Published in Biochem Pharmacol on June 15, 1980
5'-Nucleotidase: molecular structure and functional aspects. Biochem J (1992) 3.08
Neuronal adenosine release, and not astrocytic ATP release, mediates feedback inhibition of excitatory activity. Proc Natl Acad Sci U S A (2012) 1.74
Calcium-dependent currents in cultured rat dorsal root ganglion neurones are inhibited by an adenosine analogue. J Physiol (1986) 1.58
Stimulation of high-affinity adenosine A2 receptors decreases the affinity of dopamine D2 receptors in rat striatal membranes. Proc Natl Acad Sci U S A (1991) 1.39
Adenosine agonists reduce voltage-dependent calcium conductance of mouse sensory neurones in cell culture. J Physiol (1986) 1.35
Adenosine dysfunction in epilepsy. Glia (2011) 1.14
Physiological roles of A1 and A2A adenosine receptors in regulating heart rate, body temperature, and locomotion as revealed using knockout mice and caffeine. Am J Physiol Heart Circ Physiol (2009) 1.08
Effects of extracellular ATP on ion transport systems and [Ca2+]i in rat parotid acinar cells. Comparison with the muscarinic agonist carbachol. J Gen Physiol (1990) 1.08
2-Chloroadenosine reduces the N calcium current of cultured mouse sensory neurones in a pertussis toxin-sensitive manner. J Physiol (1989) 1.06
The presynaptic regulation of noradrenaline release differs in mesenteric arteries of the rabbit and guinea-pig. J Physiol (1984) 1.04
Purine receptors in the guinea-pig internal anal sphincter. Br J Pharmacol (1983) 1.01
Caffeine protects against disruptions of the blood-brain barrier in animal models of Alzheimer's and Parkinson's diseases. J Alzheimers Dis (2010) 1.01
Purine receptors in the rat anococcygeus muscle. J Physiol (1983) 1.00
Prejunctional modulation of noradrenaline release in mouse and rat vas deferens: contribution of P1- and P2-purinoceptors. Br J Pharmacol (1993) 0.98
Interactions between the effects of adenosine and calcium on synaptic responses in rat hippocampus in vitro. J Physiol (1984) 0.97
Adenosine kinase deficiency: expanding the clinical spectrum and evaluating therapeutic options. J Inherit Metab Dis (2015) 0.90
Does ATP cross the cell plasma membrane. Yale J Biol Med (1982) 0.90
Thyroid status and adenosine content of adipose tissue. Biochem J (1987) 0.90
Uptake of adenosine and release of adenine derivatives in mammalian non-myelinated nerve fibres at rest and during activity. J Physiol (1982) 0.89
Endogenous adenosine and adenosine receptors localized to ganglion cells of the retina. Proc Natl Acad Sci U S A (1987) 0.89
Adenosine-modulation of cholinergic and non-adrenergic non-cholinergic neurotransmission in the rabbit iris sphincter. Br J Pharmacol (1986) 0.86
Characterization of the adenosine receptors mediating hypothermia in the conscious mouse. Br J Pharmacol (1994) 0.85
Modulatory effect of adenosine receptors on the ascending and descending neural reflex responses of rat ileum. BMC Neurosci (2002) 0.85
Facilitation by clonidine of purine release induced by high KCl from the rabbit pulmonary artery. Br J Pharmacol (1981) 0.85
Caffeine enhances the slow-pressor response to angiotensin II in rats. Evidence for a caffeine-angiotensin II interaction with the sympathetic nervous system. J Clin Invest (1987) 0.85
Adenosine strongly potentiates pressor responses to nicotine in rats. Proc Natl Acad Sci U S A (1984) 0.85
Interaction of dihydropyridine calcium channel agonists and antagonists with adenosine receptors. Pharmacol Toxicol (1987) 0.84
Rethinking the purinergic neuron-glia connection. Proc Natl Acad Sci U S A (2012) 0.84
Chronic caffeine administration exacerbates renovascular, but not genetic, hypertension in rats. J Clin Invest (1986) 0.83
Endogenous adenosine and hemorrhagic shock: effects of caffeine administration or caffeine withdrawal. Proc Natl Acad Sci U S A (1988) 0.83
ATP modulates the efferent function of capsaicin-sensitive neurones in guinea-pig isolated atria. Br J Pharmacol (1992) 0.82
A study of the actions of P1-purinoceptor agonists and antagonists in the mouse vas deferens in vitro. Br J Pharmacol (1988) 0.82
The potential of caffeine for functional modification from cortical synapses to neuron networks in the brain. Curr Neuropharmacol (2005) 0.82
Release of adenosine, inosine and hypoxanthine from rabbit non-myelinated nerve fibres at rest and during activity. J Physiol (1984) 0.81
Absence of P2-purinoceptors in hippocampal pathways. Br J Pharmacol (1989) 0.81
Biphasic effect of methylxanthines on acetylcholine release from electrically-stimulated brain slices. Br J Pharmacol (1984) 0.80
Release inhibitory receptors activation favours the A2A-adenosine receptor-mediated facilitation of noradrenaline release in isolated rat tail artery. Br J Pharmacol (2002) 0.80
Changes in the activities of adenosine-metabolizing enzymes in six regions of the rat brain on chemical induction of hypothyroidism. Biochem J (1989) 0.79
Presynaptic P1-purinoceptors in jejunal branches of the rabbit mesenteric artery and their possible function. J Physiol (1988) 0.79
Suppression of reperfusion arrhythmia by ischemic preconditioning in the rat: is it mediated by the adenosine receptor, prostaglandin, or bradykinin receptor? Basic Res Cardiol (1995) 0.79
Comparison of the binding properties of A1 adenosine receptors in brain membranes of two congeneric marine fishes living at different depths. J Comp Physiol B (1987) 0.78
5'-Nucleotidase activity in human astrocytomas. Acta Neuropathol (1983) 0.76
Participation of prostaglandin E2 in the purinergic neurotransmission of gut. Gut (1987) 0.75
Ocular Applications of Dipyridamole: A Review of Indications and Routes of Administration. J Ocul Pharmacol Ther (2015) 0.75
Leukotrienes are potent constrictors of human bronchi. Nature (1980) 4.04
Leukotrienes promote plasma leakage and leukocyte adhesion in postcapillary venules: in vivo effects with relevance to the acute inflammatory response. Proc Natl Acad Sci U S A (1981) 3.42
Hyperalgesia, anxiety, and decreased hypoxic neuroprotection in mice lacking the adenosine A1 receptor. Proc Natl Acad Sci U S A (2001) 2.73
Bronchial hyperreactivity to prostaglandin F 2 and histamine in patients with asthma. Br Med J (1973) 2.65
Heparin-binding protein (HBP/CAP37): a missing link in neutrophil-evoked alteration of vascular permeability. Nat Med (2001) 2.45
Comparative pharmacology of human adenosine receptor subtypes - characterization of stably transfected receptors in CHO cells. Naunyn Schmiedebergs Arch Pharmacol (1998) 2.43
Adenosine-dopamine receptor-receptor interactions as an integrative mechanism in the basal ganglia. Trends Neurosci (1997) 2.23
How does adenosine inhibit transmitter release? Trends Pharmacol Sci (1988) 2.20
A modification of a protein-binding method for rapid quantification of cAMP in cell-culture supernatants and body fluid. Anal Biochem (1990) 2.11
Effects of adenosine on adrenergic neurotransmission; prejunctional inhibition and postjunctional enhancement. Naunyn Schmiedebergs Arch Pharmacol (1976) 2.09
The birth and postnatal development of purinergic signalling. Acta Physiol (Oxf) (2010) 2.06
Identification and biological activity of novel omega-oxidized metabolites of leukotriene B4 from human leukocytes. FEBS Lett (1981) 2.04
Allergen challenge of lung tissue from asthmatics elicits bronchial contraction that correlates with the release of leukotrienes C4, D4, and E4. Proc Natl Acad Sci U S A (1983) 2.01
Increased plasma levels of 15-keto-13,14-dihydro-prostaglandin F2X after allergen-provoked asthma in man. Lancet (1974) 2.00
Inhibitory action of prostaglandins E1 and E2 on the neuromuscular transmission in the guinea pig vas deferens. Acta Physiol Scand (1969) 1.95
Basic mechanisms of prostaglandin action on autonomic neurotransmission. Annu Rev Pharmacol Toxicol (1977) 1.91
Prostaglandin endoperoxides IV. Effects on smooth muscle. Life Sci (1975) 1.89
Comparison of the effects of prostaglandins E 1, E 2 and F 2 alpha on the sympathetically stimulated rabbit heart. Acta Physiol Scand (1971) 1.77
Distribution, biochemistry and function of striatal adenosine A2A receptors. Prog Neurobiol (1999) 1.76
Diabetes-induced hyperfiltration in adenosine A(1)-receptor deficient mice lacking the tubuloglomerular feedback mechanism. Acta Physiol (Oxf) (2007) 1.71
Effect of prostaglandins F2 alpha and E2 on airway conductance in healthy subjects and asthmatic patients. Am Rev Respir Dis (1975) 1.66
Xanthine derivatives as adenosine receptor antagonists. Eur J Pharmacol (1982) 1.62
On the mechanism of relaxation of tracheal muscle by theophylline and other cyclic nucleotide phosphodiesterase inhibitors. Acta Pharmacol Toxicol (Copenh) (1979) 1.58
Evidence for an alpha- and beta2-receptor mediated inhibition of the twitch response in the guinea pig vas deferens by noradrenaline. Acta Physiol Scand (1975) 1.53
beta1 integrins are critically involved in neutrophil locomotion in extravascular tissue In vivo. J Exp Med (1998) 1.49
Control by prostaglandin E2 of sympathetic neurotrans-mission in the spleen. Life Sci (1970) 1.47
Adenosine increases LPS-induced nuclear factor kappa B activation in smooth muscle cells via an intracellular mechanism and modulates it via actions on adenosine receptors. Acta Physiol (Oxf) (2013) 1.42
Increase in vascular permeability induced by leukotriene B4 and the role of polymorphonuclear leukocytes. Inflammation (1982) 1.41
Inhibition of sodium-linked glucose reabsorption normalizes diabetes-induced glomerular hyperfiltration in conscious adenosine A₁-receptor deficient mice. Acta Physiol (Oxf) (2013) 1.40
Adenosine and brain ischemia. Cerebrovasc Brain Metab Rev (1992) 1.40
Adenosine-dopamine interactions in the brain. Neuroscience (1992) 1.39
The release of adenosine and inosine from canine subcutaneous adipose tissue by nerve stimulation and noradrenaline. J Physiol (1981) 1.39
Adenosine signaling and function in glial cells. Cell Death Differ (2009) 1.39
Stimulation of high-affinity adenosine A2 receptors decreases the affinity of dopamine D2 receptors in rat striatal membranes. Proc Natl Acad Sci U S A (1991) 1.39
Neuroprotective role of adenosine in cerebral ischaemia. Trends Pharmacol Sci (1992) 1.38
Adenosine receptors. Med Biol (1982) 1.37
Comparison of CGS 15943, ZM 241385 and SCH 58261 as antagonists at human adenosine receptors. Naunyn Schmiedebergs Arch Pharmacol (1999) 1.35
Purine levels in the intact rat brain. Studies with an implanted perfused hollow fibre. Neurosci Lett (1982) 1.34
Inhibition by prostaglandin E2 of sympathetic neurotransmission in the rabbit heart. Acta Physiol Scand (1970) 1.32
Leukotriene C4 affects pulmonary and cardiovascular dynamics in monkey. Nature (1982) 1.31
Regulation of the phosphorylation of the dopamine- and cAMP-regulated phosphoprotein of 32 kDa in vivo by dopamine D1, dopamine D2, and adenosine A2A receptors. Proc Natl Acad Sci U S A (2000) 1.30
Activation of adenosine A2A and dopamine D1 receptors stimulates cyclic AMP-dependent phosphorylation of DARPP-32 in distinct populations of striatal projection neurons. Neuroscience (1998) 1.29
Perivascular peptides relax cerebral arteries concomitant with stimulation of cyclic adenosine monophosphate accumulation or release of an endothelium-derived relaxing factor in the cat. Neurosci Lett (1985) 1.29
Human adenosine A(1), A(2A), A(2B), and A(3) receptors expressed in Chinese hamster ovary cells all mediate the phosphorylation of extracellular-regulated kinase 1/2. Mol Pharmacol (2000) 1.29
Chemoattractant-induced firm adhesion of leukocytes to vascular endothelium in vivo is critically dependent on initial leukocyte rolling. Acta Physiol Scand (1992) 1.29
Neuropeptide Y receptor in pig spleen: binding characteristics, reduction of cyclic AMP formation and calcium antagonist inhibition of vasoconstriction. Eur J Pharmacol (1988) 1.28
Adenosine A(2A) receptors are colocalized with and activate g(olf) in rat striatum. Mol Pharmacol (2000) 1.27
Extracellular levels of adenosine and its metabolites in the striatum of awake rats: inhibition of uptake and metabolism. Acta Physiol Scand (1991) 1.27
Effect of theophylline and other drugs on rabbit renal cyclic nucleotide phosphodiesterase, 5'-nucleotidase and adenosine deaminase. Biochem Pharmacol (1978) 1.27
Endogenous nitric oxide as a probable modulator of pulmonary circulation and hypoxic pressor response in vivo. Acta Physiol Scand (1990) 1.26
Adenosine receptor ligands: differences with acute versus chronic treatment. Trends Pharmacol Sci (1996) 1.25
Isomerization of prostaglandin H2 into prostaglandin D2 in the presence of serum albumin. Biochim Biophys Acta (1976) 1.25
Biological profile of leukotrienes C4 and D4. Acta Physiol Scand (1980) 1.25
Involvement of endoperoxides and thromboxanes in anaphylactic reactions. Adv Prostaglandin Thromboxane Res (1976) 1.24
Pharmacology of adenosine A2A receptors. Trends Pharmacol Sci (1996) 1.23
Inhibitory effect of adenosine on adrenergic neuroeffector transmission in the rabbit heart. Acta Physiol Scand (1979) 1.23
ATP and its metabolite adenosine act synergistically to mobilize intracellular calcium via the formation of inositol 1,4,5-trisphosphate in a smooth muscle cell line. J Biol Chem (1992) 1.23
Signaling via beta(2) integrins triggers neutrophil-dependent alteration in endothelial barrier function. J Exp Med (2000) 1.23
The relative role of recapture and of de novo synthesis for the maintenance of neurotransmitter homeostasis in noradrenergic nerves. Acta Physiol Scand (1969) 1.22
Intracellular formation and release of adenosine from rat hippocampal slices evoked by electrical stimulation or energy depletion. Neurochem Int (1993) 1.21
Adenosine analogues depress ventilation in rabbit neonates. Theophylline stimulation of respiration via adenosine receptors? Pediatr Res (1984) 1.21
Studies on the effect of prostaglandins E1 and E2 on the sympathetic neuromuscular transmission in some animal tissues. Acta Physiol Scand Suppl (1970) 1.21
Adenosine A1 receptors inhibit adenylate cyclase activity and neurotransmitter release and hyperpolarize pyramidal neurons in rat hippocampus. J Pharmacol Exp Ther (1989) 1.20
Antagonistic effects of theophylline and adenosine on adrenergic neuroeffector transmission in the rabbit kidney. Circ Res (1978) 1.19
Adenosine receptors mediating cyclic AMP production in the rat hippocampus. J Neurochem (1982) 1.19
Caffeine--an atypical drug of dependence. Drug Alcohol Depend (1998) 1.19
On the mechanism of action of theophylline and caffeine. Acta Med Scand (1985) 1.18
Evidence for functionally important adenosine A2a receptors in the rat hippocampus. Brain Res (1994) 1.17
Prostaglandin-induced neurotransmission failure in the field-stimulated, isolated vas deferens. Neuropharmacology (1972) 1.17
A novel 8-phenyl-substituted xanthine derivative is a selective antagonist at adenosine A1-receptors in vivo. Acta Physiol Scand (1985) 1.16
Identification of 15-hydroxy-5,8,11,13-eicosatetraenoic acid (15-HETE) as a major metabolite of arachidonic acid in human lung. Acta Physiol Scand (1980) 1.16
Neuropeptide Y is a potent inhibitor of cyclic AMP accumulation in feline cerebral blood vessels. Acta Physiol Scand (1985) 1.15
Integrin alpha(2)beta(1) (VLA-2) is a principal receptor used by neutrophils for locomotion in extravascular tissue. Blood (2000) 1.15
Cellular expression of adenosine A2A receptor messenger RNA in the rat central nervous system with special reference to dopamine innervated areas. Neuroscience (1997) 1.14
Prostaglandin action on transmitter release of adrenergic neuroeffector junctions. Adv Prostaglandin Thromboxane Res (1976) 1.14
Leukotrienes C4, D4 and E4 cause widespread and extensive plasma extravasation in the guinea pig. Naunyn Schmiedebergs Arch Pharmacol (1985) 1.14
Localization of adenosine receptor messenger RNAs in the rat eye. Exp Eye Res (1997) 1.13
Enhancement of acute allergic inflammation by indomethacin is reversed by prostaglandin E2: apparent correlation with in vivo modulation of mediator release. Proc Natl Acad Sci U S A (1988) 1.13
Neurotransmitter quantum released from sympathetic nerves in cat's skeletal muscle. Life Sci (1969) 1.12
Contractile activities of several cysteine-containing leukotrienes in the guinea-pig lung strip. Eur J Pharmacol (1982) 1.11
Inhibition by prostaglandin E1 of noradrenaline release and of effector response to nerve stimulation in the cat spleen. Life Sci (1969) 1.11
Actions of prostacyclin (PGI2) on adrenergic neuroeffector transmission in the rabbit kidney. Prostaglandins (1979) 1.09
Release of prostaglandins and histamine from sensitized and anaphylactic guinea pig lungs--changes in cyclic AMP levels. Biochem Pharmacol (1977) 1.09
Distribution of adenosine receptors in the postmortem human brain: an extended autoradiographic study. Synapse (1997) 1.09
Adenosine A(2A) receptor facilitation of hippocampal synaptic transmission is dependent on tonic A(1) receptor inhibition. Neuroscience (2002) 1.09
Adenosine receptors mediating inhibitory electrophysiological responses in rat hippocampus are different from receptors mediating cyclic AMP accumulation. Naunyn Schmiedebergs Arch Pharmacol (1984) 1.08
Inhibition by alpha- and beta-adrenoceptors of the twitch response to transmural stimulation in the guinea-pig vas deferens. Eur J Pharmacol (1976) 1.08
Endogenous nitric oxide as a modulator of rabbit skeletal muscle microcirculation in vivo. Br J Pharmacol (1990) 1.08
Adenosine actions and adenosine receptors after 1 week treatment with caffeine. Acta Physiol Scand (1982) 1.07
Reciprocal interactions between adenosine A2A and dopamine D2 receptors in Chinese hamster ovary cells co-transfected with the two receptors. Biochem Pharmacol (1999) 1.07
Presynaptic alpha- and beta-adrenoceptor medicated control of noradrenaline release in human oviduct. Acta Physiol Scand (1975) 1.07
Involvement of adenosine deaminase and adenosine kinase in regulating extracellular adenosine concentration in rat hippocampal slices. Neurochem Int (1995) 1.06
Lipoxins inhibit microvascular inflammatory actions of leukotriene B4. Adv Exp Med Biol (1991) 1.06
Further evidence that prostaglandins inhibit the release of noradrenaline from adrenergic nerve terminals by restriction of availability of calcium. Br J Pharmacol (1976) 1.05
Stimulation of adenosine A1 receptors and bradykinin receptors, which act via different G proteins, synergistically raises inositol 1,4,5-trisphosphate and intracellular free calcium in DDT1 MF-2 smooth muscle cells. Proc Natl Acad Sci U S A (1992) 1.05
Theophylline actions on adenosine receptors. Eur J Respir Dis Suppl (1980) 1.05