Published in Biochem Genet on June 01, 1970
Review and hypotheses: somatic mosaicism: observations related to clinical genetics. Am J Hum Genet (1988) 3.05
The occurrence of new mutants in the X-linked recessive Lesch-Nyhan disease. Am J Hum Genet (1976) 2.51
Studies of skin fibroblasts from 10 families with HGPRT deficiency, with reference in X-chromosomal inactivation. Am J Hum Genet (1971) 1.29
Hypoxanthine-guanine phosphoribosyltransferase deficiency: chemical agents selective for mutant or normal cultured fibroblasts in mixed and heterozygote cultures. Proc Natl Acad Sci U S A (1971) 1.15
Disparate enzyme activity in erythocytes and leukocytes. A variant of hypoxanthine phosphoribosyl-transferase deficiency with an unstable enzyme. J Clin Invest (1973) 0.99
Linkage relationships of X-linked enzymes glucose-6-phosphate dehydrogenase and hypoxanthine guanine phosphoribosyltransferase: recombination in female offspring of compound heterozygotes. Am J Hum Genet (1974) 0.93
Human hypoxanthine-guanine phosphoribosyltransferase. Detection of a mutant allele by restriction endonuclease analysis. J Clin Invest (1983) 0.88
Fragile X syndrome: search for phenotypic manifestations at loci for hypoxanthine phosphoribosyltransferase and glucose-6-phosphate dehydrogenase. Am J Hum Genet (1981) 0.82
Methylation of the hypoxanthine phosphoribosyltransferase locus on the human X chromosome: implications for X-chromosome inactivation. Proc Natl Acad Sci U S A (1984) 3.53
DNA restriction endonuclease analysis for localization of human beta- and delta-globin genes on chromosome 11. Proc Natl Acad Sci U S A (1979) 3.02
Adrenoleukodystrophy: evidence for X linkage, inactivation, and selection favoring the mutant allele in heterozygous cells. Proc Natl Acad Sci U S A (1981) 2.83
X-linked hypoxanthine-guanine phosphoribosyl transferase deficiency: heterozygote has two clonal populations. Science (1968) 2.69
The occurrence of new mutants in the X-linked recessive Lesch-Nyhan disease. Am J Hum Genet (1976) 2.51
Localization of loci for hypoxanthine phosphoribosyltransferase and glucose-6-phosphate dehydrogenase and biochemical evidence of nonrandom X chromosome expression from studies of a human X-autosome translocation. Proc Natl Acad Sci U S A (1980) 2.48
Studies of X chromosome DNA methylation in normal human cells. Nature (1982) 2.34
Locus on human X chromosome for dihydrotestosterone receptor and androgen insensitivity. Proc Natl Acad Sci U S A (1975) 2.30
D-valine as a selective agent for normal human and rodent epithelial cells in culture. Cell (1975) 2.05
Three related centromere proteins are absent from the inactive centromere of a stable isodicentric chromosome. Chromosoma (1985) 2.04
Clusters of CpG dinucleotides implicated by nuclease hypersensitivity as control elements of housekeeping genes. Nature (1985) 1.96
Human-mouse somatic cell hybrids with single human chromosome (group E): link with thymidine kinase activity. Science (1968) 1.96
Isolation and characterization of cloned DNA sequences that hybridize to the human X chromosome. Cell (1980) 1.96
Characterization of a cloned DNA sequence that is present at centromeres of all human autosomes and the X chromosome and shows polymorphic variation. Proc Natl Acad Sci U S A (1984) 1.86
Differential expression of steroid sulphatase locus on active and inactive human X chromosome. Nature (1982) 1.75
Derepression with decreased expression of the G6PD locus on the inactive X chromosome in normal human cells. Cell (1982) 1.62
Genetic inactivation of the alpha-galactosidase locus in carriers of Fabry's disease. Science (1970) 1.61
Sex difference in methylation of single-copy genes in human meiotic germ cells: implications for X chromosome inactivation, parental imprinting, and origin of CpG mutations. Somat Cell Mol Genet (1990) 1.58
Mechanism of origin of complete hydatidiform moles. Nature (1980) 1.55
Incomplete X chromosome dosage compensation in chorionic villi of human placenta. Proc Natl Acad Sci U S A (1985) 1.53
Complex chromosome rearrangements. Report of a new case and literature review. Clin Genet (1980) 1.51
Expression of the G6PD locus on the human X chromosome is associated with demethylation of three CpG islands within 100 kb of DNA. EMBO J (1988) 1.50
Studies of the locus for androgen receptor: localization on the human X chromosome and evidence for homology with the Tfm locus in the mouse. Proc Natl Acad Sci U S A (1981) 1.48
Complete concordance between glucose-6-phosphate dehydrogenase activity and hypomethylation of 3' CpG clusters: implications for X chromosome dosage compensation. Nucleic Acids Res (1984) 1.42
Human and mouse hypoxanthine-guanine phosphoribosyltransferase: dimers and tetramers. Science (1979) 1.42
Stability of X chromosomal inactivation in human somatic cells. Nature (1972) 1.38
Human thymidine kinase gene locus: assignment to chromosome 17 in a hybrid of man and mouse cells. Science (1971) 1.37
Evidence for the inactivation of an X chromosome early in the development of the human female. Am J Hum Genet (1975) 1.32
Short arm deletions in group E and chromosomal "deletion" syndromes. J Pediatr (1966) 1.31
Haptoglobin: a locus on the D1 chromosome? Am J Hum Genet (1967) 1.30
Studies of skin fibroblasts from 10 families with HGPRT deficiency, with reference in X-chromosomal inactivation. Am J Hum Genet (1971) 1.29
Genetic complementation after fusion of Tay-Sachs and Sandhoff cells. Nature (1974) 1.22
DNA methylation stabilizes X chromosome inactivation in eutherians but not in marsupials: evidence for multistep maintenance of mammalian X dosage compensation. Proc Natl Acad Sci U S A (1987) 1.22
Isolation and analysis of somatic hybrids derived from two human diploid cells. Proc Natl Acad Sci U S A (1974) 1.18
Asynchronous replication of homologous loci on human active and inactive X chromosomes. Proc Natl Acad Sci U S A (1990) 1.17
The Hunter syndrome in females: is there an autosomal recessive form of iduronate sulfatase deficiency? Am J Hum Genet (1977) 1.17
The Barr body is a looped X chromosome formed by telomere association. Proc Natl Acad Sci U S A (1991) 1.15
Effect of intercellular communication on the selection of intraspecific human hybrids in HAT and ouabain. Somatic Cell Genet (1978) 1.15
Interferon production and action in mouse, hamster and somatic hybrid mouse-hamster cells. Science (1968) 1.13
Comparison of factor IX methylation on human active and inactive X chromosomes: implications for X inactivation and transcription of tissue-specific genes. EMBO J (1986) 1.13
Assignment of the haemophilia B (factor IX) locus to the q26-qter region of the X chromosome. Ann Hum Genet (1984) 1.10
Signal sequence and DNA-mediated expression of human lysosomal alpha-galactosidase A. Eur J Biochem (1987) 1.09
X-linked Hunter syndrome: the heterozygous phenotype in cell culture. Am J Hum Genet (1977) 1.07
Stability of the "two active X" phenotype in triploid somatic cells. Cell (1979) 1.07
Quantitation of contact-feeding between somatic cells in culture. Exp Cell Res (1975) 1.07
The human NTT gene: identification of a novel 17-kb noncoding nuclear RNA expressed in activated CD4+ T cells. Genomics (1997) 1.06
In search of non-random X inactivation: studies of fetal membranes heterozygous for glucose-6-phosphate dehydrogenase. Am J Hum Genet (1979) 1.06
The nature of thymidine kinase in the human-mouse hybrid cell. Biochem Genet (1969) 1.05
Stability of X chromosomal inactivation in human somatic cells transformed by SV-40. Humangenetik (1975) 1.04
Complete reactivation of X chromosomes from human chorionic villi with a switch to early DNA replication. Proc Natl Acad Sci U S A (1986) 1.03
Implications for X-chromosome regulation from studies of human X-chromosome DNA. Cold Spring Harb Symp Quant Biol (1983) 1.02
Centromeric inactivation in a dicentric human Y;21 translocation chromosome. Chromosoma (1997) 1.01
Selection and cell communication as determinants of female phenotype. Basic Life Sci (1978) 0.99
Characterization of reiterated human DNA with respect to mammalian X chromosome homology. Somat Cell Mol Genet (1984) 0.99
Localization of glucose-6-phosphate dehydrogenase in mouse and man by in situ hybridization: evidence for a single locus and transposition of homologous X-linked genes. Cytogenet Cell Genet (1985) 0.94
Non-random loss of human markers from man-mouse somatic cell hybrids. Nature (1974) 0.93
Studies of human-mouse cell hybrids with respect to X-chromosome inactivation. Basic Life Sci (1978) 0.89
DNA methylation of the fragile X locus in somatic and germ cells during fetal development: relevance to the fragile X syndrome and X inactivation. Somat Cell Mol Genet (1993) 0.89
Comparison of contact-mediated communication in normal and transformed human cells in culture. Proc Natl Acad Sci U S A (1977) 0.89
Genetic disorders of male sexual differentiation. Adv Hum Genet (1980) 0.88
Androgen receptors and metabolism in cultured human fetal fibroblasts. Pediatr Res (1980) 0.88
Gene expression in euploid human hybrid cells: ouabain resistance is codominant. Somatic Cell Genet (1978) 0.88
Hybridization of mammalian somatic cells. Prog Med Genet (1970) 0.87
Effect of ouabain resistance on human diploid fibroblasts carrying other genetic variants. Exp Cell Res (1975) 0.86
Sex differences in activity of glucose 6-phosphate dehydrogenase from cultured human fetal lung cells despite X-inactivation. Biochem Genet (1973) 0.86
Unreliability of the microcomplement fixation method for Xga typing of cultured fibroblasts. Birth Defects Orig Artic Ser (1976) 0.86
In search of nonrandom X inactivation: studies of the placenta from newborns heterozygous for glucose-6-phosphate dehydrogenase. Basic Life Sci (1978) 0.86
Contact-mediated communication of ouabain resistance in mammalian cells in culture. Nature (1977) 0.85
Translocation of the nucleolus organizer region to the human X chromosome. Am J Hum Genet (1986) 0.85
Glycogen-storage disease associated with phosphorylase kinase deficiency: evidence for X inactivation. Am J Hum Genet (1974) 0.85
DNA replication analysis of FMR1, XIST, and factor 8C loci by FISH shows nontranscribed X-linked genes replicate late. Am J Hum Genet (1994) 0.85
Hybridization of somatic cells derived from mouse and syrian hamster: evolution of karyotype and enzyme studies. Biochem Genet (1968) 0.84
The postulated X-inactivation center at Xq27 is most reasonably explained by ascertainment bias: heterozygous expression of recessive mutations is a powerful means of detecting unbalanced X inactivation. Am J Hum Genet (1993) 0.84
The prenatal diagnosis of adrenoleukodystrophy. Demonstration of increased hexacosanoic acid levels in cultured amniocytes and fetal adrenal gland. Pediatr Res (1982) 0.83
Chromatin loop structure of the human X chromosome: relevance to X inactivation and CpG clusters. Mol Cell Biol (1989) 0.83
Familial skewed X inactivation and X-linked mutations: unbalanced X inactivation is a powerful means to ascertain X-linked genes that affect cell proliferation. Am J Hum Genet (1998) 0.83
Fragile X syndrome: search for phenotypic manifestations at loci for hypoxanthine phosphoribosyltransferase and glucose-6-phosphate dehydrogenase. Am J Hum Genet (1981) 0.82
Hyperexpression of HPRT induced by 5-azacytidine in mouse-human hybrid reactivants. Am J Hum Genet (1985) 0.82
Molecular characterization of tiny ring X chromosomes from females with functional X chromosome disomy and lack of cis X inactivation. Genomics (1995) 0.81
Studies of X-chromosome inactivation in trisomies. Cytogenet Cell Genet (1989) 0.81
Evidence for a relationship between DNA methylation and DNA replication from studies of the 5-azacytidine-reactivated allocyclic X chromosome. Exp Cell Res (1985) 0.81
Familial occurrence of the somatic phenotype of Turner's syndrome. Johns Hopkins Med J (1967) 0.81
Second trimester prenatal diagnosis of epignathus teratoma in ring X chromosome mosaicism with inactive ring X chromosome. Ann Genet (2001) 0.80
Thyroxin, satellite association and trisomy. Nature (1966) 0.80
Evidence for two active X chromosomes in germ cells of female before meiotic entry. Nature (1977) 0.80
XIST expression is repressed when X inactivation is reversed in human placental cells: a model for study of XIST regulation. Somat Cell Mol Genet (1995) 0.80
Enrichment of human heterokaryons by Ficoll gradient for complementation analysis of iduronate sulfatase deficiency. Somatic Cell Genet (1979) 0.79
Glucose-6-phosphate dehydrogenase as a probe for the study of X-chromosome inactivation in hunan females. Isozymes Curr Top Biol Med Res (1983) 0.78
The XIST locus replicates late on the active X, and earlier on the inactive X based on FISH DNA replication analysis of somatic cell hybrids. Somat Cell Mol Genet (1995) 0.78
Renal enzymes in kidney cells selected by D-valine medium. J Cell Physiol (1977) 0.78
Reactivation of X-linked genes in human fibroblasts transformed by origin-defective SV40. Somat Cell Mol Genet (1986) 0.78
Some insights into X chromosome inactivation from studies of human cells. Ann Endocrinol (Paris) (1981) 0.77
Methylation status of genes flanking the fragile site in males with the fragile-X syndrome: a test of the imprinting hypothesis. Am J Hum Genet (1990) 0.77
Molecular studies of marsupial X chromosomes reveal limited sequence homology of mammalian X-linked genes. Genomics (1987) 0.76
Phenotypic heterogeneity within clones of fetal human cells. Am J Hum Genet (1981) 0.75
Selection of epithelial cells in culture by D-valine medium. Birth Defects Orig Artic Ser (1980) 0.75
Somatic cell hybrids: applications relevant to genetic disease. J Pediatr (1971) 0.75
Unreliability of the microcomplement fixation method for Xga typing of cultured fibroblasts. Cytogenet Cell Genet (1976) 0.75
Biochemical and genetic aspects of mental retardation. Annu Rev Med (1966) 0.75