Published in Science on March 27, 1981
Dynamic instability of individual microtubules analyzed by video light microscopy: rate constants and transition frequencies. J Cell Biol (1988) 9.32
Large surface proteins of hepatitis B virus containing the pre-s sequence. J Virol (1984) 6.90
Rapid diagnosis of rotavirus infection by direct detection of viral nucleic acid in silver-stained polyacrylamide gels. J Clin Microbiol (1982) 5.80
Protein translocation across the endoplasmic reticulum. II. Isolation and characterization of the signal recognition particle receptor. J Cell Biol (1982) 5.20
Purification and characterization of a newly identified growth factor specific for epithelial cells. Proc Natl Acad Sci U S A (1989) 5.10
Dynactin, a conserved, ubiquitously expressed component of an activator of vesicle motility mediated by cytoplasmic dynein. J Cell Biol (1991) 5.02
Isolation of brain fibroblast growth factor by heparin-Sepharose affinity chromatography: identity with pituitary fibroblast growth factor. Proc Natl Acad Sci U S A (1984) 4.41
A 38,000-dalton membrane protein (p38) present in synaptic vesicles. Proc Natl Acad Sci U S A (1985) 4.35
Specific factor conferring nuclease hypersensitivity at the 5' end of the chicken adult beta-globin gene. Proc Natl Acad Sci U S A (1984) 4.03
Cloning and sequencing of the metallothioprotein beta-lactamase II gene of Bacillus cereus 569/H in Escherichia coli. J Bacteriol (1985) 3.95
Ultrastructural analysis of the dynactin complex: an actin-related protein is a component of a filament that resembles F-actin. J Cell Biol (1994) 3.74
Immunological evaluation of a component isolated from Mycobacterium bovis BCG with a monoclonal antibody to M. bovis BCG. Infect Immun (1984) 3.46
Involvement of Plasma Membrane Alterations in Cold Acclimation of Winter Rye Seedlings (Secale cereale L. cv Puma). Plant Physiol (1984) 3.29
Host-Pathogen Interactions : XXV. Endopolygalacturonic Acid Lyase from Erwinia carotovora Elicits Phytoalexin Accumulation by Releasing Plant Cell Wall Fragments. Plant Physiol (1984) 3.25
Reinforced Polyproline II Conformation in a Hydroxyproline-Rich Cell Wall Glycoprotein from Carrot Root. Plant Physiol (1984) 3.15
Assembly polypeptides from coated vesicles mediate reassembly of unique clathrin coats. J Cell Biol (1983) 3.06
Mutations at twelve independent loci result in absence of outer dynein arms in Chylamydomonas reinhardtii. J Cell Biol (1988) 3.04
Affinity purification and characterization of Shiga-like toxin II and production of toxin-specific monoclonal antibodies. Infect Immun (1988) 2.99
A-CAM: a 135-kD receptor of intercellular adherens junctions. I. Immunoelectron microscopic localization and biochemical studies. J Cell Biol (1986) 2.98
Alzheimer paired helical filaments: bulk isolation, solubility, and protein composition. Acta Neuropathol (1984) 2.97
Cellular receptor for 125I-labeled tumor necrosis factor: specific binding, affinity labeling, and relationship to sensitivity. Proc Natl Acad Sci U S A (1985) 2.92
Characterization of nonattaching mutants of Agrobacterium tumefaciens. J Bacteriol (1987) 2.92
Characterization of a murine lymphokine distinct from interleukin 2 and interleukin 3 (IL-3) possessing a T-cell growth factor activity and a mast-cell growth factor activity that synergizes with IL-3. Proc Natl Acad Sci U S A (1986) 2.84
U5 small nuclear ribonucleoprotein: RNA structure analysis and ATP-dependent interaction with U4/U6. Mol Cell Biol (1989) 2.82
Kinetic analysis of channel gating. Application to the cholinergic receptor channel and the chloride channel from Torpedo californica. Biophys J (1985) 2.77
Molecular cloning of pectate lyase genes from Erwinia chrysanthemi and their expression in Escherichia coli. J Bacteriol (1984) 2.77
Protein and Lipid Compositions of Isolated Plasma Membranes from Orchard Grass (Dactylis glomerata L.) and Changes during Cold Acclimation. Plant Physiol (1984) 2.69
Multiple modes of activation of latent human fibroblast collagenase: evidence for the role of a Cys73 active-site zinc complex in latency and a "cysteine switch" mechanism for activation. Proc Natl Acad Sci U S A (1990) 2.68
Isolation and Partial Characterization of the Major Amide-Linked Conjugate of Indole-3-Acetic Acid from Phaseolus vulgaris L. Plant Physiol (1986) 2.58
Two types of Chlamydomonas flagellar mutants missing different components of inner-arm dynein. J Cell Biol (1991) 2.52
In vitro neutralization of Chlamydia trachomatis with monoclonal antibody to an epitope on the major outer membrane protein. Infect Immun (1984) 2.48
Characterization of monoclonal antibodies against Chlamydomonas flagellar dyneins by high-resolution protein blotting. Proc Natl Acad Sci U S A (1985) 2.47
Isolation of a relatively nontoxic 65-kilodalton protein inclusion from the parasporal body of Bacillus thuringiensis subsp. israelensis. J Bacteriol (1986) 2.45
Identification of the cap binding protein of influenza virus. Nucleic Acids Res (1982) 2.44
The membrane glycoprotein Ia-IIa (VLA-2) complex mediates the Mg++-dependent adhesion of platelets to collagen. J Cell Biol (1989) 2.44
Ligninolytic enzymes of the white-rot fungus Phlebia radiata. Biochem J (1988) 2.42
Purified cytochrome b from human granulocyte plasma membrane is comprised of two polypeptides with relative molecular weights of 91,000 and 22,000. J Clin Invest (1987) 2.40
Immunoglobulin G antibodies directed against protein III block killing of serum-resistant Neisseria gonorrhoeae by immune serum. J Exp Med (1986) 2.40
Construction and characterization of chromosomal insertional mutations of the Pseudomonas aeruginosa exoenzyme S trans-regulatory locus. Infect Immun (1994) 2.36
Lupus autoantibodies target ribosomal P proteins. J Exp Med (1985) 2.28
The role of kinesin and other soluble factors in organelle movement along microtubules. J Cell Biol (1988) 2.27
The minor myosin heavy chain, mhcA, of Caenorhabditis elegans is necessary for the initiation of thick filament assembly. EMBO J (1989) 2.26
RNA-binding proteins of bovine rotavirus. J Virol (1986) 2.26
Purification and characterization of the Lactobacillus acidophilus bacteriocin lactacin B. Antimicrob Agents Chemother (1984) 2.22
Isolation of an RNA-directed RNA polymerase-specific cDNA clone from tomato. Plant Cell (1998) 2.17
Map position and nucleotide sequence of the gene for the large structural phosphoprotein of human cytomegalovirus. J Virol (1987) 2.11
Poliovirus RNA-dependent RNA polymerase and host cell protein synthesize product RNA twice the size of poliovirion RNA in vitro. J Virol (1985) 2.11
Characterization of antigens from nontypable Haemophilus influenzae recognized by human bactericidal antibodies. Role of Haemophilus outer membrane proteins. J Clin Invest (1985) 2.09
A 5S rRNA/L5 complex is a precursor to ribosome assembly in mammalian cells. J Cell Biol (1988) 2.08
Response of mice to rotaviruses of bovine or primate origin assessed by radioimmunoassay, radioimmunoprecipitation, and plaque reduction neutralization. Infect Immun (1983) 2.06
Purification and characterization of macrolide 2'-phosphotransferase from a strain of Escherichia coli that is highly resistant to erythromycin. Antimicrob Agents Chemother (1989) 2.05
Hepadnavirus infection requires interaction between the viral pre-S domain and a specific hepatocellular receptor. J Virol (1993) 2.05
Hevea Linamarase-A Nonspecific beta-Glycosidase. Plant Physiol (1987) 2.00
Expression of a microinjected immunoglobulin gene in the spleen of transgenic mice. Nature (1984) 2.00
Resistance of nicotiana benthamiana to phytophthora infestans is mediated by the recognition of the elicitor protein INF1 Plant Cell (1998) 1.97
Proteins that rescue A-signal-defective mutants of Myxococcus xanthus. J Bacteriol (1992) 1.96
Electrophoretic transfer as a technique for the detection and identification of plant amylolytic enzymes in polyacrylamide gels. Plant Physiol (1984) 1.94
An endogenous alpha-amylase inhibitor in barley kernels. Plant Physiol (1983) 1.93
An unconventional myosin heavy chain gene from Drosophila melanogaster. J Cell Biol (1992) 1.92
Vaccination with the major secretory protein of Legionella pneumophila induces cell-mediated and protective immunity in a guinea pig model of Legionnaires' disease. J Exp Med (1989) 1.91
Amphiregulin: a bifunctional growth-modulating glycoprotein produced by the phorbol 12-myristate 13-acetate-treated human breast adenocarcinoma cell line MCF-7. Proc Natl Acad Sci U S A (1988) 1.91
Molecular properties of the Ro/SSA antigen and enzyme-linked immunosorbent assay for quantitation of antibody. J Clin Invest (1984) 1.90
EAP, a highly conserved cellular protein associated with Epstein-Barr virus small RNAs (EBERs). EMBO J (1991) 1.90
Characterization of gelatinase from pig polymorphonuclear leucocytes. A metalloproteinase resembling tumour type IV collagenase. Biochem J (1989) 1.89
Regulation of actin mRNA levels and translation responds to changes in cell configuration. Mol Cell Biol (1983) 1.86
Autoactivation of catalytic (C alpha) subunit of cyclic AMP-dependent protein kinase by phosphorylation of threonine 197. Mol Cell Biol (1993) 1.84
An RNA polymerase II transcription factor has an associated DNA-dependent ATPase (dATPase) activity strongly stimulated by the TATA region of promoters. Proc Natl Acad Sci U S A (1989) 1.81
Role of mRNA competition in regulating translation: further characterization of mRNA discriminatory initiation factors. Proc Natl Acad Sci U S A (1983) 1.81
A T-lymphoma transmembrane glycoprotein (gp180) is linked to the cytoskeletal protein, fodrin. J Cell Biol (1985) 1.80
Chemotactic behavior of Campylobacter jejuni. Infect Immun (1988) 1.80
Detection of erythrocyte membrane proteins, sialoglycoproteins, and lipids in the same polyacrylamide gel using a double-staining technique. Proc Natl Acad Sci U S A (1984) 1.76
Purification and characterization of mammalian integrins expressed by a rat neuronal cell line (PC12): evidence that they function as alpha/beta heterodimeric receptors for laminin and type IV collagen. J Cell Biol (1988) 1.76
Drosophilia spectrin. I. Characterization of the purified protein. J Cell Biol (1987) 1.72
Purification and characterization of maleylacetate reductase from Alcaligenes eutrophus JMP134(pJP4). J Bacteriol (1993) 1.72
High levels of p19/nm23 protein in neuroblastoma are associated with advanced stage disease and with N-myc gene amplification. J Clin Invest (1991) 1.70
Isolation and characterization of two chondroitin lyases from Bacteroides thetaiotaomicron. J Bacteriol (1983) 1.70
Isolation of a receptor protein involved in attachment of human rhinoviruses. J Virol (1986) 1.68
A Phytophthora infestans cystatin-like protein targets a novel tomato papain-like apoplastic protease. Plant Physiol (2006) 1.67
Purification and characterization of a 1,2-dihydroxynaphthalene dioxygenase from a bacterium that degrades naphthalenesulfonic acids. J Bacteriol (1991) 1.67
Molecular cloning and characterization of the ryanodine receptor/junctional channel complex cDNA from skeletal muscle sarcoplasmic reticulum. Proc Natl Acad Sci U S A (1989) 1.67
Adherence, coaggregation, and hydrophobicity of Streptococcus gordonii associated with expression of cell surface lipoproteins. Infect Immun (1992) 1.64
Purification and characterization of an exo-beta-1,4-glucanase from Ruminococcus flavefaciens FD-1. J Bacteriol (1987) 1.62
Plantaricins S and T, Two New Bacteriocins Produced by Lactobacillus plantarum LPCO10 Isolated from a Green Olive Fermentation. Appl Environ Microbiol (1993) 1.61
Characterization of a new antigenic type, Kuroki, of Rickettsia tsutsugamushi isolated from a patient in Japan. J Clin Microbiol (1990) 1.60
T cell suppressor factor from human glioblastoma cells is a 12.5-kd protein closely related to transforming growth factor-beta. EMBO J (1987) 1.59
Alginase enzyme production by Bacillus circulans. Appl Environ Microbiol (1984) 1.59
Localization of kinesin in cultured cells. J Cell Biol (1988) 1.58
Direct phenotypic and genotypic detection of a recombinant pseudomonad population released into lake water. Appl Environ Microbiol (1989) 1.58
Evidence for nuclear factors involved in recognition of 5' splice sites. Nucleic Acids Res (1989) 1.58
Purification and characterization of dichloromuconate cycloisomerase from Alcaligenes eutrophus JMP 134. Biochem J (1990) 1.58
Silver staining of proteins in polyacrylamide gels. Nat Protoc (2006) 1.58
Characterization of DNA sequence-common and sequence-specific proteins binding to cis-acting sites for cleavage of the terminal a sequence of the herpes simplex virus 1 genome. J Virol (1989) 1.57
Identification of the major capsid protein gene of human cytomegalovirus. J Virol (1989) 1.56
Purification and properties of Myxococcus xanthus C-factor, an intercellular signaling protein. Proc Natl Acad Sci U S A (1990) 1.55
Substructure of human von Willebrand factor. J Clin Invest (1985) 1.55
Cloning, nucleotide sequence, and expression of the Bacillus subtilis ans operon, which codes for L-asparaginase and L-aspartase. J Bacteriol (1991) 1.54
Aspartate aminotransferase in alfalfa root nodules : I. Purification and partial characterization. Plant Physiol (1989) 1.52
Use of a mammalian internal ribosomal entry site element for expression of a foreign protein by a transfectant influenza virus. J Virol (1994) 1.50
Complementary DNA sequencing: expressed sequence tags and human genome project. Science (1991) 19.42
Effect of COMT Val108/158 Met genotype on frontal lobe function and risk for schizophrenia. Proc Natl Acad Sci U S A (2001) 9.42
Dating the origin of the CCR5-Delta32 AIDS-resistance allele by the coalescence of haplotypes. Am J Hum Genet (1998) 5.24
A highly sensitive silver stain for detecting proteins and peptides in polyacrylamide gels. Anal Biochem (1979) 4.77
Trace polypeptides in cellular extracts and human body fluids detected by two-dimensional electrophoresis and a highly sensitive silver stain. Proc Natl Acad Sci U S A (1979) 4.11
Reduced plasma dehydroepiandrosterone concentrations in Alzheimer's disease. Lancet (1989) 3.69
A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Proc Natl Acad Sci U S A (1983) 3.39
Evidence for genetic linkage to alcohol dependence on chromosomes 4 and 11 from an autosome-wide scan in an American Indian population. Am J Med Genet (1998) 3.37
Gel protein stains: silver stain. Methods Enzymol (1984) 3.18
Access of vulnerable groups to antiretroviral therapy among persons in care for HIV disease in the United States. HCSUS Consortium. HIV Cost and Services Utilization Study. Health Serv Res (2000) 3.09
Ancestral Asian source(s) of new world Y-chromosome founder haplotypes. Am J Hum Genet (1999) 2.89
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Ocular retardation mouse caused by Chx10 homeobox null allele: impaired retinal progenitor proliferation and bipolar cell differentiation. Nat Genet (1996) 2.75
Chronic Parkinsonism secondary to intravenous injection of meperidine analogues. Psychiatry Res (1979) 2.61
The new drugs (chlorpromazine & reserpine): administrative aspects. 1956. Psychiatr Serv (2000) 2.58
A global survey of haplotype frequencies and linkage disequilibrium at the DRD2 locus. Hum Genet (1998) 2.44
A rapid sensitive silver stain for polypeptides in polyacrylamide gels. Anal Biochem (1981) 2.42
Polymorphic admixture typing in human ethnic populations. Am J Hum Genet (1994) 2.37
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A relationship between serotonin transporter genotype and in vivo protein expression and alcohol neurotoxicity. Biol Psychiatry (2000) 2.32
Affinity generation of single-stranded DNA for dideoxy sequencing following the polymerase chain reaction. Anal Biochem (1989) 2.29
Brain-derived neurotrophic factor val66met polymorphism and volume of the hippocampal formation. Mol Psychiatry (2005) 2.29
Genotype influences in vivo dopamine transporter availability in human striatum. Neuropsychopharmacology (2000) 2.28
Dual origins of Finns revealed by Y chromosome haplotype variation. Am J Hum Genet (1998) 2.21
Isolation of a cDNA clone coding for a possible neural nicotinic acetylcholine receptor alpha-subunit. Nature (1986) 2.13
Serotonin transporter missense mutation associated with a complex neuropsychiatric phenotype. Mol Psychiatry (2003) 2.12
Bacterial virus gene expression in human cells. Nature (1971) 2.04
Influence of psychological factors on risk of temporomandibular disorders. J Dent Res (2007) 2.02
Apolipoprotein E epsilon 4 and clinical phenotype in schizophrenia. Lancet (1997) 2.02
Fate of bacteriophage lambda in non-immune germ-free mice. Nature (1973) 1.96
The utility of the non-human primate; model for studying gene by environment interactions in behavioral research. Genes Brain Behav (2003) 1.91
Members of a nicotinic acetylcholine receptor gene family are expressed in different regions of the mammalian central nervous system. Cell (1987) 1.90
Interaction between a functional MAOA locus and childhood sexual abuse predicts alcoholism and antisocial personality disorder in adult women. Mol Psychiatry (2007) 1.88
Variations in expression of mutant beta actin accompanying incremental increases in human fibroblast tumorigenicity. Cell (1982) 1.86
Serotonergic dysfunction, negative mood states, and response to alcohol. Alcohol Clin Exp Res (2001) 1.85
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The A1 allele at the D2 dopamine receptor gene and alcoholism. A reappraisal. JAMA (1993) 1.83
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An Asian-Native American paternal lineage identified by RPS4Y resequencing and by microsatellite haplotyping. Ann Hum Genet (1999) 1.78
The cheetah is depauperate in genetic variation. Science (1983) 1.75
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Population and pedigree studies reveal a lack of association between the dopamine D2 receptor gene and alcoholism. JAMA (1990) 1.51
Bacteriophage K1-5 encodes two different tail fiber proteins, allowing it to infect and replicate on both K1 and K5 strains of Escherichia coli. J Virol (2001) 1.50
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Tetranucleotide repeat polymorphism at the human coagulation factor XIII A subunit gene (F13A1). Nucleic Acids Res (1991) 1.46
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Evidence based case report: treatment for head lice. BMJ (1999) 1.39
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Tetranucleotide repeat polymorphism at the human beta-actin related pseudogene H-beta-Ac-psi-2 (ACTBP2). Nucleic Acids Res (1992) 1.22
Finding the gene(s) for alcoholism. JAMA (1990) 1.21
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Why a peer intervention program for Mexican-American women failed to modify the secular trend in cancer screening. Am J Prev Med (1998) 1.20
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Chromosomal distribution of 320 genes from a brain cDNA library. Nat Genet (1993) 1.19
Mannose-binding protein genetic polymorphisms in black patients with systemic lupus erythematosus. Arthritis Rheum (1996) 1.18
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Evidence for a susceptibility gene for anorexia nervosa on chromosome 1. Am J Hum Genet (2002) 1.17
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Role of the serotonin transporter promoter polymorphism in anxiety-related traits. Arch Gen Psychiatry (1998) 1.16
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Tetranucleotide repeat polymorphism at the human aromatase cytochrome P-450 gene (CYP19). Nucleic Acids Res (1991) 1.15
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