Published in Gene on December 01, 1984
Cloning and expression of a Streptomyces cholesterol oxidase gene in Streptomyces lividans with plasmid pIJ702. Appl Environ Microbiol (1986) 1.14
Streptomyces cloning: useful recombinant DNA systems and a summation of cloned genes. Antimicrob Agents Chemother (1988) 0.95
A 5' untranslated region which directs accurate and robust translation by prokaryotic and mammalian ribosomes. Nucleic Acids Res (1996) 0.92
Increased expression in Escherichia coli of a synthetic gene encoding human somatomedin C after gene duplication and fusion. J Bacteriol (1987) 0.81
Secretion of interleukin-1 beta and Escherichia coli galactokinase by Streptomyces lividans. J Bacteriol (1988) 0.77
Preparation and characterization of bovine growth hormones produced in recombinant Escherichia coli. Biochem J (1987) 0.75
The Functional Assessment of Cancer Therapy scale: development and validation of the general measure. J Clin Oncol (1993) 18.75
Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits. Nature (1994) 9.76
The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7). Science (1996) 7.10
Fluorescence microscopy in three dimensions. Methods Cell Biol (1989) 6.70
Cloning and expression of the tyrosinase gene from Streptomyces antibioticus in Streptomyces lividans. J Gen Microbiol (1983) 6.44
A new class of ligand-gated ion channel defined by P2x receptor for extracellular ATP. Nature (1994) 5.43
Coexpression of P2X2 and P2X3 receptor subunits can account for ATP-gated currents in sensory neurons. Nature (1995) 5.38
pIJ101, a multi-copy broad host-range Streptomyces plasmid: functional analysis and development of DNA cloning vectors. Mol Gen Genet (1982) 5.02
Inhibition of ColE1 RNA primer formation by a plasmid-specified small RNA. Proc Natl Acad Sci U S A (1981) 4.14
Diffuse axonal injury and traumatic coma in the primate. Ann Neurol (1982) 4.08
Gene cloning in Streptomyces. Curr Top Microbiol Immunol (1982) 3.95
Nitric oxide synthase is not a constituent of the antimicrobial armature of human mononuclear phagocytes. J Infect Dis (1993) 3.75
Cloning OF P2X5 and P2X6 receptors and the distribution and properties of an extended family of ATP-gated ion channels. J Neurosci (1996) 3.71
Decreased levels of the cell-cycle inhibitor p27Kip1 protein: prognostic implications in primary breast cancer. Nat Med (1997) 3.57
DNA cloning in Streptomyces: resistance genes from antibiotic-producing species. Nature (1980) 3.36
Persistence of nevirapine-resistant HIV-1 in women after single-dose nevirapine therapy for prevention of maternal-to-fetal HIV-1 transmission. Proc Natl Acad Sci U S A (2006) 3.26
The origin of replication of plasmid p15A and comparative studies on the nucleotide sequences around the origin of related plasmids. Cell (1983) 3.18
Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse. J Exp Med (1995) 3.18
Cloning of antibiotic resistance and nutritional genes in streptomycetes. J Bacteriol (1982) 3.06
Nucleotide sequence of a streptomycete aminoglycoside phosphotransferase gene and its relationship to phosphotransferases encoded by resistance plasmids. Proc Natl Acad Sci U S A (1983) 2.87
Reduced vas deferens contraction and male infertility in mice lacking P2X1 receptors. Nature (2000) 2.85
Physical analysis of antibiotic-resistance genes from Streptomyces and their use in vector construction. Gene (1982) 2.81
Prevention of vertical transmission of HIV: analysis of cost effectiveness of options available in South Africa. BMJ (1999) 2.79
Human T-cell clonal anergy is induced by antigen presentation in the absence of B7 costimulation. Proc Natl Acad Sci U S A (1993) 2.76
Pharmacological characterization of heterologously expressed ATP-gated cation channels (P2x purinoceptors). Mol Pharmacol (1995) 2.50
Metabolic differentiation of distinct muscle types at the level of enzymatic organization. Eur J Biochem (1969) 2.49
The separation, identification and estimation of prostaglandins in nanogram quantities by combined gas chromatography-mass spectrometry. Life Sci I (1970) 2.42
The short Synacthen and insulin stress tests in the assessment of the hypothalamic-pituitary-adrenal axis. Clin Endocrinol (Oxf) (1996) 2.41
Genetic identification of cloned fragments of bacteriophage T4 DNA and complementation by some clones containing early T4 genes. Mol Gen Genet (1977) 2.27
Comparison of PCR, culture, and direct fluorescent-antibody testing for detection of Bordetella pertussis. J Clin Microbiol (1999) 2.26
Identification of BTG2, an antiproliferative p53-dependent component of the DNA damage cellular response pathway. Nat Genet (1996) 2.26
Hyponatraemia. Clin Endocrinol (Oxf) (2000) 2.13
Effect of orally administered prostaglandin E1 on gastric secretion and gastrointestinal motility in man. Gut (1968) 2.09
Results of preliminary clinical trials of the positron emission mammography system PEM-I: a dedicated breast imaging system producing glucose metabolic images using FDG. J Nucl Med (2000) 2.09
Ionic permeability of, and divalent cation effects on, two ATP-gated cation channels (P2X receptors) expressed in mammalian cells. J Physiol (1996) 2.07
P2X receptors bring new structure to ligand-gated ion channels. Trends Neurosci (1995) 2.05
The Notch ligand, Jagged-1, influences the development of primitive hematopoietic precursor cells. Blood (1998) 2.05
Activated human B lymphocytes express three CTLA-4 counterreceptors that costimulate T-cell activation. Proc Natl Acad Sci U S A (1993) 2.03
The relationship between HAART use and sexual activity among HIV-positive women of reproductive age in Brazil, South Africa, and Uganda. AIDS Care (2008) 2.03
A novel approach to providing children's dentistry in general dental practice. Br Dent J (1997) 2.02
Identification of amino acid residues contributing to the pore of a P2X receptor. EMBO J (1997) 2.02
Measuring empathy: reliability and validity of the Empathy Quotient. Psychol Med (2004) 1.99
Evaluation of the associations between carotid artery atherosclerosis and coronary artery stenosis. A case-control study. Circulation (1990) 1.99
Inaccuracies in measurement of dried milk powders. Br Med J (1973) 1.99
Streptogramin-based gene regulation systems for mammalian cells. Nat Biotechnol (2000) 1.98
Immunohistochemical study of the P2X2 and P2X3 receptor subunits in rat and monkey sensory neurons and their central terminals. Neuropharmacology (1997) 1.96
Mutations in the principal neutralization determinant of human immunodeficiency virus type 1 affect syncytium formation, virus infectivity, growth kinetics, and neutralization. J Virol (1992) 1.94
Benign small bowel tumor. Ann Surg (1975) 1.92
Tissue distribution of the P2X7 receptor. Neuropharmacology (1997) 1.90
Optimal resection margin for cutaneous malignant melanoma. Plast Reconstr Surg (1983) 1.89
Cocaine use during pregnancy: adverse perinatal outcome. Am J Obstet Gynecol (1987) 1.88
Initiation of DNA synthesis in Escherichia coli. Annu Rev Biochem (1979) 1.88
Hereditary spastic paraparesis: a review of new developments. J Neurol Neurosurg Psychiatry (2000) 1.87
Differential distribution of two ATP-gated channels (P2X receptors) determined by immunocytochemistry. Proc Natl Acad Sci U S A (1996) 1.86
Transcranial magnetic stimulation during positron emission tomography: a new method for studying connectivity of the human cerebral cortex. J Neurosci (1997) 1.85
P2X3 is expressed by DRG neurons that terminate in inner lamina II. Eur J Neurosci (1998) 1.85
Annotated draft genomic sequence from a Streptococcus pneumoniae type 19F clinical isolate. Microb Drug Resist (2001) 1.82
Scavenger receptors, oxidized LDL, and atherosclerosis. Ann N Y Acad Sci (2001) 1.82
New method of serotyping Escherichia coli: implementation and verification. J Clin Microbiol (1987) 1.77
KOJAK encodes a cellulose synthase-like protein required for root hair cell morphogenesis in Arabidopsis. Genes Dev (2001) 1.77
Contribution of individual subunits to the multimeric P2X(2) receptor: estimates based on methanethiosulfonate block at T336C. Mol Pharmacol (1999) 1.70
Biochemical characterization of resistance determinants cloned from antibiotic-producing streptomycetes. J Bacteriol (1982) 1.70
Thiostrepton-induced gene expression in Streptomyces lividans. J Bacteriol (1989) 1.65
B7 but not intercellular adhesion molecule-1 costimulation prevents the induction of human alloantigen-specific tolerance. J Exp Med (1993) 1.63
Changes in the demographics and perioperative care of stage IA(2)/IB(1) cervical cancer over the past 16 years. Gynecol Oncol (2001) 1.61
Differential up-regulation of the B7-1 and B7-2 costimulatory molecules after Ig receptor engagement by antigen. J Immunol (1994) 1.61
One year's work at a centre for the treatment of addicted patients. Lancet (1968) 1.59
Autogenous transcriptional activation of a thiostrepton-induced gene in Streptomyces lividans. EMBO J (1993) 1.59
Optimizing the expression in E. coli of a synthetic gene encoding somatomedin-C (IGF-I). Nucleic Acids Res (1985) 1.56
Dissecting the centromere of the human Y chromosome with cloned telomeric DNA. Hum Mol Genet (1994) 1.56
Population pharmacokinetics of tenofovir in HIV-1-infected pregnant women and their neonates (ANRS 12109). Clin Pharmacol Ther (2008) 1.56
Carcinoma arising in pilonidal sinuses. Ann Surg (1981) 1.54
Loss of imprinting and cancer. J Pathol (2007) 1.52
Local injection of the 90Y-labelled peptidic vector DOTATOC to control gliomas of WHO grades II and III: an extended pilot study. Eur J Nucl Med Mol Imaging (2002) 1.50
POLG mutations in Alpers syndrome. Neurology (2005) 1.49
Properties of the DNA-delay mutants of bacteriophage T4. Virology (1971) 1.49
Increased proliferation rate of lymphoid cells transfected with the P2X(7) ATP receptor. J Biol Chem (1999) 1.48
ATP-mediated cytotoxicity in microglial cells. Neuropharmacology (1997) 1.48
High-level secretion of human growth hormone by Escherichia coli. Gene (1987) 1.47
Methylation silencing and mutations of the p14ARF and p16INK4a genes in colon cancer. Lab Invest (2001) 1.46
Hyponatremia following mild/moderate subarachnoid hemorrhage is due to SIAD and glucocorticoid deficiency and not cerebral salt wasting. J Clin Endocrinol Metab (2013) 1.46
Senile breakdown in standards of personal and environmental cleanliness. Br Med J (1966) 1.45
Construction of thiostrepton-inducible, high-copy-number expression vectors for use in Streptomyces spp. Gene (1995) 1.44
Homologous chromosome pairing in wheat. J Cell Sci (1999) 1.43
Construction and properties of recombinant plasmids containing the rII genes of bacteriophage T4. Mol Gen Genet (1978) 1.43
Subacute pulmonary granulomatous schistosomiasis: high resolution CT appearances--another cause of the halo sign. Br J Radiol (2001) 1.43
Dose-dependent reduction of cerebral blood flow during rapid-rate transcranial magnetic stimulation of the human sensorimotor cortex. J Neurophysiol (1998) 1.42
Motion correction of PET images using multiple acquisition frames. IEEE Trans Med Imaging (1997) 1.42
Construction of a series of pSAM2-based integrative vectors for use in actinomycetes. Gene (1990) 1.41
Acetylcholinesterase knockouts establish central cholinergic pathways and can use butyrylcholinesterase to hydrolyze acetylcholine. Neuroscience (2002) 1.41
Is there a difference in the efficacy of peripartum antiretroviral regimens in reducing mother-to-child transmission of HIV in Africa? AIDS (2005) 1.41
Identical triplets in a thoroughbred mare. Equine Vet J (1995) 1.39
Molecular characterisation of plant U14 small nucleolar RNA genes: closely linked genes are transcribed as polycistronic U14 transcripts. Nucleic Acids Res (1994) 1.38
Evolution of the glutamine synthetase gene, one of the oldest existing and functioning genes. Proc Natl Acad Sci U S A (1993) 1.38
The molecular basis of medium-chain acyl-CoA dehydrogenase (MCAD) deficiency in compound heterozygous patients: is there correlation between genotype and phenotype? Hum Mol Genet (1997) 1.36
Methylation involved in chemotaxis is regulated during Caulobacter differentiation. Proc Natl Acad Sci U S A (1983) 1.36
Detection of Bordetella holmesii using Bordetella pertussis IS481 PCR assay. J Clin Microbiol (2000) 1.36
How well do physicians recognize melanoma and other problem lesions? J Am Acad Dermatol (1986) 1.34