Published in Nature on December 11, 1965
Stimulus-secretion coupling: the concept and clues from chromaffin and other cells. Br J Pharmacol (1968) 7.91
Action potentials in the rat chromaffin cell and effects of acetylcholine. J Physiol (1976) 3.54
Effects of acetylcholine and other medullary secretagogues and antagonists on the membrane potential of adrenal chromaffin cells: an analysis employing techniques of tissue culture. J Physiol (1967) 3.39
Functional and morphological characterization of isolated bovine adrenal medullary cells. J Cell Biol (1978) 2.66
The effect of veratridine on the release of catecholamines from the perfused adrenal gland. Br J Pharmacol (1979) 1.59
Colchicine inhibits adrenal medullary secretion evoked by acetylcholine without affecting that evoked by potassium. Br J Pharmacol (1972) 1.25
The reflex release of adrenaline and noradrenaline from the adrenal glands of cats and dogs. J Physiol (1980) 1.24
Effects of synthetic adrenocorticotrophin on adrenal medullary responses to splanchnic nerve stimulation in conscious calves. J Physiol (1986) 1.16
Calcium and stimulus-secretion coupling in the adrenal medulla: contrasting stimulating effects of the ionophores X-537A and A23187 on catecholamine output. J Physiol (1975) 1.15
Catecholamine secretion in a rat pheochromocytoma cell line: two pathways for calcium entry. J Physiol (1979) 1.11
Proceedings: The effects of nicotinic and muscarinic agonist drugs on the release of catecholamines from the isolated perfused adrenal glands of the dog. Br J Pharmacol (1975) 1.07
Muscarinic receptor is coupled with a cation channel through a GTP-binding protein in guinea-pig chromaffin cells. J Physiol (1991) 1.01
Acetylcholine-induced membrane depolarization and potential fluctuations in the rat adrenal chromaffin cell. J Physiol (1982) 0.94
Ca(2+)-activated K+ channels modulate muscarinic secretion in cat chromaffin cells. J Physiol (1992) 0.92
Secretory and radioligand binding studies on muscarinic receptors in bovine and feline chromaffin cells. J Physiol (1989) 0.91
Calcium channel subtypes in cat chromaffin cells. J Physiol (1994) 0.90
Ouabain distinguishes between nicotinic and muscarinic receptor-mediated catecholamine secretions in perfused adrenal glands of cat. Br J Pharmacol (1989) 0.90
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Real-time monitoring of chemical transmission in slices of the murine adrenal gland. Endocrinology (2010) 0.87
Evidence for muscarinic receptors in the adrenal medulla of the dog. Br J Pharmacol (1969) 0.87
Autonomic control of adrenal function. J Anat (1993) 0.86
Effect of muscarine on release of catecholamines from the perfused adrenal gland of the cat. Br J Pharmacol (1982) 0.86
The innervation of the mammalian adrenal gland. J Anat (1993) 0.85
Muscarinic and nicotinic mechanisms in the responses of the adrenal medulla of the dog and cat to reflex stimuli and to cholinomimetic drugs. Br J Pharmacol (1986) 0.83
Endocrine responses to intra-aortic infusions of acetylcholine in conscious calves. J Physiol (1991) 0.83
The action of guanethidine on the adrenal medulla of the cat. Br J Pharmacol Chemother (1968) 0.83
Role of calcium channels in catecholamine secretion in the rat adrenal gland. J Physiol (1999) 0.82
The source of calcium for muscarinic-mediated catecholamine release from cat adrenals. J Physiol (1992) 0.80
Paracrine role of GABA in adrenal chromaffin cells. Cell Mol Neurobiol (2010) 0.77
Blockade of desensitization of nicotinic receptors of the cat adrenal medulla by concanavalin A. Br J Pharmacol (1978) 0.77
Contribution of SK and BK channels in the control of catecholamine release by electrical stimulation of the cat adrenal gland. J Physiol (1995) 0.77
The analysis of the inhibitory effect of anaesthetics and propranolol on adreno-medullary secretion evoked by calcium or acetylcholine. Br J Pharmacol Chemother (1967) 0.77
Substance P modulates the time course of nicotinic but not muscarinic catecholamine secretion from perfused adrenal glands of rat. Br J Pharmacol (1991) 0.76
Catecholamine exocytosis during low frequency stimulation in mouse adrenal chromaffin cells is primarily asynchronous and controlled by the novel mechanism of Ca2+ syntilla suppression. J Physiol (2014) 0.76
Mechanism of action of muscarine on the longitudinal muscle of the guinea-pig isolated ileum. Br J Pharmacol (1981) 0.75
Stimulus-secretion coupling: the concept and clues from chromaffin and other cells. Br J Pharmacol (1968) 7.91
The mechanism of catecholamine release from the adrenal medulla and the role of calcium in stimulus-secretion coupling. J Physiol (1963) 6.74
Effects of acetylcholine and other medullary secretagogues and antagonists on the membrane potential of adrenal chromaffin cells: an analysis employing techniques of tissue culture. J Physiol (1967) 3.39
High short-term mortality following lung biopsy for usual interstitial pneumonia. Eur Respir J (2001) 2.67
Calcium-induced extrusion of secretory granules (exocytosis) in mast cells exposed to 48-80 or the ionophores A-23187 and X-537A. Proc Natl Acad Sci U S A (1974) 2.66
Influence of the ionic environment on the membrane potential of adrenal chromaffin cells and on the depolarizing effect of acetylcholine. J Physiol (1967) 2.48
Exocytosis (secretory granule extrusion) induced by injection of calcium into mast cells. Can J Physiol Pharmacol (1973) 2.24
Involvement of calcium in exocytosis and the exocytosis--vesiculation sequence. Biochem Soc Symp (1974) 2.23
The influence of calcium on the secretory response of the submaxillary gland to acetylcholine or to noradrenaline. J Physiol (1963) 2.20
Efflux of prostaglandin from adrenal glands stimulated with acetylcholine. Nature (1966) 2.07
Efflux of adenine nucleotides from perfused adrenal glands exposed to nicotine and other chromaffin cell stimulants. J Physiol (1965) 1.74
A possible role of microtubules in catecholamine release from the adrenal medulla: effect of colchicine, vinca alkaloids and deuterium oxide. J Pharmacol Exp Ther (1971) 1.66
On the relation between ATP splitting and secretion in the adrenal chromaffin cell: extrusion of ATP (unhydrolysed) during release of catecholamines. J Physiol (1966) 1.65
Evidence that the secreting adrenal chromaffin cell releases catecholamines directly from ATP-rich granules. J Physiol (1966) 1.63
Radiation-induced pneumonitis in the "nonirradiated" lung. Mayo Clin Proc (1999) 1.60
The role of ATP and ATPase in the release of catecholamines from the adrenal medulla. I. ATP-evoked release of catecholamines, ATP, and protein from isolated chromaffin granules. Mol Pharmacol (1967) 1.59
Organizing pneumonia. Features and prognosis of cryptogenic, secondary, and focal variants. Arch Intern Med (1997) 1.55
On the excitant effect of acetylcholine on structures in the preganglionic trunk of the cervical sympathetic: with a note on the anatomical complexities of the region. J Physiol (1960) 1.49
Action potentials occur in cells of the normal anterior pituitary gland and are stimulated by the hypophysiotropic peptide thyrotropin-releasing hormone. Proc Natl Acad Sci U S A (1977) 1.49
Antiallergic drug cromolyn may inhibit histamine secretion by regulating phosphorylation of a mast cell protein. Science (1980) 1.44
Electron microscope evidence of calcium-induced exocytosis in mast cells treated with 48-80 or the ionophores A-23187 and X-537A. J Cell Biol (1974) 1.38
Proceedings: Mast cell secretion (histamine release) induced by 48-80: calcium-dependent exocytosis inhibited strongly by cytochalasin only when glycolysis is rate-limiting. J Physiol (1973) 1.36
Effect of calcium and other ions on vasopressin release from rat neurohypophyses stimulated electrically in vitro. Nature (1965) 1.35
Histamine release by exocytosis from rat mast cells on reduction of extracellular sodium: a secretory response inhibited by calcium, strontium, barium or magnesium. J Physiol (1976) 1.30
Electrical behaviour in a line of anterior pituitary cells (GH cells) and the influence of the hypothalamic peptide, thyrotrophin releasing factor. Neuroscience (1980) 1.28
On the calcium receptor activating exocytosis: inhibitory effects of calmodulin-interacting drugs on rat mast cells. J Physiol (1982) 1.26
The need for calcium in adrenomedullary secretion evoked by biogenic amines, polypeptides, and muscarinic agents. Proc Soc Exp Biol Med (1966) 1.25
Direct stimulant effect of aminophylline on catecholamine release from the adrenal medulla. Biochem Pharmacol (1973) 1.25
Colchicine inhibits adrenal medullary secretion evoked by acetylcholine without affecting that evoked by potassium. Br J Pharmacol (1972) 1.25
The effect of amethocaine on acetylcholine-induced depolarization and catecholamine secretion in the adrenal chromaffin cell. Br J Pharmacol Chemother (1967) 1.24
Stimulus-secretion coupling: variations on the theme of calcium-activated exocytosis involving cellular and extracellular sources of calcium. Ciba Found Symp (1978) 1.24
Coated microvesicles in neuro-secretory terminals of posterior pituitary glands shed their coats to become smooth "synaptic" vesicles. Nature (1971) 1.24
Action potentials in gland cells of rat pituitary pars intermedia: inhibition by dopamine, an inhibitor of MSH secretion. J Physiol (1978) 1.20
The role of ATP and ATPase in the release of catecholamines from the adrenal medulla. II. ATP-evoked fall in optical density of isolated chromaffin granules. Mol Pharmacol (1967) 1.20
Improved oxygenation in patients with acute respiratory failure: the prone position. Am Rev Respir Dis (1977) 1.20
Calcium-dependent protein phosphorylation during secretion by exocytosis in the mast cell. Nature (1978) 1.19
The fate of the chromaffin granule during catecholamine release from the adrenal medulla. I. Unchanged efflux of phospholipid and cholesterol. Biochem Pharmacol (1967) 1.16
Calcium and stimulus-secretion coupling in the adrenal medulla: contrasting stimulating effects of the ionophores X-537A and A23187 on catecholamine output. J Physiol (1975) 1.15
The mechanism of release of catecholamines from the adrenal medulla. Pharmacol Rev (1966) 1.13
Calcium channels in rat melanotrophs are permeable to manganese, cobalt, cadmium, and lanthanum, but not to nickel: evidence provided by fluorescence changes in fura-2-loaded cells. Endocrinology (1992) 1.12
Catecholamines of supposed inhibitory hypophysiotrophic function suppress action potentials in prolactin cells. Nature (1979) 1.08
Calcium component to action potentials in rat pars intermedia cells. J Physiol (1980) 1.08
Somatostatin induces histamine secretion from rat peritoneal mast cells. Endocrinology (1978) 1.08
Thorium dioxide uptake into adrenal medullary cells and the problem of recapture of granule membrane following exocytosis. Brain Res (1972) 1.07
Microtubules and the adrenal medulla. Ann N Y Acad Sci (1975) 1.06
Somatostatin-induced histamine secretion in mast cells. Characterization of the effect. Eur J Pharmacol (1981) 1.05
GABA acts directly on cells of pituitary pars intermedia to alter hormone output. Nature (1983) 1.03
Mast cell histamine secretion in response to somatostatin analogues: structural considerations. Eur J Pharmacol (1981) 1.01
Slowing effects of dopamine and calcium-channel blockers on frequency of sodium spikes in rat pars intermedia cells. J Physiol (1982) 0.99
The fate of the chromaffin granule during catecholamine release from the adrenal medulla. 3. Recovery of a purified fraction of electron-translucent structures. Biochem Pharmacol (1968) 0.99
High-resolution CT of the lungs: findings in various pulmonary diseases. AJR Am J Roentgenol (1992) 0.98
The role of adenosine triphosphate and adenosine triphosphatase in the release of catecholamines from the adrenal medulla. IV. Adenosine triphosphate-- activated uptake of calcium by microsomes and mitochondria. Mol Pharmacol (1970) 0.97
Ultrastructural evidence of secretion by exocytosis and of "synaptic vesicle" formation in posterior pituitary glands. Nature (1970) 0.97
The effect of metabolic inhibitors on the release of vasopressin from the isolated neurohypophysis. J Physiol (1965) 0.97
A possible mechanism of release of posterior pituitary hormones involving adenosine triphosphate and an adenosine triphosphatase in the neurosecretory granules. Mol Pharmacol (1968) 0.96
Methemoglobinemia induced by a topical anesthetic spray (cetacaine). Chest (1977) 0.95
The stimulant effect of cold on vasopressin release from the neurohypophysis in vitro. J Physiol (1965) 0.94
Differential inhibitory effects of the arachidonic acid analog ETYA on rat mast cell exocytosis evoked by secretagogues utilizing cellular or extracellular calcium. Eur J Pharmacol (1980) 0.94
The fate of the chromaffin granule during catecholamine release from the adrenal medulla. II. Loss of protein and retention of lipid in subcellular fractions. Biochem Pharmacol (1967) 0.93
GABA directly affects electrophysiological properties of pituitary pars intermedia cells. Nature (1982) 0.93
Localization of renin in trophoblasts in human chorion laeve at term pregnancy. Endocrinology (1981) 0.93
Effects of veratridine, tetrodotoxin and other drugs that alter electrical behaviour on secretion of melanocyte-stimulating hormone from melanotrophs of the pituitary pars intermedia. Neuroscience (1984) 0.92
Vasopressin release from the isolated neurohypophysis induced by a calcium ionophore, X-537A. Nature (1974) 0.92
Potassium-induced secretion of melanocyte-stimulating hormone from isolated pars intermedia cells signals participation of voltage-dependent calcium channels in stimulus-secretion coupling. Neuroscience (1981) 0.92
Caffeine-induced catecholamine secretion: similarity to caffeine-induced muscle contraction. Proc Soc Exp Biol Med (1973) 0.91
Risk of anesthesia and surgery in patients with chronic bronchitis and chronic obstructive pulmonary disease. Surgery (1973) 0.91
Effects of cytochalasin B and colchicine on secretion of posterior pituitary and adrenal medullary hormones. Br J Pharmacol (1972) 0.91
Aspects of the calcium hypothesis of stimulus-secretion coupling: electrical activity in adenohypophyseal cells, and membrane retrieval after exocytosis. Methods Cell Biol (1981) 0.91
Secretion in mast cells induced by calcium entrapped within phospholipid vesicles. Science (1978) 0.91
Release of catecholamines from isolated adrenal chromaffin granules by endogenous ATP. Mol Pharmacol (1968) 0.89
Congestive heart failure, hypertension, and hyperreninemia in bilateral Wilms' tumor: successful medical management. Med Pediatr Oncol (1986) 0.88
Role of bronchoalveolar lavage in the assessment of opportunistic pulmonary infections: utility and complications. Mayo Clin Proc (1987) 0.86
Secretagogue effect of barium on output of melanocyte-stimulating hormone from pars intermedia of the mouse pituitary. J Physiol (1983) 0.86
Short and long term regulation of catecholamine biosynthetic enzymes by angiotensin in cultured adrenal medullary cells. Molecular mechanisms and nature of second messenger systems. J Biol Chem (1990) 0.86
Direct stimulation of renin release by calcium. Proc Soc Exp Biol Med (1976) 0.86
Pharmacological and ionic features of gamma-aminobutyric acid receptors influencing electrical properties of melanotrophs isolated from the rat pars intermedia. Neuroscience (1985) 0.85
Effects of microfilament-active drugs, phalloidin and the cytochalasins A and B, on exocytosis in mast cells evoked by 48/80 or A23187. Naunyn Schmiedebergs Arch Pharmacol (1978) 0.84
Adenosine triphosphate and adenosine triphosphatase in hormone-containing granules of posterior pituitary gland. Science (1968) 0.84
The role of adenosine triphosphate and adenosine triphosphatase in the release of catecholamines from the adrenal medulla. 3. Similarities between the effects of adenosine triphosphate on chromaffin granules and on mitochondria. Mol Pharmacol (1969) 0.84
Cytosolic Ca2+ in melanotrophs: pharmacological insights into regulatory influences of electrical activity and ion channels. Endocrinology (1990) 0.84
Pulmonary venoocclusive disease: CT findings in eight patients. AJR Am J Roentgenol (1996) 0.83
Inactivation of amniotic prorenin by ethyl diazoacetylglycinate. Biochem Biophys Res Commun (1980) 0.83
Membrane vesiculation at sites of exocytosis in the neurohypophysis, adenohypophysis and adrenal medulla: a device for membrane conservation. J Physiol (1971) 0.83
Depolarizing effects of the ionophores X-537A and A23187 and their relevance to secretion. Br J Pharmacol (1975) 0.83
Estrogens act in rat hippocampus and frontal cortex to produce rapid, receptor-mediated decreases in serotonin 5-HT(1A) receptor function. Neuroendocrinology (2001) 0.83
Spontaneous cytosolic calcium pulsing detected in Xenopus melanotrophs: modulation by secreto-inhibitory and stimulant ligands. Endocrinology (1993) 0.82
Stimulation of adrenal medullary cells in vivo and in vitro induces expression of c-fos proto-oncogene. Oncogene (1990) 0.81