Erythrocytic nucleoside diphosphokinase. II. Isolation and kinetics.

PubWeight™: 1.03‹?› | Rank: Top 15%

🔗 View Article (PMID 5903722)

Published in J Biol Chem on January 25, 1966

Authors

N Mourad, R E Parks

Articles by these authors

Tight-binding inhibitors--IV. Inhibition of adenosine deaminases by various inhibitors. Biochem Pharmacol (1977) 2.13

Purine Metabolism in Tetrahymena and Its Relation to Malignant Cells in Mice. Science (1949) 1.83

Guanylate kinases from human erythrocytes, hog brain, and rat liver. Methods Enzymol (1978) 1.60

Three-dimensional structure of human erythrocytic purine nucleoside phosphorylase at 3.2 A resolution. J Biol Chem (1990) 1.46

Squamous neoplasms of the stomach. Am J Roentgenol Radium Ther Nucl Med (1967) 1.36

Adenosine deaminase from human erythrocytes: purification and effects of adenosine analogs. Biochem Pharmacol (1975) 1.33

Purine nucleoside phosphorylase from human erythrocytes. IV. Crystallization and some properties. J Biol Chem (1969) 1.31

Tight-binding inhibitors-II. Non-steady state nature of inhibition of milk xanthine oxidase by allopurinol and alloxanthine and of human erythrocytic adenosine deaminase by coformycin. Biochem Pharmacol (1975) 1.27

Purine nucleoside phosphorylase. Microheterogeneity and comparison of kinetic behavior of the enzyme from several tissues and species. Biochemistry (1975) 1.25

Purine nucleoside phosphorylase from human erythroyctes. II. Kinetic analysis and substrate-binding studies. J Biol Chem (1968) 1.22

Purine nucleoside phosphorylase from human erythrocytes. I. Purification and properties. J Biol Chem (1968) 1.19

Human erythrocytic purine nucleoside phosphorylase: reaction with sugar-modified nucleoside substrates. Biochemistry (1980) 1.17

Nucleoside diphosphokinase from human erythrocytes. Methods Enzymol (1978) 1.17

Morphological analysis of circulating tumour cells in patients undergoing surgery for non-small cell lung carcinoma using the isolation by size of epithelial tumour cell (ISET) method. Cytopathology (2011) 1.16

Potent inhibition of muscle 5'-AMP deaminase by the nucleoside antibiotics coformycin and deoxycoformycin. Biochem Pharmacol (1977) 1.13

Incorporation of analog purine nucleosides into the formed elements of human blood: erythrocytes, platelets, and lymphocytes. Ann N Y Acad Sci (1975) 1.13

Purine nucleoside phosphorylase. 3. Reversal of purine base specificity by site-directed mutagenesis. Biochemistry (1997) 1.05

Purine nucleoside metabolism in the erythrocytes of patients with adenosine deaminase deficiency and severe combined immunodeficiency. J Clin Invest (1976) 1.03

Inhibitors of purine nucleoside phosphorylase, C(8) and C(5') substitutions. Biochem Pharmacol (1982) 1.03

Purine nucleoside phosphorylase from human erythrocytes. 3. Inhibition by the inosine analog formycin B of the isolated enzyme and of nucleoside metabolism in intact erythrocytes and sarcoma 180 cells. Mol Pharmacol (1968) 1.02

Experience with Hemophilus influenzae pneumonia. Radiology (1966) 1.00

Substrate specificities of 5'-deoxy-5'-methylthioadenosine phosphorylase from Trypanosoma brucei brucei and mammalian cells. Mol Biochem Parasitol (1988) 0.98

Adenosine deaminase from human erythrocytes. Methods Enzymol (1978) 0.97

5'-Methylthioadenosine phosphorylase-L. Substrate activity of 5'-deoxyadenosine with the enzyme from Sarcoma 180 cells. Biochem Pharmacol (1981) 0.96

Forskolin: a potential antimetastatic agent. Int J Cancer (1983) 0.95

Purine metabolism in primitive erythrocytes. Comp Biochem Physiol B (1973) 0.95

Erythrocytic nucleoside diphosphokinase. 3. Studies with free and phosphorylated enzyme and evidence for an essential thiol group. J Biol Chem (1966) 0.94

Purine nucleoside phosphorylase from human erythrocytes. Methods Enzymol (1978) 0.94

Nucleotide profiles of the formed elements of human blood determined by high-pressure liquid chromatography. Blood (1973) 0.93

A simple method for obtaining platelet concentrates free of aggregates. Transfusion (1968) 0.90

Purine nucleoside phosphorylase from human erythrocytes: physiocochemical properties of the crystalline enzyme. Biochemistry (1978) 0.90

An hypothesis on the mechanism of action of 6-thioguanine. Biochem Pharmacol (1967) 0.89

Changes in nucleoside transport of HL-60 human promyelocytic cells during N,N-dimethylformamide induced differentiation. Cancer Res (1986) 0.88

Characterization of a defect in the pathway for converting 5'-deoxy-5'-methylthioadenosine to methionine in a subline of a cultured heterogeneous human colon carcinoma. J Biol Chem (1984) 0.88

Reaction of 5'-deoxyadenosine and related analogs with the 5'-methylthioadenosine cleaving enzyme of sarcoma 180 cells, a possible chemotherapeutic target enzyme. Biochem Pharmacol (1979) 0.87

Incorporation of nucleosides into the nucleotide pools of human erythrocytes. Adenosine and its analogs. Biochemistry (1973) 0.87

Design of purine nucleoside phosphorylase inhibitors. Fed Proc (1986) 0.86

Tight binding inhibitors--VIII. Studies of the interactions of 2'-deoxycoformycin and transport inhibitors with the erythrocytic nucleoside transport system. Biochem Pharmacol (1980) 0.86

Succinic thiokinase. V. Preparation of labeled substrates, their bindings to the enzyme, and isotope exchange studies. J Biol Chem (1967) 0.85

Erythrocytic nucleoside diphosphokinase. V. Some properties and behavior of the pI 7.3 isozyme. J Biol Chem (1971) 0.83

The interaction of the nucleoside analogues, formycins A and B, with xanthine oxidase and hepatic aldehyde oxidase. Mol Pharmacol (1970) 0.83

HLA-DR antigens and phenotypes in Dutch coeliac children and their families. Clin Genet (1985) 0.83

Identification and isolation on a large scale of guanylate kinase from human erythrocytes. Effects of monophosphate nucleotides of purine analogs. Biochem Pharmacol (1971) 0.83

Inhibitors of purine nucleoside phosphorylase: effects of 9-deazapurine ribonucleosides and synthesis of 5'-deoxy-5'-iodo-9-deazainosine. Cancer Res (1986) 0.82

Purine nucleoside phosphorylase from human erythrocytes. V. Content and behavior of sulfhydryl groups. J Biol Chem (1971) 0.82

Demonstration of the heterogeneity of nucleoside diphosphokinase in rat tissues. Biochemistry (1973) 0.82

Succinic thiokinase. IV. Improved method of purification, arsenolysis of guanosine triphosphate, succinate-dependent guanosine triphos- phatase activity, and some other properties of the enzyme. J Biol Chem (1967) 0.82

Adenosine metabolism in human whole blood. Effects of nucleoside transport inhibitors and phosphate concentration. Biochem Pharmacol (1988) 0.82

Adenosine triphosphate-guanosine 5'-phosphate phosphotransferase. IV. Isozymes in human erythrocytes and Sarcoma 180 ascites cells. Mol Pharmacol (1972) 0.82

Effect of chirality in erythro-9-(2-hydroxy-3-nonyl) adenine (EHNA) on adenosine deaminase inhibition. Biochem Pharmacol (1982) 0.82

Plasma adenosine deaminase2: a marker for human immunodeficiency virus infection. J Acquir Immune Defic Syndr (1991) 0.82

Role of adenosine uptake and metabolism by blood cells in the antiplatelet actions of dipyridamole, dilazep and nitrobenzylthioinosine. Biochem Pharmacol (1985) 0.81

N-Methylformycins. Reactivity with adenosine deaminase, incorporation into intracellular nucleotides of human erythrocytes and L 1210 cells and cytotoxicity to L 1210 cells. Biochem Pharmacol (1979) 0.81

Adenosine analogs and human platelets. Effects on nucleotide pools and the aggregation phenomenon. Biochem Pharmacol (1975) 0.81

Adenosine analogs and human platelets--II. Inhibition of ADP-induced aggregation by carbocyclic adenosine and imidazole-ring modified analogs. Significance of alterations in the nucleotide pools. Biochem Pharmacol (1979) 0.81

Erythrocytic nucleoside diphosphokinase. IV. Evidence for electrophoretic heterogeneity. Biochemistry (1971) 0.81

Pathways of nucleotide metabolism in Schistosoma mansoni. IV. Incorporation of adenosine analogs in vitro. Biochem Pharmacol (1973) 0.81

Liver shunts. Am J Roentgenol Radium Ther Nucl Med (1968) 0.81

5'-deoxy-5'-methylthioadenosine phosphorylase--IV. Biological activity of 2-fluoroadenine-substituted 5'-deoxy-5'-methylthioadenosine analogs. Biochem Pharmacol (1987) 0.81

Platelet-activating factor (PAF)-induced platelet aggregation. Modulation by plasma adenosine and methylxanthines. Biochem Pharmacol (1994) 0.80

N,N-dimethylformamide and sodium butyrate modulation of the activities of purine-metabolizing enzymes in cultured human colon carcinoma cells. Cancer Res (1981) 0.80

Role of nucleoside transport in drug action. The adenosine deaminase inhibitor, deoxycoformycin, and the antiplatelet drugs, dipyridamole and dilazep. Ann N Y Acad Sci (1985) 0.80

A possible association between the nucleoside transport system of human erythrocytes and adenosine deaminase. Biochem Pharmacol (1975) 0.80

Tight binding inhibitors--VI. Interactions of deoxycoformycin and adenosine deaminase in intact human erythrocytes and sarcoma 180 cells. Biochem Pharmacol (1978) 0.80

Double-blind study of four oral cholecystographic preparations. Radiology (1974) 0.80

Pathways of nucleotide metabolism in Schistosoma mansoni. 3. Identification of enzymes in cell-free extracts. Biochem Pharmacol (1973) 0.80

Activities of purine-metabolizing enzymes in human colon carcinoma cell lines and xenograft tumors. Biochem Pharmacol (1981) 0.79

Differential incorporation of 2'-deoxyadenosine into human peripheral lymphocytes. Biochem Pharmacol (1985) 0.79

Mechanism of activation of triciribine phosphate (TCN-P) as a prodrug form of TCN. Cancer Treat Rep (1986) 0.79

Conversion of 5'-deoxy-5'-methylthioadenosine and 5'-deoxy-5'-methylthioinosine to methionine in cultured human leukemic cells. Cancer Res (1983) 0.79

Potentiation of the antiplatelet action of adenosine in whole blood by dipyridamole or dilazep and the cAMP phosphodiesterase inhibitor, RA 233. Thromb Res (1986) 0.79

5'-Deoxy-5'-methylthioadenosine phosphorylase--III. Role of the enzyme in the metabolism and action of 5'-halogenated adenosine analogs. Biochem Pharmacol (1985) 0.79

Inhibition of human purine nucleoside phosphorylase by acyclic nucleosides and nucleotides. Biochem Pharmacol (1987) 0.78

Effects of adenosine analogs and adenine nucleotides on adenosine 5'-diphosphate-induced rat platelet aggregation. Biochem Pharmacol (1980) 0.78

Cyclosporine lymphocyte maximum level monitoring in de novo kidney transplant patients: a prospective study. Exp Clin Transplant (2006) 0.78

An enzymatic method to determine damage in human platelets. Proc Soc Exp Biol Med (1967) 0.78

Succinic thiokinase. 3. The occurrence of a nonphosphorylated high energy intermediate of the enzyme. J Biol Chem (1965) 0.78

Crystallization and preliminary X-ray investigation of human erythrocytic purine nucleoside phosphorylase. J Biol Chem (1981) 0.78

5'-Methylthioadenosine and 2',5'-dideoxyadenosine blockade of the inhibitory effects of adenosine on ADP-induced platelet aggregation by different mechanisms. Biochem Pharmacol (1980) 0.77

Biochemical mechanisms for the synergism between 6-thioguanine and 6-(methylmercapto)purine ribonucleoside in sarcoma 180 cells. Cancer Res (1972) 0.77

Adenosine deaminase inhibitors. Conversion of a single chiral synthon into erythro- and threo-9-(2-hydroxy-3-nonyl)adenines. J Med Chem (1981) 0.77

Synthesis and biological evaluation of 6-amino-1H-pyrrolo[3,2-c]pyridin-4(5H)-one (3,7-dideazaguanine). J Med Chem (1984) 0.77

Nucleotidase activities of human peripheral lymphocytes. Biochem Pharmacol (1985) 0.77

Use of high-pressure liquid chromatography for monitoring nucleotide concentration in human blood: a preliminary study with stored blood cell suspensions. Clin Chem (1973) 0.77

5-Iodoribose 1-phosphate, an analog of ribose 1-phosphate. Enzymatic synthesis and kinetic studies with enzymes of purine, pyrimidine, and sugar phosphate metabolism. J Biol Chem (1986) 0.76

Inhibition of purine nucleoside phosphorylase by 9-(phosphonoalkyl)hypoxanthines. Biochem Pharmacol (1986) 0.76

5'-deoxy-5'-methylthioadenosine phosphorylase--II. Role of the enzyme in the metabolism and antineoplastic action of adenine-substituted analogs of 5'-deoxy-5'-methylthioadenosine. Biochem Pharmacol (1983) 0.76

Effects of the chiral isomers of erythro- and threo-9-(2-hydroxy-3-nonyl)adenine on purine metabolism in sarcoma 180 cells. Biochem Pharmacol (1982) 0.76

Transport of deoxycoformycin in human erythrocytes. Measurement by adenosine deaminase titration and radioisotope assays. Biochem Pharmacol (1984) 0.76

Nucleotide metabolism in the whole blood of various vertebrates: enzyme levels and the use of high pressure liquid chromatography for the determination of nucleotide patterns. Comp Biochem Physiol B (1972) 0.76

Adenosine triphosphate-guanosine 5'-phosphate phosphotransferase. II. Inhibition by 6-thioguanosine 5'-phosphate of the enzyme isolated from hog brain and sarcoma 180 ascites cells. Mol Pharmacol (1969) 0.76

Potentiation of 5-Fluorouracil Inhibition of Flexner-Jobling Carcinoma by Glucose. Science (1963) 0.76

Crystallization of human liver alcohol dehydrogenase. Arch Biochem Biophys (1967) 0.76

Incorporation of purine analogs into the nucleotide pools of human erythrocytes. Adv Exp Med Biol (1973) 0.76

Effect of prolonged storage on erythrocyte enzymes. Transfusion (1969) 0.75

Cyclosporine lymphocyte level and lymphocyte count: new guidelines for tailoring immunosuppressive therapy. Transplant Proc (2003) 0.75

Chong M. Kong: Recollections. R I Med J (1975) 0.75

Inhibition of rat hepatic guanylate kinase by 6-thioguanosine-5'-phosphate and 6-selenoguanosine-5'-phosphate. Biochem Pharmacol (1975) 0.75

The use of high pressure liquid chromatography to monitor nucleotide levels in cells. Adv Exp Med Biol (1974) 0.75