Published in Proc Natl Acad Sci U S A on November 01, 1984
Supply and demand in cerebral energy metabolism: the role of nutrient transporters. J Cereb Blood Flow Metab (2007) 3.10
Crystal structure of the human glucose transporter GLUT1. Nature (2014) 2.12
Brain induces the expression of an early cell surface marker for blood-brain barrier-specific endothelium. EMBO J (1986) 1.22
Role of monosaccharide transport proteins in carbohydrate assimilation, distribution, metabolism, and homeostasis. Compr Physiol (2012) 1.01
Identification of the glucose transporter in mammalian cell membranes with a 125I-forskolin photoaffinity label. Biochem J (1988) 0.96
Neurothelin: an inducible cell surface glycoprotein of blood-brain barrier-specific endothelial cells and distinct neurons. J Cell Biol (1990) 0.95
Barrier properties of testis microvessels. Proc Natl Acad Sci U S A (1993) 0.95
Neurons and microvessels express the brain glucose transporter protein GLUT3. Proc Natl Acad Sci U S A (1992) 0.93
Glucose transporters are abundant in cells with "occluding" junctions at the blood-eye barriers. Proc Natl Acad Sci U S A (1990) 0.87
Identification and characterization of the glucose-transport protein of the bovine blood/brain barrier. Biochem J (1987) 0.86
AMP kinase regulation of sugar transport in brain capillary endothelial cells during acute metabolic stress. Am J Physiol Cell Physiol (2012) 0.85
Possible multifunction of glucose transporter. Transport of nicotinamide by reconstituted liposomes. Biochem J (1992) 0.85
Glucose transporters in isolated chromaffin cells. Effects of insulin and secretagogues. Biochem J (1987) 0.83
Purification and characterization of metabolically active capillaries of the blood-brain barrier. Biochem J (1991) 0.83
Angiotensin II receptor binding sites in brain microvessels. Proc Natl Acad Sci U S A (1985) 0.83
GLUT-1 glucose transporters in the blood-brain barrier: differential phosphorylation. J Neurosci Res (2011) 0.83
Glucose transporter 1 and monocarboxylate transporters 1, 2, and 4 localization within the glial cells of shark blood-brain-barriers. PLoS One (2012) 0.83
Chronic stress modulates regional cerebral glucose transporter expression in an age-specific and sexually-dimorphic manner. Physiol Behav (2013) 0.81
Correlation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity with blood-brain barrier monoamine oxidase activity. Proc Natl Acad Sci U S A (1987) 0.80
Shuttling glucose across brain microvessels, with a little help from GLUT1 and AMP kinase. Focus on "AMP kinase regulation of sugar transport in brain capillary endothelial cells during acute metabolic stress". Am J Physiol Cell Physiol (2012) 0.78
Creatine salts provide neuroprotection even after partial impairment of the creatine transporter. Neuroscience (2016) 0.75
Ultrasound effects on brain-targeting mannosylated liposomes: in vitro and blood-brain barrier transport investigations. Drug Des Devel Ther (2015) 0.75
Blood-brain barrier transport machineries and targeted therapy of brain diseases. Bioimpacts (2016) 0.75
Molecular determinants for the thermodynamic and functional divergence of uniporter GLUT1 and proton symporter XylE. PLoS Comput Biol (2017) 0.75
Protein measurement with the Folin phenol reagent. J Biol Chem (1951) 1743.91
Fine structural localization of a blood-brain barrier to exogenous peroxidase. J Cell Biol (1967) 9.74
Insulin-stimulated translocation of glucose transport systems in the isolated rat adipose cell. Time course, reversal, insulin concentration dependency, and relationship to glucose transport activity. J Biol Chem (1981) 3.28
Brain metabolism: a perspective from the blood-brain barrier. Physiol Rev (1983) 2.46
Facilitated transfer of glucose from blood into brain tissue. J Physiol (1965) 2.12
Mechanism of insulin action on glucose transport in the isolated rat adipose cell. Enhancement of the number of functional transport systems. J Biol Chem (1978) 1.99
ISOLATION OF GAMMA-GLUTAMYL TRANSPEPTIDASE FROM HOG KIDNEY. J Biol Chem (1965) 1.68
Morphology of blood-brain interfaces. Exp Eye Res (1977) 1.65
Transport of glucose from blood to brain. Physiol Rev (1979) 1.62
Detection of the rat adipose cell glucose transporter with antibody against the human red cell glucose transporter. Biochem Biophys Res Commun (1982) 1.46
Cytochalasin B. A natural photoaffinity ligand for labeling the human erythrocyte glucose transporter. J Biol Chem (1982) 1.44
Adrenergic and cholinergic receptors of cerebral microvessels. J Cereb Blood Flow Metab (1981) 1.43
Monosaccharide transport proteins of the human erythrocyte membrane. Biochim Biophys Acta (1981) 1.36
Kinetics of blood-brain transport of hexoses. Biochim Biophys Acta (1975) 1.32
Isolation and characterization of brain endothelial cells: morphology and enzyme activity. J Neurochem (1980) 1.21
Proteins antigenically related to the human erythrocyte glucose transporter in normal and Rous sarcoma virus-transformed chicken embryo fibroblasts. Proc Natl Acad Sci U S A (1982) 1.20
Equilibria and kinetics of ligand binding to the human erythrocyte glucose transporter. Evidence for an alternating conformation model for transport. Biochemistry (1981) 1.17
Immunological identification of an insulin-responsive glucose transporter. Biochem Biophys Res Commun (1982) 1.09
Kinetics of unidirectional glucose transport into the isolated dog brain. Am J Physiol (1973) 1.07
Identification of the D-glucose-inhibitable cytochalasin B binding site as the glucose transporter in rat diaphragm plasma and microsomal membranes. Biochim Biophys Acta (1983) 1.03
The glucose transport system of muscle plasma membranes: characterization by means of [3H]cytochalasin B binding. Arch Biochem Biophys (1983) 1.01
Identification of the glucose transporter in rat skeletal muscle. Arch Biochem Biophys (1983) 1.00
Identification of the stereospecific hexose transporter from starved and fed chicken embryo fibroblasts. Proc Natl Acad Sci U S A (1982) 0.99
Insulin and the way the brain handles glucose. J Neurochem (1975) 0.99
Studies on gamma-glutamyl transpeptidase activity and its histochemical localization in the central nervous system of man and different animal species. Acta Histochem (1966) 0.99
Modulation of substrate transport to the brain. Acta Neurol Scand (1983) 0.97
Photolabeling of glucose-sensitive cytochalasin B binding proteins in erythrocyte, fibroblast and adipocyte membranes. Biochem Biophys Res Commun (1982) 0.94
Labelling of the human erythrocyte glucose transporter with 3H-labelled cytochalasin B occurs via protein photoactivation. Biochim Biophys Acta (1984) 0.90
Hexose transport and phosphorylation by capillaries isolated from rat brain. Am J Physiol (1979) 0.90
Characterization of the blood-brain barrier: protein composition of the capillary endothelial cell membrane. J Neurochem (1983) 0.89
Sodium transport in capillaries isolated from rat brain. J Neurochem (1983) 0.87
Rapid steady-state analysis of blood-brain glucose transfer in rat. Acta Physiol Scand (1980) 0.82
Identification of the glucose transport protein of the microvillous membrane of human placenta by photoaffinity labelling. Biochem Biophys Res Commun (1982) 0.81
Cytochalasin B inhibition of brain glucose transport and the influence of blood components on inhibitor concentration. Biochim Biophys Acta (1977) 0.81
Transport of sugars into microvessels isolated from rat brain: a model for the blood-brain barrier. J Neurochem (1979) 0.78
Cellular mechanism of metformin action involves glucose transporter translocation from an intracellular pool to the plasma membrane in L6 muscle cells. Endocrinology (1992) 2.94
Protein kinase B/Akt participates in GLUT4 translocation by insulin in L6 myoblasts. Mol Cell Biol (1999) 2.91
The prevalence and intra-oral distribution of Candida albicans in man. Arch Oral Biol (1980) 2.54
Oral candidal populations in health and disease. Br Dent J (1979) 2.48
Defective glucose transport across the blood-brain barrier as a cause of persistent hypoglycorrhachia, seizures, and developmental delay. N Engl J Med (1991) 2.48
Exercise induces recruitment of the "insulin-responsive glucose transporter". Evidence for distinct intracellular insulin- and exercise-recruitable transporter pools in skeletal muscle. J Biol Chem (1990) 2.27
Oral submucous fibrosis. A review. Aust Dent J (1996) 2.06
Defect of cell-mediated immunity in patients with iron-deficiency anaemia. Lancet (1972) 2.01
Insulin action on glucose transport and plasma membrane GLUT4 content in skeletal muscle from patients with NIDDM. Diabetologia (1996) 1.76
Stimulation of glucose transport in skeletal muscle by hypoxia. J Appl Physiol (1985) (1991) 1.67
Disassembly of the actin network inhibits insulin-dependent stimulation of glucose transport and prevents recruitment of glucose transporters to the plasma membrane. J Biol Chem (1994) 1.67
Development regulation of the subcellular distribution and glycosylation of GLUT1 and GLUT4 glucose transporters during myogenesis of L6 muscle cells. J Biol Chem (1992) 1.62
Visual hallucinations associated with fluoxetine and sertraline. J Clin Psychopharmacol (1998) 1.58
Actin filaments participate in the relocalization of phosphatidylinositol3-kinase to glucose transporter-containing compartments and in the stimulation of glucose uptake in 3T3-L1 adipocytes. Biochem J (1998) 1.57
Insulin-induced actin filament remodeling colocalizes actin with phosphatidylinositol 3-kinase and GLUT4 in L6 myotubes. J Cell Sci (2000) 1.56
Insulin-stimulated translocation of GLUT4 glucose transporters requires SNARE-complex proteins. Proc Natl Acad Sci U S A (1996) 1.52
An arteriographic study of mesenteric arterial disease. I. Large vessel changes. Gut (1967) 1.52
Candidal infections and populations of Candida albicans in mouths of diabetics. J Clin Pathol (1981) 1.51
Multiple roles of phosphatidylinositol 3-kinase in regulation of glucose transport, amino acid transport, and glucose transporters in L6 skeletal muscle cells. Endocrinology (1995) 1.50
Identification of a human homologue of the vesicle-associated membrane protein (VAMP)-associated protein of 33 kDa (VAP-33): a broadly expressed protein that binds to VAMP. Biochem J (1998) 1.46
Syntaxin 4 in 3T3-L1 adipocytes: regulation by insulin and participation in insulin-dependent glucose transport. Mol Biol Cell (1996) 1.45
VAMP2, but not VAMP3/cellubrevin, mediates insulin-dependent incorporation of GLUT4 into the plasma membrane of L6 myoblasts. Mol Biol Cell (2000) 1.45
GLUT4 translocation by insulin in intact muscle cells: detection by a fast and quantitative assay. FEBS Lett (1998) 1.45
The cytoplasmic domain of L-selectin interacts with cytoskeletal proteins via alpha-actinin: receptor positioning in microvilli does not require interaction with alpha-actinin. J Cell Biol (1995) 1.44
Insulin-induced cortical actin remodeling promotes GLUT4 insertion at muscle cell membrane ruffles. J Clin Invest (2001) 1.44
Adrenergic and cholinergic receptors of cerebral microvessels. J Cereb Blood Flow Metab (1981) 1.43
Hormonal regulation of the Na(+)-K(+)-ATPase: mechanisms underlying rapid and sustained changes in pump activity. Am J Physiol (1995) 1.42
An inhibitor of p38 mitogen-activated protein kinase prevents insulin-stimulated glucose transport but not glucose transporter translocation in 3T3-L1 adipocytes and L6 myotubes. J Biol Chem (1999) 1.41
The relationship of amyloid plaques to cerebral capillaries in Alzheimer's disease. Am J Pathol (1990) 1.40
Membrane-permeant esters of phosphatidylinositol 3,4,5-trisphosphate. J Biol Chem (1998) 1.38
The insulin signaling pathway. J Membr Biol (1999) 1.38
Insulin induces the translocation of GLUT4 from a unique intracellular organelle to transverse tubules in rat skeletal muscle. Diabetes (1992) 1.38
Insulin induces translocation of the alpha 2 and beta 1 subunits of the Na+/K(+)-ATPase from intracellular compartments to the plasma membrane in mammalian skeletal muscle. J Biol Chem (1992) 1.37
The inability of phosphatidylinositol 3-kinase activation to stimulate GLUT4 translocation indicates additional signaling pathways are required for insulin-stimulated glucose uptake. Proc Natl Acad Sci U S A (1995) 1.37
Abundance, localization, and insulin-induced translocation of glucose transporters in red and white muscle. Am J Physiol (1992) 1.36
GLUT-4myc ectopic expression in L6 myoblasts generates a GLUT-4-specific pool conferring insulin sensitivity. Am J Physiol (1999) 1.34
Glucose transport in human skeletal muscle cells in culture. Stimulation by insulin and metformin. J Clin Invest (1992) 1.33
Persistence of mucosal abnormality in ulcerative colitis. Gut (1966) 1.32
Requirement for Akt (protein kinase B) in insulin-induced activation of glycogen synthase and phosphorylation of 4E-BP1 (PHAS-1). J Biol Chem (1999) 1.31
Stimulation of glucose uptake by the natural coenzyme alpha-lipoic acid/thioctic acid: participation of elements of the insulin signaling pathway. Diabetes (1996) 1.30
Denture stomatitis: a review. J Oral Rehabil (1987) 1.30
Cimetidine in the prevention of gastric ulcer relapse. Postgrad Med J (1979) 1.29
Cellubrevin is a resident protein of insulin-sensitive GLUT4 glucose transporter vesicles in 3T3-L1 adipocytes. J Biol Chem (1995) 1.28
Small G proteins in insulin action: Rab and Rho families at the crossroads of signal transduction and GLUT4 vesicle traffic. Acta Physiol (Oxf) (2008) 1.27
Neurologic presentation of decompression sickness and air embolism in sport divers. Neurology (1985) 1.26
Exercise-induced increase in glucose transporters in plasma membranes of rat skeletal muscle. Endocrinology (1989) 1.25
Regulation of glucose transport and GLUT1 glucose transporter expression by O2 in muscle cells in culture. Am J Physiol (1992) 1.25
Spontaneously remitting spinal epidural hematoma in a patient on anticoagulants. N Engl J Med (1971) 1.25
Establishing a normal range for mouth opening: its use in screening for oral submucous fibrosis. Br J Oral Maxillofac Surg (1997) 1.24
Differential effects of phosphatidylinositol 3-kinase inhibition on intracellular signals regulating GLUT4 translocation and glucose transport. J Biol Chem (2001) 1.22
Interactions with the pharmaceutical industry: a survey of family medicine residents in Ontario. CMAJ (1996) 1.22
GLUT4 translocation precedes the stimulation of glucose uptake by insulin in muscle cells: potential activation of GLUT4 via p38 mitogen-activated protein kinase. Biochem J (2001) 1.21
SNAP23 promotes insulin-dependent glucose uptake in 3T3-L1 adipocytes: possible interaction with cytoskeleton. Am J Physiol (1999) 1.21
Binary interactions of the SNARE proteins syntaxin-4, SNAP23, and VAMP-2 and their regulation by phosphorylation. Biochemistry (1998) 1.21
Insulin activates a p21-activated kinase in muscle cells via phosphatidylinositol 3-kinase. J Biol Chem (1996) 1.21
Differential expression of the GLUT1 and GLUT4 glucose transporters during differentiation of L6 muscle cells. Biochem Biophys Res Commun (1991) 1.21
Activation of p38 mitogen-activated protein kinase alpha and beta by insulin and contraction in rat skeletal muscle: potential role in the stimulation of glucose transport. Diabetes (2000) 1.20
VAP-A binds promiscuously to both v- and tSNAREs. Biochem Biophys Res Commun (2001) 1.19
Tobacco smoking and denture wearing in oral candidal leukoplakia. Br Dent J (1983) 1.18
Differential regulation of the GLUT-1 and GLUT-4 glucose transport systems by glucose and insulin in L6 muscle cells in culture. J Biol Chem (1991) 1.18
Indinavir uncovers different contributions of GLUT4 and GLUT1 towards glucose uptake in muscle and fat cells and tissues. Diabetologia (2003) 1.18
SNAP-23 is not cleaved by botulinum neurotoxin E and can replace SNAP-25 in the process of insulin secretion. J Biol Chem (1997) 1.17
Induction of sugar uptake response to insulin by serum depletion in fusing L6 myoblasts. Am J Physiol (1984) 1.17
Expression of vesicle-associated membrane protein 2 (VAMP-2)/synaptobrevin II and cellubrevin in rat skeletal muscle and in a muscle cell line. Biochem J (1994) 1.16
Characterization and subcellular localization of target membrane soluble NSF attachment protein receptors (t-SNAREs) in macrophages. Syntaxins 2, 3, and 4 are present on phagosomal membranes. J Immunol (1996) 1.15
Anterolateral rotatory instability of the knee joint. An early analysis of the Ellison procedure. J Bone Joint Surg Am (1978) 1.14
Mechanism and regulation of GLUT-4 vesicle fusion in muscle and fat cells. Am J Physiol Cell Physiol (2000) 1.14
Rapid stimulation of glucose transport by mitochondrial uncoupling depends in part on cytosolic Ca2+ and cPKC. Am J Physiol (1998) 1.14
Reduced glucose transporter at the blood-brain barrier and in cerebral cortex in Alzheimer disease. J Neurochem (1989) 1.14
Subcellular distribution of docking/fusion proteins in neutrophils, secretory cells with multiple exocytic compartments. J Immunol (1995) 1.14
Calcifying epithelial odontogenic (Pindborg) tumor with malignant transformation and metastatic spread. Head Neck (2001) 1.13
A case of aggressive multiple metachronous central giant cell granulomas of the jaws: differential diagnosis and management options. Int J Oral Maxillofac Surg (2005) 1.13
Actin filaments facilitate insulin activation of the src and collagen homologous/mitogen-activated protein kinase pathway leading to DNA synthesis and c-fos expression. J Biol Chem (1998) 1.13
The glucose transporter of the human brain and blood-brain barrier. Ann Neurol (1988) 1.12
Glucose transport activity in L6 muscle cells is regulated by the coordinate control of subcellular glucose transporter distribution, biosynthesis, and mRNA transcription. J Biol Chem (1990) 1.12
Troglitazone causes acute mitochondrial membrane depolarisation and an AMPK-mediated increase in glucose phosphorylation in muscle cells. Diabetologia (2005) 1.11
Hyperosmolarity reduces GLUT4 endocytosis and increases its exocytosis from a VAMP2-independent pool in l6 muscle cells. J Biol Chem (2001) 1.11
Exocrine and endocrine pancreatic function in diabetes mellitus and chronic pancreatitis. Gut (1966) 1.11
Improving survival in the 6 months after diagnosis of heart failure in the past decade: population-based data from the UK. Heart (2009) 1.09
Photoactive covalent labeling of membrane components from within the lipid core. Biochem Biophys Res Commun (1974) 1.08
Sicca syndrome associated with idiopathic haemochromatosis. Br Med J (1979) 1.07
Insulin accelerates inter-endosomal GLUT4 traffic via phosphatidylinositol 3-kinase and protein kinase B. J Biol Chem (2001) 1.07
Mechanisms of adaptation of glucose transporters to changes in the oxidative chain of muscle and fat cells. Am J Physiol (1993) 1.07
Technique for suction biopsy of the rectal mucosa. Gut (1970) 1.07
Factors contributing to chromosome damage in lymphocytes of cigarette smokers. Mutat Res (1991) 1.06
Engagement of the insulin-sensitive pathway in the stimulation of glucose transport by alpha-lipoic acid in 3T3-L1 adipocytes. Diabetologia (2000) 1.06
Glucose uptake in human and animal muscle cells in culture. Biochem Cell Biol (1990) 1.05
Postganglionic cholinergic dysautonomia. Ann Neurol (1977) 1.05
Glycaemia regulates the glucose transporter number in the plasma membrane of rat skeletal muscle. Biochem J (1992) 1.05
Orofacial granulomatosis in childhood. Br Dent J (1987) 1.04
Plasma insulin in pancreatic disease. Gut (1970) 1.04
Inhibition of Escherichia coli glutamine synthetase by alpha- and gamma-substituted phosphinothricins. Biochemistry (1990) 1.03
Substrate variability as a factor in enzyme inhibitor design: inhibition of ovine brain glutamine synthetase by alpha- and gamma-substituted phosphinothricins. Biochemistry (1989) 1.03
Role of the actin cytoskeleton in insulin action. Microsc Res Tech (1999) 1.03
The insulin-dependent biosynthesis of GLUT1 and GLUT3 glucose transporters in L6 muscle cells is mediated by distinct pathways. Roles of p21ras and pp70 S6 kinase. J Biol Chem (1995) 1.03
A functional role for VAP-33 in insulin-stimulated GLUT4 traffic. Traffic (2000) 1.03
Alpha-hydrazino-ornithine blocks net synthesis of putrescine but not of RNA and DNA. Nature (1974) 1.02
Perturbation of dynamin II with an amphiphysin SH3 domain increases GLUT4 glucose transporters at the plasma membrane in 3T3-L1 adipocytes. Dynamin II participates in GLUT4 endocytosis. J Biol Chem (1998) 1.01