Published in J Cell Biol on November 01, 1978
Implications of treadmilling for the stability and polarity of actin and tubulin polymers in vivo. J Cell Biol (1980) 4.39
Lattice defects in microtubules: protofilament numbers vary within individual microtubules. J Cell Biol (1992) 2.28
Cross-sectional structure of the central mitotic spindle of Diatoma vulgare. Evidence for specific interactions between antiparallel microtubules. J Cell Biol (1979) 2.04
Genetically separable functions of the MEC-17 tubulin acetyltransferase affect microtubule organization. Curr Biol (2012) 1.83
pH regulates the polymerization of actin in the sea urchin egg cortex. J Cell Biol (1979) 1.75
Structural and functional diversity in the neuronal microtubules of Caenorhabditis elegans. J Cell Biol (1982) 1.70
Heterogeneity of microtubule-associated protein 2 during rat brain development. Proc Natl Acad Sci U S A (1984) 1.54
Reassembly of flagellar B (alpha beta) tubulin into singlet microtubules: consequences for cytoplasmic microtubule structure and assembly. J Cell Biol (1981) 1.29
Microtubule dynamics investigated by microinjection of Paramecium axonemal tubulin: lack of nucleation but proximal assembly of microtubules at the kinetochore during prometaphase. J Cell Biol (1989) 1.19
The alpha subunit of sea urchin sperm outer arm dynein mediates structural and rigor binding to microtubules. J Cell Biol (1992) 1.13
Microtubule-associated protein 2 within axons of spinal motor neurons: associations with microtubules and neurofilaments in normal and beta,beta'-iminodipropionitrile-treated axons. J Cell Biol (1985) 1.09
Strongylocentrotus purpuratus spindle tubulin. I. Characteristics of its polymerization and depolymerization in vitro. J Cell Biol (1982) 1.07
Arrangement of tubulin subunits and microtubule-associated proteins in the central-pair microtubule apparatus of squid (Loligo pealei) sperm flagella. J Cell Biol (1981) 1.07
One-step purification of assembly-competent tubulin from diverse eukaryotic sources. Mol Biol Cell (2012) 1.03
Structural basis of motility in the microtubular axostyle: implications for cytoplasmic microtubule structure and function. J Cell Biol (1980) 0.97
Disassembly and reconstitution of a membrane-microtubule complex. J Cell Biol (1984) 0.96
Polarity of dynein-microtubule interactions in vitro: cross-bridging between parallel and antiparallel microtubules. J Cell Biol (1981) 0.96
Three-dimensional structure of a membrane-microtubule complex. J Cell Biol (1984) 0.87
Purification and characterization of oocyte cytoplasmic tubulin and meiotic spindle tubulin of the surf clam Spisula solidissima. J Cell Biol (1984) 0.86
Analysis of the spatial organization of microtubule-associated proteins. J Cell Biol (1986) 0.85
High resolution two-dimensional electrophoresis of proteins. J Biol Chem (1975) 133.45
Nutritional studies with Chlamydomonas reinhardi. Ann N Y Acad Sci (1953) 12.36
A simplified method for the quantitative assay of small amounts of protein in biologic material. Anal Biochem (1973) 10.11
Association of high-molecular-weight proteins with microtubules and their role in microtubule assembly in vitro. Proc Natl Acad Sci U S A (1975) 6.35
Structural polarity and directional growth of microtubules of Chlamydomonas flagella. J Mol Biol (1974) 4.80
Arrangement of subunits in flagellar microtubules. J Cell Sci (1974) 4.77
The mechanism of action of colchicine. Colchicine binding properties of sea urchin sperm tail outer doublet tubulin. J Cell Biol (1973) 1.68
Tannic acid-stained microtubules with 12, 13, and 15 protofilaments. J Cell Biol (1975) 1.63
Alterations in number of protofilaments in microtubules assembled in vitro. J Cell Biol (1978) 1.52
Directionality and rate of assembly of chick brain tubulin onto pieces of neurotubules, flagellar axonemes, and basal bodies. Ann N Y Acad Sci (1975) 1.51
Reassociation of microtubule protein. J Mol Biol (1968) 1.41
Microtubules: structure, chemistry, and function. Physiol Rev (1976) 1.34
The bound nucleotides of the isolated microtubules of sea-urchin sperm flagella and their possible role in flagellar movement. Exp Cell Res (1968) 1.18
The in vitro assembly of tubulins from sea-urchin eggs and rat brain: use of heterologous seeds. J Cell Sci (1974) 1.00
Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology. Proc Natl Acad Sci U S A (1986) 10.13
Flagellar elongation and shortening in Chlamydomonas. The use of cycloheximide and colchicine to study the synthesis and assembly of flagellar proteins. J Cell Biol (1969) 8.72
The distribution of tau in the mammalian central nervous system. J Cell Biol (1985) 7.47
Chlamydomonas kinesin-II-dependent intraflagellar transport (IFT): IFT particles contain proteins required for ciliary assembly in Caenorhabditis elegans sensory neurons. J Cell Biol (1998) 7.22
Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella. J Cell Biol (2000) 7.04
Chlamydomonas flagella. I. Isolation and electrophoretic analysis of microtubules, matrix, membranes, and mastigonemes. J Cell Biol (1972) 6.94
A motility in the eukaryotic flagellum unrelated to flagellar beating. Proc Natl Acad Sci U S A (1993) 6.50
Simple method for quantitive densitometry of polyacrylamide gels using fast green. Anal Biochem (1970) 6.03
Cyclic AMP-dependent endogenous phosphorylation of a microtubule-associated protein. Proc Natl Acad Sci U S A (1975) 5.25
The periodic association of MAP2 with brain microtubules in vitro. J Cell Biol (1979) 4.97
The Chlamydomonas kinesin-like protein FLA10 is involved in motility associated with the flagellar membrane. J Cell Biol (1995) 4.78
Flagellar regeneration in protozoan flagellates. J Cell Biol (1967) 4.57
Flagellar elongation and shortening in Chlamydomonas. IV. Effects of flagellar detachment, regeneration, and resorption on the induction of flagellar protein synthesis. J Cell Biol (1978) 4.36
Neurofibrillary tangles of Alzheimer disease share antigenic determinants with the axonal microtubule-associated protein tau (tau) Proc Natl Acad Sci U S A (1986) 4.26
Microtubule-associated proteins and the stimulation of tubulin assembly in vitro. Biochemistry (1976) 4.12
Ultrastructural localization of the high molecular weight proteins associated with in vitro-assembled brain microtubules. J Cell Biol (1975) 3.75
Chlamydomonas alpha-tubulin is posttranslationally modified by acetylation on the epsilon-amino group of a lysine. Biochemistry (1985) 3.75
Localization of intraflagellar transport protein IFT52 identifies basal body transitional fibers as the docking site for IFT particles. Curr Biol (2001) 3.58
Directionality of brain microtubule assembly in vitro. Proc Natl Acad Sci U S A (1974) 3.45
Assembly of chick brain tubulin onto flagellar microtubules from Chlamydomonas and sea urchin sperm. Proc Natl Acad Sci U S A (1975) 3.36
A motile Chlamydomonas flagellar mutant that lacks outer dynein arms. J Cell Biol (1985) 3.09
Chlamydomonas alpha-tubulin is posttranslationally modified in the flagella during flagellar assembly. J Cell Biol (1983) 3.09
Multiple alpha- and beta-tubulin genes in Chlamydomonas and regulation of tubulin mRNA levels after deflagellation. Cell (1981) 3.02
Cilia regeneration in Tetrahymena and its inhibition by colchicine. J Cell Biol (1969) 2.97
Increased levels of mRNAs for tubulin and other flagellar proteins after amputation or shortening of Chlamydomonas flagella. Cell (1980) 2.83
Inhibition of neuronal maturation in primary hippocampal neurons from tau deficient mice. J Cell Sci (2001) 2.82
Intraflagellar transport balances continuous turnover of outer doublet microtubules: implications for flagellar length control. J Cell Biol (2001) 2.81
Comparison of the microtubule proteins of neuroblastoma cells, brain, and Chlamydomonas flagella. Proc Natl Acad Sci U S A (1971) 2.68
Polarity of flagellar assembly in Chlamydomonas. J Cell Biol (1992) 2.66
Regulation of the synthesis and assembly of ciliary and flagellar proteins during regeneration. Annu Rev Cell Biol (1986) 2.63
Assembly of chick brain tubulin onto isolated basal bodies of Chlamydomonas reinhardi. Science (1974) 2.57
Dynein binds to and crossbridges cytoplasmic microtubules. Proc Natl Acad Sci U S A (1979) 2.49
Assembly of microtubules onto kinetochores of isolated mitotic chromosomes of HeLa cells. Proc Natl Acad Sci U S A (1975) 2.43
The structural basis of monoclonal antibody Alz50's selectivity for Alzheimer's disease pathology. J Biol Chem (1996) 2.41
Hydrofluoric acid-treated tau PHF proteins display the same biochemical properties as normal tau. J Biol Chem (1992) 2.40
mRNA abundance changes during flagellar regeneration in Chlamydomonas reinhardtii. Mol Cell Biol (1984) 2.39
Flagellar elongation and shortening in Chlamydomonas. III. structures attached to the tips of flagellar microtubules and their relationship to the directionality of flagellar microtubule assembly. J Cell Biol (1977) 2.27
Phosphorylation determines two distinct species of Tau in the central nervous system. Cell Motil Cytoskeleton (1987) 2.18
Flagellar elongation and shortening in chlamydomonas. II. Re-utilization of flagellar proteins. J Cell Biol (1970) 2.17
Molecular cloning and sequence analysis of the Chlamydomonas gene coding for radial spoke protein 3: flagellar mutation pf-14 is an ochre allele. J Cell Biol (1989) 2.11
Reversal of the posttranslational modification on Chlamydomonas flagellar alpha-tubulin occurs during flagellar resorption. J Cell Biol (1985) 2.04
Differential subcellular localization of tubulin and the microtubule-associated protein MAP2 in brain tissue as revealed by immunocytochemistry with monoclonal hybridoma antibodies. J Neurosci (1984) 2.03
The acetylation of alpha-tubulin and its relationship to the assembly and disassembly of microtubules. J Cell Biol (1986) 2.03
An autosomal recessive polycystic kidney disease gene homolog is involved in intraflagellar transport in C. elegans ciliated sensory neurons. Curr Biol (2001) 1.99
Oversized flagellar membrane protein in paralyzed mutants of Chlamydomonas reinhardrii. J Cell Biol (1980) 1.91
Cell cycle-dependent, in vitro assembly of microtubules onto pericentriolar material of HeLa cells. J Cell Biol (1979) 1.89
Molecular cloning and expression of flagellar radial spoke and dynein genes of Chlamydomonas. J Cell Biol (1986) 1.83
Chlamydomonas flagella. II. The distribution of tubulins 1 and 2 in the outer doublet microtubules. J Cell Biol (1972) 1.80
Multiple forms of tubulin in Polytomella and Chlamydomonas: evidence for a precursor of flagellar alpha-tubulin. J Cell Biol (1983) 1.79
Kinetics and regulation of de novo centriole assembly. Implications for the mechanism of centriole duplication. Curr Biol (2001) 1.73
A new kinesin-like protein (Klp1) localized to a single microtubule of the Chlamydomonas flagellum. J Cell Biol (1994) 1.69
Functional implications for the microtubule-associated protein tau: localization in oligodendrocytes. Proc Natl Acad Sci U S A (1995) 1.67
C-terminal inhibition of tau assembly in vitro and in Alzheimer's disease. J Cell Sci (2000) 1.67
Protein-protein interactions in the 18S ATPase of Chlamydomonas outer dynein arms. Cell Motil Cytoskeleton (1986) 1.66
Localization of calmodulin and dynein light chain LC8 in flagellar radial spokes. J Cell Biol (2001) 1.65
Localization of kinesin superfamily proteins to the connecting cilium of fish photoreceptors. J Cell Sci (1996) 1.64
Studies on the organization and localization of actin and myosin in neurons. J Cell Biol (1979) 1.64
Rapid changes in tubulin RNA synthesis and stability induced by deflagellation in Chlamydomonas. J Cell Biol (1984) 1.63
Free fatty acids stimulate the polymerization of tau and amyloid beta peptides. In vitro evidence for a common effector of pathogenesis in Alzheimer's disease. Am J Pathol (1997) 1.61
Rescue of a paralyzed-flagella mutant of Chlamydomonas by transformation. Proc Natl Acad Sci U S A (1990) 1.60
Purification and assay of microtubule-associated proteins (MAPs). Methods Enzymol (1982) 1.59
Transcription of alpha- and beta-tubulin genes in vitro in isolated Chlamydomonas reinhardi nuclei. J Cell Biol (1984) 1.57
High level expression of nonacetylatable alpha-tubulin in Chlamydomonas reinhardtii. Cell Motil Cytoskeleton (1993) 1.55
Heterogeneity of microtubule-associated protein 2 during rat brain development. Proc Natl Acad Sci U S A (1984) 1.54
Directionality and rate of assembly of chick brain tubulin onto pieces of neurotubules, flagellar axonemes, and basal bodies. Ann N Y Acad Sci (1975) 1.51
Differential localization of MAP-2 and tau in mammalian neurons in situ. Ann N Y Acad Sci (1986) 1.50
Alpha-tubulin acetylase activity in isolated Chlamydomonas flagella. J Cell Biol (1985) 1.49
Biochemical and immunological analyses of cytoskeletal domains of neurons. J Cell Biol (1986) 1.49
In vitro polymerization of tau protein monitored by laser light scattering: method and application to the study of FTDP-17 mutants. Biochemistry (2000) 1.46
An actin filament matrix in hand-isolated nuclei of X. laevis oocytes. Cell (1979) 1.44
Immunochemical and biochemical characterization of tau proteins in normal and Alzheimer's disease brains with Alz 50 and Tau-1. J Biol Chem (1988) 1.43
Immunocytochemical localization of actin and microtubule-associated protein MAP2 in dendritic spines. Proc Natl Acad Sci U S A (1983) 1.43
Assembly of flagellar radial spoke proteins in Chlamydomonas: identification of the axoneme binding domain of radial spoke protein 3. J Cell Biol (1993) 1.42
Decoration and stabilization of intact, smooth-walled microtubules with microtubule-associated proteins. Biochemistry (1979) 1.40
Multiple forms of tubulin in the cytoskeletal and flagellar microtubules of Polytomella. J Cell Biol (1981) 1.40
Localization of a kinesin-related protein to the central pair apparatus of the Chlamydomonas reinhardtii flagellum. J Cell Sci (1994) 1.36
Ligand-dependent tau filament formation: implications for Alzheimer's disease progression. Biochemistry (1999) 1.35
The ultrastructure of mouse neuroblastoma cells in tissue culture. Tissue Cell (1975) 1.33
The expression and distribution of the microtubule-associated proteins tau and microtubule-associated protein 2 in hippocampal neurons in the rat in situ and in cell culture. Neuroscience (1987) 1.32
Sequence analysis reveals homology between two proteins of the flagellar radial spoke. Mol Cell Biol (1992) 1.32
Flagellar radial spoke: a model molecular genetic system for studying organelle assembly. Cell Motil Cytoskeleton (1993) 1.31
Pigment particle translocation in detergent-permeabilized melanophores of Fundulus heteroclitus. Proc Natl Acad Sci U S A (1982) 1.30
Alzheimer disease proteins (A68) share epitopes with tau but show distinct biochemical properties. J Neurosci Res (1990) 1.28
Flagellar radial spoke protein 3 is an A-kinase anchoring protein (AKAP). J Cell Biol (2001) 1.28
Inhibition of tau polymerization by its carboxy-terminal caspase cleavage fragment. Biochemistry (2003) 1.26
Filamentous aggregates in Pick's disease, progressive supranuclear palsy, and Alzheimer's disease share antigenic determinants with microtubule-associated protein, tau. Lancet (1986) 1.25
The basal bodies of Chlamydomonas reinhardtii do not contain immunologically detectable DNA. Cell (1990) 1.23
Expression of flagellar protein genes during flagellar regeneration in Chlamydomonas. Cold Spring Harb Symp Quant Biol (1982) 1.23
Differential assembly of human tau isoforms in the presence of arachidonic acid. J Neurochem (2000) 1.23
Neuronal microtubule-associated proteins in the embryonic avian spinal cord. J Comp Neurol (1988) 1.21
A novel tau transcript in cultured human neuroblastoma cells expressing nuclear tau. J Cell Biol (1993) 1.20
Flagellar regeneration in Chlamydomonas: a model system for studying organelle assembly. Trends Cell Biol (1993) 1.16
Identification of nuclear tau isoforms in human neuroblastoma cells. Proc Natl Acad Sci U S A (1990) 1.15
Kinesin-like proteins in the flagella of Chlamydomonas. Trends Cell Biol (1994) 1.14
Tau-66: evidence for a novel tau conformation in Alzheimer's disease. J Neurochem (2001) 1.11
Polymerization of microtubule-associated protein tau under near-physiological conditions. J Biol Chem (1995) 1.10