PubRank

U L RajBhandary

Author PubWeight™ 198.51‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Use of in vitro 32P labeling in the sequence analysis of nonradioactive tRNAs. Methods Enzymol 1979 9.54
2 Transfer RNA: molecular structure, sequence, and properties. Annu Rev Biochem 1976 7.41
3 Sequence analysis of 5'[32P] labeled mRNA and tRNA using polyacrylamide gel electrophoresis. Nucleic Acids Res 1978 6.25
4 Direct analysis of aminoacylation levels of tRNAs in vivo. Application to studying recognition of Escherichia coli initiator tRNA mutants by glutaminyl-tRNA synthetase. J Biol Chem 1991 5.02
5 The use of nuclease P1 in sequence analysis of end group labeled RNA. Nucleic Acids Res 1977 4.67
6 Novel features in the genetic code and codon reading patterns in Neurospora crassa mitochondria based on sequences of six mitochondrial tRNAs. Proc Natl Acad Sci U S A 1980 3.19
7 Formylatable methionine transfer RNA from Mycoplasma: purification and comparison of partial nucleotide sequences with those of other prokaryotic initiator tRNAs. Nucleic Acids Res 1975 2.89
8 Studies on polynucleotides. LXXXII. Yeast phenylalanine transfer ribonucleic acid: partial digestion with ribonuclease T-1 and derivation of the total primary structure. J Biol Chem 1968 2.79
9 A transposable element from Halobacterium halobium which inactivates the bacteriorhodopsin gene. Proc Natl Acad Sci U S A 1982 2.76
10 High-frequency spontaneous mutation in the bacterio-opsin gene in Halobacterium halobium is mediated by transposable elements. Proc Natl Acad Sci U S A 1983 2.70
11 The nucleotide sequence of formylmethionine tRNA from Mycoplasma mycoides sp. capri. Nucleic Acids Res 1978 2.69
12 Nucleotide sequence of salmon testes and salmon liver cytoplasmic initiator tRNA. Cell 1975 2.46
13 The primary structure of yeast initiator transfer ribonucleic acid. Biochem Biophys Res Commun 1972 2.25
14 Escherichia coli formylmethionine tRNA: mutations in GGGCCC sequence conserved in anticodon stem of initiator tRNAs affect initiation of protein synthesis and conformation of anticodon loop. Proc Natl Acad Sci U S A 1987 2.21
15 Dispersed 5S RNA genes in N. crassa: structure, expression and evolution. Cell 1981 2.21
16 Studies on polynucleotides. XCI. Yeast methionine transfer ribonucleic acid: purification, properties, and terminal nucleotide sequences. J Biol Chem 1969 2.18
17 The first nucleotide sequence of an organelle transfer RNA: chloroplastic tRNAphe. Cell 1976 2.13
18 Secondary structure of mouse and rabbit alpha- and beta-globin mRNAs: differential accessibility of alpha and beta initiator AUG codons towards nucleases. Cell 1980 2.09
19 Site-specific mutagenesis on cloned DNAs: generation of a mutant of Escherichia coli tyrosine suppressor tRNA in which the sequence G-T-T-C corresponding to the universal G-T-pseudouracil-C sequence of tRNAs is changed to G-A-T-C. Proc Natl Acad Sci U S A 1981 2.09
20 An inducible mammalian amber suppressor: propagation of a poliovirus mutant. Cell 1987 2.08
21 Nucleotide sequence of rabbit liver and sheep mammary gland cytoplasmic initiatory transfer RNAs. Nature 1974 2.03
22 Nucleotide sequence of 5' terminus of alfalfa mosaic virus RNA 4 leading into coat protein cistron. Proc Natl Acad Sci U S A 1977 1.99
23 Intron within the large rRNA gene of N. crassa mitochondria: a long open reading frame and a consensus sequence possibly important in splicing. Cell 1982 1.96
24 Characterization of tRNA precursor splicing in mammalian extracts. J Biol Chem 1983 1.93
25 Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 1. General introduction. J Biol Chem 1976 1.91
26 Studies on polynucleotides. 103. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. J Mol Biol 1972 1.90
27 An amber suppressor tRNA gene derived by site-specific mutagenesis: cloning and function in mammalian cells. Proc Natl Acad Sci U S A 1982 1.86
28 Establishment of mammalian cell lines containing multiple nonsense mutations and functional suppressor tRNA genes. Cell 1982 1.76
29 Structure and function of initiator methionine tRNA from the mitochondria of Neurospora crassa. Cell 1978 1.74
30 Amber, ochre and opal suppressor tRNA genes derived from a human serine tRNA gene. EMBO J 1985 1.68
31 Site-directed isotope labelling and FTIR spectroscopy of bacteriorhodopsin. Nat Struct Biol 1994 1.67
32 Structural and sequence elements important for recognition of Escherichia coli formylmethionine tRNA by methionyl-tRNA transformylase are clustered in the acceptor stem. J Biol Chem 1991 1.66
33 Expression of a X. laevis tRNATyr gene in mammalian cells. Nucleic Acids Res 1982 1.66
34 Organization of tRNA and rRNA genes in N. crassa mitochondria: intervening sequence in the large rRNA gene and strand distribution of the RNA genes. Cell 1979 1.65
35 Studies on polynucleotides. CI. Escherichia coli tyrosine and formylmethionine transfer ribonucleic acids: effect of chemical modification of 4-thiouridine to uridine on their biological properties. J Biol Chem 1972 1.64
36 Initiation of protein synthesis from a termination codon. Proc Natl Acad Sci U S A 1990 1.64
37 Nucleotide sequence studies on yeast phenylalanine sRNA. Cold Spring Harb Symp Quant Biol 1966 1.61
38 Introduction of UAG, UAA, and UGA nonsense mutations at a specific site in the Escherichia coli chloramphenicol acetyltransferase gene: use in measurement of amber, ochre, and opal suppression in mammalian cells. Mol Cell Biol 1986 1.60
39 2-Methylthio N6-(delta 2-isopentenyl) adenosine: a component of E. coli tyrosine transfer RNA. Biochem Biophys Res Commun 1968 1.59
40 Studies on polynucleotides. LXXXVI. Enzymic hydrolysis of N-acylaminoacyl-transfer RNA. J Mol Biol 1968 1.57
41 Studies on polynucleotides. LXXVII. The labeling of end groups in polynucleotide chains: the selective modification of diol end groups in ribonucleic acids. J Biol Chem 1968 1.55
42 Mutants of Escherichia coli formylmethionine tRNA: a single base change enables initiator tRNA to act as an elongator in vitro. Proc Natl Acad Sci U S A 1987 1.52
43 Interesting and unusual features in the sequence of Neurospora crassa mitochondrial tyrosine transfer RNA. Proc Natl Acad Sci U S A 1979 1.51
44 Bacteriorhodopsin: partial sequence of mRNA provides amino acid sequence in the precursor region. Proc Natl Acad Sci U S A 1981 1.48
45 Mutants of initiator tRNA that function both as initiators and elongators. J Biol Chem 1991 1.44
46 Studies on polynucleotides. LXXIX. Yeast phenylalanine transfer ribonucleic acid: products obtained by degradation with pancreatic ribonuclease. J Biol Chem 1968 1.38
47 Expression of the bacterioopsin gene in Halobacterium halobium using a multicopy plasmid. Proc Natl Acad Sci U S A 1991 1.37
48 Striking effects of coupling mutations in the acceptor stem on recognition of tRNAs by Escherichia coli Met-tRNA synthetase and Met-tRNA transformylase. Proc Natl Acad Sci U S A 1992 1.36
49 Suppression of amber codons in vivo as evidence that mutants derived from Escherichia coli initiator tRNA can act at the step of elongation in protein synthesis. J Biol Chem 1989 1.30
50 Amber suppression in mammalian cells dependent upon expression of an Escherichia coli aminoacyl-tRNA synthetase gene. Mol Cell Biol 1996 1.29
51 Initiation of protein synthesis without formylation in a mutant of Escherichia coli that grows in the absence of tetrahydrofolate. J Bacteriol 1977 1.29
52 Nucleotide sequence of human placenta cytoplasmic initiator tRNA. Cell 1975 1.29
53 NMR analysis of tRNA acceptor stem microhelices: discriminator base change affects tRNA conformation at the 3' end. Proc Natl Acad Sci U S A 1994 1.28
54 Cytochrome oxidase subunit III gene in Neurospora crassa mitochondria. Location and sequence. J Biol Chem 1982 1.26
55 Nucleotide sequence of the 5' terminus of satellite tobacco necrosis virus ribonucleic acid. Biochemistry 1979 1.25
56 Initiation of protein synthesis in mammalian cells with codons other than AUG and amino acids other than methionine. Mol Cell Biol 1998 1.24
57 Measurement of suppressor transfer RNA activity. Science 1983 1.22
58 From elongator tRNA to initiator tRNA. Proc Natl Acad Sci U S A 1993 1.22
59 Highly conserved GC-rich palindromic DNA sequences flank tRNA genes in Neurospora crassa mitochondria. Cell 1981 1.21
60 Nucleotide sequence of wheat germ cytoplasmic initiator methionine transfer ribonucleic acid. Nucleic Acids Res 1982 1.21
61 Initiation of protein synthesis in Saccharomyces cerevisiae mitochondria without formylation of the initiator tRNA. J Bacteriol 2000 1.20
62 Twenty-first aminoacyl-tRNA synthetase-suppressor tRNA pairs for possible use in site-specific incorporation of amino acid analogues into proteins in eukaryotes and in eubacteria. Proc Natl Acad Sci U S A 2001 1.20
63 Cytochrome b gene of Neurospora crassa mitochondria. Partial sequence and location of introns at sites different from those in Saccharomyces cerevisiae and Aspergillus nidulans. J Biol Chem 1984 1.17
64 The discriminator base influences tRNA structure at the end of the acceptor stem and possibly its interaction with proteins. Proc Natl Acad Sci U S A 1993 1.14
65 Effect of the amino acid attached to Escherichia coli initiator tRNA on its affinity for the initiation factor IF2 and on the IF2 dependence of its binding to the ribosome. J Biol Chem 1997 1.14
66 Use of short synthetic DNA duplexes as substrates for the restriction endonucleases Hpa II and Mno I. J Biol Chem 1979 1.14
67 The role of nucleotides conserved in eukaryotic initiator methionine tRNAs in initiation of protein synthesis. J Biol Chem 1993 1.12
68 Escherichia coli B lacks one of the two initiator tRNA species present in E. coli K-12. J Bacteriol 1992 1.12
69 Single crystals of transfer RNA from formylmethionine and phenylalanine transfer RNA's. Science 1968 1.11
70 Import of amber and ochre suppressor tRNAs into mammalian cells: a general approach to site-specific insertion of amino acid analogues into proteins. Proc Natl Acad Sci U S A 2001 1.11
71 Synthesis of an ochre suppressor tRNA gene and expression in mammalian cells. EMBO J 1984 1.11
72 Nucleotide sequence of a high copy number plasmid from Halobacterium strain GRB. Nucleic Acids Res 1990 1.10
73 Mutants of Escherichia coli initiator tRNA that suppress amber codons in Saccharomyces cerevisiae and are aminoacylated with tyrosine by yeast extracts. Proc Natl Acad Sci U S A 1991 1.09
74 Nucleotide sequence of Neurospora crassa cytoplasmic initiator tRNA. Nucleic Acids Res 1977 1.08
75 Studies on polynucleotides. LXXX. Yeast phenylalanine transfer ribonucleic acid: products obtained by degradation with ribonuclease T1. J Biol Chem 1968 1.08
76 Expression in vivo of a mutant human initiator tRNA gene in mammalian cells using a simian virus 40 vector. J Biol Chem 1985 1.07
77 Role of methionine and formylation of initiator tRNA in initiation of protein synthesis in Escherichia coli. J Bacteriol 1992 1.06
78 The A1 x U72 base pair conserved in eukaryotic initiator tRNAs is important specifically for binding to the eukaryotic translation initiation factor eIF2. Mol Cell Biol 1996 1.06
79 The nucleotide sequence of the initiator tRNA from Drosophila melanogaster. Nucleic Acids Res 1979 1.06
80 The recognition by RNase P of precursor tRNAs. J Biol Chem 1988 1.05
81 Nuclear genes for cytochrome c oxidase subunits of Neurospora crassa. Isolation and characterization of cDNA clones for subunits IV, V, VI, and possibly VII. J Biol Chem 1986 1.05
82 Construction, stable transformation, and function of an amber suppressor tRNA gene in Drosophila melanogaster. Proc Natl Acad Sci U S A 1989 1.04
83 Initiator tRNA and its role in initiation of protein synthesis. Cold Spring Harb Symp Quant Biol 2001 1.03
84 Site-specific mutagenesis on a human initiator methionine tRNA gene within a sequence conserved in all eukaryotic initiator tRNAs and studies of its effects on in vitro transcription. J Biol Chem 1985 1.02
85 Attempted expression of a human initiator tRNA gene in Saccharomyces cerevisiae. J Biol Chem 1985 1.01
86 Mutants of Escherichia coli initiator tRNA defective in initiation. Effects of overproduction of methionyl-tRNA transformylase and the initiation factors IF2 and IF3. J Biol Chem 1995 1.01
87 A single mutation in loop IV of Escherichia coli SuIII tRNA blocks processing at both 5'- and 3'-ends of the precursor tRNA. J Biol Chem 1986 1.00
88 Mapping and cloning of Neurospora crassa mitochondrial transfer RNA genes. J Biol Chem 1979 0.98
89 Transcripts and processing patterns for the ribosomal RNA and transfer RNA region of Neurospora crassa mitochondrial DNA. J Biol Chem 1981 0.97
90 Suppressor mutations in Escherichia coli methionyl-tRNA formyltransferase: role of a 16-amino acid insertion module in initiator tRNA recognition. Proc Natl Acad Sci U S A 1997 0.97
91 Developmental regulation of the gene for formate dehydrogenase in Neurospora crassa. J Bacteriol 1993 0.96
92 The nucleotide sequence of Euglena cytoplasmic phenylalanine transfer RNA. Evidence for possible classifications of Euglena among the animal rather than the plant kingdom. Nucleic Acids Res 1981 0.96
93 The E35 stopper mutant of Neurospora crassa: precise localization of deletion endpoints in mitochondrial DNA and evidence that the deleted DNA codes for a subunit of NADH dehydrogenase. EMBO J 1986 0.96
94 Mycobacterium tuberculosis Rv2118c codes for a single-component homotetrameric m1A58 tRNA methyltransferase. Nucleic Acids Res 2004 0.96
95 A formylatable methionine transfer ribonucleic acid from yeast: comparison of coding properties and sequences around the anticodon with Escherichia coli formylatable methionine transfer RNA. J Mol Biol 1970 0.95
96 Lysine 207 as the site of cross-linking between the 3'-end of Escherichia coli initiator tRNA and methionyl-tRNA formyltransferase. J Biol Chem 1997 0.95
97 Functional interaction of an arginine conserved in the sixteen amino acid insertion module of Escherichia coli methionyl-tRNA formyltransferase with determinants for formylation in the initiator tRNA. Biochemistry 1998 0.93
98 Important role of the amino acid attached to tRNA in formylation and in initiation of protein synthesis in Escherichia coli. J Biol Chem 1996 0.92
99 Studies on polynucleotides. LXXVI. Specificity of transfer RNA for codon recognition as studied by amino acid incorporation. J Mol Biol 1967 0.92
100 An anticodon sequence mutant of Escherichia coli initiator tRNA: possible importance of a newly acquired base modification next to the anticodon on its activity in initiation. J Bacteriol 1995 0.91
101 Ribosome-initiator tRNA complex as an intermediate in translation initiation in Escherichia coli revealed by use of mutant initiator tRNAs and specialized ribosomes. EMBO J 1996 0.91
102 RNA processing in Neurospora crassa mitochondria: use of transfer RNA sequences as signals. EMBO J 1985 0.90
103 CXV. Total synthesis of the structural gene for an alanine transfer RNA from yeast. Enzymic joining to form the total DNA duplex. J Mol Biol 1972 0.90
104 Saccharomyces cerevisiae cytoplasmic tyrosyl-tRNA synthetase gene. Isolation by complementation of a mutant Escherichia coli suppressor tRNA defective in aminoacylation and sequence analysis. J Biol Chem 1993 0.90
105 Importance of the anticodon sequence in the aminoacylation of tRNAs by methionyl-tRNA synthetase and by valyl-tRNA synthetase in an Archaebacterium. J Biol Chem 2000 0.90
106 Nucleotide sequence of ISH11, a new Halobacterium halobium insertion element isolated from the plasmid pGRB1. Nucleic Acids Res 1990 0.90
107 Cytoplasmic leucyl-tRNA synthetase of Neurospora crassa is not specified by the leu-5 locus. Genetics 1988 0.90
108 Functional suppression in mammalian cells of nonsense mutations in the herpes simplex virus thymidine kinase gene by suppressor tRNA genes. J Virol 1983 0.90
109 Cytochrome oxidase subunit V gene of Neurospora crassa: DNA sequences, chromosomal mapping, and evidence that the cya-4 locus specifies the structural gene for subunit V. Mol Cell Biol 1989 0.89
110 Studies on polynucleotides. LXXXI. Yeast phenylalanine transfer ribonucleic acid: partial digestion with pancreatic ribonuclease. J Biol Chem 1968 0.89
111 Missense suppression in tryptophan synthetase. Cold Spring Harb Symp Quant Biol 1966 0.88
112 Studies on polynucleotides. 78. Yeast phenylalanine transfer ribonucleic acid: terminal sequences. J Biol Chem 1968 0.87
113 Tetracycline-regulated suppression of amber codons in mammalian cells. Mol Cell Biol 1998 0.87
114 Structural studies on tRNA acceptor stem microhelices: exchange of the discriminator base A73 for G in human tRNALeu switches the acceptor specificity from leucine to serine possibly by decreasing the stability of the terminal G1-C72 base pair. Nucleic Acids Res 1997 0.87
115 Site-directed isotope labeling and ATR-FTIR difference spectroscopy of bacteriorhodopsin: the peptide carbonyl group of Tyr 185 is structurally active during the bR-->N transition. Biochemistry 1995 0.86
116 Paradoxical observations on the 5' terminus of ovalbumin messenger ribonucleic acid. J Biol Chem 1978 0.86
117 Chemical reactivity of E. coli 5S RNA in situ in the 50S ribosomal subunit. Nucleic Acids Res 1983 0.84
118 Escherichia coli methionyl-tRNA formyltransferase: role of amino acids conserved in the linker region and in the C-terminal domain on the specific recognition of the initiator tRNA. Biochemistry 2000 0.83
119 Site-directed isotope labeling and FTIR spectroscopy: assignment of tyrosine bands in the bR-->M difference spectrum of bacteriorhodopsin. Biophys Chem 1995 0.82
120 Escherichia coli initiator tRNA: structure-function relationships and interactions with the translational machinery. Biochem Cell Biol 1996 0.82
121 Induced fit of a peptide loop of methionyl-tRNA formyltransferase triggered by the initiator tRNA substrate. Proc Natl Acad Sci U S A 1999 0.82
122 Saccharomyces cerevisiae SUP53 tRNA gene transcripts are processed by mammalian cell extracts in vitro but are not processed in vivo. Mol Cell Biol 1988 0.81
123 Structural studies on transfer RNA: crystallization of formylmethionine and leucine transfer RNA's. Science 1969 0.81
124 The nucleotide sequence of phenylalanine tRNA from the cytoplasm of Neurospora crassa. Nucleic Acids Res 1980 0.80
125 Relationship between the structure and function of Escherichia coli initiator tRNA. Biochimie 1993 0.80
126 Nucleotide sequence at the 5' terminus of adenovirus 2 late messenger RNA. J Biol Chem 1979 0.79
127 E. coli tyrosine transfer RNA: chemical modification of thiouridine to uridine. Biochem Biophys Res Commun 1970 0.79
128 Suppressor mutations in Escherichia coli methionyl-tRNA formyltransferase that compensate for the formylation defect of a mutant tRNA aminoacylated with lysine. Biochemistry 2000 0.77
129 The nucleotide sequence of blue-green algae phenylalanine-tRNA and the evolutionary origin of chloroplasts. Nucleic Acids Res 1982 0.76
130 Genetic code. Modified bases and aminoacylation. Nature 1988 0.76
131 Structure and organization of tRNA, rRNA, and protein genes in neurospora crassa mitochondria. Princess Takamatsu Symp 1982 0.76
132 Sequence of the met-10+ locus of Neurospora crassa: homology to a sequence of unknown function in Saccharomyces cerevisiae chromosome 8. Gene 1995 0.75
133 Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 11. Enzymatic joining to form the total DNA duplex. J Biol Chem 1976 0.75