Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor.
|
J Biol Chem
|
1980
|
6.06
|
2
|
Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14.
|
Nature
|
1999
|
3.20
|
3
|
Adenylate cyclase-coupled beta-adrenergic receptors: structure and mechanisms of activation and desensitization.
|
Annu Rev Biochem
|
1983
|
2.40
|
4
|
Chemokine receptors in human endothelial cells. Functional expression of CXCR4 and its transcriptional regulation by inflammatory cytokines.
|
J Biol Chem
|
1998
|
2.02
|
5
|
Catecholamine-induced desensitization of turkey erythrocyte adenylate cyclase is associated with phosphorylation of the beta-adrenergic receptor.
|
Proc Natl Acad Sci U S A
|
1983
|
1.74
|
6
|
Structure and function of alpha-adrenoceptors.
|
Pharmacol Rev
|
1991
|
1.50
|
7
|
Effects of expression of mammalian G alpha and hybrid mammalian-yeast G alpha proteins on the yeast pheromone response signal transduction pathway.
|
Mol Cell Biol
|
1990
|
1.33
|
8
|
Ubiquitin fusion augments the yield of cloned gene products in Escherichia coli.
|
Proc Natl Acad Sci U S A
|
1989
|
1.30
|
9
|
Changes in the structure and function of the human thrombin receptor during receptor activation, internalization, and recycling.
|
J Biol Chem
|
1994
|
1.27
|
10
|
Desensitization of the beta-adrenergic receptor of frog erythrocytes. Recovery and characterization of the down-regulated receptors in sequestered vesicles.
|
J Biol Chem
|
1983
|
1.24
|
11
|
Coexpression of human cAMP-specific phosphodiesterase activity and high affinity rolipram binding in yeast.
|
J Biol Chem
|
1992
|
1.15
|
12
|
Increasing gene expression in yeast by fusion to ubiquitin.
|
J Biol Chem
|
1989
|
1.14
|
13
|
A high affinity agonist . beta-adrenergic receptor complex is an intermediate for catecholamine stimulation of adenylate cyclase in turkey and frog erythrocyte membranes.
|
J Biol Chem
|
1980
|
1.11
|
14
|
Molecular mechanisms of coupling in hormone receptor-adenylate cyclase systems.
|
Adv Enzymol Relat Areas Mol Biol
|
1982
|
1.08
|
15
|
Catecholamine-induced desensitization in turkey erythrocytes: cAMP mediated impairment of high affinity agonist binding without alteration in receptor number.
|
J Cyclic Nucleotide Res
|
1981
|
1.07
|
16
|
Pharmacologic and therapeutic applications of alpha 2-adrenoceptor subtypes.
|
Annu Rev Pharmacol Toxicol
|
1993
|
1.06
|
17
|
Loss of beta-adrenergic receptor-guanine nucleotide regulatory protein interactions accompanies decline in catecholamine responsiveness of adenylate cyclase in maturing rat erythrocytes.
|
J Biol Chem
|
1980
|
1.03
|
18
|
Osteopontin-stimulated vascular smooth muscle cell migration is mediated by beta 3 integrin.
|
Exp Cell Res
|
1994
|
1.02
|
19
|
Glucocorticoid regulation of beta-adrenergic receptors in 3T3-L1 preadipocytes.
|
Mol Pharmacol
|
1987
|
1.02
|
20
|
Cloning and characterization of a human angiotensin II type 1 receptor.
|
Biochem Biophys Res Commun
|
1992
|
1.01
|
21
|
Hormones, receptors, and cyclic AMP: their role in target cell refractoriness.
|
Curr Top Cell Regul
|
1980
|
1.00
|
22
|
Islet-activating protein inhibits leukotriene D4- and leukotriene C4- but not bradykinin- or calcium ionophore-induced prostacyclin synthesis in bovine endothelial cells.
|
Proc Natl Acad Sci U S A
|
1986
|
1.00
|
23
|
Orphan G-protein-coupled receptors: the next generation of drug targets?
|
Br J Pharmacol
|
1998
|
0.97
|
24
|
Catecholamine-induced desensitization of turkey erythrocyte adenylate cyclase. Structural alterations in the beta-adrenergic receptor revealed by photoaffinity labeling.
|
J Biol Chem
|
1982
|
0.95
|
25
|
Functional integrity of desensitized beta-adrenergic receptors.
|
J Biol Chem
|
1983
|
0.94
|
26
|
Cell-free desensitization of catecholamine-sensitive adenylate cyclase. Agonist- and cAMP-promoted alterations in turkey erythrocyte beta-adrenergic receptors.
|
J Biol Chem
|
1984
|
0.92
|
27
|
Functional modification of the guanine nucleotide regulatory protein after desensitization of turkey erythrocytes by catecholamines.
|
Arch Biochem Biophys
|
1983
|
0.92
|
28
|
Hypothyroidism modulates beta adrenergic receptor adenylate cyclase interactions in rat reticulocytes.
|
J Clin Invest
|
1981
|
0.91
|
29
|
Osteopontin expression in platelet-derived growth factor-stimulated vascular smooth muscle cells and carotid artery after balloon angioplasty.
|
Arterioscler Thromb Vasc Biol
|
1996
|
0.89
|
30
|
Tyr-129 is important to the peptide ligand affinity and selectivity of human endothelin type A receptor.
|
Proc Natl Acad Sci U S A
|
1994
|
0.87
|
31
|
In vitro and in vivo characterization of intrinsic sympathomimetic activity in normal and heart failure rats.
|
J Pharmacol Exp Ther
|
1999
|
0.87
|
32
|
Regulation of ligand binding to leukotriene D4 receptors: effects of cations and guanine nucleotides.
|
Eur J Pharmacol
|
1984
|
0.86
|
33
|
Coupling of TGF-beta-induced mitogenesis to G-protein activation in AKR-2B cells.
|
Biochem Biophys Res Commun
|
1988
|
0.86
|
34
|
Modulation of vitronectin receptor-mediated osteoclast adhesion by Arg-Gly-Asp peptide analogs: a structure-function analysis.
|
J Bone Miner Res
|
1993
|
0.86
|
35
|
Mechanisms of hormone receptor-effector coupling: the beta-adrenergic receptor and adenylate cyclase.
|
Fed Proc
|
1982
|
0.85
|
36
|
Calcitonin gene-related peptide receptor independently stimulates 3',5'-cyclic adenosine monophosphate and Ca2+ signaling pathways.
|
Mol Cell Biochem
|
1999
|
0.85
|
37
|
Multiple reactive sulfhydryl groups modulate the function of adenylate cyclase coupled beta-adrenergic receptors.
|
Mol Pharmacol
|
1979
|
0.84
|
38
|
Molecular pharmacology of adenylate cyclase-coupled alpha- and beta-adrenergic receptors.
|
Adv Cyclic Nucleotide Res
|
1981
|
0.83
|
39
|
Evidence that a beta-adrenergic receptor-associated guanine nucleotide regulatory protein conveys guanosine 5'-O-(3-thiotriphosphate)- dependent adenylate cyclase activity.
|
J Biol Chem
|
1981
|
0.83
|
40
|
Genetic regulation of beta 2-adrenergic receptors in 3T3-L1 fibroblasts.
|
Biochem J
|
1989
|
0.83
|
41
|
Differential calcitonin gene-related peptide (CGRP) and amylin binding sites in nucleus accumbens and lung: potential models for studying CGRP/amylin receptor subtypes.
|
J Neurochem
|
1995
|
0.83
|
42
|
Fluoride interaction with G-proteins.
|
Biochem J
|
1989
|
0.83
|
43
|
Down-regulation of beta-adrenergic receptors by pindolol in Gs alpha-transfected S49 cyc- murine lymphoma cells.
|
J Neurochem
|
1992
|
0.82
|
44
|
Molecular cloning of a novel chemokine receptor-like gene from early stage chick embryos.
|
Biochem Mol Biol Int
|
1998
|
0.81
|
45
|
Platelet-activating factor stimulates phosphoinositide turnover in neurohybrid NCB-20 cells: involvement of pertussis toxin-sensitive guanine nucleotide-binding proteins and inhibition by protein kinase C.
|
Mol Pharmacol
|
1992
|
0.80
|
46
|
Lysine 182 of endothelin B receptor modulates agonist selectivity and antagonist affinity: evidence for the overlap of peptide and non-peptide ligand binding sites.
|
Biochemistry
|
1994
|
0.80
|
47
|
Differential effects of cholera toxin on guanine nucleotide regulation of beta-adrenergic agonist high affinity binding and adenylate cyclase activation in frog erythrocyte membranes.
|
J Cyclic Nucleotide Res
|
1981
|
0.80
|
48
|
Alpha-adrenoceptors: recent developments.
|
Med Res Rev
|
1994
|
0.80
|
49
|
8-P-Chlorophenylthio-cyclic AMP: a potent partial simulator of antidiuretic hormone action.
|
J Cyclic Nucleotide Res
|
1978
|
0.79
|
50
|
Solubilization of [3H]leukotriene D4 receptor complex from guinea pig lung membranes.
|
Mol Pharmacol
|
1986
|
0.79
|
51
|
Evidence for multiple, biochemically distinguishable states in the G protein-coupled receptor, rhodopsin.
|
Trends Pharmacol Sci
|
1998
|
0.79
|
52
|
Phosphorylation of the beta-adrenergic receptor accompanies catecholamine-induced desensitization of turkey erythrocyte adenylate cyclase.
|
Trans Assoc Am Physicians
|
1983
|
0.79
|
53
|
Structural basis for the selectivity of the RGS protein, GAIP, for Galphai family members. Identification of a single amino acid determinant for selective interaction of Galphai subunits with GAIP.
|
J Biol Chem
|
1999
|
0.79
|
54
|
Characterization of guinea pig myocardial leukotriene C4 binding sites. Regulation by cations and sulfhydryl-directed reagents.
|
Mol Pharmacol
|
1985
|
0.78
|
55
|
Biochemical characterization of phosphorylated beta-adrenergic receptors from catecholamine-desensitized turkey erythrocytes.
|
Biochemistry
|
1986
|
0.78
|
56
|
Molecular structure of the beta-adrenergic receptor.
|
Biochemistry
|
1985
|
0.78
|
57
|
Subtype-selective regulation of beta adrenergic receptor-adenylyl cyclase coupling by phorbol esters in 3T3-L1 fibroblasts.
|
J Pharmacol Exp Ther
|
1990
|
0.78
|
58
|
Immunochemical comparison of pertussis toxin substrates in brain and peripheral tissues.
|
Cell Signal
|
1989
|
0.77
|
59
|
Binding of [3H]-SK&F 107260 and [3H]-SB 214857 to purified integrin alphaIIbbeta3: evidence for a common binding site for cyclic arginyl-glycinyl-aspartic acid peptides and nonpeptides.
|
J Pharmacol Exp Ther
|
1998
|
0.77
|
60
|
Characterization of [3H]leukotriene D4 binding sites in guinea-pig ventricular myocardium.
|
J Pharmacol Exp Ther
|
1985
|
0.77
|
61
|
Identification of leukotriene D4 specific binding sites in the membrane preparation isolated from guinea pig lung.
|
Prostaglandins
|
1984
|
0.77
|
62
|
Molecular mechanisms of beta-adrenergic receptor desensitization.
|
Proc West Pharmacol Soc
|
1980
|
0.76
|
63
|
Mobilization of extracellular Ca2+ by prostaglandin F2 alpha can be modulated by fluoride in 3T3-L1 fibroblasts.
|
Biochem J
|
1990
|
0.76
|
64
|
Analogues of the thrombin receptor tethered-ligand enhance mesangial cell proliferation.
|
Cell Signal
|
1994
|
0.76
|
65
|
Purification and characterization of predominant G-protein from bovine lung membranes. Biochemical and immunochemical comparison with Gi1 and Go purified from brain.
|
Biochem J
|
1989
|
0.75
|
66
|
Regulation of insulin receptors in frog erythrocytes by insulin and concanavalin A. Evidence for discrete classes of insulin binding sites.
|
Mol Pharmacol
|
1982
|
0.75
|
67
|
Tumor necrosis factor-mediated biological activities involve a G-protein-dependent mechanism.
|
J Biol Response Mod
|
1990
|
0.75
|
68
|
Adenylyl cyclase and guanine nucleotide-binding proteins in supersensitive guinea pig ventricles.
|
Mol Pharmacol
|
1992
|
0.75
|
69
|
Biochemical discrimination of the predominant pertussis toxin substrate of rabbit neutrophils from brain Gi and Go: isoelectric focusing improves resolution of pertussis toxin substrates.
|
Biochem Int
|
1988
|
0.75
|
70
|
Expression and characterization of the long and short splice variants of GS alpha in S49 cyc- cells.
|
Mol Pharmacol
|
1991
|
0.75
|
71
|
Photoaffinity labeling of the antidiuretic hormone receptor.
|
J Membr Biol
|
1978
|
0.75
|
72
|
Molecular cloning of a gene from 'chromosome 3 specific' genomic library that encodes a novel CC-chemokine receptor like isotype.
|
Biochem Mol Biol Int
|
1996
|
0.75
|
73
|
Synthesis and characterization of 2-nitro-5-aziodobenzoylglycyloxytocin, an oxytocin photoaffinity label.
|
Biochemistry
|
1978
|
0.75
|
74
|
Photoaffinity labeling of beta-adrenergic receptors.
|
Pharmacol Ther
|
1985
|
0.75
|
75
|
Structure and function of beta-adrenergic receptors: regulation at the molecular level.
|
Adv Cyclic Nucleotide Protein Phosphorylation Res
|
1984
|
0.75
|
76
|
Studies on alpha v beta 3/ligand interactions using a [3H]SK&F-107260 binding assay.
|
Mol Pharmacol
|
1996
|
0.75
|
77
|
Reconstitution of the Gs protein from B16 melanoma clones of high and low experimental metastatic potential into S49 cyc-membranes.
|
Biochem Biophys Res Commun
|
1987
|
0.75
|
78
|
Mechanisms of adaptive supersensitivity: correlation of guinea pig atrial supersensitivity with modifications in adenylyl cyclase activity.
|
Biochem Pharmacol
|
1997
|
0.75
|