Published in N Engl J Med on May 20, 1971
Effect of chronic and acute cigarette smoking on the pharyngo-upper oesophageal sphincter contractile reflex and reflexive pharyngeal swallow. Gut (1998) 1.70
Cough. 3: chronic cough and gastro-oesophageal reflux. Thorax (2003) 1.70
Smoking and gastro-oesophageal reflux. Br Med J (1972) 1.69
Lifestyle Intervention in Gastroesophageal Reflux Disease. Clin Gastroenterol Hepatol (2015) 1.47
Chronic persistent cough and gastro-oesophageal reflux. Thorax (1991) 1.46
Mechanisms of acid reflux associated with cigarette smoking. Gut (1990) 1.41
Long-Term Benefits of Smoking Cessation on Gastroesophageal Reflux Disease and Health-Related Quality of Life. PLoS One (2016) 1.39
The effects of premedication drugs on the lower oesophageal high pressure zone and reflux status of rhesus monkeys and man. Gut (1975) 1.38
Cigarette smoking increases risk of Barrett's esophagus: an analysis of the Barrett's and Esophageal Adenocarcinoma Consortium. Gastroenterology (2012) 1.28
Smoking and the gastrointestinal tract. Gut (1972) 1.22
Lifestyle factors and risk for symptomatic gastroesophageal reflux in monozygotic twins. Gastroenterology (2006) 1.22
Early identification of alcohol abuse: 2: Clinical and laboratory indicators. Can Med Assoc J (1981) 1.21
Body weight, lifestyle, dietary habits and gastroesophageal reflux disease. World J Gastroenterol (2009) 1.18
Effect of cigarette smoking on the lower oesophageal sphincter. Gut (1977) 1.17
Gastroesophageal reflux: clinical presentations, diagnosis and management. CMAJ (1986) 1.15
The oesophagus. Gut (1971) 1.11
The role of smoking and alcohol in metaplasia and cancer risk in Barrett's columnar lined oesophagus. Gut (1993) 1.11
Effect of chronic and acute cigarette smoking on the pharyngoglottal closure reflex. Gut (2002) 1.07
Outpatient endoscopic survey of smoking and peptic ulcer. Gut (1986) 0.95
Aerophagia and gastroesophageal reflux disease in patients using continuous positive airway pressure: a preliminary observation. J Clin Sleep Med (2008) 0.93
Effect of systemic alcohol and nicotine on airway protective reflexes. Am J Gastroenterol (2009) 0.92
Gastroesophageal reflux disease is uncommon in Asia: evidence and possible explanations. World J Gastroenterol (1999) 0.89
Association of laryngeal cancer with previous gastric resection. Ann Surg (2004) 0.89
Protective role of aerodigestive reflexes against aspiration: study on subjects with impaired and preserved reflexes. Gastroenterology (2011) 0.85
Symposium on gastrooesophageal reflux and its complications. 6. Surgical treatment. Gut (1973) 0.84
Gastroesophageal reflux and idiopathic pulmonary fibrosis: a review. Pulm Med (2010) 0.83
Oesophageal histology in long term users of non-steroidal anti-inflammatory drugs. J Clin Pathol (1994) 0.82
Continuous taurocholic acid exposure promotes esophageal squamous cell carcinoma progression due to reduced cell loss resulting from enhanced vascular development. PLoS One (2014) 0.78
Gastroesophageal reflux disease and postlaryngectomy tracheoesophageal fistula. Eur Arch Otorhinolaryngol (2012) 0.77
A randomized, double-blind comparison of two different coffee-roasting processes on development of heartburn and dyspepsia in coffee-sensitive individuals. Dig Dis Sci (2003) 0.76
Cigarette smoking: its relationship to other diseases. J Natl Med Assoc (1973) 0.75
Helicobacter pylori and smoking: two additive risk factors for organic dyspepsia. Yale J Biol Med (1999) 0.75
Nocturnal arousals in a middle-aged woman. J Clin Sleep Med (2014) 0.75
Letter: Cigarette smoking and chest pain. Br Med J (1976) 0.75
Common problems of the esophagus. Can Fam Physician (1973) 0.75
Gastroesophageal reflux symptoms in Turkish people: a positive correlation with abdominal obesity in women. North Clin Istanb (2015) 0.75
Acute effect of nicotine patch on gastric emptying of liquid and solid contents in healthy subjects. Dig Dis Sci (1999) 0.75
Classification of oesophageal motility abnormalities. Gut (2001) 4.86
Symptomatic gastroesophageal reflux: incidence and precipitating factors. Am J Dig Dis (1976) 3.71
The symptom index: a clinically important parameter of ambulatory 24-hour esophageal pH monitoring. Am J Gastroenterol (1988) 3.53
Simultaneous intraesophageal impedance and pH measurement of acid and nonacid gastroesophageal reflux: effect of omeprazole. Gastroenterology (2001) 3.35
Esophageal manometry in 95 healthy adult volunteers. Variability of pressures with age and frequency of "abnormal" contractions. Dig Dis Sci (1987) 3.07
Hormonal control of gastroesophageal-sphincter strength. N Engl J Med (1970) 2.74
Gastroesophageal reflux. Pathogenesis, diagnosis, and therapy. Ann Intern Med (1982) 2.63
The accuracy of the physical examination in the diagnosis of suspected ascites. JAMA (1982) 2.35
Cimetidine in the treatment of symptomatic gastroesophageal reflux: a double blind controlled trial. Gastroenterology (1978) 2.21
Review article: an analysis of the efficacy, perforation rates and methods used in pneumatic dilation for achalasia. Aliment Pharmacol Ther (2011) 2.13
Evidence of gender differences in esophageal pain threshold. Am J Gastroenterol (1995) 2.09
Baclofen decreases acid and non-acid post-prandial gastro-oesophageal reflux measured by combined multichannel intraluminal impedance and pH. Aliment Pharmacol Ther (2003) 2.05
Esophageal testing of patients with noncardiac chest pain or dysphagia. Results of three years' experience with 1161 patients. Ann Intern Med (1987) 2.02
Ineffective esophageal motility (IEM): the primary finding in patients with nonspecific esophageal motility disorder. Dig Dis Sci (1997) 1.99
Successful elimination of reflux symptoms does not insure adequate control of acid reflux in patients with Barrett's esophagus. Am J Gastroenterol (1994) 1.97
Ambulatory 24-hour esophageal pH monitoring. Reproducibility and variability of pH parameters. Dig Dis Sci (1988) 1.91
Nocturnal recovery of gastric acid secretion with twice-daily dosing of proton pump inhibitors. Am J Gastroenterol (1998) 1.90
Abnormal sensory perception in patients with esophageal chest pain. Gastroenterology (1986) 1.87
Esophageal chest pain: current controversies in pathogenesis, diagnosis, and therapy. Ann Intern Med (1989) 1.84
Diffuse esophageal spasm. A rare motility disorder not characterized by high-amplitude contractions. Dig Dis Sci (1991) 1.81
Lower esophageal sphincter pressure changes after food ingestion. Gastroenterology (1972) 1.78
Rationale and efficacy of conservative therapy for gastroesophageal reflux disease. Arch Intern Med (1991) 1.77
Does the intraesophageal pH probe accurately detect acid reflux? Simultaneous recording with two pH probes in humans. Dig Dis Sci (1989) 1.72
Prolonged ambulatory pH monitoring in patients with persistent gastroesophageal reflux disease symptoms: testing while on therapy identifies the need for more aggressive anti-reflux therapy. Am J Gastroenterol (1996) 1.72
Combined multichannel intraluminal impedance-pH monitoring to select patients with persistent gastro-oesophageal reflux for laparoscopic Nissen fundoplication. Br J Surg (2006) 1.66
Updated guidelines for the diagnosis and treatment of gastroesophageal reflux disease. The Practice Parameters Committee of the American College of Gastroenterology. Am J Gastroenterol (1999) 1.65
Gastro-oesophageal reflux associated with nocturnal gastric acid breakthrough on proton pump inhibitors. Aliment Pharmacol Ther (1998) 1.65
Ineffective esophageal motility: the most common motility abnormality in patients with GERD-associated respiratory symptoms. Am J Gastroenterol (1999) 1.63
Endoluminal ultrasonography of the distal esophagus in systemic sclerosis. Gastroenterology (1993) 1.60
Pulmonary symptoms associated with gastroesophageal reflux: use of ambulatory pH monitoring to diagnose and to direct therapy. Am J Gastroenterol (1996) 1.58
Diffuse esophageal spasm: a reappraisal. Ann Intern Med (1984) 1.57
Achalasia and diffuse esophageal spasm. Arch Intern Med (1976) 1.52
High amplitude, peristaltic esophageal contractions associated with chest pain and/or dysphagia. Gastroenterology (1979) 1.51
Gastroesophageal reflux in runners. Characteristics and treatment. Ann Intern Med (1990) 1.49
Bedtime H2 blockers improve nocturnal gastric acid control in GERD patients on proton pump inhibitors. Aliment Pharmacol Ther (2001) 1.43
Effects of octreotide on esophageal visceral perception and cerebral evoked potentials induced by balloon distension. Am J Gastroenterol (1999) 1.43
Effect of dry swallows and wet swallows of different volumes on esophageal peristalsis. J Appl Physiol (1975) 1.42
Pneumatic balloon dilation in achalasia: a prospective comparison of balloon distention time. Am J Gastroenterol (1998) 1.39
Guidelines for the diagnosis and treatment of gastroesophageal reflux disease. Practice Parameters Committee of the American College of Gastroenterology. Arch Intern Med (1995) 1.39
Prospective manometric evaluation with pharmacologic provocation of patients with suspected esophageal motility dysfunction. Gastroenterology (1983) 1.39
Experimental esophagitis in cats impairs lower esophageal sphincter pressure. Gastroenterology (1975) 1.38
Persistent acid secretion during omeprazole therapy: a study of gastric acid profiles in patients demonstrating failure of omeprazole therapy. Am J Gastroenterol (1996) 1.34
Caffeine and the lower esophageal sphincter. Am J Dig Dis (1972) 1.33
Altered gastric emptying and secretion in primary anorexia nervosa. Gastroenterology (1979) 1.33
Radiofrequency energy delivery to the gastroesophageal junction for the treatment of GERD. Gastrointest Endosc (2001) 1.33
Prospective randomized comparison of pneumatic dilatation technique in patients with idiopathic achalasia. Dig Dis Sci (1999) 1.32
Normal and abnormal proximal esophageal acid exposure: results of ambulatory dual-probe pH monitoring. Am J Gastroenterol (1993) 1.31
A comparison of high and low fat meals on postprandial esophageal acid exposure. Am J Gastroenterol (1989) 1.28
Apparent complete lower esophageal sphincter relaxation in achalasia. Gastroenterology (1986) 1.25
Respiratory complications of gastroesophageal reflux. Arch Intern Med (1985) 1.23
Pneumatic dilatation is effective long-term treatment for achalasia. Dig Dis Sci (1998) 1.23
Evidence for diminished visceral pain with aging: studies using graded intraesophageal balloon distension. Am J Physiol (1997) 1.22
The spleen percussion sign. A useful diagnostic technique. Ann Intern Med (1967) 1.22
Esophageal function testing using multichannel intraluminal impedance. Am J Physiol Gastrointest Liver Physiol (2001) 1.21
Esophageal radiography and manometry: correlation in 172 patients with dysphagia. AJR Am J Roentgenol (1987) 1.20
Gastric alkalinization. Effect on lower-esophageal-sphincter pressure and serum gastrin. N Engl J Med (1974) 1.20
Lower esophageal sphincter response to gastric alkalinization. A new mechanism for treatment of heartburn with antacids. Ann Intern Med (1971) 1.19
Imipramine decreases oesophageal pain perception in human male volunteers. Gut (1998) 1.19
Ambulatory 24-hour esophageal pH monitoring. Technology searching for a clinical application. J Clin Gastroenterol (1986) 1.18
Review article: complete gastro-oesophageal reflux monitoring - combined pH and impedance. Aliment Pharmacol Ther (2006) 1.17
Eastimation of liver size by percussion in normal individuals. Ann Intern Med (1969) 1.17
Ranitidine controls nocturnal gastric acid breakthrough on omeprazole: a controlled study in normal subjects. Gastroenterology (1998) 1.17
Vigorous achalasia: original description requires minor change. J Clin Gastroenterol (2001) 1.16
Effect of head position on the dynamics of the upper esophageal sphincter and pharynx. Dysphagia (1993) 1.16
Globus sensation is associated with hypertensive upper esophageal sphincter but not with gastroesophageal reflux. Dig Dis Sci (1998) 1.15
Fundoplication eliminates chronic cough due to non-acid reflux identified by impedance pH monitoring. Thorax (2005) 1.15
Optimal dosing of omeprazole 40 mg daily: effects on gastric and esophageal pH and serum gastrin in healthy controls. Am J Gastroenterol (1996) 1.15
Pharyngeal and upper esophageal sphincter manometry in the evaluation of dysphagia. J Clin Gastroenterol (2001) 1.14
Muscle anatomy of the human esophagus. J Clin Gastroenterol (1986) 1.14
Modern solid state computerized manometry of the pharyngoesophageal segment. Dysphagia (1993) 1.13
Oral nifedipine in the treatment of noncardiac chest pain in patients with the nutcracker esophagus. Gastroenterology (1987) 1.13
Relationship of radionuclide liquid bolus transport and esophageal manometry. J Lab Clin Med (1987) 1.13
Inhibition of the lower oesophageal sphincter by fat--a mechanism for fatty food intolerance. Gut (1973) 1.11
Evaluation of dysphagia: a careful history is crucial. Dysphagia (1987) 1.11
Pulmonary aspiration as a consequence of gastroesophageal reflux: a diagnostic approach. Dig Dis Sci (1979) 1.11
Abnormal esophageal pressures in reflux esophagitis: cause or effect? Am J Gastroenterol (1986) 1.11
Effects of position on oesophageal function: studies using combined manometry and multichannel intraluminal impedance. Neurogastroenterol Motil (2003) 1.10
Differential sensitivity of the human esophagus to pentagastrin. Am J Physiol (1972) 1.10
Review article: reflux and its consequences--the laryngeal, pulmonary and oesophageal manifestations. Conference held in conjunction with the 9th International Symposium on Human Pepsin (ISHP) Kingston-upon-Hull, UK, 21-23 April 2010. Aliment Pharmacol Ther (2011) 1.10
Effects of omeprazole versus placebo in treatment of noncardiac chest pain and gastroesophageal reflux. Dig Dis Sci (1997) 1.10
Swallowing and esophageal function in Parkinson's disease. Am J Gastroenterol (1995) 1.10
Esophageal mythology. JAMA (1978) 1.09
Clearance mechanisms of the aperistaltic oesophagus: the "pump gun" hypothesis. Gut (2005) 1.08
The acid suppression test for unexplained chest pain. Gastroenterology (1998) 1.07
Gastroesophageal reflux--the great imitator. West J Med (1988) 1.07
Effect of different recumbent positions on postprandial gastroesophageal reflux in normal subjects. Am J Gastroenterol (2000) 1.07
Prospective randomized comparison of Brown-McHardy and microvasive balloon dilators in treatment of achalasia. Am J Gastroenterol (1990) 1.07
On the genesis of heartburn. The effects of specific foods on the lower esophageal sphincter. Am J Dig Dis (1973) 1.06
The 198-Au liver scan. An index of portal-systemic collateral circulation in chronic liver disease. N Engl J Med (1966) 1.06
Oesophageal chest pain: a point of view. Gut (1984) 1.06
Edrophonium: a useful provocative test for esophageal chest pain. Ann Intern Med (1985) 1.05
Graded esophageal balloon distention. A new provocative test for noncardiac chest pain. Dig Dis Sci (1986) 1.04
Esophageal function in diabetes mellitus and its relation to peripheral neuropathy. Gastroenterology (1977) 1.04
Human esophageal response to rapid swallowing: muscle refractory period or neural inhibition? Am J Physiol (1981) 1.04
Nifedipine: a potent inhibitor of contractions in the body of the human esophagus. Studies in healthy volunteers and patients with the nutcracker esophagus. Gastroenterology (1985) 1.04
Gastroesophageal reflux induced by exercise in healthy volunteers. JAMA (1989) 1.03
Chronic hoarseness secondary to gastroesophageal reflux disease: documentation with 24-h ambulatory pH monitoring. Am J Gastroenterol (1989) 1.03
Pharyngeal and upper esophageal sphincter manometry in humans. Am J Physiol (1990) 1.02