Published in Immunol Rev on January 01, 1981
Successful treatment of autoimmunity in NZB/NZW F1 mice with monoclonal antibody to L3T4. J Exp Med (1985) 3.56
Somatic mutation of the T15 heavy chain gives rise to an antibody with autoantibody specificity. Proc Natl Acad Sci U S A (1984) 3.35
Analysis of T cell function in autoimmune murine strains. Defects in production and responsiveness to interleukin 2. J Exp Med (1981) 3.27
Pathogenesis of systemic lupus erythematosus. J Clin Pathol (2003) 2.93
Systemic autoimmune disease arises from polyclonal B cell activation. J Exp Med (1987) 2.71
Identification of a B cell differentiation factor(s) spontaneously produced by proliferating T cells in murine lupus strains of the lpr/lpr genotype. J Exp Med (1983) 2.15
Influence of thymic genotype on the systemic lupus erythematosus-like disease and T cell proliferation of MRL/Mp-lpr/lpr mice. J Exp Med (1981) 2.07
A new mutation, gld, that produces lymphoproliferation and autoimmunity in C3H/HeJ mice. J Exp Med (1984) 2.06
Induction of murine autoimmune disease by chronic polyclonal B cell activation. J Exp Med (1983) 2.06
Rationale for bone marrow transplantation in the treatment of autoimmune diseases. Proc Natl Acad Sci U S A (1985) 1.97
B cell dependence on and response to accessory signals in murine lupus strains. J Exp Med (1983) 1.79
The contribution of NZW genes to lupus-like disease in (NZB x NZW)F1 mice. J Exp Med (1987) 1.64
Prevention of nephritis in major histocompatibility complex class II-deficient MRL-lpr mice. J Exp Med (1994) 1.61
Antibodies to RNA from autoimmune NZB/NZW mice recognize a similar antigenic determinant and show a large idiotypic diversity. Proc Natl Acad Sci U S A (1982) 1.58
One-way occurrence of graft-versus-host disease in bone marrow chimaeras between congenic MRL mice. Immunology (1984) 1.50
Glomerular type 1 angiotensin receptors augment kidney injury and inflammation in murine autoimmune nephritis. J Clin Invest (2009) 1.41
Interleukin-6 exacerbates glomerulonephritis in (NZB x NZW)F1 mice. Am J Pathol (1994) 1.32
Relationship between systemic lupus erythematosus T cell subsets, anti-T cell antibodies, and T cell functions. J Clin Invest (1984) 1.32
Ability of the xid gene to prevent autoimmunity in (NZB X NZW)F1 mice during the course of their natural history, after polyclonal stimulation, or following immunization with DNA. J Clin Invest (1982) 1.30
Oestrogen is a potent disease accelerator in SLE-prone MRL lpr/lpr mice. Clin Exp Immunol (1990) 1.26
Properties of the ribosomal P2 protein autoantigen are similar to those of foreign protein antigens. Proc Natl Acad Sci U S A (1988) 1.22
Impaired neurotransmitter release from lacrimal and salivary gland nerves of a murine model of Sjögren's syndrome. Invest Ophthalmol Vis Sci (2001) 1.22
Placebo and the new physiology of the doctor-patient relationship. Physiol Rev (2013) 1.20
Induction of cross-reactive anti-dsDNA antibodies in preautoimmune NZB/NZW mice by immunization with bacterial DNA. J Clin Invest (1995) 1.20
Mononuclear-cell pulmonary vasculitis in NZB/W mice. I. Histopathologic evaluation of spontaneously occurring pulmonary infiltrates. Am J Pathol (1985) 1.20
Circulating CSF-1 promotes monocyte and macrophage phenotypes that enhance lupus nephritis. J Am Soc Nephrol (2009) 1.18
Sialadenitis in the MRL-l mouse: morphological and immunohistochemical characterization of resident and infiltrating cells. Immunology (1987) 1.17
Rodent preclinical models for developing novel antiarthritic molecules: comparative biology and preferred methods for evaluating efficacy. J Biomed Biotechnol (2010) 1.16
Oestradiol- and testosterone-mediated effects on the immune system in normal and autoimmune mice are genetically linked and inherited as dominant traits. Immunology (1989) 1.15
Influence of early or late dietary restriction on life span and immunological parameters in MRL/Mp-lpr/lpr mice. Proc Natl Acad Sci U S A (1984) 1.12
Polyclonal B cell activation in lupus-prone mice precedes and predicts the development of autoimmune disease. J Clin Invest (1990) 1.11
Immune dysfunction in diabetes-prone BB rats. Interleukin 2 production and other mitogen-induced responses are suppressed by activated macrophages. J Exp Med (1984) 1.10
Autoimmune diseases: immunopathology and etiopathogenesis. Am J Pathol (1982) 1.07
Monocytosis in the BXSB model for systemic lupus erythematosus. J Exp Med (1984) 1.07
IL-18 cDNA vaccination protects mice from spontaneous lupus-like autoimmune disease. Proc Natl Acad Sci U S A (2003) 1.06
Continuous production of anti-host IgG antibodies contained in circulating IgG-anti-IgG complexes. Immunology (1982) 1.05
Programmed death ligand 1 regulates a critical checkpoint for autoimmune myocarditis and pneumonitis in MRL mice. J Immunol (2008) 1.03
Patterns of autoreactivity to collagen type II in autoimmune MRL/l mice. Clin Exp Immunol (1986) 1.02
Inhibition by restricted-calorie diet of lymphoproliferative disease and renal damage in MRL/lpr mice. Proc Natl Acad Sci U S A (1984) 1.02
Aberrant macrophages mediate defective kidney repair that triggers nephritis in lupus-susceptible mice. J Immunol (2012) 1.02
Monoclonal IgM rheumatoid factors derived from arthritic MRL/Mp-lpr/lpr mice. J Exp Med (1983) 1.01
Analysis of the genetic encoding of oestradiol suppression of delayed-type hypersensitivity in (NZB x NZW) F1 mice. Immunology (1991) 1.00
Increased macrophage colony-stimulating factor in neonatal and adult autoimmune MRL-lpr mice. Am J Pathol (1991) 0.99
Low expression of human histocompatibility leukocyte antigen-DR is associated with hypermethylation of human histocompatibility leukocyte antigen-DR alpha gene regions in B cells from patients with systemic lupus erythematosus. J Clin Invest (1985) 0.99
T-cell antigen-receptor genes in autoimmune mice. Proc Natl Acad Sci U S A (1986) 0.98
Oestradiol suppression of delayed-type hypersensitivity in autoimmune (NZB/NZW)F1 mice is a trait inherited from the healthy NZW parental strain. Immunology (1989) 0.97
Unusual cell surface properties of the T lymphocyte population expanding in MRL/Mp-lpr/lpr mice. Immunology (1982) 0.96
Abnormalities induced by the mutant gene, lpr. Patterns of disease and expression of murine leukemia viruses in SJL/J mice homozygous and heterozygous for lpr. J Exp Med (1985) 0.95
Increased renal thromboxane production in murine lupus nephritis. J Clin Invest (1986) 0.95
Effects of LS-2616 administration upon the autoimmune disease of (NZB x NZW) F1 hybrid mice. Immunology (1986) 0.95
Induction of autoimmunity in normal mice by thymectomy and administration of polyclonal B cell activators: association with contrasuppressor function. Clin Exp Immunol (1983) 0.94
Influence of diet on vascular lesions in autoimmune-prone B/W mice. Proc Natl Acad Sci U S A (1983) 0.91
Studies of defective tolerance induction in NZB mice. Evidence for a marrow pre-T cell defect. J Exp Med (1982) 0.91
Distinct roles of CSF-1 isoforms in lupus nephritis. J Am Soc Nephrol (2011) 0.89
Age-dependent deficiency of B lymphocyte lineage precursors in NZB mice. J Exp Med (1982) 0.89
Mononuclear cell pulmonary vasculitis in NZB/W mice. II. Immunohistochemical characterization of the infiltrating cells. Am J Pathol (1986) 0.89
Pathogenesis of lupus dermatoses in autoimmune mice. IV. Association between cutaneous immunoglobulin deposition and anti-single-stranded DNA antibodies in sera. Arch Dermatol Res (1985) 0.89
Experimental murine and primate models for dissection of the immunosuppressive potential of photochemotherapy in autoimmune disease and transplantation. Yale J Biol Med (1990) 0.88
Detection of neuropeptide Y and its mRNA in megakaryocytes: enhanced levels in certain autoimmune mice. Proc Natl Acad Sci U S A (1987) 0.88
Resistant nature of T cells of autoimmune mice to tolerance induction with human serum albumin. Immunology (1982) 0.88
Suppression of spontaneous murine lupus by inducing graft-versus-host reaction with CD8+ cells. Clin Exp Immunol (1992) 0.87
Tumor necrosis factor sustains the generalized lymphoproliferative disorder (gld) phenotype. J Exp Med (2000) 0.87
Neuroanatomical anomalies in autoimmune mice. Acta Neuropathol (1987) 0.86
Delineation of two defects responsible for T-cell hyporesponsiveness to concanavalin A in MRL congenic mice. Immunology (1986) 0.86
The type of dietary fat affects the severity of autoimmune disease in NZB/NZW mice. Am J Pathol (1987) 0.86
Suppression of nephrotoxic serum nephritis in rats by prostaglandin E1. Am J Pathol (1982) 0.86
Anti-C1q autoantibodies in murine lupus nephritis. Clin Exp Immunol (2004) 0.86
Effect of FUT-175, a new synthetic protease inhibitor, on the development of lupus nephritis in (NZB x NZW) F1 mice. Immunology (1985) 0.83
Interaction between glutathione and apoptosis in systemic lupus erythematosus. Autoimmun Rev (2012) 0.83
Role of MHC-linked susceptibility genes in the pathogenesis of human and murine lupus. Clin Dev Immunol (2012) 0.83
Dexamethasone prevents autoimmune nephritis and reduces renal expression of Ia but not costimulatory signals. Am J Pathol (1992) 0.82
Genetics of experimental lupus nephritis: non-H-2 factors determine susceptibility for renal involvement in murine chronic graft-versus-host disease. Clin Exp Immunol (1989) 0.82
The effects of CP 17193, an immunosuppressive pyrazaloquinoline, on the development of spontaneous lupus disease in NZBW F1 hybrid mice. Clin Exp Immunol (1992) 0.82
Effects of dietary supplementation on autoimmunity in the MRL/lpr mouse: a preliminary investigation. Ann Rheum Dis (1986) 0.80
Cytotoxic T lymphocytes reactive against a syngeneic murine tumor and their specific suppressor T cells are both elicited by in vitro allosensitization. J Exp Med (1990) 0.80
Detection of inhibition of 5-aminoimidazole-4-carboxamide ribotide transformylase by thioinosinic acid and azathioprine by a new colorimetric assay. Biochem J (1990) 0.80
Aberrant production of leukotriene C4 by macrophages from autoimmune-prone mice. J Exp Med (1988) 0.80
Increased vascular permeability in the thymus of the autoimmune New Zealand mouse. J Anat (1988) 0.79
Mycobacteria-induced autoantibody production is associated with susceptibility to infection but not with host propensity to develop autoimmune disease. Clin Exp Immunol (1995) 0.79
Proliferation of CD3+ B220- single-positive normal T cells was suppressed in B-cell-deficient lpr mice. Immunology (1998) 0.79
Role of endogenous 4-1BB in the development of systemic lupus erythematosus. Immunology (2007) 0.79
Induction of mucosal tolerance in SLE: a sniff or a sip away from ameliorating lupus? Clin Immunol (2008) 0.79
Combined effects of FK506 (tacrolimus) and cyclophosphamide on atypical B220+ T cells, cytokine gene expression and disease activity in MRL/MpJ-lpr/lpr mice. Clin Exp Immunol (1995) 0.79
Murine lupus nephritis: effect of azathioprine on glomerular permeability and localization of immunoreactants. Clin Exp Immunol (1983) 0.78
Induction of immunoglobulin-secreting cells by 2-mercaptoethanol in in vitro culture of B cells from autoimmune mice. Immunology (1984) 0.78
Different expression of T-cell receptor beta-chain variable region genes in lymph nodes of lpr mice with different alleles of the major histocompatibility complex. Immunology (1990) 0.78
Studies on the role of the lpr gene in the development of immunological abnormalities and lupus nephritis. Analyses in F2 mice. Clin Exp Immunol (1985) 0.78
Lupus Nephritis: Animal Modeling of a Complex Disease Syndrome Pathology. Drug Discov Today Dis Models (2014) 0.78
Murine splenic null cell compartment contains distinct haemopoietic subpopulations: enlargement of a myeloid and an undifferentiated subset with the development of splenomegaly in New Zealand black mice. Immunology (1992) 0.77
Analysis of autoantibodies to glycolipids on thymocytes in New Zealand black mice. Immunology (1989) 0.77
Frequency and phenotypic feature of autoantibody-producing cell precursors in the preclinical stage of murine lupus. Immunology (1990) 0.77
Alpha 1 Antitrypsin Inhibits Dendritic Cell Activation and Attenuates Nephritis in a Mouse Model of Lupus. PLoS One (2016) 0.77
Immunosuppressive effects of (2R,5R)-6-heptyne-2,5-diamine, an inhibitor of polyamine synthesis: II. Beneficial effects on the development of a lupus-like disease in MRL-lpr/lpr mice. Clin Exp Immunol (1988) 0.77
Abnormal rearrangements of T-cell receptor genes occur in long-term cultured bone marrow cells of lpr/lpr mice. Immunology (1989) 0.76
Evaluation of a model for post-partum arthritis and the role of oestrogen in prevention of MRL-lpr associated rheumatic conditions. Clin Exp Immunol (1994) 0.76
Antigen-specific T-cell hyporesponsiveness in MRL congenic mice can be explained by two independent cellular defects. Immunology (1987) 0.75
Tissue graft rejection in murine models of autoimmune disease. Clin Exp Immunol (1983) 0.75
Treatment of autoimmune MRL/Mp-lpr/lpr mice with cholera toxin. Clin Exp Immunol (1987) 0.75
Abnormalities of third-order suppressor T cells in old (New Zealand black x New Zealand white) F1 mice. Immunology (1984) 0.75
Sensitivity of pre-T cells to natural thymocytotoxic autoantibodies developed in New Zealand Black mice. Clin Exp Immunol (1982) 0.75
A method of trace iodination of proteins for immunologic studies. Int Arch Allergy Appl Immunol (1966) 43.66
Spontaneous murine lupus-like syndromes. Clinical and immunopathological manifestations in several strains. J Exp Med (1978) 11.99
Murine models of systemic lupus erythematosus. Adv Immunol (1985) 9.79
Pathogenesis of the glomerulonephritis of NZB/W mice. J Exp Med (1968) 8.91
The Raji cell radioimmune assay for detecting immune complexes in human sera. J Clin Invest (1976) 8.06
The role of anti-glomerular basement membrane antibody in the pathogenesis of human glomerulonephritis. J Exp Med (1967) 6.81
Pathogenesis of chronic disease associated with persistent lymphocytic choriomeningitis viral infection. I. Relationship of antibody production to disease in neonatally infected mice. J Exp Med (1969) 6.03
Autologous immune complex nephritis induced with renal tubular antigen. I. Identification and isolation of the pathogenetic antigen. J Exp Med (1968) 4.79
Shwartzman reaction after human renal homotransplantation. N Engl J Med (1968) 4.05
Lymphocytic choriomeningitis: production of antibody by "tolerant" infected mice. Science (1967) 4.01
Autologous immune-complex pathogenesis of experimental allergic glomerulonephritis. Science (1967) 3.96
Circulating immune complexes in the idiopathic interstitial pneumonias. N Engl J Med (1978) 3.83
Experimental glomerulonephritis: immunological events and pathogenetic mechanisms. Adv Immunol (1967) 3.83
Increased spontaneous polyclonal activation of B lymphocytes in mice with spontaneous autoimmune disease. J Immunol (1978) 3.78
Serum transfer of collagen-induced arthritis in mice. J Exp Med (1983) 3.74
The pathogenesis of glomerulonephritis. Am J Med (1968) 3.61
Presence of anti-Sm reactivity in autoimmune mouse strains. J Exp Med (1978) 3.58
Endogenous oncornaviral gene expression in adult and fetal mice: quantitative, histologic, and physiologic studies of the major viral glycorprotein, gp70. J Exp Med (1976) 3.51
Autologous immune complex nephritis induced with renal tubular antigen. II. The pathogenetic mechanism. J Exp Med (1968) 3.40
The effect of passively administered antibody on antibody synthesis. J Exp Med (1967) 3.31
Analysis of T cell function in autoimmune murine strains. Defects in production and responsiveness to interleukin 2. J Exp Med (1981) 3.27
Anti-glomerular basement membrane antibody-induced glomerulonephritis. Kidney Int (1973) 3.09
The biology and detection of immune complexes. Adv Immunol (1979) 3.05
IgM rheumatoid factors in mice injected with bacterial lipopolysaccharides. J Immunol (1979) 2.86
Association of circulating retroviral gp70-anti-gp70 immune complexes with murine systemic lupus erythematosus. J Exp Med (1979) 2.86
A spontaneous rheumatoid arthritis-like disease in MRL/l mice. J Exp Med (1982) 2.76
The potential pathogenic role of complement in dengue hemorrhagic shock syndrome. N Engl J Med (1973) 2.64
Mechanism and modification of rejection of heterografts between divergent species. Transplant Proc (1970) 2.63
Interferon-gamma is required for lupus-like disease and lymphoaccumulation in MRL-lpr mice. J Clin Invest (1998) 2.60
Distribution of lymphocytes identified by surface markers in murine strains with systemic lupus erythematosus-like syndromes. J Exp Med (1979) 2.55
The antibody response of mice to murine leukemia virus in spontaneous infection: absence of classical immunologic tolerance (AKR mice-complement-fixing antibodies-lymphocytic choriomeningitis virus-immunofluorescence-glomerular deposits of antigen-antibody complexes). Proc Natl Acad Sci U S A (1972) 2.54
Binding of soluble immune complexes to human lymphoblastoid cells. II. Use of Raji cells to detect circulating immune complexes in animal and human sera. J Exp Med (1974) 2.51
IgM rheumatoid factor and low molecular weight IgM. An association with vasculitis. Arthritis Rheum (1974) 2.45
Transfer of ovine experimental allergic glomerulonephritis (EAG) with serum. J Exp Med (1966) 2.42
Histocompatibility-linked genetic control of disease susceptibility. Murine lymphocytic choriomeningitis virus infection. J Exp Med (1973) 2.39
Humoral antibodies and coagulation mechanisms in the accelerated or hyperacute rejection of renal homografts in sensitized canine recipients. Surgery (1970) 2.38
The oncornavirus glycoprotein gp69/71: a constituent of the surface of normal and malignant thymocytes. J Exp Med (1975) 2.37
Clotting changes, including disseminated intravascular coagulation, during rapid renal-homograft rejection. N Engl J Med (1970) 2.33
Isolation of human T and B lymphocytes by rosette formation with 2-aminoethylisothiquronium bromide (AET) -treated sheep red blood cells with monkey red blood cells. J Immunol Methods (1976) 2.30
Characterization and isolation of specific renal tubular epithelial antigens. J Immunol (1967) 2.25
Binding of soluble immune complexes to human lymphoblastoid cells. I. Characterization of receptors for IgG Fc and complement and description of the binding mechanism. J Exp Med (1974) 2.22
The effect of induced chronic viral infections on the immunologic diseases of New Zealand mice. J Exp Med (1970) 2.16
Identification of a B cell differentiation factor(s) spontaneously produced by proliferating T cells in murine lupus strains of the lpr/lpr genotype. J Exp Med (1983) 2.15
Immunopathogenicity and oncogenicity of murine leukemia viruses. I. Induction of immunologic disease and lymphoma in (BALB-c times NZB)F1 mice by Scripps leukemia virus. J Exp Med (1974) 2.12
Lupus susceptibility loci in New Zealand mice. Proc Natl Acad Sci U S A (1994) 2.12
Immunohistochemical study of allergic encephalomyelitis. Am J Pathol (1968) 2.10
Pathogenesis of the slow disease of the central nervous system associated with WM 1504 E virus. I. Relationship of strain susceptibility and replication to disease. Am J Pathol (1977) 2.08
Influence of thymic genotype on the systemic lupus erythematosus-like disease and T cell proliferation of MRL/Mp-lpr/lpr mice. J Exp Med (1981) 2.07
Diagnosis of immunopathologic renal disease. Kidney Int (1974) 2.07
Splenic immunoglobulin-secreting cells and their regulation in autoimmune mice. J Exp Med (1980) 2.07
Induction of murine autoimmune disease by chronic polyclonal B cell activation. J Exp Med (1983) 2.06
Circulating immune complexes in infective endocarditis. N Engl J Med (1976) 2.02
Radioiodination of proteins by the use of the chloramine-T method. Methods Enzymol (1980) 2.01
Tissue injury in lymphocytic choriomeningitis viral infection: virus-induced immunologically specific release of a cytotoxic factor from immune lymphoid cells. Virology (1970) 2.00
Immune response to a hapten coupled to a nonimmunogenic carrier. Influence of lipopolysaccharide. J Exp Med (1972) 1.95
Antigen quantitation in experimental immune complex glomerulonephritis. I. Acute serum sickness. J Immunol (1970) 1.93
Genesis and evolution of antichromatin autoantibodies in murine lupus implicates T-dependent immunization with self antigen. J Clin Invest (1993) 1.92
Receptor for soluble C3 and C3b on human lymphoblastoid (RAJI) cells. Properties and biologocal significance. J Exp Med (1974) 1.91
Experimental allergic glomerulonephritis induced in the rabbit with heterologous renal antigens. J Exp Med (1967) 1.90
The nature of immune complexes in human cancer sera. J Immunol (1977) 1.88
The pathogenic effect of IgG4 autoantibodies in endemic pemphigus foliaceus (fogo selvagem). N Engl J Med (1989) 1.88
Comparison of the immune responsiveness of NZB and NZB X NZW F1 hybrid mice with that of other strains of mice. J Exp Med (1969) 1.87
Tolerance-related V beta clonal deletions in normal CD4-8-, TCR-alpha/beta + and abnormal lpr and gld cell populations. J Exp Med (1989) 1.83
Analysis of vascular lesions in murine SLE. I. Association with serologic abnormalities. J Immunol (1983) 1.81
B cell dependence on and response to accessory signals in murine lupus strains. J Exp Med (1983) 1.79
Replication of dengue-2 virus in cultured human lymphoblastoid cells and subpopulations of human peripheral leukocytes. J Immunol (1976) 1.79
Experimental allergic glomerulonephritis induced in the rabbit with homologous renal antigens. J Exp Med (1967) 1.76
The antibody responses of rabbits and rats to hemocyanin. J Immunol (1966) 1.75
Quantitation of acute and chronic serum sickness in the rabbit. J Exp Med (1971) 1.74
Characterization of human anti-glomerular basement membrane antibodies eluted from glomerulonephritic kidneys. J Clin Invest (1970) 1.70
Immune complex disease in chronic viral infections. J Exp Med (1971) 1.69
The induction of acute glomerulonephritis in rabbits with soluble antigens isolated from normal homologous and autologous urine. J Immunol (1968) 1.68
Detection of circulating immune complexes in patients with glomerulonephritis. Kidney Int (1977) 1.66
Loci predisposing to autoimmunity in MRL-Fas lpr and C57BL/6-Faslpr mice. J Clin Invest (1998) 1.65
Karyotypic, virologic, and immunologic analyses of two continuous lymphocyte lines established from New Zealand black mice: possible relationship of chromosomal mosaicism to autoimmunity. Proc Natl Acad Sci U S A (1972) 1.65
Transfer of human systemic lupus erythematosus in severe combined immunodeficient (SCID) mice. J Exp Med (1990) 1.61
Genesis of antinuclear antibody in NZB-W mice: role of genetic factors and of viral infections. Clin Exp Immunol (1970) 1.59
Use of bovine conglutinin for the assay of immune complexes. J Immunol (1977) 1.56
Association of lpr gene with graft-vs.-host disease-like syndrome. J Exp Med (1985) 1.56