Published in Circ Res on February 01, 1968
The effect of experimental cardiac arrhythmias of a new anticonvulsant agent, Kö 1173, and its comparison with phenytoin and procainamide. Br J Pharmacol (1970) 1.81
Effect of lidocaine on the electrophysiological properties of ventricular muscle and purkinje fibers. J Clin Invest (1970) 1.36
The electrophysiologic effects of low and high digoxin concentrations on isolated mammalian cardiac tissue: reversal by digoxin-specific antibody. J Clin Invest (1972) 0.97
Electrophysiological actions of mexiletine (Kö1173) on canine Purkinje fibres and ventricular muscle. Br J Pharmacol (1979) 0.90
The ionic basis of electrical activity in embryonic cardiac muscle. J Gen Physiol (1968) 0.85
Usefulness of Valsalva manoeuvre and cold pressor test for evaluation of arrhythmias in long QT syndrome. Br Heart J (1979) 0.83
Comparative antidysrhythmic and haemodynamic effects of orally or intravenously administered mexiletine and ORG 6001 in the anaesthetized rat. Br J Pharmacol (1981) 0.82
Inotropic actions of lignocaine and phenytoin. Br J Pharmacol (1971) 0.81
Investigations of the mode of action of a new antidysrhythmic drug, Kö 1173. Br J Pharmacol (1972) 0.81
Effect of lidocaine hydrochloride on membrane conductance in mammalian cardiac Purkinje fibers. J Clin Invest (1972) 0.80
Transverse spread and longitudinal dissociation in the distal A-V conducting system. J Clin Invest (1973) 0.79
Explanation for the discrepancy in reported cardiac electrophysiological actions of diphenylhydantoin and lignocaine. Br J Pharmacol (1971) 0.75
Enhanced Late Na and Ca Currents as Effective Antiarrhythmic Drug Targets. Front Pharmacol (2017) 0.75
[Diphenylhydantoin: a comparative study on normal cats and animals intoxicated with digitalis glycosides. Electrophysiological, hemodynamic, and electrocardiographic studies (author's transl)]. Basic Res Cardiol (1974) 0.75
Decreased heart rate variability and its association with increased mortality after acute myocardial infarction. Am J Cardiol (1987) 9.10
Heart rate variability: origins, methods, and interpretive caveats. Psychophysiology (1997) 7.81
Antipsychotic drugs: prolonged QTc interval, torsade de pointes, and sudden death. Am J Psychiatry (2001) 5.16
Prophylactic use of implanted cardiac defibrillators in patients at high risk for ventricular arrhythmias after coronary-artery bypass graft surgery. Coronary Artery Bypass Graft (CABG) Patch Trial Investigators. N Engl J Med (1997) 4.85
The intern and sleep loss. N Engl J Med (1971) 3.45
Heart-rate turbulence after ventricular premature beats as a predictor of mortality after acute myocardial infarction. Lancet (1999) 3.38
Baroreflex sensitivity and heart rate variability in the identification of patients at risk for life-threatening arrhythmias: implications for clinical trials. Circulation (2001) 2.50
The relationships among ventricular arrhythmias, left ventricular dysfunction, and mortality in the 2 years after myocardial infarction. Circulation (1984) 2.45
Electrophysiologial and beta-receptor blocking effects of MJ 1999 on dog and rabbit cardiac tissue. Circ Res (1970) 1.96
The Canadian Constitution and its impact on psychiatry. Can J Psychiatry (1986) 1.92
Premature atrial stimulation as a key to the understanding of sinoatrial conduction in man. Presentation of data and critical review of the literature. Circulation (1973) 1.85
Comparison of 24-hour parasympathetic activity in endurance-trained and untrained young men. J Am Coll Cardiol (1992) 1.85
Neurosyphilis in a young man. Can J Psychiatry (1981) 1.82
Effect of long-term digoxin therapy on autonomic function in patients with chronic heart failure. J Am Coll Cardiol (1995) 1.63
Site of reentry in paroxysmal supraventricular tachycardia in man. Circulation (1971) 1.60
Relationship between the plasma level of diphenylhydantoin sodium and its cardiac antiarrhythmic effects. Circulation (1968) 1.50
Electrophysiological propertiesf the canine peripheral A-V conducting system. Circ Res (1970) 1.50
Association between ease of suppression of ventricular arrhythmia and survival. Circulation (1995) 1.48
Cardiac antiarrhythmic effect of imipramine hydrochloride. N Engl J Med (1977) 1.47
Characteristics of I(K) and its response to quinidine in experimental healed myocardial infarction. J Cardiovasc Electrophysiol (1999) 1.44
Comparison between invasive and non-invasive measurements of baroreflex sensitivity; implications for studies on risk stratification after a myocardial infarction. Eur Heart J (2000) 1.43
Mechanism of death and prevalence of myocardial ischemic symptoms in the terminal event after acute myocardial infarction. Am J Cardiol (1988) 1.42
Two components of the cardiac action potential. I. Voltage-time course and the effect of acetylcholine on atrial and nodal cells of the rabbit heart. J Gen Physiol (1969) 1.41
Pharmacologic management of ventricular arrhythmias after the cardiac arrhythmia suppression trial. Am J Cardiol (1990) 1.40
Evaluation of antiarrhythmic drug efficacy in patients with an ICD: unlimited potential or replete with complexity and problems? J Cardiovasc Electrophysiol (1999) 1.39
Action potential prolongation and induction of abnormal automaticity by low quinidine concentrations in canine Purkinje fibers. Relationship to potassium and cycle length. Circ Res (1985) 1.39
Observations on blood viscosity changes after acute myocardial infarction. Circulation (1975) 1.38
Comparison of paroxetine and nortriptyline in depressed patients with ischemic heart disease. JAMA (1998) 1.38
Cardiac arrhythmias during anesthesia and operation. Anesthesiology (1970) 1.38
Effect of lidocaine on the electrophysiological properties of ventricular muscle and purkinje fibers. J Clin Invest (1970) 1.36
Conduction of the cardiac impulse. 3. Characteristics of very slow conduction. J Gen Physiol (1972) 1.34
Risk stratification with low-level exercise testing 2 weeks after acute myocardial infarction. Circulation (1981) 1.33
Canine mitral complex. Ultrastructure and electromechanical properties. Circ Res (1972) 1.31
Clinical trial enrollers vs. nonenrollers: the Cardiac Arrhythmia Suppression Trial (CAST) Recruitment and Enrollment Assessment in Clinical Trials (REACT) project. Control Clin Trials (1996) 1.30
Two components of transient outward current in canine ventricular myocytes. Circ Res (1989) 1.29
Passive properties and membrane currents of canine ventricular myocytes. J Gen Physiol (1987) 1.28
Role of cardiac ATP-regulated potassium channels in differential responses of endocardial and epicardial cells to ischemia. Circ Res (1991) 1.27
Mechanisms of digitalis toxicity. Effects of ouabain on phase four of canine Purkinje fiber transmembrane potentials. Circulation (1973) 1.27
Slow conduction and reentry in the ventricular conducting system. I. Return extrasystole in canine Purkinje fibers. Circ Res (1972) 1.27
Stability over time of variables measuring heart rate variability in normal subjects. Am J Cardiol (1991) 1.27
Conduction of the cardiac impulse. 1. Delay, block, and one-way block in depressed Purkinje fibers. Circ Res (1971) 1.26
An analysis of the cost effectiveness of the implantable defibrillator. Circulation (1990) 1.26
Electrophysiological properties of cardiac muscle in the anterior mitral valve leaflet and the adjacent atrium in the dog. Possible implications for the genesis of atrial dysrhythmias. Circ Res (1973) 1.25
Spontaneous and induced reentrant tachycardia. Ann Intern Med (1969) 1.24
Differences in transient outward currents of feline endocardial and epicardial myocytes. Circ Res (1990) 1.23
Cardiovascular effects of therapeutic doses of tricyclic antidepressants. A review. Arch Gen Psychiatry (1981) 1.23
Effects of phentolamine on electrophysiologic properties of isolated canine purkinje fibers. J Pharmacol Exp Ther (1971) 1.23
Effect of mental stress throughout the day on cardiac autonomic control. Biol Psychol (1994) 1.22
The effect of extracellular potassium on the intracellular potassium ion activity and transmembrane potentials of beating canine cardiac Purkinje fibers. J Gen Physiol (1977) 1.21
Cellular mechanisms for cardiac arrhythmias. Circ Res (1981) 1.21
Ventricular arrhythmias in ischemic heart disease: mechanism, prevalence, significance, and management. Prog Cardiovasc Dis (1977) 1.19
Appraisal of the effects of catecholamines on cardiac electrical activity. Ann N Y Acad Sci (1967) 1.18
Simultaneous recording of action potentials from endocardium and epicardium during ischemia in the isolated cat ventricle: relation of temporal electrophysiologic heterogeneities to arrhythmias. Circulation (1986) 1.17
The P wave and P-R interval. Effects of the site of origin of atrial depolarization. Circulation (1970) 1.17
Diminished transient outward currents in rat hypertrophied ventricular myocytes. Circ Res (1994) 1.17
Effect of atenolol and diltiazem on heart period variability in normal persons. J Am Coll Cardiol (1991) 1.17
Interrelationship between automaticity and conduction in Purkinje fibers. Circ Res (1967) 1.17
Electroconvulsive therapy--a current view. Can Med Assoc J (1984) 1.16
The use of procaine amide and lidocaine in the treatment of cardiac arrhythmias. Prog Cardiovasc Dis (1969) 1.15
Risk stratification after acute myocardial infarction. Am J Cardiol (1978) 1.14
Electrical restitution process in dispersed canine cardiac Purkinje and ventricular cells. Am J Physiol (1987) 1.14
Cardiac autonomic control and hostility in healthy subjects. Am J Cardiol (1994) 1.13
Mechanisms of bradycardia induced by digitalis substances. Am J Physiol (1967) 1.12
Prevalence, characteristics and significance of ventricular tachycardia (three or more complexes) detected with ambulatory electrocardiographic recording in the late hospital phase of acute myocardial infarction. Am J Cardiol (1981) 1.11
Efficient estimation of the heart period power spectrum suitable for physiologic or pharmacologic studies. Am J Cardiol (1990) 1.11
Enrollment in clinical trials: institutional factors affecting enrollment in the cardiac arrhythmia suppression trial (CAST). Control Clin Trials (1992) 1.11
Effects of nifedipine on electrical activity of cardiac cells. Am J Cardiol (1980) 1.10
Electrophysiology and pharmacology of cardiac arrhythmias. V. Cardiac antiarrhythmic effects of lidocaine. Am Heart J (1975) 1.10
Ventriculo-atrial conduction in man. Circulation (1970) 1.10
Electrophysiologic properties of isolated preparations of human atrial myocardium. Circ Res (1972) 1.10
Etiology of right bundle-branch block in patients undergoing total correction of tetralogy of Fallot. Circulation (1971) 1.09
Genesis of cardiac arrhythmias. Circulation (1973) 1.09
Specialized cardiac conduction system. Improved electrophysiologic identification technique at surgery. Arch Surg (1970) 1.09
Clinical characteristics of imipramine-induced orthostatic hypotension. Lancet (1979) 1.09
Intermittent intravenous procaine amide to treat ventricular arrhythmias. Correlation of plasma concentration with effect on arrhythmia, electrocardiogram, and blood pressure. Ann Intern Med (1973) 1.07
Dissimilar length--tension relations of canine ventricular muscle and false tendon: electrophysiologic alterations accompanying deformation. J Mol Cell Cardiol (1979) 1.07
Involuntary hospitalization related to employment status. Can J Psychiatry (1979) 1.06
Treatment of ventricular arrhythmias by United States cardiologists: a survey before the Cardiac Arrhythmia Suppression Trial results were available. Am J Cardiol (1990) 1.06
Correlation between effects of ouabain on the canine electrocardiogram and transmembrane potentials of isolated Purkinje fibers. Circulation (1973) 1.05
Conduction of the cardiac impulse. II. Summation and inhibition. Circ Res (1971) 1.05
Potassium rectifier currents differ in myocytes of endocardial and epicardial origin. Circ Res (1992) 1.05
Specialized conducting fibers in the interatrial band. Circ Res (1966) 1.05
Autonomic control of cardiac rhythm. Bull N Y Acad Med (1967) 1.03
Electrophysiological properties of the rabbit sinoatrial perinodal fibers. Circ Res (1972) 1.03
The influence of molecular form of local anesthetic-type antiarrhythmic agents on reduction of the maximum upstroke velocity of canine cardiac Purkinje fibers. Circ Res (1983) 1.03
Effect of H+ on ATP-regulated K+ channels in feline ventricular myocytes. Am J Physiol (1991) 1.02
Electrophysiology and pharmacology of cardiac arrhythmias. VI. Cardiac effects of verapamil. Am Heart J (1975) 1.02
The effect of oral quinidine on intraventricular conduction in man: correlation of plasma quinidine with changes in QRS duration. Am Heart J (1970) 1.01
Effects on the canine P wave of discrete lesions in the specialized atrial tracts. Circ Res (1971) 1.01
Analysis of prognostic significance of ventricular arrhythmias after myocardial infarction. Shortcomings of Lown grading system. Br Heart J (1981) 1.00
Early afterdepolarizations and triggered activity induced by cocaine. A possible mechanism of cocaine arrhythmogenesis. Circulation (1992) 1.00
Electrophysiological properties and responses to simulated ischemia in cat ventricular myocytes of endocardial and epicardial origin. Circ Res (1990) 1.00
Electrophysiologic evaluation of sinus node function in patients with sinus node dysfunction. Circulation (1976) 0.99
Slow conduction and reentry in the ventricular conducting system. II. Single and sustained circus movement in networks of canine and bovine Purkinje fibers. Circ Res (1972) 0.99
Amrinone relaxes potassium-induced contracture of failing right ventricular muscle of cats. J Cardiovasc Pharmacol (1983) 0.99
Comparison of spontaneous vs. metronome-guided breathing on assessment of vagal modulation using RR variability. Am J Physiol Heart Circ Physiol (2001) 0.99
The safety of tricyclic antidepressants in cardiac patients. Risk-benefit reconsidered. JAMA (1993) 0.99