PubRank

R W Scott

Author PubWeight™ 97.04‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Aggregation and motor neuron toxicity of an ALS-linked SOD1 mutant independent from wild-type SOD1. Science 1998 5.23
2 Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury. Nat Genet 1996 4.77
3 The Involvement of the Aortic Valve in Syphilitic Aortitis. Am J Pathol 1927 3.67
4 Antibiotic proteins of human polymorphonuclear leukocytes. Proc Natl Acad Sci U S A 1989 2.59
5 Tissue-specific activation of a cloned alpha-fetoprotein gene during differentiation of a transfected embryonal carcinoma cell line. Nature 1984 2.02
6 Bactericidal/permeability-increasing protein has endotoxin-neutralizing activity. J Immunol 1990 1.96
7 The role of bactericidal/permeability-increasing protein as a natural inhibitor of bacterial endotoxin. J Immunol 1992 1.92
8 Proviral sequences that restrict retroviral expression in mouse embryonal carcinoma cells. Mol Cell Biol 1987 1.84
9 Reduction of CuZn-superoxide dismutase activity exacerbates neuronal cell injury and edema formation after transient focal cerebral ischemia. J Neurosci 1997 1.84
10 Transient expression of a mouse alpha-fetoprotein minigene: deletion analyses of promoter function. Mol Cell Biol 1983 1.74
11 Intragenic amplification and divergence in the mouse alpha-fetoprotein gene. Nature 1981 1.69
12 alpha-Fetoprotein and albumin genes are in tandem in the mouse genome. Proc Natl Acad Sci U S A 1981 1.67
13 Protease nexin. Properties and a modified purification procedure. J Biol Chem 1985 1.66
14 Purification and characterization of human neutrophil peptide 4, a novel member of the defensin family. J Biol Chem 1989 1.56
15 Cep-1347 (KT7515), a semisynthetic inhibitor of the mixed lineage kinase family. J Biol Chem 2001 1.53
16 Turnover of amyloid beta-protein in mouse brain and acute reduction of its level by phorbol ester. J Neurosci 1998 1.50
17 Presenilin-1 P264L knock-in mutation: differential effects on abeta production, amyloid deposition, and neuronal vulnerability. J Neurosci 2000 1.50
18 Evidence for a stem cell-specific repressor of Moloney murine leukemia virus expression in embryonal carcinoma cells. Mol Cell Biol 1990 1.50
19 Mice lacking cytosolic copper/zinc superoxide dismutase display a distinctive motor axonopathy. Neurology 1999 1.50
20 Targeted deletion of the cytosolic Cu/Zn-superoxide dismutase gene (Sod1) increases susceptibility to noise-induced hearing loss. Audiol Neurootol 1999 1.50
21 Inhibition of tumor-cell-mediated extracellular matrix destruction by a fibroblast proteinase inhibitor, protease nexin I. Proc Natl Acad Sci U S A 1986 1.47
22 Construction and expression in vivo of an internally deleted mouse alpha-fetoprotein gene: presence of a transcribed Alu-like repeat within the first intervening sequence. Nucleic Acids Res 1982 1.40
23 Superoxide-mediated cytotoxicity in superoxide dismutase-deficient fetal fibroblasts. Arch Biochem Biophys 1997 1.40
24 Modulation of secreted beta-amyloid precursor protein and amyloid beta-peptide in brain by cholesterol. J Biol Chem 1998 1.36
25 Enhanced amyloidogenic processing of the beta-amyloid precursor protein in gene-targeted mice bearing the Swedish familial Alzheimer's disease mutations and a "humanized" Abeta sequence. J Biol Chem 1996 1.30
26 Characterization of two azurphil granule proteases with active-site homology to neutrophil elastase. J Biol Chem 1990 1.29
27 Purification of human fibroblast urokinase proenzyme and analysis of its regulation by proteases and protease nexin. J Biol Chem 1984 1.24
28 Negative regulation of retrovirus expression in embryonal carcinoma cells mediated by an intragenic domain. J Virol 1988 1.24
29 Human neutrophil bactericidal/permeability-increasing protein reduces mortality rate from endotoxin challenge: a placebo-controlled study. Crit Care Med 1994 1.23
30 Endotoxin-binding and -neutralizing properties of recombinant bactericidal/permeability-increasing protein and monoclonal antibodies HA-1A and E5. Crit Care Med 1994 1.22
31 CEP-1347/KT-7515, an inhibitor of SAPK/JNK pathway activation, promotes survival and blocks multiple events associated with Abeta-induced cortical neuron apoptosis. J Neurochem 2001 1.21
32 Exacerbation of delayed cell injury after transient global ischemia in mutant mice with CuZn superoxide dismutase deficiency. Stroke 1999 1.21
33 Proteasome inhibition enhances the stability of mouse Cu/Zn superoxide dismutase with mutations linked to familial amyotrophic lateral sclerosis. J Neurol Sci 1996 1.21
34 MPTP activates c-Jun NH(2)-terminal kinase (JNK) and its upstream regulatory kinase MKK4 in nigrostriatal neurons in vivo. J Neurochem 2000 1.14
35 Hindlimb motor neurons require Cu/Zn superoxide dismutase for maintenance of neuromuscular junctions. Am J Pathol 1999 1.13
36 Purification of human protease nexin. J Biol Chem 1983 1.11
37 Cells regulate their mitogenic response to thrombin through release of protease nexin. Nature 1982 1.10
38 Regulation of extracellular plasminogen activator by human fibroblasts. The role of protease nexin. J Biol Chem 1983 1.09
39 Changes in polymorphonuclear leukocyte surface and plasma bactericidal/permeability-increasing protein and plasma lipopolysaccharide binding protein during endotoxemia or sepsis. Arch Surg 1994 1.09
40 Defective hematopoiesis and hepatic steatosis in mice with combined deficiencies of the genes encoding Fancc and Cu/Zn superoxide dismutase. Blood 2001 1.05
41 Enrichment of estradiol-receptor complexes in a transcriptionally active fraction of chromatin from MCF-7 cells. Proc Natl Acad Sci U S A 1980 1.05
42 Relative concentrations of endotoxin-binding proteins in body fluids during infection. Lancet 1994 1.05
43 The ontogeny of a 57-Kd cationic antimicrobial protein of human polymorphonuclear leukocytes: localization to a novel granule population. Blood 1990 1.04
44 BCL-2 overexpression attenuates cortical cell loss after traumatic brain injury in transgenic mice. J Cereb Blood Flow Metab 1998 0.99
45 Bactericidal/permeability-increasing protein and lipopolysaccharide (LPS)-binding protein. LPS binding properties and effects on LPS-mediated cell activation. J Biol Chem 1994 0.97
46 Can strong back extensors prevent vertebral fractures in women with osteoporosis? Mayo Clin Proc 1996 0.95
47 Processing of the beta-amyloid precursor. Multiple proteases generate and degrade potentially amyloidogenic fragments. J Biol Chem 1993 0.93
48 Protection against endotoxic shock by bactericidal/permeability-increasing protein in rats. J Clin Invest 1995 0.91
49 Cloning and characterization of human tissue inhibitor of metalloproteinases-3. DNA Cell Biol 1994 0.90
50 Synthesis of the C29-C44 portion of spongistatin 1 (altohyrtin A). J Org Chem 2000 0.90
51 Biologically active monomeric and heterodimeric recombinant human calpain I produced using the baculovirus expression system. Biochem J 1996 0.88
52 Differential requirements for cellular enhancers in stem and differentiated cells. Nucleic Acids Res 1988 0.87
53 The role of bactericidal/permeability-increasing protein in the treatment of primate bacteremia and septic shock. J Clin Immunol 1994 0.86
54 Edema formation exacerbates neurological and histological outcomes after focal cerebral ischemia in CuZn-superoxide dismutase gene knockout mutant mice. Acta Neurochir Suppl 1997 0.85
55 Activity of antimicrobial peptide mimetics in the oral cavity: I. Activity against biofilms of Candida albicans. Mol Oral Microbiol 2010 0.84
56 Midified roller pump with improved haemodynamic characteristics and temperature control of perfusate. Lab Pract 1976 0.84
57 Activity of antimicrobial peptide mimetics in the oral cavity: II. Activity against periopathogenic biofilms and anti-inflammatory activity. Mol Oral Microbiol 2010 0.83
58 Intracoronary photodynamic therapy reduces neointimal growth without suppressing re-endothelialisation in a porcine model. Heart 2006 0.83
59 Protease specificity and heparin binding and activation of recombinant protease nexin I. J Biol Chem 1991 0.83
60 Quantitative recovery of sugars from silica gel thin layers. J Chromatogr 1970 0.83
61 Ultraviolet spectrophotometric determination of hexoses, pentoses, and uronic acids after their reactions with concentrated sulfuric acid. Anal Biochem 1967 0.83
62 Acanthosis nigricans associated with a benign encephalopathy. Arch Dermatol 1974 0.82
63 A small pulsatile perfusion pump-blood equilibrator system [proceedings]. J Physiol 1978 0.80
64 APP transgenesis: approaches toward the development of animal models for Alzheimer disease neuropathology. Neurobiol Aging 1996 0.79
65 Recombinant human protease nexin-1 prevents articular cartilage-degradation in the rabbit. Agents Actions Suppl 1993 0.79
66 A differentiation between peripheral and central neurokinin receptors using phenoxybenzamine. Eur J Pharmacol 1986 0.78
67 Production and characterization of recombinant mouse brain-derived neurotrophic factor and rat neurotrophin-3 expressed in insect cells. J Neurochem 1994 0.78
68 Effect of knowledge of response on the self-control of heart rate. Psychophysiology 1974 0.77
69 Regulation of the response to bacterial lipopolysaccharide by endogenous and exogenous lipopolysaccharide binding proteins. Blood Purif 1993 0.77
70 From expressed sequence tags to 'epigenomics': an understanding of disease processes. Curr Opin Biotechnol 1997 0.77
71 Proceedings: Improved nerve-muscle apparatus for student experiments. J Physiol 1974 0.76
72 Pilocarpine-induced reciprocal hindlimb scratching in mice. Pharmacol Biochem Behav 1987 0.76
73 A potential new radiopharmaceutical for parathyroid imaging: radiolabeled parathyroid-specific monoclonal antibody--II. Comparison of 125I- and 111In-labeled antibodies. Int J Rad Appl Instrum B 1988 0.75
74 Sequencing the human genome. Science 1993 0.75
75 Altered calcium homeostasis in spinal motoneurons but not in oculomotor neurons of SOD-1 knockout mice. Acta Neuropathol 2000 0.75
76 A potential new radiopharmaceutical for parathyroid imaging: radiolabeled parathyroid-specific monoclonal antibody--I. Evaluation of 125I-labeled antibody in a nude mouse model system. Int J Rad Appl Instrum B 1988 0.75
77 Non-cephalothoracic partial lipodystrophy associated with autoimmune disease. Int J Dermatol 2008 0.75
78 Small animal operating tables with interchangeable fittings. Lab Pract 1970 0.75
79 Differential effects of feedback and reinforcement in voluntary acceleration of human heart rate. Percept Mot Skills 1974 0.75
80 The use of shaping and reinforcement in the operant acceleration and deceleration of heart rate. Behav Res Ther 1973 0.75
81 The recovery of highly purified biopharmaceuticals from perfusion cell culture bioreactors. J Parenter Sci Technol 1989 0.75
82 Strategies to alter the progression of Alzheimer's disease. Curr Opin Biotechnol 1996 0.75
83 On the Employment of Digitalis during the Premonitory Symptoms of Sthenic Epilepsy. Prov Med Surg J 1844 0.75
84 The effects of feedback signal information content of the long-term self-control of heart rate. J Gen Psychol 1974 0.75
85 Cleidocranial dysplasia?an enigma among anomalies. J Orthop Sports Phys Ther 1988 0.75
86 Suppression of headbanging on the ward. Psychol Rep 1975 0.75
87 The A-B scale and empathy, warmth, genuineness, and depth of self-exploration. J Abnorm Psychol 1971 0.75
88 Effects of an Outreach Dental Care Assessment System in a military population. Mil Med 1988 0.75
89 The nursing attendant's role in a rehabilitation setting: conceptions and attitudinal correlates. Nurs Res 1968 0.75
90 Arteriosclerosis. Bull N Y Acad Med 1932 0.75
91 Proceedings: A modified small animal operating table with interchangeable fittings. J Physiol 1974 0.75
92 A shaping procedure for heart-rate control in chronic tachycardia. Percept Mot Skills 1973 0.75
93 Long term instructional control of heart rate without exteroceptive feedback. J Gen Psychol 1975 0.75
94 Case of Bronchorrhœa Æstiva, or Hay-fever: with Remarks. Prov Med J Retrosp Med Sci 1842 0.75