Published in J Immunol on July 01, 1984
Somatic mutation of the T15 heavy chain gives rise to an antibody with autoantibody specificity. Proc Natl Acad Sci U S A (1984) 3.35
Origins of anti-DNA autoantibodies. J Clin Invest (1985) 2.26
Nascent RNA cleavage by arrested RNA polymerase II does not require upstream translocation of the elongation complex on DNA. J Biol Chem (1993) 1.75
Immunochemical similarities between monoclonal antibacterial Waldenstrom's macroglobulins and monoclonal anti-DNA lupus autoantibodies. J Exp Med (1985) 1.49
Homology of the NH2-terminal amino acid sequences of the heavy and light chains of human monoclonal lupus autoantibodies containing the dominant 16/6 idiotype. J Clin Invest (1985) 1.26
Genetic elements used for a murine lupus anti-DNA autoantibody are closely related to those for antibodies to exogenous antigens. J Exp Med (1985) 1.23
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Analysis of anticentromere autoantibodies using cloned autoantigen CENP-B. Proc Natl Acad Sci U S A (1987) 1.20
Use of on-section immunolabeling and cryosubstitution for studies of bacterial DNA distribution. J Bacteriol (1987) 1.20
Anti-DNA antibodies: problems in their study and interpretation. Clin Exp Immunol (1986) 1.13
Characterization of somatically mutated S107 VH11-encoded anti-DNA autoantibodies derived from autoimmune (NZB x NZW)F1 mice. J Exp Med (1991) 1.10
Somatic diversification of the S107 (T15) VH11 germ-line gene that encodes the heavy-chain variable region of antibodies to double-stranded DNA in (NZB x NZW)F1 mice. Proc Natl Acad Sci U S A (1988) 1.07
Antigen-binding specificities of antibodies are primarily determined by seven residues of VH. Proc Natl Acad Sci U S A (1985) 1.06
In vivo clearance and tissue uptake of an anti-DNA monoclonal antibody and its complexes with DNA. Clin Exp Immunol (1985) 1.05
Somatic diversification of S107 from an antiphosphocholine to an anti-DNA autoantibody is due to a single base change in its heavy chain variable region. Proc Natl Acad Sci U S A (1987) 1.05
Evaluation of the cross-reaction between anti-DNA and anti-cardiolipin antibodies in SLE and experimental animals. Clin Exp Immunol (1986) 1.04
Antibodies elicited by pneumococcal antigens bear an anti-DNA--associated idiotype. J Clin Invest (1991) 1.00
Ig heavy chain variable region gene complex of lupus mice exhibits normal restriction fragment length polymorphism. J Exp Med (1985) 0.96
Induction of severe autoimmune disease in normal mice by simultaneous action of multiple immunostimulators. J Exp Med (1985) 0.95
Splicing components are excluded from the transcriptionally inactive XY body in male meiotic nuclei. Mol Biol Cell (1994) 0.92
A monoclonal DNA-binding autoantibody causes a deterioration in renal function in MRL mice with lupus disease. Clin Exp Immunol (1988) 0.86
VH gene expression is restricted in anti-IgG antibodies from MRL autoimmune mice. J Exp Med (1986) 0.84
Ultrastructural localization of DNA in immune deposits of human lupus nephritis. Am J Pathol (1993) 0.82
Antibody binding of macromolecular DNA and RNA in the plasma of SLE patients. Clin Exp Immunol (1989) 0.82
B cell tolerance and positive selection in lupus. J Immunol (2012) 0.80
Specific inhibition of the DNA-anti-DNA immune reaction by low molecular weight anionic compounds. Immunology (1988) 0.80
Serum monoclonal antibodies derived from patients with multiple myeloma react with mycobacterial phosphoinositides and nuclear antigens. Clin Exp Immunol (1989) 0.78
Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association. Arthritis Rheum (1986) 29.12
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Molecular cloning and expression of cDNAs for the human interleukin-2 receptor. Nature (1984) 7.37
Atlas of individual radiographic features in osteoarthritis. Osteoarthritis Cartilage (1995) 7.18
Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor. Science (1995) 6.03
Purification and characterization of a newly identified growth factor specific for epithelial cells. Proc Natl Acad Sci U S A (1989) 5.10
OARSI recommendations for the management of hip and knee osteoarthritis, part I: critical appraisal of existing treatment guidelines and systematic review of current research evidence. Osteoarthritis Cartilage (2007) 4.34
OMERACT-OARSI initiative: Osteoarthritis Research Society International set of responder criteria for osteoarthritis clinical trials revisited. Osteoarthritis Cartilage (2004) 4.01
Evaluation of clinically relevant changes in patient reported outcomes in knee and hip osteoarthritis: the minimal clinically important improvement. Ann Rheum Dis (2004) 3.95
The three-dimensional structure of a phosphorylcholine-binding mouse immunoglobulin Fab and the nature of the antigen binding site. Proc Natl Acad Sci U S A (1974) 3.92
Genetics of a new IgVH (T15 idiotype) marker in the mouse regulating natural antibody to phosphorylcholine. J Exp Med (1974) 3.64
Design and conduct of clinical trials in patients with osteoarthritis: recommendations from a task force of the Osteoarthritis Research Society. Results from a workshop. Osteoarthritis Cartilage (1996) 3.26
Tritium labeling of proteins to high specific radioactivity by reduction methylation. J Biol Chem (1980) 3.04
Aryl-hydrocarbon receptor-deficient mice are resistant to 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced toxicity. Toxicol Appl Pharmacol (1996) 3.01
The two-component, ATP-dependent Clp protease of Escherichia coli. Purification, cloning, and mutational analysis of the ATP-binding component. J Biol Chem (1988) 2.95
Harnessing optical forces in integrated photonic circuits. Nature (2008) 2.90
Meniscal tear and extrusion are strongly associated with progression of symptomatic knee osteoarthritis as assessed by quantitative magnetic resonance imaging. Ann Rheum Dis (2004) 2.89
Self-regulation of growth in three dimensions. J Exp Med (1973) 2.87
Sequence and structure of Clp P, the proteolytic component of the ATP-dependent Clp protease of Escherichia coli. J Biol Chem (1990) 2.71
Evaluation of clinically relevant states in patient reported outcomes in knee and hip osteoarthritis: the patient acceptable symptom state. Ann Rheum Dis (2004) 2.60
Neoplastic transformation of mast cells by Abelson-MuLV: abrogation of IL-3 dependence by a nonautocrine mechanism. Cell (1985) 2.59
Upper gastrointestinal tract safety profile of alendronate: the fracture intervention trial. Arch Intern Med (2000) 2.46
B cell development under the condition of allelic inclusion. Immunity (1997) 2.39
Purification and molecular cloning of a secreted, Frizzled-related antagonist of Wnt action. Proc Natl Acad Sci U S A (1997) 2.36
The role of pain and functional impairment in the decision to recommend total joint replacement in hip and knee osteoarthritis: an international cross-sectional study of 1909 patients. Report of the OARSI-OMERACT Task Force on total joint replacement. Osteoarthritis Cartilage (2010) 2.24
The Genetics of Generalized Osteoarthritis (GOGO) study: study design and evaluation of osteoarthritis phenotypes. Osteoarthritis Cartilage (2006) 2.01
VH genes encoding the immune response to beta-(1,6)-galactan: somatic mutation in IgM molecules. EMBO J (1984) 1.98
The galactan-binding immunoglobulin Fab J539: an X-ray diffraction study at 2.6-A resolution. Proteins (1986) 1.96
Immunoglobulin structure: amino terminal sequences of mouse myeloma proteins that bind phosphorylcholine. Science (1974) 1.94
Classification of mouse VK groups based on the partial amino acid sequence to the first invariant tryptophan: impact of 14 new sequences from IgG myeloma proteins. Mol Immunol (1982) 1.93
Acupuncture for osteoarthritis of the knee: a systematic review. Arthritis Rheum (2001) 1.91
A hybridoma from an autoimmune NZB/NZW mouse producing monoclonal antibody to ribosomal-RNA. J Immunol (1980) 1.91
Structural evidence for independent joining region gene in immunoglobulin heavy chains from anti-galactan myeloma proteins and its potential role in generating diversity in complementarity-determining regions. Proc Natl Acad Sci U S A (1979) 1.89
Anti-DNA antibodies bind directly to renal antigens and induce kidney dysfunction in the isolated perfused rat kidney. J Immunol (1989) 1.86
Morbidity of systemic lupus erythematosus: role of race and socioeconomic status. Am J Med (1991) 1.79
Knee pain and knee osteoarthritis severity in self-reported task specific disability: the Johnston County Osteoarthritis Project. J Rheumatol (1997) 1.71
Randomized trial of IV dexamethasone for acute migraine in the emergency department. Neurology (2007) 1.64
Etanercept for the treatment of rheumatoid arthritis. Cochrane Database Syst Rev (2003) 1.63
Structural basis for the specificity of phosphorylcholine-binding immunoglobulins. Immunochemistry (1976) 1.63
Nucleic acid and protein sequences of phosphocholine-binding light chains. J Exp Med (1981) 1.61
A randomized trial of acupuncture as an adjunctive therapy in osteoarthritis of the knee. Rheumatology (Oxford) (1999) 1.60
Structure at 4.5 A resolution of a phosphorylcholine-binding fab. Nat New Biol (1973) 1.60
Somatic diversification of immunoglobulins. Proc Natl Acad Sci U S A (1984) 1.59
Antibodies to RNA from autoimmune NZB/NZW mice recognize a similar antigenic determinant and show a large idiotypic diversity. Proc Natl Acad Sci U S A (1982) 1.58
Radiographically defined osteoarthritis of the hand and knee in young and middle-aged African American and Caucasian women. Osteoarthritis Cartilage (2000) 1.55
Purification and NH2-terminal sequence of a plasmacytoma growth factor derived from the murine macrophage cell line P388D1. J Immunol (1987) 1.55
Definition, incidence, and clinical description of flare in systemic lupus erythematosus. A prospective cohort study. Arthritis Rheum (1991) 1.52
Interleukin 6 is essential for in vivo development of B lineage neoplasms. J Exp Med (1995) 1.49
Lupus anti-DNA autoantibodies cross-react with a glomerular structural protein: a case for tissue injury by molecular mimicry. Eur J Immunol (2001) 1.46
Single amino acid substitution altering antigen-binding specificity. Proc Natl Acad Sci U S A (1982) 1.46
Spectral changes on binding of oligosaccharides to murine immunoglobulin A myeloma proteins. Biochemistry (1973) 1.45
Emergency operation after failed angioplasty. J Thorac Cardiovasc Surg (1988) 1.44
Low back pain and disability in older women: independent association with difficulty but not inability to perform daily activities. J Gerontol A Biol Sci Med Sci (1999) 1.44
Clinical decisions in the use of acupuncture as an adjunctive therapy for osteoarthritis of the knee. Altern Ther Health Med (2001) 1.44
Outcome measures and classification criteria for the rheumatic diseases. A compilation of data from OMERACT (Outcome Measures for Arthritis Clinical Trials), ILAR (International League of Associations for Rheumatology), regional leagues and other groups. Rheumatology (Oxford) (2001) 1.41
In vivo induction of IL-6 by administration of exogenous cytokines and detection of de novo serum levels of IL-6 in tumor-bearing mice. J Immunol (1989) 1.41
Reliability of a quantification imaging system using magnetic resonance images to measure cartilage thickness and volume in human normal and osteoarthritic knees. Osteoarthritis Cartilage (2003) 1.41
Minimum clinically important improvement and patient acceptable symptom state in pain and function in rheumatoid arthritis, ankylosing spondylitis, chronic back pain, hand osteoarthritis, and hip and knee osteoarthritis: Results from a prospective multinational study. Arthritis Care Res (Hoboken) (2012) 1.40
Interleukin-2-mediated modulation of plasma cell tumor growth in a model of multiple myeloma. Hum Gene Ther (1998) 1.39
Somatic mutation in a cultured mouse myeloma cell affects antigen binding. Proc Natl Acad Sci U S A (1982) 1.39
Structural requirements for the binding of derivatives of D-galactose to two homogeneous murine immunoglobulins. Biochemistry (1974) 1.38
Crystals of phosphorylcholine-binding Fab-fragments from mouse myeloma proteins: preparation and x-ray analysis. Proc Natl Acad Sci U S A (1972) 1.34
Structure and expression of two porcine genomic clones encoding class I MHC antigens. J Immunol (1985) 1.32
Variable region sequence of the heavy chain from a phosphorylcholine binding myeloma protein. Biochemistry (1974) 1.31
OARSI-OMERACT definition of relevant radiological progression in hip/knee osteoarthritis. Osteoarthritis Cartilage (2009) 1.30
Galactan-binding antibodies. Diversity and structure of idiotypes. J Exp Med (1983) 1.30
Size differences among immunoglobulin heavy chains from phosphorylcholine-binding proteins. Proc Natl Acad Sci U S A (1976) 1.27
Polymorphism in immunoglobulin heavy chains suggesting gene conversion. Proc Natl Acad Sci U S A (1982) 1.24
Purification and properties of Gal repressor:pL-galR fusion in pKC31 plasmid vector. J Biol Chem (1987) 1.23
Six BALB-c IgA myeloma proteins that bind beta-(1-6)-D-galactan. Partial amino acid sequences and idiotypes. J Exp Med (1973) 1.22
Monoclonal autoantibodies: an approach to studying autoimmune disease. Mol Immunol (1982) 1.22
Incidence of lung cancer in systemic sclerosis. J Rheumatol (1985) 1.22
The reaction of SLE antibodies with native, single stranded RNA: radioassay and binding specificities. J Immunol (1978) 1.22
A central anti-DNA idiotype in human and murine systemic lupus erythematosus. Eur J Immunol (1985) 1.21
Polymorphism in anti-phosphocholine antibodies reflecting evolution of immunoglobulin families. J Exp Med (1983) 1.21
Expression of multivalency in the affinity chromatography of antibodies. Appendix: Derivation and evaluation of equations for independent bivalent interacting systems in quantitative affinity chromatography. Biochemistry (1979) 1.21
T cell derived IL-6 is differentially required for antigen-specific antibody secretion by primary and secondary B cells. J Immunol (1989) 1.20
Design and conduct of clinical trials in patients with osteoarthritis of the hand: recommendations from a task force of the Osteoarthritis Research Society International. Osteoarthritis Cartilage (2006) 1.19
Insulin-like growth factor I is a dual effector of multiple myeloma cell growth. Blood (2000) 1.17
k Chain variable regions from three galactan binding myeloma proteins. Biochemistry (1978) 1.17
Serum protein signatures detect early radiographic osteoarthritis. Osteoarthritis Cartilage (2008) 1.15
Photodetection in silicon beyond the band edge with surface states. Opt Express (2008) 1.15
A ribonucleic acid-specific antibody produced during autoimmune disease: evidence for nucleotide sequence specificity. Eur J Immunol (1980) 1.15
kappa Chain joining segments and structural diversity of antibody combining sites. Proc Natl Acad Sci U S A (1980) 1.13
A role for interleukin-6 in parathyroid hormone-induced bone resorption in vivo. Endocrinology (1999) 1.13
Anti-DNA antibodies: problems in their study and interpretation. Clin Exp Immunol (1986) 1.13
Immunoglobulin structure--function correlates: antigen binding and idiotypes. Contemp Top Mol Immunol (1983) 1.12
Measurement of structural progression in osteoarthritis of the hip: the Barcelona consensus group. Osteoarthritis Cartilage (2004) 1.12
Characterization of a porcine genomic clone encoding a major histocompatibility antigen: expression in mouse L cells. Proc Natl Acad Sci U S A (1982) 1.12
The experience of pain and emergent osteoarthritis of the knee. Osteoarthritis Cartilage (2001) 1.11
Identification of 50S proteins at the peptidyl-tRNA binding site of Escherichia coli ribosomes. Proc Natl Acad Sci U S A (1973) 1.11
kappa Chain variable region from M167, a phosphorylcholine binding myeloma protein. Biochemistry (1978) 1.07