Published in Nature on February 03, 1968
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Elevated concentration of adenosine 3':5'-cyclic monophosphate in intestinal mucosa after treatment with cholera toxin. Proc Natl Acad Sci U S A (1970) 3.41
Effect of cholera enterotoxin on ion transport across isolated ileal mucosa. J Clin Invest (1972) 3.28
Localization of the action of cholera toxin on adenyl cyclase in mucosal epithelial cells of rabbit intestine. J Clin Invest (1972) 1.46
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The pathophysiology of cholera. Bull N Y Acad Med (1971) 1.20
Stimulation of steroid secretion in adrenal tumor cells by choleragen. Proc Natl Acad Sci U S A (1973) 1.19
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Cholera toxin activation of adenylate cyclase in cancer cell membrane fragments. Proc Natl Acad Sci U S A (1975) 1.14
Small fragments from the A subunit of cholera toxin capable of activating adenylate cyclase. Proc Natl Acad Sci U S A (1976) 1.00
Stimulation of electrolyte secretion in rabbit colon by adenosine. J Physiol (1984) 0.99
The effect of adenosine triphosphate on the transmural potential in rat small intestine. J Physiol (1970) 0.94
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Cholera toxin-induced secretion in rats is reduced by a soluble fiber, gum arabic. Dig Dis Sci (2000) 0.84
Stimulation of intestinal mucosal adenyl cyclase by cholera enterotoxin and prostaglandins. J Clin Invest (1971) 6.09
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Use of an inert marker (phenol red) to improve accuracy in gastric secretion studies. Gut (1969) 3.35
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Ion transport in rabbit ileal mucosa. II. Effects of cyclic 3', 5'-AMP. Am J Physiol (1971) 2.38
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Clinical and molecular delineation of the 17q21.31 microdeletion syndrome. J Med Genet (2008) 2.09
Mechanism of active chloride secretion by shark rectal gland: role of Na-K-ATPase in chloride transport. Am J Physiol (1977) 2.08
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Bradykinin receptor-mediated chloride secretion in intestinal function. Nature (1982) 1.86
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Antacid titration in the prevention of acute gastrointestinal bleeding: a controlled, randomized trial in 100 critically ill patients. N Engl J Med (1978) 1.77
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Antacid versus cimetidine in preventing acute gastrointestinal bleeding. A randomized trial in 75 critically ill patients. N Engl J Med (1980) 1.75
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Respiratory failure, hypotension, sepsis, and jaundice. A clinical syndrome associated with lethal hemorrhage from acute stress ulceration of the stomach. Am J Surg (1969) 1.67
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Isoperistaltic jejunal interposition for intractable postgastrectomy alkaline reflux gastritis. J Am Coll Surg (1995) 1.62
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Mode of action of cholera toxin: stabilization of catecholamine-sensitive adenylate cyclase in turkey erythrocytes. Proc Natl Acad Sci U S A (1974) 1.57
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Mode of action of heat-stable Escherichia coli enterotoxin. Tissue and subcellular specificities and role of cyclic GMP. Biochim Biophys Acta (1980) 1.55
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Restitution of the surface epithelium of the in vitro frog gastric mucosa after damage with hyperosmolar sodium chloride. Morphologic and physiologic characteristics. Gastroenterology (1982) 1.53
Localization of tumor necrosis factor receptors in the synovial tissue and cartilage-pannus junction in patients with rheumatoid arthritis. Implications for local actions of tumor necrosis factor alpha. Arthritis Rheum (1992) 1.53
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Germline mutation of the tumour suppressor PTEN in Proteus syndrome. J Med Genet (2002) 1.50
Catecholamine effects on cyclic AMP levels and ion secretion in rabbit ileal mucosa. Am J Physiol (1975) 1.50
Effect of bile salts and related compounds on isolated esophageal mucosa. Surgery (1980) 1.46
Bradykinin-stimulated electrolyte secretion in rabbit and guinea pig intestine. Involvement of arachidonic acid metabolites. J Clin Invest (1983) 1.45
Characteristics and functions of Na-K-Cl cotransport in epithelial tissues. Am J Physiol (1987) 1.44
Localization of interleukin-1 alpha, type 1 interleukin-1 receptor and interleukin-1 receptor antagonist in the synovial membrane and cartilage/pannus junction in rheumatoid arthritis. Br J Rheumatol (1992) 1.44
Alanine transport across isolated rabbit ileum. Biochim Biophys Acta (1967) 1.41
Inhibition of Na+,K+-ATPase by interferon gamma down-regulates intestinal epithelial transport and barrier function. Gastroenterology (2001) 1.40
Na+-K+-Cl- co-transport in the intestine of a marine teleost. Nature (1982) 1.39
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The bone scan in primary care: diagnostic pitfalls. J Am Board Fam Pract (1992) 1.38
Experimental diarrhea: salmonella enterocolitis inthe rat. J Infect Dis (1970) 1.37
Management of septic arthritis: a systematic review. Ann Rheum Dis (2007) 1.37
Prospective comparative study of patients with culture proven and high suspicion of adult onset septic arthritis. Ann Rheum Dis (2003) 1.35
Ductal carcinoma in situ (intraductal carcinoma) of the breast. N Engl J Med (1988) 1.33
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Improved method for studying the rate of human gastric secretory activity under varying conditions of acid-base balance. Surg Forum (1966) 1.31
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Diagnostic peritoneal lavage analysis: should trauma guidelines be revised? Emerg Med J (2002) 1.30
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Molecular cloning and characterization of p64, a chloride channel protein from kidney microsomes. J Biol Chem (1993) 1.28
Control of guinea pig intestinal electrolyte secretion by a delta-opiate receptor. Proc Natl Acad Sci U S A (1980) 1.27
Mechanisms for rapid re-epithelialization of the gastric mucosal surface. Annu Rev Physiol (1985) 1.26
Intellectual outcome in children with maple syrup urine disease. J Pediatr (1991) 1.26
Isolation of nontoxinogenic mutants of Vibrio cholerae in a colorimetric assay for cholera toxin using the S49 mouse lymphosarcoma cell line. J Infect Dis (1978) 1.26
Stimulation of colonic secretion by lipoxygenase metabolites of arachidonic acid. Science (1982) 1.26
The mechanism of injury in blunt traumatic rupture of the aorta. Eur J Cardiothorac Surg (2002) 1.26
Agrobacterium radiobacter prosthetic valve endocarditis. Ann Intern Med (1980) 1.26
Permeability of the human gastric mucosa. Alteration by Acetylsalicylic acid and ethanol. N Engl J Med (1971) 1.26
Kimberlite ascent and eruption. Nature (2007) 1.24
Mechanisms of action of cholera and Escherichia coli enterotoxins. Am J Clin Nutr (1979) 1.23
Duodenojejunostomy for the pancreaticobiliary complications of duodenal diverticulum. Ann Surg (1985) 1.23
Ion transport in rabbit ileal mucosa. IV. Bicarbonate secretion. Am J Physiol (1973) 1.21
In vitro antisecretory effects of trifluoperazine and other neuroleptics in rabbit and human small intestine. Gastroenterology (1980) 1.19
Time-course of local recurrence following conservative surgery and radiotherapy for early stage breast cancer. Int J Radiat Oncol Biol Phys (1988) 1.19
When typical is atypical: mycobacterial infection mimicking cutaneous vasculitis. Rheumatology (Oxford) (2002) 1.18
Transforming growth factor alpha inhibits secretion of gastric acid. Proc Natl Acad Sci U S A (1986) 1.14
The gastric mucosal barrier: clinical and experimental studies in critically ill and normal man, and in the rabbit. Ann Surg (1970) 1.14
Effects of cycloheximide on the response of intestinal mucosa to cholera enterotoxin. J Clin Invest (1973) 1.14
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A proinflammatory role of IL-18 in the development of spontaneous autoimmune disease. J Immunol (2001) 1.14
Detection of cytokines at the site of tuberculin-induced delayed-type hypersensitivity in man. Clin Exp Immunol (1992) 1.13
A revised potential-energy surface for molecular mechanics studies of carbohydrates. Carbohydr Res (1988) 1.13
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Fatal hemorrhage from the innominate artery after tracheostomy. Ann Surg (1965) 1.12
Recommended guidelines for the treatment of chemotherapy-induced diarrhea. J Clin Oncol (1998) 1.11
Experimental diarrhea. I. Intestinal water and electrolyte transport in rat salmonella enterocolitis. Gastroenterology (1971) 1.11
Secretion of electrolytes and water by the guinea pig small intestine in vivo. Am J Physiol (1968) 1.10
Studies of the pH gradient and thickness of frog gastric mucus gel. Gastroenterology (1983) 1.10
Gastroenteritis: etiology, pathophysiology and clinical manifestations. Medicine (Baltimore) (1979) 1.09
Effect of simulated systemic administration of aspirin, salicylate, and indomethacin on amphibian gastric mucosa. Gastroenterology (1986) 1.09
In vitro effects of somatostatin on ion transport in rabbit intestine. Am J Physiol (1980) 1.09
Effects of heat-stable enterotoxin of Yersinia enterocolitica on ion transport and cyclic guanosine 3',5'-monophosphate metabolism in rabbit ileum. Infect Immun (1979) 1.08
Coupled sodium-chloride influx across brush border of flounder intestine. J Membr Biol (1979) 1.07
Effects of epidermal growth factor on acid secretion from guinea pig gastric mucosa: in vitro analysis. Gastroenterology (1985) 1.07
Edema of the arm as a function of the extent of axillary surgery in patients with stage I-II carcinoma of the breast treated with primary radiotherapy. Int J Radiat Oncol Biol Phys (1986) 1.07
Transforming growth factor-beta 1 in rheumatoid synovial membrane and cartilage/pannus junction. Clin Exp Immunol (1991) 1.07
CCDC22: a novel candidate gene for syndromic X-linked intellectual disability. Mol Psychiatry (2011) 1.07