Published in J Neurochem on July 01, 1982
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Colocalization of cholinesterases with beta amyloid protein in aged and Alzheimer's brains. Acta Neuropathol (1993) 0.91
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Identification of neural profiles containing vasoactive intestinal polypeptide, acetylcholinesterase and catecholamines in the rat thymus. J Anat (1991) 0.84
Cholinesterases colocalize with sites of neurofibrillary degeneration in aged and Alzheimer's brains. Acta Neuropathol (1994) 0.80
Complete amino acid sequence of human serum cholinesterase. J Biol Chem (1987) 2.66
Structure of the gene for human butyrylcholinesterase. Evidence for a single copy. Biochemistry (1990) 2.26
Comparison of butyrylcholinesterase and acetylcholinesterase. Biochem J (1989) 1.77
Predicted Michaelis-Menten complexes of cocaine-butyrylcholinesterase. Engineering effective butyrylcholinesterase mutants for cocaine detoxication. J Biol Chem (2000) 1.64
Role of aspartate 70 and tryptophan 82 in binding of succinyldithiocholine to human butyrylcholinesterase. Biochemistry (1997) 1.59
Identification of the structural mutation responsible for the dibucaine-resistant (atypical) variant form of human serum cholinesterase. Proc Natl Acad Sci U S A (1989) 1.56
An improved cocaine hydrolase: the A328Y mutant of human butyrylcholinesterase is 4-fold more efficient. Mol Pharmacol (1999) 1.46
Abundant tissue butyrylcholinesterase and its possible function in the acetylcholinesterase knockout mouse. J Neurochem (2000) 1.44
Acetylcholinesterase knockouts establish central cholinergic pathways and can use butyrylcholinesterase to hydrolyze acetylcholine. Neuroscience (2002) 1.41
Brain cDNA clone for human cholinesterase. Proc Natl Acad Sci U S A (1987) 1.39
DNA mutation associated with the human butyrylcholinesterase K-variant and its linkage to the atypical variant mutation and other polymorphic sites. Am J Hum Genet (1992) 1.36
Design and expression of organophosphorus acid anhydride hydrolase activity in human butyrylcholinesterase. Biochemistry (1995) 1.31
Interaction between the peripheral site residues of human butyrylcholinesterase, D70 and Y332, in binding and hydrolysis of substrates. Biochim Biophys Acta (1999) 1.28
Studies on the mechanism of action of the flavoenzyme lactate oxidase. Oxidation and elimination with beta-chlorolactate. J Biol Chem (1973) 1.25
Inactivation of a flavoprotein, lactate oxidase, by an acetylenic substrate. J Biol Chem (1972) 1.22
Mechanism of action of the flavoenzyme lactate oxidase. J Biol Chem (1972) 1.20
The cloning and expression of a gene encoding Old Yellow Enzyme from Saccharomyces carlsbergensis. J Biol Chem (1991) 1.18
Reconsideration of the catalytic center and mechanism of mammalian paraoxonase/arylesterase. Proc Natl Acad Sci U S A (1995) 1.17
Postnatal developmental delay and supersensitivity to organophosphate in gene-targeted mice lacking acetylcholinesterase. J Pharmacol Exp Ther (2000) 1.14
Evidence for nonacetylcholinesterase targets of organophosphorus nerve agent: supersensitivity of acetylcholinesterase knockout mouse to VX lethality. J Pharmacol Exp Ther (2001) 1.13
Association of tetramers of human butyrylcholinesterase is mediated by conserved aromatic residues of the carboxy terminus. Chem Biol Interact (1999) 1.12
Tetramerization domain of human butyrylcholinesterase is at the C-terminus. Biochem J (1997) 1.12
Organophosphorus acid anhydride hydrolase activity in human butyrylcholinesterase: synergy results in a somanase. Biochemistry (1998) 1.10
Comparison of atypical and usual human serum cholinesterase. Purification, number of active sites, substrate affinity, and turnover number. J Biol Chem (1978) 1.08
Differences in active site gorge dimensions of cholinesterases revealed by binding of inhibitors to human butyrylcholinesterase. Biochemistry (1997) 1.07
Identification of residues essential for human paraoxonase (PON1) arylesterase/organophosphatase activities. Biochemistry (1999) 1.06
Importance of aspartate-70 in organophosphate inhibition, oxime re-activation and aging of human butyrylcholinesterase. Biochem J (1997) 1.06
Hydrolysis of diacetylmorphine (heroin) by human serum cholinesterase. J Pharmacol Exp Ther (1980) 1.06
Identification of a frameshift mutation responsible for the silent phenotype of human serum cholinesterase, Gly 117 (GGT----GGAG). Am J Hum Genet (1990) 1.02
Asp7O in the peripheral anionic site of human butyrylcholinesterase. Eur J Biochem (1996) 1.00
Interchain disulfide bonds and subunit organization in human serum cholinesterase. J Biol Chem (1979) 0.96
Conserved aromatic residues of the C-terminus of human butyrylcholinesterase mediate the association of tetramers. Biochemistry (1999) 0.95
Use of the polymerase chain reaction for homology probing of butyrylcholinesterase from several vertebrates. J Biol Chem (1991) 0.95
Proposed nomenclature for human butyrylcholinesterase genetic variants identified by DNA sequencing. Cell Mol Neurobiol (1991) 0.95
The active site of human paraoxonase (PON1). J Appl Toxicol (2001) 0.94
Bacterial expression and in vitro folding of the beta-subunit of human chorionic gonadotropin (hCG beta) and functional assembly of recombinant hCG beta with hCG alpha. Endocrinology (1994) 0.92
The cloned butyrylcholinesterase (BCHE) gene maps to a single chromosome site, 3q26. Genomics (1991) 0.92
Protein engineering of a human enzyme that hydrolyzes V and G nerve agents: design, construction and characterization. Chem Biol Interact (1999) 0.91
Amino acid sequence of the active site of human serum cholinesterase from usual, atypical, and atypical-silent genotypes. Biochem Genet (1986) 0.90
Argininosuccinate synthetase activity in cultured human lymphocytes. Biochem Genet (1977) 0.89
Phenotypic and molecular biological analysis of human butyrylcholinesterase variants. Clin Biochem (1990) 0.88
Immunological comparison of the usual and atypical human serum cholinesterase phenotypes. Biochem Genet (1983) 0.87
The pH dependence of dealkylation in soman-inhibited cholinesterases and their mutants: further evidence for a push-pull mechanism. Biochemistry (1998) 0.87
Aging of di-isopropyl-phosphorylated human butyrylcholinesterase. Biochem J (1997) 0.87
Mutation at codon 322 in the human acetylcholinesterase (ACHE) gene accounts for YT blood group polymorphism. Am J Hum Genet (1993) 0.87
Butyrylcholinesterase-catalysed hydrolysis of aspirin, a negatively charged ester, and aspirin-related neutral esters. Biochim Biophys Acta (1998) 0.86
Recombinant human butyrylcholinesterase G390V, the fluoride-2 variant, expressed in Chinese hamster ovary cells, is a low affinity variant. J Biol Chem (1993) 0.85
Promoter and transcription start site of human and rabbit butyrylcholinesterase genes. J Biol Chem (1994) 0.85
Enzymes hydrolyzing organophosphates as potential catalytic scavengers against organophosphate poisoning. J Physiol Paris (1999) 0.85
Differences in active-site gorge dimensions of cholinesterases revealed by binding of inhibitors to human butyrylcholinesterase. Chem Biol Interact (1999) 0.85
Tissue distribution of human acetylcholinesterase and butyrylcholinesterase messenger RNA. Toxicon (1994) 0.85
Effects of mutations of active site residues and amino acids interacting with the Omega loop on substrate activation of butyrylcholinesterase. Biochim Biophys Acta (2001) 0.83
Determination of the DNA sequences of acetylcholinesterase and butyrylcholinesterase from cat and demonstration of the existence of both in cat plasma. Biochem Pharmacol (2000) 0.83
The butyrylcholinesterase K-variant shows similar cellular protein turnover and quaternary interaction to the wild-type enzyme. J Neurochem (2000) 0.83
Adenovirus-mediated human paraoxonase1 gene transfer to provide protection against the toxicity of the organophosphorus pesticide toxicant diazoxon. Gene Ther (2010) 0.82
Molecular biology of human serum cholinesterase. Fed Proc (1986) 0.82
Knockout of one acetylcholinesterase allele in the mouse. Chem Biol Interact (1999) 0.82
Loss of the interchain disulfide peptide and dissociation of the tetramer following limited proteolysis of native human serum cholinesterase. J Biol Chem (1982) 0.82
Identification of two different point mutations associated with the fluoride-resistant phenotype for human butyrylcholinesterase. Am J Hum Genet (1992) 0.81
Protein folding and assembly in vitro parallel intracellular folding and assembly. Catalysis of folding and assembly of the human chorionic gonadotropin alpha beta dimer by protein disulfide isomerase. J Biol Chem (1993) 0.80
Human serum paraoxonase (PON1): identification of essential amino acid residues by group-selective labelling and site-directed mutagenesis. Chem Biol Interact (1999) 0.80
Structure of human serum cholinesterase. Bioessays (1988) 0.79
Comparison of cognitive functions between people with silent and wild-type butyrylcholinesterase. J Neural Transm (Vienna) (2007) 0.79
Polyol-induced activation by excess substrate of the D70G butyrylcholinesterase mutant. Biochim Biophys Acta (1999) 0.79
Resistance of butyrylcholinesterase to inactivation by ultrasound: effects of ultrasound on catalytic activity and subunit association. Biochim Biophys Acta (1998) 0.79
Hydrolysis of methylprednisolone acetate by human serum cholinesterase. Drug Metab Dispos (1982) 0.78
Evidence for a single butyrylcholinesterase gene in individuals carrying the C5 plasma cholinesterase variant (CHE2). FEBS Lett (1990) 0.78
Endogenous butyrylcholinesterase in SV40 transformed cell lines: COS-1, COS-7, MRC-5 SV40, and WI-38 VA13. In Vitro Cell Dev Biol Anim (1994) 0.78
Citrulline metabolism in normal and citrullinemic human lymphocyte lines. Biochem Genet (1975) 0.78
The butyrylcholinesterase gene (BCHE) at 3q26.2 shows two RFLPs. Nucleic Acids Res (1991) 0.78
Structural and hydration changes in the active site gorge of phosporhylated butyrylcholinesterase accompanying the aging process. Chem Biol Interact (1999) 0.78
Prediction of drug sensitivity in individuals with atypical serum cholinesterase based on in vitro biochemical studies. Biochem Pharmacol (1981) 0.77
Tryptophan residue(s) as major components of the human serum paraoxonase active site. Chem Biol Interact (1999) 0.77
Mutation His322Asn in human acetylcholinesterase does not alter electrophoretic and catalytic properties of the erythrocyte enzyme. Blood (1994) 0.76
Prolonged apnea following trimethaphan and succinylcholine. Anesthesiology (1979) 0.75
Prolonged paralysis after a test dose of mivacurium in a patient with atypical serum cholinesterase. Anesth Analg (1998) 0.75
Structural data on the aging of diethylphosphoryl-butyrylcholinesterase. Chem Biol Interact (2005) 0.75