J M Stadel

Author PubWeight™ 69.96‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor. J Biol Chem 1980 6.06
2 Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14. Nature 1999 3.20
3 Adenylate cyclase-coupled beta-adrenergic receptors: structure and mechanisms of activation and desensitization. Annu Rev Biochem 1983 2.40
4 Chemokine receptors in human endothelial cells. Functional expression of CXCR4 and its transcriptional regulation by inflammatory cytokines. J Biol Chem 1998 2.02
5 Catecholamine-induced desensitization of turkey erythrocyte adenylate cyclase is associated with phosphorylation of the beta-adrenergic receptor. Proc Natl Acad Sci U S A 1983 1.74
6 Structure and function of alpha-adrenoceptors. Pharmacol Rev 1991 1.50
7 Effects of expression of mammalian G alpha and hybrid mammalian-yeast G alpha proteins on the yeast pheromone response signal transduction pathway. Mol Cell Biol 1990 1.33
8 Ubiquitin fusion augments the yield of cloned gene products in Escherichia coli. Proc Natl Acad Sci U S A 1989 1.30
9 Changes in the structure and function of the human thrombin receptor during receptor activation, internalization, and recycling. J Biol Chem 1994 1.27
10 Desensitization of the beta-adrenergic receptor of frog erythrocytes. Recovery and characterization of the down-regulated receptors in sequestered vesicles. J Biol Chem 1983 1.24
11 Coexpression of human cAMP-specific phosphodiesterase activity and high affinity rolipram binding in yeast. J Biol Chem 1992 1.15
12 Increasing gene expression in yeast by fusion to ubiquitin. J Biol Chem 1989 1.14
13 A high affinity agonist . beta-adrenergic receptor complex is an intermediate for catecholamine stimulation of adenylate cyclase in turkey and frog erythrocyte membranes. J Biol Chem 1980 1.11
14 Molecular mechanisms of coupling in hormone receptor-adenylate cyclase systems. Adv Enzymol Relat Areas Mol Biol 1982 1.08
15 Catecholamine-induced desensitization in turkey erythrocytes: cAMP mediated impairment of high affinity agonist binding without alteration in receptor number. J Cyclic Nucleotide Res 1981 1.07
16 Pharmacologic and therapeutic applications of alpha 2-adrenoceptor subtypes. Annu Rev Pharmacol Toxicol 1993 1.06
17 Loss of beta-adrenergic receptor-guanine nucleotide regulatory protein interactions accompanies decline in catecholamine responsiveness of adenylate cyclase in maturing rat erythrocytes. J Biol Chem 1980 1.03
18 Osteopontin-stimulated vascular smooth muscle cell migration is mediated by beta 3 integrin. Exp Cell Res 1994 1.02
19 Glucocorticoid regulation of beta-adrenergic receptors in 3T3-L1 preadipocytes. Mol Pharmacol 1987 1.02
20 Cloning and characterization of a human angiotensin II type 1 receptor. Biochem Biophys Res Commun 1992 1.01
21 Hormones, receptors, and cyclic AMP: their role in target cell refractoriness. Curr Top Cell Regul 1980 1.00
22 Islet-activating protein inhibits leukotriene D4- and leukotriene C4- but not bradykinin- or calcium ionophore-induced prostacyclin synthesis in bovine endothelial cells. Proc Natl Acad Sci U S A 1986 1.00
23 Orphan G-protein-coupled receptors: the next generation of drug targets? Br J Pharmacol 1998 0.97
24 Catecholamine-induced desensitization of turkey erythrocyte adenylate cyclase. Structural alterations in the beta-adrenergic receptor revealed by photoaffinity labeling. J Biol Chem 1982 0.95
25 Functional integrity of desensitized beta-adrenergic receptors. J Biol Chem 1983 0.94
26 Cell-free desensitization of catecholamine-sensitive adenylate cyclase. Agonist- and cAMP-promoted alterations in turkey erythrocyte beta-adrenergic receptors. J Biol Chem 1984 0.92
27 Functional modification of the guanine nucleotide regulatory protein after desensitization of turkey erythrocytes by catecholamines. Arch Biochem Biophys 1983 0.92
28 Hypothyroidism modulates beta adrenergic receptor adenylate cyclase interactions in rat reticulocytes. J Clin Invest 1981 0.91
29 Osteopontin expression in platelet-derived growth factor-stimulated vascular smooth muscle cells and carotid artery after balloon angioplasty. Arterioscler Thromb Vasc Biol 1996 0.89
30 Tyr-129 is important to the peptide ligand affinity and selectivity of human endothelin type A receptor. Proc Natl Acad Sci U S A 1994 0.87
31 In vitro and in vivo characterization of intrinsic sympathomimetic activity in normal and heart failure rats. J Pharmacol Exp Ther 1999 0.87
32 Regulation of ligand binding to leukotriene D4 receptors: effects of cations and guanine nucleotides. Eur J Pharmacol 1984 0.86
33 Coupling of TGF-beta-induced mitogenesis to G-protein activation in AKR-2B cells. Biochem Biophys Res Commun 1988 0.86
34 Modulation of vitronectin receptor-mediated osteoclast adhesion by Arg-Gly-Asp peptide analogs: a structure-function analysis. J Bone Miner Res 1993 0.86
35 Mechanisms of hormone receptor-effector coupling: the beta-adrenergic receptor and adenylate cyclase. Fed Proc 1982 0.85
36 Calcitonin gene-related peptide receptor independently stimulates 3',5'-cyclic adenosine monophosphate and Ca2+ signaling pathways. Mol Cell Biochem 1999 0.85
37 Multiple reactive sulfhydryl groups modulate the function of adenylate cyclase coupled beta-adrenergic receptors. Mol Pharmacol 1979 0.84
38 Molecular pharmacology of adenylate cyclase-coupled alpha- and beta-adrenergic receptors. Adv Cyclic Nucleotide Res 1981 0.83
39 Evidence that a beta-adrenergic receptor-associated guanine nucleotide regulatory protein conveys guanosine 5'-O-(3-thiotriphosphate)- dependent adenylate cyclase activity. J Biol Chem 1981 0.83
40 Genetic regulation of beta 2-adrenergic receptors in 3T3-L1 fibroblasts. Biochem J 1989 0.83
41 Differential calcitonin gene-related peptide (CGRP) and amylin binding sites in nucleus accumbens and lung: potential models for studying CGRP/amylin receptor subtypes. J Neurochem 1995 0.83
42 Fluoride interaction with G-proteins. Biochem J 1989 0.83
43 Down-regulation of beta-adrenergic receptors by pindolol in Gs alpha-transfected S49 cyc- murine lymphoma cells. J Neurochem 1992 0.82
44 Molecular cloning of a novel chemokine receptor-like gene from early stage chick embryos. Biochem Mol Biol Int 1998 0.81
45 Platelet-activating factor stimulates phosphoinositide turnover in neurohybrid NCB-20 cells: involvement of pertussis toxin-sensitive guanine nucleotide-binding proteins and inhibition by protein kinase C. Mol Pharmacol 1992 0.80
46 Lysine 182 of endothelin B receptor modulates agonist selectivity and antagonist affinity: evidence for the overlap of peptide and non-peptide ligand binding sites. Biochemistry 1994 0.80
47 Differential effects of cholera toxin on guanine nucleotide regulation of beta-adrenergic agonist high affinity binding and adenylate cyclase activation in frog erythrocyte membranes. J Cyclic Nucleotide Res 1981 0.80
48 Alpha-adrenoceptors: recent developments. Med Res Rev 1994 0.80
49 8-P-Chlorophenylthio-cyclic AMP: a potent partial simulator of antidiuretic hormone action. J Cyclic Nucleotide Res 1978 0.79
50 Solubilization of [3H]leukotriene D4 receptor complex from guinea pig lung membranes. Mol Pharmacol 1986 0.79
51 Evidence for multiple, biochemically distinguishable states in the G protein-coupled receptor, rhodopsin. Trends Pharmacol Sci 1998 0.79
52 Phosphorylation of the beta-adrenergic receptor accompanies catecholamine-induced desensitization of turkey erythrocyte adenylate cyclase. Trans Assoc Am Physicians 1983 0.79
53 Structural basis for the selectivity of the RGS protein, GAIP, for Galphai family members. Identification of a single amino acid determinant for selective interaction of Galphai subunits with GAIP. J Biol Chem 1999 0.79
54 Characterization of guinea pig myocardial leukotriene C4 binding sites. Regulation by cations and sulfhydryl-directed reagents. Mol Pharmacol 1985 0.78
55 Biochemical characterization of phosphorylated beta-adrenergic receptors from catecholamine-desensitized turkey erythrocytes. Biochemistry 1986 0.78
56 Molecular structure of the beta-adrenergic receptor. Biochemistry 1985 0.78
57 Subtype-selective regulation of beta adrenergic receptor-adenylyl cyclase coupling by phorbol esters in 3T3-L1 fibroblasts. J Pharmacol Exp Ther 1990 0.78
58 Immunochemical comparison of pertussis toxin substrates in brain and peripheral tissues. Cell Signal 1989 0.77
59 Binding of [3H]-SK&F 107260 and [3H]-SB 214857 to purified integrin alphaIIbbeta3: evidence for a common binding site for cyclic arginyl-glycinyl-aspartic acid peptides and nonpeptides. J Pharmacol Exp Ther 1998 0.77
60 Characterization of [3H]leukotriene D4 binding sites in guinea-pig ventricular myocardium. J Pharmacol Exp Ther 1985 0.77
61 Identification of leukotriene D4 specific binding sites in the membrane preparation isolated from guinea pig lung. Prostaglandins 1984 0.77
62 Molecular mechanisms of beta-adrenergic receptor desensitization. Proc West Pharmacol Soc 1980 0.76
63 Mobilization of extracellular Ca2+ by prostaglandin F2 alpha can be modulated by fluoride in 3T3-L1 fibroblasts. Biochem J 1990 0.76
64 Analogues of the thrombin receptor tethered-ligand enhance mesangial cell proliferation. Cell Signal 1994 0.76
65 Purification and characterization of predominant G-protein from bovine lung membranes. Biochemical and immunochemical comparison with Gi1 and Go purified from brain. Biochem J 1989 0.75
66 Regulation of insulin receptors in frog erythrocytes by insulin and concanavalin A. Evidence for discrete classes of insulin binding sites. Mol Pharmacol 1982 0.75
67 Tumor necrosis factor-mediated biological activities involve a G-protein-dependent mechanism. J Biol Response Mod 1990 0.75
68 Adenylyl cyclase and guanine nucleotide-binding proteins in supersensitive guinea pig ventricles. Mol Pharmacol 1992 0.75
69 Biochemical discrimination of the predominant pertussis toxin substrate of rabbit neutrophils from brain Gi and Go: isoelectric focusing improves resolution of pertussis toxin substrates. Biochem Int 1988 0.75
70 Expression and characterization of the long and short splice variants of GS alpha in S49 cyc- cells. Mol Pharmacol 1991 0.75
71 Photoaffinity labeling of the antidiuretic hormone receptor. J Membr Biol 1978 0.75
72 Molecular cloning of a gene from 'chromosome 3 specific' genomic library that encodes a novel CC-chemokine receptor like isotype. Biochem Mol Biol Int 1996 0.75
73 Synthesis and characterization of 2-nitro-5-aziodobenzoylglycyloxytocin, an oxytocin photoaffinity label. Biochemistry 1978 0.75
74 Photoaffinity labeling of beta-adrenergic receptors. Pharmacol Ther 1985 0.75
75 Structure and function of beta-adrenergic receptors: regulation at the molecular level. Adv Cyclic Nucleotide Protein Phosphorylation Res 1984 0.75
76 Studies on alpha v beta 3/ligand interactions using a [3H]SK&F-107260 binding assay. Mol Pharmacol 1996 0.75
77 Reconstitution of the Gs protein from B16 melanoma clones of high and low experimental metastatic potential into S49 cyc-membranes. Biochem Biophys Res Commun 1987 0.75
78 Mechanisms of adaptive supersensitivity: correlation of guinea pig atrial supersensitivity with modifications in adenylyl cyclase activity. Biochem Pharmacol 1997 0.75