Published in Science on October 26, 1984
3'-Azido-3'-deoxythymidine (BW A509U): an antiviral agent that inhibits the infectivity and cytopathic effect of human T-lymphotropic virus type III/lymphadenopathy-associated virus in vitro. Proc Natl Acad Sci U S A (1985) 10.71
Inhibition of the in vitro infectivity and cytopathic effect of human T-lymphotrophic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV) by 2',3'-dideoxynucleosides. Proc Natl Acad Sci U S A (1986) 6.63
High prevalence of antibodies to acquired immune deficiency syndrome (AIDS)-associated retrovirus (ARV) in AIDS and related conditions but not in other disease states. Proc Natl Acad Sci U S A (1985) 3.35
The natural history of human T lymphotropic virus-III infection: the cause of AIDS. Br Med J (Clin Res Ed) (1986) 1.69
Inhibition of replication and cytopathic effect of human T cell lymphotropic virus type III/lymphadenopathy-associated virus by 3'-azido-3'-deoxythymidine in vitro. Antimicrob Agents Chemother (1986) 1.66
Prevalence of antibody to human T lymphotropic virus type III by risk group and area, United Kingdom 1978-84. Br Med J (Clin Res Ed) (1985) 1.50
Seroepidemiology of HTLV-III antibodies in a remote population of eastern Zaire. Br Med J (Clin Res Ed) (1985) 0.89
Historical review of the causes of cancer. World J Clin Oncol (2016) 0.79
Absence of antibodies to the human immunodeficiency virus in sera from Africa prior to 1975. Proc Natl Acad Sci U S A (1986) 0.78
HIV detection by DNA amplification. J Clin Pathol (1988) 0.75
Origin of AIDS. Br Med J (Clin Res Ed) (1986) 0.75
The 30-year war on AIDS: have we reached the tipping point? Sex Transm Dis (2011) 0.75
Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS). Science (1983) 43.61
T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV. Nature (1985) 21.57
Genome organization and transactivation of the human immunodeficiency virus type 2. Nature (1987) 11.79
Problem-based learning: a review of literature on its outcomes and implementation issues. Acad Med (1993) 10.52
Selective tropism of lymphadenopathy associated virus (LAV) for helper-inducer T lymphocytes. Science (1984) 10.38
Genetic variability of the AIDS virus: nucleotide sequence analysis of two isolates from African patients. Cell (1986) 9.01
Isolation of a new human retrovirus from West African patients with AIDS. Science (1986) 7.97
Antiretroviral drug resistance testing in adult HIV-1 infection: recommendations of an International AIDS Society-USA Panel. JAMA (2000) 7.81
Genomic heterogeneity of AIDS retroviral isolates from North America and Zaire. Science (1985) 6.31
Circulating and intra-articular immune complexes in patients with rheumatoid arthritis. Correlation of 125I-Clq binding activity with clinical and biological features of the disease. J Clin Invest (1976) 5.96
HIV-1 genome nuclear import is mediated by a central DNA flap. Cell (2000) 5.87
Changes in growth properties on passage in tissue culture of viruses derived from infectious molecular clones of HIV-1LAI, HIV-1MAL, and HIV-1ELI. Virology (1991) 5.54
HIV F/3' orf encodes a phosphorylated GTP-binding protein resembling an oncogene product. Nature (1987) 5.45
Cellular proteins bound to immunodeficiency viruses: implications for pathogenesis and vaccines. Science (1992) 5.25
Single amino-acid changes in HIV envelope affect viral tropism and receptor binding. Nature (1989) 5.12
Identification of a new human immunodeficiency virus type 1 distinct from group M and group O. Nat Med (1998) 4.92
HIV-1 reverse transcriptase specifically interacts with the anticodon domain of its cognate primer tRNA. EMBO J (1989) 4.73
Maternal viral load, zidovudine treatment, and the risk of transmission of human immunodeficiency virus type 1 from mother to infant. Pediatric AIDS Clinical Trials Group Protocol 076 Study Group. N Engl J Med (1996) 4.44
Antiretroviral drug resistance testing in adults with HIV infection: implications for clinical management. International AIDS Society--USA Panel. JAMA (1998) 4.42
Cis elements and trans-acting factors involved in the RNA dimerization of the human immunodeficiency virus HIV-1. J Mol Biol (1990) 4.38
Human immunodeficiency viruses. Science (1986) 4.34
Persistent mitochondrial dysfunction and perinatal exposure to antiretroviral nucleoside analogues. Lancet (1999) 4.20
Adaptation of lymphadenopathy associated virus (LAV) to replication in EBV-transformed B lymphoblastoid cell lines. Science (1984) 4.02
A prospective study of infants born to women seropositive for human immunodeficiency virus type 1. HIV Infection in Newborns French Collaborative Study Group. N Engl J Med (1989) 3.98
High-altitude cerebral edema evaluated with magnetic resonance imaging: clinical correlation and pathophysiology. JAMA (1998) 3.81
A comprehensive panel of near-full-length clones and reference sequences for non-subtype B isolates of human immunodeficiency virus type 1. J Virol (1998) 3.65
Problem-based learning: is anatomy a casualty? Surgeon (2005) 3.31
Inactivation of lymphadenopathy-associated virus by heat, gamma rays, and ultraviolet light. Lancet (1985) 3.27
Mosaic genome structure of simian immunodeficiency virus from west African green monkeys. EMBO J (1994) 3.19
Cutting edge: lipoxins rapidly stimulate nonphlogistic phagocytosis of apoptotic neutrophils by monocyte-derived macrophages. J Immunol (2000) 3.07
Human immunodeficiency virus-specific cytotoxic responses of seropositive individuals: distinct types of effector cells mediate killing of targets expressing gag and env proteins. J Virol (1989) 3.05
A possible subunit structure of Rous sarcoma virus RNA. J Gen Virol (1969) 2.96
Simian immunodeficiency virus replicates to high levels in sooty mangabeys without inducing disease. J Virol (1998) 2.94
Molecular cloning and polymorphism of the human immune deficiency virus type 2. Nature (1987) 2.86
Apoptosis in AIDS. Science (1993) 2.86
The specificity of the human immunodeficiency virus type 2 transactivator is different from that of human immunodeficiency virus type 1. EMBO J (1987) 2.85
HIV/HTLV gene nomenclature. Nature (1988) 2.72
Lamivudine-zidovudine combination for prevention of maternal-infant transmission of HIV-1. JAMA (2001) 2.63
Retrospective seroepidemiology of AIDS virus infection in Nairobi populations. J Infect Dis (1987) 2.63
Risk factors for AIDS and HIV seropositivity in homosexual men. Am J Epidemiol (1987) 2.62
Detection of IgG antibodies to lymphadenopathy-associated virus in patients with AIDS or lymphadenopathy syndrome. Lancet (1984) 2.56
Mixed human immunodeficiency virus (HIV) infection in an individual: demonstration of both HIV type 1 and type 2 proviral sequences by using polymerase chain reaction. J Infect Dis (1988) 2.56
A cumulative review of studies on travellers, their experience of illness and the implications of these findings. J Infect (1990) 2.50
Evaluation of clinical case definitions of influenza: detailed investigation of patients during the 1995-1996 epidemic in France. Clin Infect Dis (1999) 2.49
European guidelines on the clinical management of HIV-1 tropism testing. Lancet Infect Dis (2011) 2.47
VPX mutants of HIV-2 are infectious in established cell lines but display a severe defect in peripheral blood lymphocytes. EMBO J (1989) 2.45
The cytopathic effect of HIV is associated with apoptosis. Virology (1991) 2.43
Detection of HIV1 DNA in infants and children by means of the polymerase chain reaction. Lancet (1988) 2.43
Detection of hepatitis C virus in the semen of infected men. Lancet (2000) 2.42
Effects of exercise on fatigue, physical functioning, and emotional distress during radiation therapy for breast cancer. Oncol Nurs Forum (1997) 2.42
The human and simian immunodeficiency viruses HIV-1, HIV-2 and SIV interact with similar epitopes on their cellular receptor, the CD4 molecule. AIDS (1988) 2.35
Isolation of new lymphotropic retrovirus from two siblings with haemophilia B, one with AIDS. Lancet (1984) 2.32
HIV-1-resistance phenotype conferred by combination of two separate inherited mutations of CCR5 gene. Lancet (1998) 2.32
Human immunodeficiency virus type 2 infection associated with AIDS in West Africa. N Engl J Med (1987) 2.32
Longitudinal study of 94 symptomatic infants with perinatally acquired human immunodeficiency virus infection. Evidence for a bimodal expression of clinical and biological symptoms. Am J Dis Child (1990) 2.30
Programmed cell death in AIDS-related HIV and SIV infections. AIDS Res Hum Retroviruses (1993) 2.29
Increase in endocervical CD4 lymphocytes among women with nonulcerative sexually transmitted diseases. J Infect Dis (1998) 2.27
CCR5 chemokine receptor variant in HIV-1 mother-to-child transmission and disease progression in children. French Pediatric HIV Infection Study Group. JAMA (1998) 2.25
HIV-1/HIV-2 seronegativity in HIV-1 subtype O infected patients. Lancet (1994) 2.25
Identification and antigenicity of the major envelope glycoprotein of lymphadenopathy-associated virus. Virology (1985) 2.23
Molecular cloning of lymphadenopathy-associated virus. Nature (1985) 2.22
Diversity of V3 region sequences of human immunodeficiency viruses type 1 from the central African Republic. AIDS Res Hum Retroviruses (1993) 2.22
Programmed cell death and AIDS: significance of T-cell apoptosis in pathogenic and nonpathogenic primate lentiviral infections. Proc Natl Acad Sci U S A (1994) 2.21
Inactivation of lymphadenopathy associated virus by chemical disinfectants. Lancet (1984) 2.19
Several groups among human herpesvirus 6 strains can be distinguished by Southern blotting and polymerase chain reaction. J Clin Microbiol (1991) 2.16
HIV-1 infection in an individual homozygous for CCR5 delta 32. Seroco Study Group. Lancet (1997) 2.11
Microsatellite identification and characterization in peanut ( A. hypogaea L.). Theor Appl Genet (2003) 2.10
Discovery of a Jupiter/Saturn analog with gravitational microlensing. Science (2008) 2.09