Published in J Pharm Pharmacol on November 01, 1983
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Flow-dependent, endothelium-mediated dilation of epicardial coronary arteries in conscious dogs: effects of cyclooxygenase inhibition. J Cardiovasc Pharmacol (1985) 1.62
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A simple and sensitive bioassay method for detection of EDRF with RFL-6 rat lung fibroblasts. Am J Physiol (1991) 1.47
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Colocalization of nitric oxide synthase and NADPH-diaphorase in the myenteric plexus of the rat gut. Neurosci Lett (1992) 1.40
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The role of prostaglandins in the endothelium-mediated vasodilatory response to hypoxia. Pflugers Arch (1984) 1.39
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The endothelium-dependent vasodilator effect of acetylcholine: characterization of the endothelial relaxing factor with inhibitors of arachidonic acid metabolism. Eur J Pharmacol (1984) 1.37
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Human cationic amino acid transporters hCAT-1, hCAT-2A, and hCAT-2B: three related carriers with distinct transport properties. Biochemistry (1997) 1.33
Characterization and localization of endothelial nitric oxide synthase using specific monoclonal antibodies. Am J Physiol (1993) 1.29
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Characterization of nitric oxide synthases in non-adrenergic non-cholinergic nerve containing tissue from the rat anococcygeus muscle. Br J Pharmacol (1991) 1.25
A correlation between soluble brain nitric oxide synthase and NADPH-diaphorase activity is only seen after exposure of the tissue to fixative. Neurosci Lett (1993) 1.25
Glucocorticoids inhibit the induction of nitric oxide synthase II by down-regulating cytokine-induced activity of transcription factor nuclear factor-kappa B. Mol Pharmacol (1996) 1.21
Nitric oxide synthase immunoreactivity in the rat, mouse, cat and squirrel monkey spinal cord. Neuroscience (1993) 1.18
Species-dependent differences in the nature of endothelium-derived vascular relaxing factor. Eur J Pharmacol (1984) 1.17
Estrogens increase transcription of the human endothelial NO synthase gene: analysis of the transcription factors involved. Hypertension (1998) 1.14
Subcellular localization and characterization of nitric oxide synthase(s) in endothelial cells: physiological implications. Biochem J (1994) 1.14
The importance of endogenous prostaglandins other than prostacyclin, for the modulation of contractility of some rabbit blood vessels. Br J Pharmacol (1984) 1.14
Endogenous and exogenous nitric oxide inhibits norepinephrine release from rat heart sympathetic nerves. Circ Res (1995) 1.13
Cytokine induction of NO synthase II in human DLD-1 cells: roles of the JAK-STAT, AP-1 and NF-kappaB-signaling pathways. Br J Pharmacol (1998) 1.13
Inhibitors of acyl-coenzyme A:lysolecithin acyltransferase activate the production of endothelium-derived vascular relaxing factor. J Pharmacol Exp Ther (1986) 1.10
Gossypol attenuates selectively the blood pressure lowering effect of endothelium-dependent vasodilators in the rabbit in vivo. Eur J Pharmacol (1988) 1.10
Selective inhibition by gossypol of endothelium-dependent relaxations augments relaxations to glyceryl trinitrate in rabbit coeliac artery. Br J Pharmacol (1987) 1.09
Nitric oxide synthases in neuronal cells, macrophages and endothelium are NADPH diaphorases, but represent only a fraction of total cellular NADPH diaphorase activity. Biochem Biophys Res Commun (1993) 1.09
Activation of protein kinase C alpha and/or epsilon enhances transcription of the human endothelial nitric oxide synthase gene. Mol Pharmacol (1998) 1.07
Endothelial cells have a particulate enzyme system responsible for EDRF formation: measurement by vascular relaxation. Biochem Biophys Res Commun (1991) 1.06
Endothelial cyclic GMP and cyclic AMP do not regulate the release of endothelium-derived relaxing factor/nitric oxide from bovine aortic endothelial cells. J Pharmacol Exp Ther (1991) 1.06
The endothelium-dependent relaxation of rabbit aorta: effects of antioxidants and hydroxylated eicosatetraenoic acids. Br J Pharmacol (1984) 1.05
Ca2+/calmodulin-regulated nitric oxide synthases. Cell Calcium (1992) 1.03
Endothelium-dependent vasodilation by melittin: are lipoxygenase products involved? Am J Physiol (1985) 1.02
Identification of the NO synthase isoforms expressed in human neutrophil granulocytes, megakaryocytes and platelets. Thromb Haemost (1997) 1.02
Dexamethasone suppresses eNOS and CAT-1 and induces oxidative stress in mouse resistance arterioles. Am J Physiol Heart Circ Physiol (2005) 1.01
PON3 is upregulated in cancer tissues and protects against mitochondrial superoxide-mediated cell death. Cell Death Differ (2012) 1.01
Production of an EDRF-like activity in the cytosol of N1E-115 neuroblastoma cells. FASEB J (1990) 1.01
Beyond reduction of atherosclerosis: PON2 provides apoptosis resistance and stabilizes tumor cells. Cell Death Dis (2011) 1.00
Differential distribution of nitric oxide synthase in neural pathways to the urogenital organs (urethra, penis, urinary bladder) of the rat. Brain Res (1994) 0.99
Nitric oxide synthase in the enteric nervous system of the guinea-pig: a quantitative description. Cell Tissue Res (1994) 0.99
In murine 3T3 fibroblasts, different second messenger pathways resulting in the induction of NO synthase II (iNOS) converge in the activation of transcription factor NF-kappaB. J Biol Chem (1996) 0.98
Endothelium-derived relaxing factor influences renal vascular resistance. Am J Physiol (1990) 0.97
The role of endothelial and non-endothelial prostaglandins in the relaxation of isolated blood vessels of the rabbit induced by acetylcholine and bradykinin. Br J Pharmacol (1986) 0.97
Endothelial nitric oxide synthase is myristylated. FEBS Lett (1992) 0.97
Involvement of NO in contact hypersensitivity. Int Immunol (1998) 0.95
Increased expression of constitutive nitric oxide synthase III, but not inducible nitric oxide synthase II, in human heart failure. J Am Coll Cardiol (1998) 0.95
Immunochemical detection of inducible NO synthase in human lung. Am J Physiol (1994) 0.94
Effects of intracerebroventricular administration of prostaglandin D2 on behaviour, blood pressure and body temperature as compared to prostaglandins E2 and F2 alpha. Psychopharmacology (Berl) (1983) 0.94
Endothelium-dependent relaxation of human epicardial coronary arteries: frequent lack of effect of acetylcholine. Eur J Pharmacol (1986) 0.94
Cerebral endothelial nitric oxide synthase expression after focal cerebral ischemia in rats. Stroke (1993) 0.94
Inducible NO synthase II and neuronal NO synthase I are constitutively expressed in different structures of guinea pig skeletal muscle: implications for contractile function. FASEB J (1996) 0.93
Nitric oxide synthase immunoreactivity in rat pontine medullary neurons. Neuroscience (1994) 0.92
Colocalization of nitric oxide synthase and NADPH-diaphorase in cultured myenteric neurones. Neuroreport (1992) 0.92
Characterization of endothelin-converting enzyme from endothelial cells and rat brain: detection of the formation of biologically active endothelin-1 by rapid bioassay. Mol Pharmacol (1992) 0.92
The transport activity of the human cationic amino acid transporter hCAT-1 is downregulated by activation of protein kinase C. Br J Pharmacol (2001) 0.91
Properties and mechanisms of production and action of endothelium-derived relaxing factor. J Cardiovasc Pharmacol (1986) 0.91
Nitric oxide synthase immunoreactivity in rat superior cervical ganglia and adrenal glands. Neurosci Lett (1993) 0.91
EDRF is an intracellular second messenger and autacoid to regulate cyclic GMP synthesis in many cells. Adv Second Messenger Phosphoprotein Res (1990) 0.90
Inhibition of small G proteins of the rho family by statins or clostridium difficile toxin B enhances cytokine-mediated induction of NO synthase II. Br J Pharmacol (2000) 0.90
Potential functional significance of brain-type and muscle-type nitric oxide synthase I expressed in adventitia and media of rat aorta. Arterioscler Thromb Vasc Biol (1999) 0.90
Induction of NADPH-dependent diaphorase and nitric oxide synthase activity in aortic smooth muscle and cultured macrophages. Mol Pharmacol (1992) 0.90
Nitric oxide synthase immunoreactivity and NADPH-diaphorase activity in a subpopulation of intrinsic neurones of the guinea-pig heart. Neurosci Lett (1992) 0.89
Maturation-related changes in endothelial nitric oxide synthase immunolocalization in developing ovine lung. Am J Physiol (1994) 0.88
Neuronal-type NO synthase: transcript diversity and expressional regulation. Nitric Oxide (1998) 0.88
Formation and elimination of prostacyclin metabolites in the cat in vivo as determined by radioimmunoassay of unextracted plasma. Eur J Pharmacol (1981) 0.87
Functional coupling of nitric oxide synthase and soluble guanylyl cyclase in controlling catecholamine secretion from bovine chromaffin cells. Neuroscience (1998) 0.87
Activation of soluble guanylyl cyclase by YC-1 in aortic smooth muscle but not in ventricular myocardium from rat. Br J Pharmacol (1997) 0.87
Expression of inducible nitric oxide synthase in failing and non-failing human heart. J Mol Cell Cardiol (1996) 0.87
Involvement of protein kinases in the induction of NO synthase II in human DLD-1 cells. Br J Pharmacol (1998) 0.86
Studies on the influence of thiamine on the synthesis of thiamine pyrophosphate-dependent enzymes in Saccharomyces cerevisiae. Biochim Biophys Acta (1970) 0.86
Upregulation of neuronal nitric oxide synthase and mRNA, and selective sparing of nitric oxide synthase-containing neurons after focal cerebral ischemia in rat. Brain Res (1994) 0.86
The inhibition of alpha 1-adrenoceptor-mediated contractions of rabbit pulmonary artery by Ca2+-withdrawal, pertussis toxin and N-ethylmaleimide is dependent on agonist intrinsic efficacy. Naunyn Schmiedebergs Arch Pharmacol (1989) 0.85
The importance of Ca2+-mediated phospholipase A2 activation for stimulus-evoked PGE2-release from rabbit splenic capsular strips. Naunyn Schmiedebergs Arch Pharmacol (1979) 0.84
Colocalization of nitric oxide synthase and somatostatin immunoreactivity in rat dentate hilar neurons. Proc Natl Acad Sci U S A (1994) 0.84
False labelling of dopaminergic terminals in the rabbit caudate nucleus: uptake and release of [3H]-5-hydroxytryptamine. Br J Pharmacol (1986) 0.84
Chemotactic peptide FMLP contracts human coronary arteries via cyclooxygenase products. Am J Physiol (1990) 0.83
Regional distribution of arachidonic acid metabolites in rat brain following convulsive stimuli. Prostaglandins (1981) 0.83
NG-methyl-L-arginine decreases contractility, cGMP and cAMP in isoproterenol-stimulated rat hearts in vitro. Eur J Pharmacol (1992) 0.82
The effect of proflavin in yeast cells. Biochim Biophys Acta (1968) 0.82
Endothelium-dependent vasodilatation in human epicardial coronary arteries: effect of prolonged exposure to glyceryl trinitrate or SIN-1. J Cardiovasc Pharmacol (1989) 0.82
Potential anticonvulsive properties of endogenous prostaglandins formed in mouse brain. Brain Res (1982) 0.81
Pharmacology of NO:cGMP signal transduction. Naunyn Schmiedebergs Arch Pharmacol (1998) 0.81
Ontogeny of nitric oxide synthase in the lumbosacral spinal cord of the neonatal rat. Brain Res Dev Brain Res (1994) 0.81
Failure of 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one (ODQ) to inhibit soluble guanylyl cyclase in rat ventricular cardiomyocytes. Br J Pharmacol (1999) 0.81
Ultraviolet A1 radiation induces nitric oxide synthase-2 expression in human skin endothelial cells in the absence of proinflammatory cytokines. J Invest Dermatol (2001) 0.80
Retinoic acid inhibits nitric oxide synthase-2 expression through the retinoic acid receptor-alpha. Biochem Biophys Res Commun (2000) 0.80
Heavy metal ion induction of adhesion molecules and cytokines in human endothelial cells: the role of NF-kappaB, I kappaB-alpha and AP-1. Pathobiology (1997) 0.80