5'-Nucleotidase: molecular structure and functional aspects.

PubWeight™: 3.08‹?› | Rank: Top 1%

🔗 View Article (PMC 1132794)

Published in Biochem J on July 15, 1992

Authors

H Zimmermann1

Author Affiliations

1: AK Neurochemie, Zoologisches Institut, J.W. Goethe-Universität, Frankfurt am Main, Federal Republic of Germany.

Articles citing this

(truncated to the top 100)

International Union of Pharmacology LVIII: update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapy. Pharmacol Rev (2006) 5.28

Ecto-5'-nucleotidase (CD73) regulation by hypoxia-inducible factor-1 mediates permeability changes in intestinal epithelia. J Clin Invest (2002) 4.05

Distribution of a glycosylphosphatidylinositol-anchored protein at the apical surface of MDCK cells examined at a resolution of <100 A using imaging fluorescence resonance energy transfer. J Cell Biol (1998) 3.92

The E-NTPDase family of ectonucleotidases: Structure function relationships and pathophysiological significance. Purinergic Signal (2006) 3.52

High-resolution FRET microscopy of cholera toxin B-subunit and GPI-anchored proteins in cell plasma membranes. Mol Biol Cell (2000) 3.37

Purinergic signalling in neuron-glia interactions. Nat Rev Neurosci (2006) 3.17

Physiological roles for ecto-5'-nucleotidase (CD73). Purinergic Signal (2006) 2.98

Structural insight into the mechanism of substrate specificity and catalytic activity of an HD-domain phosphohydrolase: the 5'-deoxyribonucleotidase YfbR from Escherichia coli. J Mol Biol (2008) 2.19

Cellular function and molecular structure of ecto-nucleotidases. Purinergic Signal (2012) 2.13

Impairment of tubuloglomerular feedback regulation of GFR in ecto-5'-nucleotidase/CD73-deficient mice. J Clin Invest (2004) 2.12

Staphylococcus aureus synthesizes adenosine to escape host immune responses. J Exp Med (2009) 1.85

Comparative hydrolysis of P2 receptor agonists by NTPDases 1, 2, 3 and 8. Purinergic Signal (2005) 1.81

Deficiency of CD73/ecto-5'-nucleotidase in mice enhances acute graft-versus-host disease. Blood (2012) 1.72

5'nucleotidase is sorted to the apical domain of hepatocytes via an indirect route. J Cell Biol (1992) 1.65

Loss of ATP diphosphohydrolase activity with endothelial cell activation. J Exp Med (1997) 1.62

Thromboregulatory manifestations in human CD39 transgenic mice and the implications for thrombotic disease and transplantation. J Clin Invest (2004) 1.61

The salivary gland-specific apyrase of the mosquito Aedes aegypti is a member of the 5'-nucleotidase family. Proc Natl Acad Sci U S A (1995) 1.56

Expression of CD39 by human peripheral blood CD4+ CD25+ T cells denotes a regulatory memory phenotype. Am J Transplant (2010) 1.55

Recurrent infections and immune evasion strategies of Staphylococcus aureus. Curr Opin Microbiol (2011) 1.54

Ecto-5'-nucleotidase promotes invasion, migration and adhesion of human breast cancer cells. J Cancer Res Clin Oncol (2007) 1.47

Improved pattern for genome-based screening identifies novel cell wall-attached proteins in gram-positive bacteria. Infect Immun (2001) 1.47

Differential regulation and function of CD73, a glycosyl-phosphatidylinositol-linked 70-kD adhesion molecule, on lymphocytes and endothelial cells. J Cell Biol (1997) 1.46

NT5E mutations that cause human disease are associated with intracellular mistrafficking of NT5E protein. PLoS One (2014) 1.45

Intracellular multiplication and virulence of Shigella flexneri auxotrophic mutants. Infect Immun (1998) 1.36

Effect of shear stress on the release of soluble ecto-enzymes ATPase and 5'-nucleotidase along with endogenous ATP from vascular endothelial cells. Br J Pharmacol (2000) 1.32

Isolated CD39 expression on CD4+ T cells denotes both regulatory and memory populations. Am J Transplant (2009) 1.27

The role of purinergic signaling in the liver and in transplantation: effects of extracellular nucleotides on hepatic graft vascular injury, rejection and metabolism. Front Biosci (2008) 1.24

Ecto-5'-nucleotidase (CD73) inhibits nociception by hydrolyzing AMP to adenosine in nociceptive circuits. J Neurosci (2010) 1.20

Role of VEGF-C and VEGF-D in lymphangiogenesis in gastric cancer. Int J Clin Oncol (2005) 1.11

Extracellular 2,3-cyclic adenosine monophosphate is a potent inhibitor of preglomerular vascular smooth muscle cell and mesangial cell growth [corrected]. Hypertension (2010) 1.10

Mechanism of nitrogen metabolism-related parameters and enzyme activities in the pathophysiology of autism. J Neurodev Disord (2012) 1.06

A deoxyribonucleotidase in mitochondria: involvement in regulation of dNTP pools and possible link to genetic disease. Proc Natl Acad Sci U S A (2000) 1.06

Stimulation of P2 purinergic receptors induces the release of eosinophil cationic protein and interleukin-8 from human eosinophils. Br J Pharmacol (2003) 1.06

Ecto-5'-nucleotidase: Structure function relationships. Purinergic Signal (2006) 1.05

Juxta-articular joint-capsule mineralization in CD73 deficient mice: similarities to patients with NT5E mutations. Cell Cycle (2014) 1.05

Recombinant ecto-5'-nucleotidase (CD73) has long lasting antinociceptive effects that are dependent on adenosine A1 receptor activation. Mol Pain (2010) 1.04

Preferential activation of excitatory adenosine receptors at rat hippocampal and neuromuscular synapses by adenosine formed from released adenine nucleotides. Br J Pharmacol (1996) 1.04

The evidence for two opposite, ATP-generating and ATP-consuming, extracellular pathways on endothelial and lymphoid cells. Biochem J (2002) 1.02

Enzymatic properties of Staphylococcus aureus adenosine synthase (AdsA). BMC Biochem (2011) 1.00

Differential expression of genes related to purinergic signaling in smooth muscle cells, PDGFRα-positive cells, and interstitial cells of Cajal in the murine colon. Neurogastroenterol Motil (2013) 0.97

2',3'-cAMP, 3'-AMP, and 2'-AMP inhibit human aortic and coronary vascular smooth muscle cell proliferation via A2B receptors. Am J Physiol Heart Circ Physiol (2011) 0.96

Purines, the carotid body and respiration. Respir Physiol Neurobiol (2007) 0.96

NT5E CpG island methylation is a favourable breast cancer biomarker. Br J Cancer (2012) 0.96

Expression of the 2',3'-cAMP-adenosine pathway in astrocytes and microglia. J Neurochem (2011) 0.95

Modulation of nucleoside [correction of nucleotide] triphosphate diphosphohydrolase-1 (NTPDase-1)cd39 in xenograft rejection. Mol Med (1999) 0.94

Extracellular 3',5'-cAMP-adenosine pathway inhibits glomerular mesangial cell growth. J Pharmacol Exp Ther (2010) 0.94

Loss of CD73-mediated actin polymerization promotes endometrial tumor progression. J Clin Invest (2015) 0.94

The proteomic landscape of triple-negative breast cancer. Cell Rep (2015) 0.94

Immunocytochemical localization and biochemical characterization of a novel plasma membrane-associated, neutral pH optimum alpha-L-fucosidase from rat testis and epididymal spermatozoa. Biochem J (1996) 0.93

Nucleotidase cascades are catalyzed by secreted proteins of the parasitic nematode Trichinella spiralis. Infect Immun (2002) 0.92

Evidence for control of adenosine metabolism in rat oxidative skeletal muscle by changes in pH. J Physiol (2000) 0.91

Validation and steady-state analysis of a power-law model of purine metabolism in man. Biochem J (1997) 0.91

Anti-CD73 in cancer immunotherapy: awakening new opportunities. Trends Cancer (2016) 0.90

Ecto-5'-nucleotidase: a candidate virulence factor in Streptococcus sanguinis experimental endocarditis. PLoS One (2012) 0.90

The effect of muscle contraction on the regulation of adenosine formation in rat skeletal muscle cells. J Physiol (1999) 0.90

Ecto-5'-nucleotidase (CD73) promotes tumor angiogenesis. Clin Exp Metastasis (2013) 0.90

Distribution of ecto-nucleotidases in mouse sensory circuits suggests roles for nucleoside triphosphate diphosphohydrolase-3 in nociception and mechanoreception. Neuroscience (2011) 0.89

Increased CD39 nucleotidase activity on microparticles from patients with idiopathic pulmonary arterial hypertension. PLoS One (2012) 0.89

Release of the glycosylphosphatidylinositol-anchored enzyme ecto-5'-nucleotidase by phospholipase C: catalytic activation and modulation by the lipid bilayer. Biochem J (1998) 0.89

Extracellular guanosine regulates extracellular adenosine levels. Am J Physiol Cell Physiol (2012) 0.89

Autoimmunity in CD73/Ecto-5'-nucleotidase deficient mice induces renal injury. PLoS One (2012) 0.89

Role of CNPase in the oligodendrocytic extracellular 2',3'-cAMP-adenosine pathway. Glia (2013) 0.89

Extracellular 2',3'-cAMP and 3',5'-cAMP stimulate proliferation of preglomerular vascular endothelial cells and renal epithelial cells. Am J Physiol Renal Physiol (2012) 0.87

Inhibition of CD73 AMP hydrolysis by a therapeutic antibody with a dual, non-competitive mechanism of action. MAbs (2016) 0.87

Ectonucleotidases in Müller glial cells of the rodent retina: Involvement in inhibition of osmotic cell swelling. Purinergic Signal (2007) 0.86

Selective nucleoside triphosphate diphosphohydrolase-2 (NTPDase2) inhibitors: nucleotide mimetics derived from uridine-5'-carboxamide. J Med Chem (2008) 0.86

Structural insights into the inhibition of cytosolic 5'-nucleotidase II (cN-II) by ribonucleoside 5'-monophosphate analogues. PLoS Comput Biol (2011) 0.86

4-Alkyloxyimino derivatives of uridine-5'-triphosphate: distal modification of potent agonists as a strategy for molecular probes of P2Y2, P2Y4, and P2Y6 receptors. J Med Chem (2014) 0.86

Salivary apyrases of Triatoma infestans are assembled into homo-oligomers. Biochem J (2006) 0.85

Purification and some properties of an IMP-specific 5'-nucleotidase from yeast. Biochem J (1994) 0.85

Sphingomyelin phosphodiesterase acid-like 3A (SMPDL3A) is a novel nucleotide phosphodiesterase regulated by cholesterol in human macrophages. J Biol Chem (2014) 0.85

Stimulation of an alpha1-adrenergic receptor downregulates ecto-5' nucleotidase activity on the apical membrane of RPE cells. Purinergic Signal (2006) 0.84

Activation of the glycosyl-phosphatidylinositol-anchored membrane dipeptidase upon release from pig kidney membranes by phospholipase C. Biochem J (1994) 0.84

Ectonucleotidases in tumor cells and tumor-associated immune cells: an overview. J Biomed Biotechnol (2012) 0.83

C-terminal splicing of NTPDase2 provides distinctive catalytic properties, cellular distribution and enzyme regulation. Biochem J (2005) 0.83

Gene sets for utilization of primary and secondary nutrition supplies in the distal gut of endangered Iberian lynx. PLoS One (2012) 0.83

Isolation and characterization of novel, highly proliferative human CD34/CD73-double-positive testis-derived stem cells for cell therapy. Stem Cells Dev (2013) 0.83

Adenosine produced via the CD73/ecto-5'-nucleotidase pathway has no impact on erythropoietin production but is associated with reduced kidney weight. Pflugers Arch (2006) 0.82

Effects of Physical (In)activity on Platelet Function. Biomed Res Int (2015) 0.82

Molecular basis of purinergic signal metabolism by ectonucleotide pyrophosphatase/phosphodiesterases 4 and 1 and implications in stroke. J Biol Chem (2013) 0.82

The extracellular cAMP-adenosine pathway regulates expression of renal D1 dopamine receptors in diabetic rats. J Biol Chem (2011) 0.82

Involvement of A(1) adenosine receptors in osmotic volume regulation of retinal glial cells in mice. Mol Vis (2009) 0.81

Ecto-5'-nucleotidase and thiopurine cellular circulation: association with cytotoxicity. Drug Metab Dispos (2010) 0.81

Developmental disorder associated with increased cellular nucleotidase activity. Proc Natl Acad Sci U S A (1997) 0.81

The nucleoside triphosphate diphosphohydrolase-1/CD39 is incorporated into human immunodeficiency type 1 particles, where it remains biologically active. J Mol Biol (2007) 0.80

Extracellular 2',3'-cAMP-adenosine pathway in proximal tubular, thick ascending limb, and collecting duct epithelial cells. Am J Physiol Renal Physiol (2012) 0.80

Do dental stem cells depict distinct characteristics? - Establishing their "phenotypic fingerprint". Dent Res J (Isfahan) (2014) 0.80

Bovine cytosolic IMP/GMP-specific 5'-nucleotidase: cloning and expression of active enzyme in Escherichia coli. Biochem J (1997) 0.80

Allosteric regulation and substrate activation in cytosolic nucleotidase II from Legionella pneumophila. FEBS J (2014) 0.79

Evidence that [3H]-alpha,beta-methylene ATP may label an endothelial-derived cell line 5'-nucleotidase with high affinity. Br J Pharmacol (1995) 0.79

Role of CD73 in Renal Sympathetic Neurotransmission in the Mouse Kidney. Physiol Rep (2013) 0.79

Adenosine receptor signaling: a key to opening the blood-brain door. Fluids Barriers CNS (2015) 0.79

Host-derived CD4+ T cells attenuate stem cell-mediated transfer of autoimmune arthritis in lethally irradiated C57BL/6.g7 mice. Arthritis Rheum (2013) 0.79

Low-dose levodopa protects nerve cells from oxidative stress and up-regulates expression of pCREB and CD39. PLoS One (2014) 0.78

Biochemical and mass spectrometric characterization of soluble ecto-5'-nucleotidase from bull seminal plasma. Biochem J (2003) 0.78

Modulation of ecto-5'-nucleotidase by phospholipids in human umbilical vein endothelial cells (HUVEC). Naunyn Schmiedebergs Arch Pharmacol (2005) 0.78

Structure-activity relationship of cytoplasmic 5'-nucleotidase substrate sites. Biochem J (1996) 0.77

Immunohistological determination of ecto-nucleoside triphosphate diphosphohydrolase1 (NTPDase1) and 5'-nucleotidase in rat hippocampus reveals overlapping distribution. Cell Mol Neurobiol (2007) 0.77

Multivariate models to detect genomic signatures for a class of drugs: application to thiopurines pharmacogenomics. Pharmacogenomics J (2010) 0.76

B6.g7 mice reconstituted with BDC2·5 non-obese diabetic (BDC2·5NOD) stem cells do not develop autoimmune diabetes. Clin Exp Immunol (2013) 0.76

Articles cited by this

(truncated to the top 100)

Atomic structure of acetylcholinesterase from Torpedo californica: a prototypic acetylcholine-binding protein. Science (1991) 9.91

Extracellular ATP: effects, sources and fate. Biochem J (1986) 8.45

The glycosyl-phosphatidylinositol anchor of membrane proteins. Biochim Biophys Acta (1989) 3.13

Cytochemistry of Golgi fractions prepared from rat liver. J Cell Biol (1974) 3.01

Ecto-enzymes of the guinea pig polymorphonuclear leukocyte. I. Evidence for an ecto-adenosine monophosphatase, adenosine triphosphatase, and -p-nitrophenyl phosphates. J Biol Chem (1974) 2.65

The 5'-nucleotidase of Escherichia coli. I. Purification and properties. J Biol Chem (1967) 2.59

Exfoliation of membrane ecto-enzymes in the form of micro-vesicles. Biochim Biophys Acta (1981) 2.51

Vascular endothelial and smooth muscle cells in culture selectively release adenine nucleotides. Nature (1979) 2.42

Partial purification of a lipoprotein with 5'-nucleotidase activity from membranes of rat liver cells. Proc Natl Acad Sci U S A (1968) 2.37

Glycophospholipid membrane anchoring provides clues to the mechanism of protein sorting in polarized epithelial cells. Trends Biochem Sci (1990) 2.27

Adenosine receptors and calcium: basis for proposing a third (A3) adenosine receptor. Prog Neurobiol (1986) 2.26

Subcellular distribution and movement of 5'-nucleotidase in rat cells. Biochem J (1980) 2.20

Actin-containing matrix associated with the plasma membrane of murine tumour and lymphoid cells. Nature (1981) 2.12

Alternative splicing generates a secreted form of N-CAM in muscle and brain. Cell (1988) 1.97

Metabolism of adenine nucleotides by ectoenzymes of vascular endothelial and smooth-muscle cells in culture. Biochem J (1980) 1.95

Stereoselectivity of ectonucleotidases on vascular endothelial cells. Biochem J (1983) 1.89

Properties of a 5'-nucleotidase purified from mouse liver plasma membranes. Biochem J (1973) 1.85

Physiological roles for adenosine and adenosine 5'-triphosphate in the nervous system. Neuroscience (1981) 1.85

Ectoenzymes of the kidney microvillar membrane. Differential solubilization by detergents can predict a glycosyl-phosphatidylinositol membrane anchor. Biochem J (1988) 1.85

Preparation and properties of 5'-nucleotidase from smooth muscle of small intestine. J Biol Chem (1970) 1.84

Modulation of neurotransmission by purine nucleotides and nucleosides. Biochem Pharmacol (1980) 1.81

Activities and some properties of 5'-nucleotidase, adenosine kinase and adenosine deaminase in tissues from vertebrates and invertebrates in relation to the control of the concentration and the physiological role of adenosine. Biochem J (1978) 1.77

Comparison of butyrylcholinesterase and acetylcholinesterase. Biochem J (1989) 1.77

Uptake of adenosine 5'-monophosphate by Escherichia coli. J Bacteriol (1975) 1.74

Evidence for a continual exchange of 5'-nucleotidase between the cell surface and cytoplasmic membranes in cultured rat fibroblasts. Cell (1982) 1.69

Purification of a phosphatidylinositol-glycan-specific phospholipase C from liver plasma membranes: a possible target of insulin action. Proc Natl Acad Sci U S A (1987) 1.66

A kinetic study of the soluble 5'-nucleotidase of rat liver. Biochem J (1977) 1.62

Specific release of plasma membrane enzymes by a phosphatidylinositol-specific phospholipase C. Biochim Biophys Acta (1978) 1.59

The hydrolysis of extracellular adenine nucleotides by cultured endothelial cells from pig aorta. Feed-forward inhibition of adenosine production at the cell surface. J Biol Chem (1986) 1.57

Production and characterization of monoclonal antibodies to the glycosyl phosphatidylinositol-anchored lymphocyte differentiation antigen ecto-5'-nucleotidase (CD73). Tissue Antigens (1990) 1.57

Bacterial 5-nucleotidase in aquatic ecosystems: a novel mechanism of phosphorus regeneration. Science (1985) 1.55

A phospholipase D specific for the phosphatidylinositol anchor of cell-surface proteins is abundant in plasma. Proc Natl Acad Sci U S A (1988) 1.54

Phosphorylation of 2',3'-dideoxyinosine by cytosolic 5'-nucleotidase of human lymphoid cells. Mol Pharmacol (1989) 1.54

Uridine diphosphate sugar hydrolase. Purification of enzyme and protein inhibitor. J Biol Chem (1967) 1.49

Solubilization and purification of rat liver 5'-nucleotidase by use of a zwitterionic detergent and a monoclonal-antibody immunoadsorbent. Biochem J (1982) 1.44

A NEW CYCLIC PHOSPHODIESTERASE HAVING A 3'-NUCLEOTIDASE ACTIVITY FROM ESCHERICHIA COLI B. I. PURIFICATION AND SOME PROPERTIES OF THE ENZYME. J Biol Chem (1964) 1.41

The distribution of adenosine A1 receptors and 5'-nucleotidase in the brain of some commonly used experimental animals. Neuroscience (1987) 1.39

Ecto-enzymes of the guinea pig polymorphonuclear leukocyte. II. Properties and suitability as markers for the plasma membrane. J Biol Chem (1974) 1.38

Surface localization of 5'-nucleotidase on the mouse lymphocyte. J Histochem Cytochem (1977) 1.38

The 5'-nucleotidases (uridine diphosphate sugar hydrolases) of the Enterobacteriaceae. Biochemistry (1968) 1.37

Biosynthesis, membrane association, and release of N-CAM-120, a phosphatidylinositol-linked form of the neural cell adhesion molecule. J Cell Biol (1987) 1.36

Cytoplasmic 5'-nucleotidase catalyzes acyclovir phosphorylation. J Biol Chem (1985) 1.33

Sheep brain 5'-nucleotidase. Some enzymic properties and allosteric inhibition by nucleoside triphosphates. Biochemistry (1968) 1.33

The control of adenosine concentration in polymorphonuclear leucocytes, cultured heart cells and isolated perfused heart from the rat. Biochem J (1983) 1.32

Metallo-enzymes released from Escherichia coli by osmotic shock. II. Evidence that 5'-nucleotidase and cyclic phosphodiesterase are zinc metallo-enzymes. J Biol Chem (1968) 1.32

The 5'-nucleotidase of Escherichia coli. II. Surface localization and purification of the Escherichia coli 5'-nucleotidase inhibitor. J Biol Chem (1967) 1.31

Nucleotide diphosphate hexose pyrophosphatases. Biochem Biophys Res Commun (1966) 1.30

A cycloheximide-resistant pool of receptors for asialoglycoproteins and mannose 6-phosphate residues in the Golgi complex of hepatocytes. EMBO J (1984) 1.29

Biochemical basis for differential deoxyadenosine toxicity to T and B lymphoblasts: role for 5'-nucleotidase. Proc Natl Acad Sci U S A (1979) 1.28

Isolation and sequence analysis of the gene (cpdB) encoding periplasmic 2',3'-cyclic phosphodiesterase. J Bacteriol (1986) 1.28

Metabolism of Cytokinin : DEPHOSPHORYLATION OF CYTOKININ RIBONUCLEOTIDE BY 5'-NUCLEOTIDASES FROM WHEAT GERM CYTOSOL. Plant Physiol (1981) 1.28

Nucleotide pyrophosphatase, a sialoglycoprotein located on the hepatocyte surface. Nature (1974) 1.28

Effect of theophylline and other drugs on rabbit renal cyclic nucleotide phosphodiesterase, 5'-nucleotidase and adenosine deaminase. Biochem Pharmacol (1978) 1.27

Enzymes of ureide synthesis in pea and soybean. Plant Physiol (1983) 1.26

Primary structure of human placental 5'-nucleotidase and identification of the glycolipid anchor in the mature form. Eur J Biochem (1990) 1.26

Antibodies to 5'-nucleotidase (CD73), a glycosyl-phosphatidylinositol-anchored protein, cause human peripheral blood T cells to proliferate. J Immunol (1989) 1.26

Evidence for the translocation of 5'-nucleotidase across hepatic membranes in vivo. Proc Natl Acad Sci U S A (1975) 1.25

Quantification of endocytosis-derived membrane traffic. Biochim Biophys Acta (1985) 1.25

Ferritin immunoelectron microscopic localization of 5'-nucleotidase on rat liver cell surface. J Cell Biol (1984) 1.24

Rapid subcellular fractionation of the rat liver endocytic compartments involved in transcytosis of polymeric immunoglobulin A and endocytosis of asialofetuin. Biochem J (1987) 1.23

Selective release of plasma-membrane enzymes from rat hepatocytes by a phosphatidylinositol-specific phospholipase C. Biochem J (1980) 1.23

Nucleotide sequence and transcriptional analysis of the E. coli ushA gene, encoding periplasmic UDP-sugar hydrolase (5'-nucleotidase): regulation of the ushA gene, and the signal sequence of its encoded protein product. Nucleic Acids Res (1986) 1.22

A NEW CYCLIC PHOSPHODIESTERASE HAVING A 3'-NUCLEOTIDASE ACTIVITY FROM ESCHERICHIA COLI B. II. FURTHER STUDIES ON SUBSTRATE SPECIFICITY AND MODE OF ACTION OF THE ENZYME. J Biol Chem (1964) 1.21

Purification and some properties of cytosol 5'-nucleotidase from rat liver. Biochim Biophys Acta (1981) 1.20

5'-Nucleotidase from rat heart membranes. Inhibition by adenine nucleotides and related compounds. Biochem J (1985) 1.20

Cholinesterase-like domains in enzymes and structural proteins: functional and evolutionary relationships and identification of a catalytically essential aspartic acid. Proc Natl Acad Sci U S A (1991) 1.19

Phosphatidyl inositol-specific phospholipase C from Clostridium novyi type A. Arch Biochem Biophys (1978) 1.19

The mechanism of adenosine production in rat polymorphonuclear leucocytes. Biochem J (1983) 1.16

A proposal for the role of ecto-enzymes and adenylates in traumatic shock. J Theor Biol (1980) 1.16

5'-Nucleotidase from rat heart. Biochemistry (1981) 1.16

Primary structure of rat liver 5'-nucleotidase deduced from the cDNA. Presence of the COOH-terminal hydrophobic domain for possible post-translational modification by glycophospholipid. J Biol Chem (1990) 1.14

In vitro regulation of rat heart 5'-nucleotidase by adenine nucleotides and magnesium. J Biol Chem (1971) 1.14

5'-Nucleotidase of microglial cells in the facial nucleus during axonal reaction. J Neurocytol (1978) 1.13

Regulation of rat heart cytosol 5'-nucleotidase by adenylate energy charge. Biochem J (1986) 1.12

Purification of a glycosyl-phosphatidylinositol-specific phospholipase D from human plasma. J Biol Chem (1989) 1.11

High Km soluble 5'-nucleotidase from human placenta. Properties and allosteric regulation by IMP and ATP. J Biol Chem (1988) 1.10

Purification of 5'-nucleotidase from human placenta after release from plasma membranes by phosphatidylinositol-specific phospholipase C. Biochem Biophys Res Commun (1987) 1.10

Ecto-5'-nucleotidase expression during human B cell development. An explanation for the heterogeneity in B lymphocyte ecto-5'-nucleotidase activity in patients with hypogammaglobulinemia. J Immunol (1986) 1.10

Interactions of lectins with membrane glycoproteins. Effects of concanavalin A on 5'-nucleotidase. Biochim Biophys Acta (1974) 1.09

Purification and properties of 5'-nucleotidase from lymphocyte plasma membranes. Eur J Biochem (1978) 1.09

Physiological and pharmacological properties of adenosine: therapeutic implications. Life Sci (1991) 1.08

5'-Nucleotidases in rat heart. Evidence for the occurrence of two soluble enzymes with different substrate specificities. Biochem J (1988) 1.08

Nucleoside exchange catalysed by the cytoplasmic 5'-nucleotidase. Biochem J (1982) 1.07

5'-Nucleotidases of chicken gizzard and human pancreatic adenocarcinoma cells are anchored to the plasma membrane via a phosphatidylinositol-glycan. Biochem J (1989) 1.07

Preparation of a low-density species of endocytic vesicle containing immunoglobulin A. Biochem J (1983) 1.07

Characterization of antibodies to the glycosyl-phosphatidylinositol membrane anchors of mammalian proteins. Biochem J (1991) 1.07

Ectoenzymes control adenosine modulation of immunoisolated cholinergic synapses. Nature (1987) 1.05

Recycling of 5'-nucleotidase in a rat hepatoma cell line. EMBO J (1988) 1.03

Distribution of 5'-nucleotidase in human lymphoid tissues. Proc Natl Acad Sci U S A (1979) 1.03

The hydrolysis of extracellular adenine nucleotides by arterial smooth muscle cells. Regulation of adenosine production at the cell surface. J Biol Chem (1989) 1.03

Kinetic properties of cytosol 5'-nucleotidase from chicken liver. Biochim Biophys Acta (1978) 1.03

Absolute rates of adenosine formation during ischaemia in rat and pigeon hearts. Biochem J (1988) 1.02

Membrane-anchoring domain of rat liver 5'-nucleotidase: identification of the COOH-terminal serine-523 covalently attached with a glycolipid. Biochemistry (1990) 1.02

Effects of cytoskeletal perturbant drugs on ecto 5'-nucleotidase, a concanavalin A receptor. J Cell Biol (1979) 1.02

Membrane changes during cartilage maturation. Increase in 5'-nucleotidase and decrease in adenosine inhibition of adenylate cyclase. J Cell Biol (1977) 1.02

The existence and properties of two dimers of rat liver ecto-5'-nucleotidase. Biochem J (1984) 1.01

Purification and properties of 5'-nucleotidase from the membrane of Vibrio costicola, a moderately halophilic bacterium. J Bacteriol (1981) 1.00

The pigeon heart 5'-nucleotidase responsible for ischaemia-induced adenosine formation. Biochem J (1988) 1.00

Periplasmic nucleoside diphosphate sugar hydrolase from Bacillus subtilis. Biochemistry (1970) 0.99

ATP release from affinity-purified rat cholinergic nerve terminals. J Neurochem (1987) 0.99