Published in J Lab Clin Med on October 01, 1969
Geometry of normal mammalian platelets by quantitative microscopic studies. Biophys J (1976) 1.29
Electrical sizing of particles in suspensions. 3. Rigid spheroids and red blood cells. Biophys J (1972) 1.10
Adenosine diphosphate-induced aggregation of human platelets in flow through tubes. I. Measurement of concentration and size of single platelets and aggregates. Biophys J (1989) 1.10
Red cell aging in vivo. J Clin Invest (1971) 0.93
Observation of aspherical particle rotation in Poiseuille flow via the resistance pulse technique. I. Application to human erythrocytes. Biophys J (1973) 0.87
The clinical significance of positive blood cultures: a comprehensive analysis of 500 episodes of bacteremia and fungemia in adults. I. Laboratory and epidemiologic observations. Rev Infect Dis (1983) 10.03
Live attenuated malaria vaccine designed to protect through hepatic CD8⁺ T cell immunity. Science (2011) 4.72
The clinical significance of positive blood cultures: a comprehensive analysis of 500 episodes of bacteremia and fungemia in adults. II. Clinical observations, with special reference to factors influencing prognosis. Rev Infect Dis (1983) 4.52
A controlled trial of scheduled replacement of central venous and pulmonary-artery catheters. N Engl J Med (1992) 3.95
Isolation and partial characterization of a corynebacteriophage beta, tox operator constitutive-like mutant lysogen of Corynebacterium diphtheriae. J Virol (1976) 3.55
Safety and immunogenicity in man of a synthetic peptide malaria vaccine against Plasmodium falciparum sporozoites. Nature (1987) 3.51
Molecular cloning and DNA sequence analysis of a diphtheria tox iron-dependent regulatory element (dtxR) from Corynebacterium diphtheriae. Proc Natl Acad Sci U S A (1990) 3.42
Electrical counting and sizing of mammalian cells in suspension. Biophys J (1965) 3.17
Safety, infectivity, immunogenicity, and in vivo stability of two attenuated auxotrophic mutant strains of Salmonella typhi, 541Ty and 543Ty, as live oral vaccines in humans. J Clin Invest (1987) 3.03
Isolation of enterotoxin structural gene deletion mutations in Vibrio cholerae induced by two mutagenic vibriophages. Proc Natl Acad Sci U S A (1982) 2.92
Nucleotide sequence and expression of the diphtheria tox228 gene in Escherichia coli. Science (1983) 2.65
Synthesis of diphtheria tox-gene products in Escherichia coli extracts. Proc Natl Acad Sci U S A (1974) 2.62
Studies on the molecular epidemiology of diphtheria. Lancet (1983) 2.45
Characterization of an immunoglobulin binding protein homolog in the maize floury-2 endosperm mutant. Plant Cell (1991) 2.43
Evidence that the regulation of diphtheria toxin production is directed at the level of transcription. J Bacteriol (1978) 2.34
Iron, DtxR, and the regulation of diphtheria toxin expression. Mol Microbiol (1994) 2.28
Structure of the metal-ion-activated diphtheria toxin repressor/tox operator complex. Nature (1998) 2.00
Endoscopic ultrasound drainage of pancreatic pseudocyst: a prospective comparison with conventional endoscopic drainage. Endoscopy (2006) 1.90
Methods and prevalence of non-insulin-dependent diabetes mellitus in a biethnic Colorado population. The San Luis Valley Diabetes Study. Am J Epidemiol (1989) 1.86
Vertical transmission of West Nile virus by Culex and Aedes species mosquitoes. Am J Trop Med Hyg (1993) 1.86
Binding of the metalloregulatory protein DtxR to the diphtheria tox operator requires a divalent heavy metal ion and protects the palindromic sequence from DNase I digestion. J Biol Chem (1992) 1.77
Molecular epidemiological studies of United States Gulf Coast Vibrio cholerae strains: integration site of mutator vibriophage VcA-3. Infect Immun (1983) 1.76
Specific binding of the diphtheria tox regulatory element DtxR to the tox operator requires divalent heavy metal ions and a 9-base-pair interrupted palindromic sequence. Proc Natl Acad Sci U S A (1992) 1.74
Increased expression of the maize immunoglobulin binding protein homolog b-70 in three zein regulatory mutants. Plant Cell (1991) 1.70
Influence of temperature and method of centrifugation on the separation of erythrocytes. J Lab Clin Med (1973) 1.69
Alterations in the focal adhesion kinase/Src signal transduction pathway correlate with increased migratory capacity of prostate carcinoma cells. Oncogene (2001) 1.67
Restriction map of corynebacteriophages beta c and beta vir and physical localization of the diphtheria tox operon. J Bacteriol (1981) 1.67
Specific immunoglobulin A-secreting cells in peripheral blood of humans following oral immunization with a bivalent Salmonella typhi-Shigella sonnei vaccine or infection by pathogenic S. sonnei. Infect Immun (1990) 1.64
Detection of reovirus RNA in hepatobiliary tissues from patients with extrahepatic biliary atresia and choledochal cysts. Hepatology (1998) 1.64
Cloned fragment A of diphtheria toxin is expressed and secreted into the periplasmic space of Escherichia coli K12. Science (1983) 1.60
Integration of corynebacteriophages beta tox+, omega tox+, and gamma tox- into two attachment sites on the Corynebacterium diphtheriae chromosome. J Bacteriol (1983) 1.56
Precursor in cotranslational secretion of diphtheria toxin. J Bacteriol (1980) 1.54
Restriction endonuclease map of corynebacteriophage omega ctox+ isolated from the Park-Williams no. 8 strain of Corynebacterium diphtheriae. J Virol (1983) 1.52
Mechanisms of immunity in typhus infection: adoptive transfer of immunity to Rickettsia mooseri. Infect Immun (1979) 1.52
Determination of the minimal essential nucleotide sequence for diphtheria tox repressor binding by in vitro affinity selection. Proc Natl Acad Sci U S A (1994) 1.49
Characterization of the diphtheria tox transcript in Corynebacterium diphtheriae and Escherichia coli. J Bacteriol (1985) 1.49
The peritoneal environment during infection. The effect of monomicrobial and polymicrobial bacteria on pO2 and pH. Ann Surg (1991) 1.47
The influence of pH and temperature on some physical properties of normal erythrocytes and erythrocytes from patients with hereditary spherocytosis. J Lab Clin Med (1967) 1.47
Regulation of cholera toxin production in Vibrio cholerae: genetic analysis of phenotypic instability in hypertoxinogenic mutants. J Bacteriol (1980) 1.47
Fluorescence versus white-light bronchoscopy for detection of preneoplastic lesions: a randomized study. J Natl Cancer Inst (2001) 1.45
Restriction endonuclease map of the nontoxigenic corynephage gamma c and its relationship to the toxigenic corynephage beta c. J Virol (1982) 1.44
DNA sequences and characterization of dtxR alleles from Corynebacterium diphtheriae PW8(-), 1030(-), and C7hm723(-). J Bacteriol (1992) 1.44
Attenuation of virulence in Mycobacterium tuberculosis expressing a constitutively active iron repressor. Proc Natl Acad Sci U S A (1999) 1.43
Cloning and characterization of the hemolysin determinants from Vibrio cholerae RV79(Hly+), RV79(Hly-), and 569B. J Bacteriol (1985) 1.42
Predictors of functional outcome and resource utilization in inpatient rehabilitation. Arch Phys Med Rehabil (1991) 1.41
Molecular cloning of the hemolysin determinant from Vibrio cholerae El Tor. J Bacteriol (1984) 1.41
The relationship of relative risk and positive predictive value in 2 X 2 tables. Am J Epidemiol (1983) 1.40
Risk of malignancy in resected cystic tumors of the pancreas < or =3 cm in size: is it safe to observe asymptomatic patients? A multi-institutional report. J Gastrointest Surg (2007) 1.39
Low doses of interferon-alpha are as effective as higher doses in inducing remissions and prolonging survival in chronic myeloid leukemia. Ann Intern Med (1994) 1.39
Self-assembly and binding of a sorting nexin to sorting endosomes. J Cell Sci (2001) 1.38
Nucleotide sequences and comparison of the hemolysin determinants of Vibrio cholerae El Tor RV79(Hly+) and RV79(Hly-) and classical 569B(Hly-). Infect Immun (1988) 1.35
Identification of the primary metal ion-activation sites of the diphtheria tox repressor by X-ray crystallography and site-directed mutational analysis. Nat Struct Biol (1996) 1.35
A systems approach to surgical safety. Surg Endosc (2002) 1.34
Specific disruption of vimentin filament organization in monkey kidney CV-1 cells by diphtheria toxin, exotoxin A, and cycloheximide. Proc Natl Acad Sci U S A (1980) 1.33
Molecular cloning, DNA sequence analysis, and characterization of the Corynebacterium diphtheriae dtxR homolog from Brevibacterium lactofermentum. J Bacteriol (1995) 1.33
Membrane translocation of diphtheria toxin fragment A exploits early to late endosome trafficking machinery. Mol Microbiol (1997) 1.33
Complete tumor ablation with iodine 131-radiolabeled disialoganglioside GD2-specific monoclonal antibody against human neuroblastoma xenografted in nude mice. J Natl Cancer Inst (1986) 1.31
Isolation of hybridoma cell lines and characterization of monoclonal antibodies against cholera enterotoxin and its subunits. Infect Immun (1982) 1.31
Sickle cell hemoglobin (Hb AS) in black football players. JAMA (1973) 1.31
Outpatient laparoscopic cholecystectomy: patient outcomes after implementation of a clinical pathway. Ann Surg (2001) 1.28
Structures of the apo- and the metal ion-activated forms of the diphtheria tox repressor from Corynebacterium diphtheriae. Proc Natl Acad Sci U S A (1995) 1.28
Diphtheria toxin receptor binding domain substitution with interleukin-2: genetic construction and properties of a diphtheria toxin-related interleukin-2 fusion protein. Protein Eng (1987) 1.27
Isolation of nontoxinogenic mutants of Vibrio cholerae in a colorimetric assay for cholera toxin using the S49 mouse lymphosarcoma cell line. J Infect Dis (1978) 1.26
Structure/function analysis of interleukin-2-toxin (DAB486-IL-2). Fragment B sequences required for the delivery of fragment A to the cytosol of target cells. J Biol Chem (1990) 1.26
Bacteriophage conversion of heat-labile enterotoxin in Escherichia coli. J Bacteriol (1978) 1.25
Transition metal ion activation of DNA binding by the diphtheria tox repressor requires the formation of stable homodimers. Proc Natl Acad Sci U S A (1995) 1.24
Murine intranasal challenge model for the study of Campylobacter pathogenesis and immunity. Infect Immun (1996) 1.24
Interleukin 2 receptor-targeted cytotoxicity. Interleukin 2 receptor-mediated action of a diphtheria toxin-related interleukin 2 fusion protein. J Exp Med (1988) 1.23
Cysteine-102 is positioned in the metal binding activation site of the Corynebacterium diphtheriae regulatory element DtxR. Proc Natl Acad Sci U S A (1993) 1.23
The first-night effect may last more than one night. J Psychiatr Res (2001) 1.23
Genetic construction, expression, and melanoma-selective cytotoxicity of a diphtheria toxin-related alpha-melanocyte-stimulating hormone fusion protein. Proc Natl Acad Sci U S A (1986) 1.23
Epidemiology of enterotoxigenic Escherichia coli diarrhea in a pediatric cohort in a periurban area of lower Egypt. J Infect Dis (1999) 1.21
The natural history of amyotrophic lateral sclerosis. Neurology (1993) 1.21
Mechanisms of immunity in typhus infection: analysis of immunity to Rickettsia mooseri infection of guinea pigs. Infect Immun (1980) 1.20
Plaque assay for Rickettsia mooseri in tissue samples. Proc Soc Exp Biol Med (1976) 1.20
The unnecessary laparotomy for appendicitis-can it be decreased? Am Surg (1982) 1.20
Methyl groups of thymine bases are important for nucleic acid recognition by DtxR. Biochemistry (2000) 1.20
Analysis of the diphtheria tox promoter by site-directed mutagenesis. J Bacteriol (1988) 1.19
Multiple-drug-resistant Salmonella typhi. Clin Infect Dis (1993) 1.19
An investigation into the structure and bioavailability of alpha-tocopherol dispersions in Gelucire 44/14. J Control Release (2003) 1.17
Mechanisms of immunity in typhus infection: some characteristics of Rickettsia mooseri infection of guinea pigs. Infect Immun (1978) 1.16
A feasibility study of computer aided diagnosis in appendicitis. Surg Gynecol Obstet (1982) 1.14
Direct and indirect estimates of HIV-1 incidence in a high-prevalence population. Am J Epidemiol (1998) 1.14
Determination of Corynebacterium diphtheriae toxigenicity by a colorimetric tissue culture assay. J Clin Microbiol (1978) 1.13
Electrical counting and sizing of mammalian cells in suspension: an experimental evaluation. Phys Med Biol (1967) 1.10
Interleukin 2-diphtheria toxin fusion protein can abolish cell-mediated immunity in vivo. Proc Natl Acad Sci U S A (1988) 1.10
Host defenses in murine malaria: successful vaccination of mice against Plasmodium berghei by using formolized blood parasites. Am J Trop Med Hyg (1979) 1.10
Cellular processing of the interleukin-2 fusion toxin DAB486-IL-2 and efficient delivery of diphtheria fragment A to the cytosol of target cells requires Arg194. J Biol Chem (1990) 1.08
Stimulation of megakaryocytopoiesis by acute thrombocytopenia in rats. Blood (1976) 1.08
Host defenses in murine malaria: induction of a protracted state of immunity with a formalin-killed Plasmodium berghei blood parasite vaccine. Infect Immun (1978) 1.08
Monoclonal antibody analysis of diphtheria toxin--I. Localization of epitopes and neutralization of cytotoxicity. Mol Immunol (1984) 1.07
Monoclonal antibody analysis of diphtheria toxin--II. Inhibition of ADP-ribosyl-transferase activity. Mol Immunol (1984) 1.07
Host defenses in murine malaria: nonspecific resistance to Plasmodium berghei generated in response to Mycobacterium bovis infection or Corynebacterium parvum stimulation. Infect Immun (1981) 1.07
Pre-clinical toxicology of nitazoxanide--a new antiparasitic compound. J Appl Toxicol (1985) 1.07
Solution structure and peptide binding studies of the C-terminal src homology 3-like domain of the diphtheria toxin repressor protein. Proc Natl Acad Sci U S A (1999) 1.07
Mechanisms of immunity in typhus infection: some characteristics of intradermal Rickettsia mooseri infection in normal and immune guinea pigs. Infect Immun (1978) 1.06
Clinical importance of polymicrobial bacteremia. Diagn Microbiol Infect Dis (1986) 1.06
Hemoglobin CC disease: rheological properties or erythrocytes and abnormalities in cell water. J Clin Invest (1968) 1.04
Association of infiltrating lobular carcinoma with positive surgical margins after breast-conservation therapy. Ann Surg (2000) 1.04