Published in J Mol Biol on December 28, 1972
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Polynucleotide kinase from a T4 mutant which lacks the 3' phosphatase activity. Nucleic Acids Res (1978) 1.27
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Cleavage map of bacteriophage phiX174 RF DNA by restriction enzymes. Nucleic Acids Res (1976) 0.83
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Construction of a double-stranded deoxyribonucleotide sequence of 45 base pairs designed to code for S-peptide 2-14 of bovine ribonuclease A. Nucleic Acids Res (1975) 0.75
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Partial characterization of an endonuclease activity which appears in nuclease free T4 polynucleotide kinase. Nucleic Acids Res (1976) 0.75
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Effect of salts and polyamines on T4 polynucleotide kinase. Biochemistry (1975) 22.01
Reversal of bacteriophage T4 induced polynucleotide kinase action. Biochemistry (1973) 21.41
Improved free-energy parameters for predictions of RNA duplex stability. Proc Natl Acad Sci U S A (1986) 19.52
Physical characterization and simultaneous purification of bacteriophage T4 induced polynucleotide kinase, polynucleotide ligase, and deoxyribonucleic acid polymerase. Biochemistry (1973) 11.45
Large-scale analysis of the yeast genome by transposon tagging and gene disruption. Nature (1999) 9.87
Use of in vitro 32P labeling in the sequence analysis of nonradioactive tRNAs. Methods Enzymol (1979) 9.54
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A two-dimensional nuclear Overhauser enhancement (2D NOE) experiment for the elucidation of complete proton-proton cross-relaxation networks in biological macromolecules. Biochem Biophys Res Commun (1980) 6.64
Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin. Science (1996) 6.50
Differential gene expression in response to mechanical wounding and insect feeding in Arabidopsis. Plant Cell (2000) 6.40
Sequence analysis of 5'[32P] labeled mRNA and tRNA using polyacrylamide gel electrophoresis. Nucleic Acids Res (1978) 6.25
High-pressure liquid chromatography in polynucleotide synthesis. Biochemistry (1978) 5.98
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Resolving the functions of overlapping viral genes by site-specific mutagenesis at a mRNA splice site. Nature (1982) 5.61
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Inhibition of RNA cleavage but not polyadenylation by a point mutation in mRNA 3' consensus sequence AAUAAA. Nature (1983) 5.18
IS431, a staphylococcal insertion sequence-like element related to IS26 from Proteus vulgaris. Gene (1987) 5.15
Expression of a synthetic bovine rhodopsin gene in monkey kidney cells. Proc Natl Acad Sci U S A (1987) 5.11
Direct analysis of aminoacylation levels of tRNAs in vivo. Application to studying recognition of Escherichia coli initiator tRNA mutants by glutaminyl-tRNA synthetase. J Biol Chem (1991) 5.02
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Gene synthesis machines: DNA chemistry and its uses. Science (1985) 4.76
The use of nuclease P1 in sequence analysis of end group labeled RNA. Nucleic Acids Res (1977) 4.67
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In situ activation of bis-dialkylaminophosphines--a new method for synthesizing deoxyoligonucleotides on polymer supports. Nucleic Acids Res (1984) 4.55
Glutamic acid-113 serves as the retinylidene Schiff base counterion in bovine rhodopsin. Proc Natl Acad Sci U S A (1989) 4.44
A collision gradient method to determine the immersion depth of nitroxides in lipid bilayers: application to spin-labeled mutants of bacteriorhodopsin. Proc Natl Acad Sci U S A (1994) 4.27
Crystal structure of rat DNA polymerase beta: evidence for a common polymerase mechanism. Science (1994) 4.11
Complete nucleotide sequence of the 16S rRNA gene of Mycobacterium bovis BCG. J Bacteriol (1988) 4.10
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Studies on polynucleotides, XLIX. Stimulation of the binding of aminoacyl-sRNA's to ribosomes by ribotrinucleotides and a survey of codon assignments for 20 amino acids. Proc Natl Acad Sci U S A (1965) 3.71
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Specific amino acid substitutions in bacterioopsin: Replacement of a restriction fragment in the structural gene by synthetic DNA fragments containing altered codons. Proc Natl Acad Sci U S A (1984) 3.67
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The bacteriorhodopsin gene. Proc Natl Acad Sci U S A (1981) 3.40
A new form of amyloid protein associated with chronic hemodialysis was identified as beta 2-microglobulin. Biochem Biophys Res Commun (1985) 3.40
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Novel features in the genetic code and codon reading patterns in Neurospora crassa mitochondria based on sequences of six mitochondrial tRNAs. Proc Natl Acad Sci U S A (1980) 3.19
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Total synthesis of a gene for bovine rhodopsin. Proc Natl Acad Sci U S A (1986) 3.08
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Enzymatic Adenylylation of Streptomycin and Spectinomycin by R-Factor-Resistant Escherichia coli. Infect Immun (1970) 3.02
Cysteine residues 110 and 187 are essential for the formation of correct structure in bovine rhodopsin. Proc Natl Acad Sci U S A (1988) 3.01
A strain-driven morphotropic phase boundary in BiFeO3. Science (2009) 2.95
The canals of Hering and hepatic stem cells in humans. Hepatology (1999) 2.93
Molecular cloning of a porcine gene syk that encodes a 72-kDa protein-tyrosine kinase showing high susceptibility to proteolysis. J Biol Chem (1991) 2.89
Formylatable methionine transfer RNA from Mycoplasma: purification and comparison of partial nucleotide sequences with those of other prokaryotic initiator tRNAs. Nucleic Acids Res (1975) 2.89
Traction therapy in sciatica due to disc prolapse (does traction treatment have any positive effect on patients suffering from sciatica caused by disc prolapse?). J Oslo City Hosp (1973) 2.89
Structure and function in rhodopsin. 7. Point mutations associated with autosomal dominant retinitis pigmentosa. Biochemistry (1994) 2.88
RNA splicing is required to make the messenger RNA for a variant surface antigen in trypanosomes. Nucleic Acids Res (1982) 2.87
Binding of synthetic lactose operator DNAs to lactose represessors. Proc Natl Acad Sci U S A (1977) 2.86
Search for a resonance decaying into WZ boson pairs in pp collisions. Phys Rev Lett (2010) 2.83
Molecular cloning, expression, and gene localization of a fourth melanocortin receptor. J Biol Chem (1993) 2.81
Substitution of amino acids Asp-85, Asp-212, and Arg-82 in bacteriorhodopsin affects the proton release phase of the pump and the pK of the Schiff base. Proc Natl Acad Sci U S A (1990) 2.80
Studies on polynucleotides. LXXXII. Yeast phenylalanine transfer ribonucleic acid: partial digestion with ribonuclease T-1 and derivation of the total primary structure. J Biol Chem (1968) 2.79
Bacterio-opsin mRNA in wild-type and bacterio-opsin-deficient Halobacterium halobium strains. Proc Natl Acad Sci U S A (1984) 2.77
A transposable element from Halobacterium halobium which inactivates the bacteriorhodopsin gene. Proc Natl Acad Sci U S A (1982) 2.76
Immediate early and early lytic cycle proteins are frequent targets of the Epstein-Barr virus-induced cytotoxic T cell response. J Exp Med (1997) 2.76
Association of B12 deficiency and clinical neuropathy with metformin use in type 2 diabetes patients. J Postgrad Med (2013) 2.75
The cost of treating community-acquired pneumonia. Clin Ther (1998) 2.73
High-frequency spontaneous mutation in the bacterio-opsin gene in Halobacterium halobium is mediated by transposable elements. Proc Natl Acad Sci U S A (1983) 2.70
Early stages of motor neuron differentiation revealed by expression of homeobox gene Islet-1. Science (1992) 2.70
The nucleotide sequence of formylmethionine tRNA from Mycoplasma mycoides sp. capri. Nucleic Acids Res (1978) 2.69
Replacement of aspartic acid-96 by asparagine in bacteriorhodopsin slows both the decay of the M intermediate and the associated proton movement. Proc Natl Acad Sci U S A (1989) 2.64
Cloning and characterization of the gene for immunogenic protein MPB64 of Mycobacterium bovis BCG. Infect Immun (1989) 2.62
Metal ion catalysis in the Tetrahymena ribozyme reaction. Nature (1993) 2.62
Actinin-4, a novel actin-bundling protein associated with cell motility and cancer invasion. J Cell Biol (1998) 2.62
Enzymatic oligomerization of bacteriophage P22 DNA and of linear Simian virus 40 DNA. Proc Natl Acad Sci U S A (1972) 2.62
[Testicular atrophy of mice induced by ethylene glycol mono alkyl ethers (author's transl)]. Sangyo Igaku (1979) 2.61
Pneumocystis carinii infection in patients of AIDS in India. J Assoc Physicians India (1993) 2.57
Chemical synthesis of a self-complementary octanucleotide, dG-G-T-T-A-A-C-C by a modified triester method. Nucleic Acids Res (1978) 2.56
A new method of diagnosing gastric intestinal metaplasia: narrow-band imaging with magnifying endoscopy. Endoscopy (2006) 2.52
Total synthesis of the gene for an alanine transfer ribonucleic acid from yeast. Nature (1970) 2.51