) 1.33
Slowed motor conduction in lumbosacral nerve roots in cauda equina lesions: a new diagnostic technique. J Neurol Neurosurg Psychiatry (1986) 1.33
Defecation 1: Testing a hypothesis for pelvic striated muscle action to open the anorectum. Tech Coloproctol (2012) 1.32
Defecation 2: Internal anorectal resistance is a critical factor in defecatory disorders. Tech Coloproctol (2012) 1.32
Myopathy in Whipple's disease. Gut (1977) 1.31
Central motor conduction in multiple sclerosis: evaluation of abnormalities revealed by transcutaneous magnetic stimulation of the brain. J Neurol Neurosurg Psychiatry (1988) 1.31
Investigation of disorders of the anorectum and colon. Ann R Coll Surg Engl (1985) 1.30
Treatment of involuntary movement disorders with tetrabenazine. J Neurol Neurosurg Psychiatry (1972) 1.30
Observations on the relation of migraine and epilepsy. An electroencephalographic, psychological and clinical study using oral tyramine. Epilepsia (1972) 1.30
Denervation of the anal sphincter causing idiopathic anorectal incontinence. J R Coll Surg Edinb (1979) 1.30
Faecal incontinence due to external anal sphincter division in childbirth is associated with damage to the innervation of the pelvic floor musculature: a double pathology. Br J Obstet Gynaecol (1985) 1.29
Relative efficacy of intravenous methylprednisolone and ACTH in the treatment of acute relapse in MS. Neurology (1989) 1.29
Longitudinal fibre splitting in neurogenic muscular disorders--its relation to the pathogenesis of "myopathic" change. Brain (1976) 1.26
Neural control of internal anal sphincter function. Br J Surg (1987) 1.26
The pattern of involvement of adult-onset acid maltase deficiency at autopsy. Muscle Nerve (1987) 1.25
Chronic perianal pain: an unsolved problem. J R Soc Med (1982) 1.24
Consensus guidelines for the design and implementation of clinical trials in ALS. World Federation of Neurology committee on Research. J Neurol Sci (1999) 1.22
Sarcoidosis presenting with stroke. Stroke (1989) 1.20
Morbidity and mortality in motor neuron disease: comparison with multiple sclerosis and Parkinson's disease: age and sex specific rates and cohort analyses. J Neurol Neurosurg Psychiatry (1985) 1.19
Evidence for the validity and reliability of the ALS assessment questionnaire: the ALSAQ-40. Amyotroph Lateral Scler Other Motor Neuron Disord (1999) 1.19
Abnormalities of the innervation of the urethral striated sphincter musculature in incontinence. Br J Urol (1984) 1.18
Implications of longitudinal muscle fibre splitting in neurogenic and myopathic disorders. J Neurol Neurosurg Psychiatry (1977) 1.17
Electrophysiological and manometric assessment of the pelvic floor in the solitary rectal ulcer syndrome. Br J Surg (1985) 1.17
Abnormalities in central and peripheral nerve conduction in patients with anorectal incontinence. J R Soc Med (1985) 1.17
Scapuloperoneal atrophy with sensory involvement: Davidenkow's syndrome. J Neurol Neurosurg Psychiatry (1975) 1.17
Predicting experimental colds in volunteers from different measures of recent life stress. J Psychosom Res (1980) 1.16
Damage to the innervation of the pelvic floor musculature in chronic constipation. Gastroenterology (1985) 1.16
Alcoholic ketoacidosis. JAMA (1971) 1.15
Hand wasting in spondylotic high cord compression: an electromyographic study. Ann Neurol (1981) 1.14
Differential diagnosis of motoneurone disease from other neurological conditions. Lancet (1986) 1.14
Focal loss of anterior horn cells in the cervical cord in motor neuron disease. Brain (1986) 1.13
The morphology and innervation of the muscle spindle in dystrophia myotonica. Brain (1972) 1.12
Carpal tunnel syndrome: which finger should be tested? An analysis of sensory conduction in digital branches of the median nerve. Muscle Nerve (1990) 1.12
Variant Alzheimer's disease with spastic paraparesis and cotton wool plaques is caused by PS-1 mutations that lead to exceptionally high amyloid-beta concentrations. Ann Neurol (2000) 1.12
Differential diagnosis of transient amnesia. Br Med J (1973) 1.12
Effects of aging on the anorectal sphincters and their innervation. Dis Colon Rectum (1989) 1.11
Lymphotoxic activity in multiple sclerosis serum. Neurology (1971) 1.11
Cytoskeletal abnormalities in motor neuron disease. An immunocytochemical study. Brain (1989) 1.10
Minicore myopathy with ophthalmoplegia caused by mutations in the ryanodine receptor type 1 gene. Neurology (2005) 1.10
A neurogenic factor in faecal incontinence in the elderly. Age Ageing (1982) 1.09
Constipation and paradoxical puborectalis contraction in anismus and Parkinson's disease: a dystonic phenomenon? J Neurol Neurosurg Psychiatry (1988) 1.09
Pattern of involvement in the cervical segments in the early stage of motor neurone disease: a single fibre EMG study. Acta Neurol Scand (1982) 1.09
Effect of chocolate in migraine: a double-blind study. J Neurol Neurosurg Psychiatry (1974) 1.08
Hereditary internal anal sphincter myopathy causing proctalgia fugax and constipation. A newly identified condition. Gastroenterology (1991) 1.08