Published in J Mol Biol on June 15, 1980
Cloning and characterization of the gene for beta-tubulin from a benomyl-resistant mutant of Neurospora crassa and its use as a dominant selectable marker. Mol Cell Biol (1986) 5.16
Structure and expression of the human gene encoding major heat shock protein HSP70. Mol Cell Biol (1985) 4.79
Effect of CpG methylation on Msp I. Nucleic Acids Res (1983) 4.32
Two genes encoding steroid 21-hydroxylase are located near the genes encoding the fourth component of complement in man. Proc Natl Acad Sci U S A (1985) 3.22
Novel features of animal mtDNA evolution as shown by sequences of two rat cytochrome oxidase subunit II genes. Proc Natl Acad Sci U S A (1982) 2.75
Sequence complexity of circular Epstein-Bar virus DNA in transformed cells. J Virol (1981) 2.43
Fragments from both termini of the herpes simplex virus type 1 genome contain signals required for the encapsidation of viral DNA. Nucleic Acids Res (1983) 2.37
Proviral deletions and oncogene base-substitutions in insertionally mutagenized c-myc alleles may contribute to the progression of avian bursal tumors. Proc Natl Acad Sci U S A (1984) 2.02
Characterization of human chromosomal DNA sequences which replicate autonomously in Saccharomyces cerevisiae. Nucleic Acids Res (1984) 1.93
Nucleotide sequence preservation of human mitochondrial DNA. Proc Natl Acad Sci U S A (1985) 1.88
The structure and nucleotide sequence of the 5' end of the human c-myc oncogene. Proc Natl Acad Sci U S A (1983) 1.84
Length heteroplasmy of sturgeon mitochondrial DNA: an illegitimate elongation model. Genetics (1990) 1.65
Messenger RNAs of a strongly-expressed late gene of cowpox virus contain 5'-terminal poly(A) sequences. EMBO J (1987) 1.62
A mammalian mitochondrial serine transfer RNA lacking the "dihydrouridine" loop and stem. Nucleic Acids Res (1980) 1.56
Vicariance biogeography in the Pleistocene and speciation in North American wood warblers: a test of Mengel's model. Proc Natl Acad Sci U S A (1992) 1.55
Characterization of mouse 45S ribosomal RNA subspecies suggests that the first processing cleavage occurs 600 +/- 100 nucleotides from the 5' end and the second 500 +/- 100 nucleotides from the 3' end of a 13.9 kb precursor. Nucleic Acids Res (1985) 1.51
Selective induction of human heat shock gene transcription by the adenovirus E1A gene products, including the 12S E1A product. Mol Cell Biol (1987) 1.40
Molecular characterization of germ-line immunoglobulin A transcripts produced during transforming growth factor type beta-induced isotype switching. Proc Natl Acad Sci U S A (1990) 1.31
Cloning and structure determination of cDNA for cutinase, an enzyme involved in fungal penetration of plants. Proc Natl Acad Sci U S A (1984) 1.30
Identification and genetic mapping of a herpes simplex virus capsid protein that binds DNA. J Virol (1984) 1.21
A genetic discontinuity in a continuously distributed species: mitochondrial DNA in the American oyster, Crassostrea virginica. Genetics (1990) 1.17
A splice junction deletion deficient in the transport of RNA does not polyadenylate nuclear RNA. Mol Cell Biol (1983) 1.16
Mapping of heteroplasmic mitochondrial DNA deletions in Kearns-Sayre syndrome. Nucleic Acids Res (1989) 1.13
Suppressible and nonsuppressible +1 G-C base pair insertions induced by ICR-170 at the his4 locus in Saccharomyces cerevisiae. Mol Cell Biol (1985) 1.12
Cloning, mapping, and sequencing of plasmid R100 traM and finP genes. J Bacteriol (1986) 1.11
Interruption of a human nuclear sequence homologous to mitochondrial DNA by a member of the KpnI 1.8 kb family. Nucleic Acids Res (1984) 1.08
Identification of a provirally activated c-Ha-ras oncogene in an avian nephroblastoma via a novel procedure: cDNA cloning of a chimaeric viral-host transcript. EMBO J (1986) 1.06
The complete nucleotide sequence of a snake (Dinodon semicarinatus) mitochondrial genome with two identical control regions. Genetics (1998) 1.05
Efficient cloning and engineering of entire mitochondrial genomes in Escherichia coli and transfer into transcriptionally active mitochondria. Nucleic Acids Res (2003) 1.03
Properties of some monkey DNA sequences obtained by a procedure that enriches for DNA replication origins. Mol Cell Biol (1985) 1.03
Sensitive analysis of genetic heterogeneity of adenovirus types 3 and 7 in the Soviet Union. J Clin Microbiol (1991) 1.02
Interspersed repetitive and tandemly repetitive sequences are differentially represented in extrachromosomal covalently closed circular DNA of human diploid fibroblasts. Nucleic Acids Res (1985) 0.99
Immunoglobulin diversity: analysis of the germ-line VH gene repertoire of the murine anti-GAT response. Nucleic Acids Res (1983) 0.97
Interstrain conservation of the murine GAT-specific antibody V kappa repertoire as analyzed at the germline gene level. EMBO J (1983) 0.94
DNA orientation using specific avidin-ferritin biotin end labelling. Nucleic Acids Res (1987) 0.84
Purification and characterization of a mammalian endo-exonuclease. Nucleic Acids Res (1992) 0.84
Modifying the Mitochondrial Genome. Cell Metab (2016) 0.78
Frederick Sanger (1918–2013). Genome Res (2014) 0.75
Sequence and organization of the human mitochondrial genome. Nature (1981) 57.39
Transcriptional interference between c-Jun and the glucocorticoid receptor: mutual inhibition of DNA binding due to direct protein-protein interaction. Cell (1990) 6.84
A different genetic code in human mitochondria. Nature (1979) 6.41
The pronatriodilatin gene is located on the distal short arm of human chromosome 1 and on mouse chromosome 4. Am J Hum Genet (1985) 4.01
Different pattern of codon recognition by mammalian mitochondrial tRNAs. Proc Natl Acad Sci U S A (1980) 3.74
Gene structure of human cardiac hormone precursor, pronatriodilatin. Nature (1985) 2.41
A pituitary cell-restricted T box factor, Tpit, activates POMC transcription in cooperation with Pitx homeoproteins. Cell (2001) 2.15
Occurrence of T-cell lymphoma in a patient with Philadelphia chromosome-positive chronic myelogenous leukemia with rearrangements of BCR and TCR-beta genes in the lymph nodes. Am J Hematol (1993) 1.97
Hindlimb patterning and mandible development require the Ptx1 gene. Development (1999) 1.96
A homeodomain gene Ptx3 has highly restricted brain expression in mesencephalic dopaminergic neurons. Proc Natl Acad Sci U S A (1997) 1.83
Novel dimeric Nur77 signaling mechanism in endocrine and lymphoid cells. Mol Cell Biol (1997) 1.80
Ptx1, a bicoid-related homeo box transcription factor involved in transcription of the pro-opiomelanocortin gene. Genes Dev (1996) 1.80
Heterodimerization between members of the Nur subfamily of orphan nuclear receptors as a novel mechanism for gene activation. Mol Cell Biol (1999) 1.68
Egr-1 is a downstream effector of GnRH and synergizes by direct interaction with Ptx1 and SF-1 to enhance luteinizing hormone beta gene transcription. Mol Cell Biol (1999) 1.65
Homeopathic treatment of plantar warts. CMAJ (1992) 1.63
The pan-pituitary activator of transcription, Ptx1 (pituitary homeobox 1), acts in synergy with SF-1 and Pit1 and is an upstream regulator of the Lim-homeodomain gene Lim3/Lhx3. Mol Endocrinol (1998) 1.61
The bicoid-related homeoprotein Ptx1 defines the most anterior domain of the embryo and differentiates posterior from anterior lateral mesoderm. Development (1997) 1.50
NeuroD1/beta2 contributes to cell-specific transcription of the proopiomelanocortin gene. Mol Cell Biol (1997) 1.49
Neuroendocrine dysplasia in mice lacking protein tyrosine phosphatase sigma. Nat Genet (1999) 1.38
Antagonism between Nur77 and glucocorticoid receptor for control of transcription. Mol Cell Biol (1997) 1.31
Developmental stage-specific regulation of atrial natriuretic factor gene transcription in cardiac cells. Mol Cell Biol (1994) 1.30
Most of the coding region of rat ACTH beta--LPH precursor gene lacks intervening sequences. Nature (1980) 1.29
Pituitary pro-opiomelanocortin gene expression requires synergistic interactions of several regulatory elements. Mol Cell Biol (1991) 1.28
Specific protein-protein interaction between basic helix-loop-helix transcription factors and homeoproteins of the Pitx family. Mol Cell Biol (2000) 1.27
Cell-specific helix-loop-helix factor required for pituitary expression of the pro-opiomelanocortin gene. Mol Cell Biol (1993) 1.27
Dopaminergic receptors in the anterior pituitary gland. Correlation of [3H]dihydroergocryptine binding with the dopaminergic control of prolactin release. J Biol Chem (1978) 1.26
Molecular cloning and characterization of DNA sequences encoding rat and human atrial natriuretic factors. Proc Natl Acad Sci U S A (1984) 1.26
The gene for rat atrial natriuretic factor. J Biol Chem (1985) 1.25
Transcriptional properties of Ptx1 and Ptx2 isoforms. Neuroendocrinology (2000) 1.18
Expression of atrial natriuretic factor gene in heart ventricular tissue. Peptides (1987) 1.17
Ptx1 regulates SF-1 activity by an interaction that mimics the role of the ligand-binding domain. EMBO J (1999) 1.16
Pitx3 activates mouse tyrosine hydroxylase promoter via a high-affinity binding site. J Neurochem (2001) 1.15
Glucocorticoid inhibition of transcription from episomal proopiomelanocortin gene promoter. Proc Natl Acad Sci U S A (1986) 1.12
Differential expression of natriuretic peptide genes in cardiac and extracardiac tissues. Mol Endocrinol (1991) 1.11
Structure of the rat pro-opiomelanocortin (POMC) gene. FEBS Lett (1985) 1.09
Tissue-specific activity of the pro-opiomelanocortin gene promoter. Mol Cell Biol (1987) 1.08
Opposite regulation of pro-opiomelanocortin gene transcription by glucocorticoids and CRH. Mol Cell Endocrinol (1985) 1.08
Pituitary-specific expression and glucocorticoid regulation of a proopiomelanocortin fusion gene in transgenic mice. Proc Natl Acad Sci U S A (1988) 1.06
Tissue-specific regulation of pituitary proopiomelanocortin gene transcription by corticotropin-releasing hormone, 3',5'-cyclic adenosine monophosphate, and glucocorticoids. Mol Endocrinol (1987) 1.05
[The effects of Arnica Montana on blood coagulation. Randomized controlled trial]. Can Fam Physician (1993) 1.02
Transient dwarfism and hypogonadism in mice lacking Otx1 reveal prepubescent stage-specific control of pituitary levels of GH, FSH and LH. Development (1998) 1.02
Selective effect of androgens on LH and FSH release in anterior pituitary cells in culture. Endocrinology (1976) 1.01
Pituitary homeobox 1 (Ptx1) is differentially expressed during pituitary development. Endocrinology (1999) 0.99
Distal cis-acting promoter sequences mediate glucocorticoid stimulation of cardiac atrial natriuretic factor gene transcription. J Biol Chem (1991) 0.98
Intracranial plasmacytoma associated with multiple myeloma. Can J Ophthalmol (1984) 0.98
Phenotypic homogeneity and genotypic variability in a large series of congenital isolated ACTH-deficiency patients with TPIT gene mutations. J Clin Endocrinol Metab (2011) 0.96
Somatostatin analogs which inhibit glucagon and growth hormone more than insulin release. Biochem Biophys Res Commun (1977) 0.96
Thrombotic thrombocytopenic purpura following hemorrhagic colitis due to Escherichia coli O157:H7. Am J Med (1990) 0.95
Complete structure of the porcine pro-opiomelanocortin mRNA derived from the nucleotide sequence of cloned cDNA. Nucleic Acids Res (1983) 0.94
Inhibition of adenosine 3',5'-monophosphate accumulation in anterior pituitary gland in vitro by growth hormone-release inhibiting hormone. Biochem Biophys Res Commun (1974) 0.94
Human and murine PTX1/Ptx1 gene maps to the region for Treacher Collins syndrome. Mamm Genome (1997) 0.93
Characteristics of the interaction between thyrotropin-releasing hormone and somatostatin for thyrotropin and prolactin release. Endocrinology (1976) 0.92
Unusual proopiomelanocortin ribonucleic acids in extrapituitary tissues: intronless transcripts in testes and long poly(A) tails in hypothalamus. Mol Endocrinol (1987) 0.92
Modulation of pituitary thyrotropin releasing hormone receptor levels by estrogens and thyroid hormones. Endocrinology (1977) 0.89
XhoI polymorphism at the human pronatriodilatin (hPND) gene locus. Nucleic Acids Res (1986) 0.89
Mechanism of action of hypothalamic hormones in the adenohypophysis. Annu Rev Physiol (1979) 0.88
Interactions between 17 beta-estradiol and progesterone in the control of luteinizing hormone and follicle-stimulating hormone release in rat anterior pituitary cells in culture. Endocrinology (1981) 0.88
Blood monocytes from most human immunodeficiency virus type 1-infected patients do not carry proviral DNA. Clin Diagn Lab Immunol (1994) 0.87
Specificity of the stimulatory effect of prostaglandins on hormone release in rat anterior pituitary cells in culture. Prostaglandins (1976) 0.87
Estradiol-induced increase of the LH responsive to LH releasing hormone (LHRH) in rat anterior pituitary cells in culture. Endocrinology (1976) 0.87
Thrombospondin binds to the surface of human osteosarcoma cells and mediates platelet-osteosarcoma cell interaction. Cancer Res (1991) 0.83
Combined intraommaya methotrexate, cytosine arabinoside, hydrocortisone and thio-TEPA for meningeal involvement by malignancies. J Neurooncol (1987) 0.83
Primary thrombocythemia in pregnancy: a report of two cases. Am J Obstet Gynecol (1988) 0.83
Ventricles as a major site of atrial natriuretic factor synthesis and release in cardiomyopathic hamsters with heart failure. Circ Res (1989) 0.82
Mechanism of action of hypothalamic hormones in the anterior pituitary gland and specific modulation of their activity by sex steroids and thyroid hormones. Recent Prog Horm Res (1978) 0.82
Independent glucocorticoid induction and repression of two contiguous responsive genes. Mol Cell Biol (1989) 0.82
Inhibition of growth hormone and thyrotropin release by growth hormone-release inhibiting hormone. Mol Cell Endocrinol (1974) 0.81
Molecular determinants for cell specificity and glucocorticoid repression of the proopiomelanocortin gene. Ann N Y Acad Sci (1993) 0.81
Role of cyclic AMP in the action of hypothalamic regulatory hormones. Adv Cyclic Nucleotide Res (1975) 0.80
New aspects of the mechanism of action of hypothalamic regulatory hormones. Curr Top Mol Endocrinol (1976) 0.80
Hodgkin's disease in CLL. Am J Hematol (1995) 0.80
TaqI polymorphism at the 3' end of the human pronatriodilatin gene (hPND). Nucleic Acids Res (1986) 0.80
Repression of virus-induced interferon A promoters by homeodomain transcription factor Ptx1. Mol Cell Biol (2000) 0.79
Effect of gonadal steroids on the luteinizing hormone and follicle-stimulating hormone response to 8-bromo-adenosine 3',5'-monophosphate in anterior pituitary cells in culture. Endocrinology (1978) 0.79
Opposite ability of pre-TCR and alpha beta TCR to induce apoptosis. J Immunol (2001) 0.79
Cloning and expression of the atrial natriuretic factor gene. Clin Physiol Biochem (1988) 0.78
Ventricular activation of the atrial natriuretic factor gene in acute myocardial infarction. N Engl J Med (1988) 0.78
Lung is an important source of atrial natriuretic factor in experimental cardiomyopathy. J Clin Invest (1989) 0.77
Glycoprotein I is not involved in aggregation of platelets by wheat germ agglutinin (WGA). Thromb Res (1981) 0.77
Effects of low-impact, moderate-intensity exercise training with and without wrist weights on functional capacities and mood states in older adults. Gerontology (1998) 0.77
Characterization of MENX-associated pituitary tumours. Neuropathol Appl Neurobiol (2013) 0.77
Characterization of novel platelet and endothelial cell target antigens in a family with genetic susceptibility to autoimmunity. Am J Hematol (1991) 0.77
Plasmodium falciparum malaria mimicking autoimmune hemolytic anemia during pregnancy. Can Med Assoc J (1985) 0.77
Mechanism of action of luteinizing hormone releasing hormone and thyrotropin releasing hormone in the anterior pituitary gland and modulation of their activity by peripheral hormones. Adv Exp Med Biol (1977) 0.77
A neonatal form of isolated ACTH deficiency frequently associated with Tpit gene mutations. Endocr Res (2004) 0.76
Identification of novel factor VIII inhibitor epitopes using synthetic peptide arrays. Vox Sang (1997) 0.76
Atrial natriuretic factor in the impulse-conduction system of rat cardiac ventricles. Cell Tissue Res (1989) 0.76
Morphometric analysis of platelets in Bernard-Soulier syndrome: size and configuration in patients and carriers. Thromb Haemost (1984) 0.76
Role of platelet membrane glycoproteins Ib/IX and IIb/IIIa, and of platelet alpha-granule proteins in platelet aggregation induced by human osteosarcoma cells. Cancer Res (1993) 0.76
Cloning and functional expression of the bovine natriuretic peptide receptor-B (natriuretic factor R1c subtype. Mol Cell Biochem (1994) 0.76
[Not Available]. Can Fam Physician (1987) 0.75
Author's reply to "Rearrangement of the BCR/ABL and TCR-beta genes in lymph node blast crisis diagnosed of chronic myeloid leukemia". Am J Hematol (1994) 0.75
Women and work: the more, the better? Can Fam Physician (1984) 0.75
Absence of human T-lymphotropic virus types I and II infection in an Ontario hemophilia population. Transfusion (1992) 0.75
A multinational evaluation of the efficacy, safety and acceptability of the Protectaid contraceptive sponge. Eur J Contracept Reprod Health Care (2001) 0.75
Characterization of a partial prostaglandin endoperoxide H synthase-1 deficiency in a patient with a bleeding disorder. Br J Haematol (2001) 0.75
[Expression of the gene for the atrial natriuretic factor: a marker for ventricular hypertrophy]. Union Med Can (1988) 0.75
Characterization of reticulofibroblastoid colonies (CFU-RF) derived from bone marrow and long-term marrow culture monolayers. J Cell Physiol (1986) 0.75
Expression and mutation analysis of Tpit in the canine pituitary gland and corticotroph adenomas. Domest Anim Endocrinol (2007) 0.75