Published in Proc Natl Acad Sci U S A on September 01, 1980
Construction of live vaccines using genetically engineered poxviruses: biological activity of vaccinia virus recombinants expressing the hepatitis B virus surface antigen and the herpes simplex virus glycoprotein D. Proc Natl Acad Sci U S A (1984) 3.58
Transcription of the hepatitis B surface antigen gene in mouse cells transformed with cloned viral DNA. J Virol (1982) 3.51
Replicative intermediates of hepatitis B virus in HepG2 cells that produce infectious virions. J Virol (1988) 3.21
Production of hepatitis B virus in vitro by transient expression of cloned HBV DNA in a hepatoma cell line. EMBO J (1987) 3.09
Stable expression and replication of hepatitis B virus genome in an integrated state in a human hepatoma cell line transfected with the cloned viral DNA. Proc Natl Acad Sci U S A (1987) 3.05
Amplification of expression of hepatitis B surface antigen in 3T3 cells cotransfected with a dominant-acting gene and cloned viral DNA. Proc Natl Acad Sci U S A (1982) 2.20
Infectious hepatitis B virus from cloned DNA of known nucleotide sequence. Proc Natl Acad Sci U S A (1985) 2.20
Hepatitis B virus infection of adult human hepatocytes cultured in the presence of dimethyl sulfoxide. J Virol (1988) 2.11
Cloned duck hepatitis B virus DNA is infectious in Pekin ducks. J Virol (1984) 1.80
Expression of hepatitis B antigens with a simian virus 40 vector. J Virol (1984) 1.80
Replication and gene expression of hepatitis B virus in a transgenic mouse that contains the complete viral genome. J Virol (1988) 1.68
Expression of hepatitis B virus surface antigen gene in cultured cells by using recombinant plasmid vectors. Mol Cell Biol (1983) 1.56
Hepatitis B virus surface antigen impairs myeloid dendritic cell function: a possible immune escape mechanism of hepatitis B virus. Immunology (2008) 1.31
The gene S promoter of hepatitis B virus confers constitutive gene expression. Nucleic Acids Res (1983) 1.23
Expression of hepatitis B surface antigen in unselected cell culture transfected with recircularized HBV DNA. EMBO J (1982) 1.21
Secretion of the hepatitis B virus surface antigen from mouse cells using an extra-chromosomal eucaryotic vector. EMBO J (1983) 1.19
Enhanced production of hepatitis B surface antigen in NIH 3T3 mouse fibroblasts by using extrachromosomally replicating bovine papillomavirus vector. Mol Cell Biol (1983) 1.09
Late transient expression of human hepatitis B virus genes in monkey cells. EMBO J (1983) 0.97
A chronic carrierlike state is established in nude mice injected with cloned hepatitis B virus DNA. J Virol (1988) 0.90
Improved method for rapid and efficient determination of genome replication and protein expression of clinical hepatitis B virus isolates. J Clin Microbiol (2011) 0.88
Interaction of mutant hepatitis B X protein with p53 tumor suppressor protein affects both transcription and cell survival. Mol Carcinog (2011) 0.84
IFN-CSP inhibiting hepatitis B virus in HepG2.2.15 cells involves JAK-STAT signal pathway. Biomed Res Int (2015) 0.83
Viral nanoparticles as macromolecular devices for new therapeutic and pharmaceutical approaches. Int J Physiol Pathophysiol Pharmacol (2010) 0.78
Antisense oligonucleotide targeting at the initiator of hTERT arrests growth of hepatoma cells. World J Gastroenterol (2004) 0.77
An N-terminal extension to the hepatitis B virus core protein forms a poorly ordered trimeric spike in assembled virus-like particles. J Struct Biol (2014) 0.75
The regulation of proteins associated with the cytoskeleton by hepatitis B virus X protein during hepatocarcinogenesis. Oncol Lett (2017) 0.75
A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology (1973) 127.36
Rat insulin genes: construction of plasmids containing the coding sequences. Science (1977) 17.05
Nucleotide sequence of the hepatitis B virus genome (subtype ayw) cloned in E. coli. Nature (1979) 15.42
Virus-like particles in serum of patients with Australia-antigen-associated hepatitis. Lancet (1970) 11.61
Hepatitis B virus genes and their expression in E. coli. Nature (1979) 10.83
Genome of hepatitis B virus: restriction enzyme cleavage and structure of DNA extracted from Dane particles. Proc Natl Acad Sci U S A (1975) 6.68
Nucleotide sequence of the gene coding for the major protein of hepatitis B virus surface antigen. Nature (1979) 6.10
New antigen-antibody system in Australia-antigen-positive hepatitis. Lancet (1971) 5.41
Cloning in Escherichia coli and physical structure of hepatitis B virion DNA. Proc Natl Acad Sci U S A (1979) 4.71
Prevalence of hepatitis B virus antigen as revealed by direct radioimmune assay with 125 I-antibody. J Immunol (1972) 4.25
Cloning and endonuclease mapping of the hepatitis B viral genome. Nature (1979) 3.62
Expression in Escherichia coli of hepatitis B virus DNA sequences cloned in plasmid pBR322. Nature (1979) 3.03
Demonstration of hepatitis B e antigen in the core of Dane particles. J Immunol (1979) 2.56
Tumor initiators and promoters in the induction of Epstein-Barr virus. Proc Natl Acad Sci U S A (1979) 2.55
The genome of hepatitis B virus. Annu Rev Microbiol (1977) 2.31
Purification of naked intranuclear particles from human liver infected by hepatitis B virus. Proc Natl Acad Sci U S A (1974) 1.33
Serotypes of hepatitis B antigen (HBs Ag): the problem of "new" determinants, as exemplified by "t". Am J Med Sci (1976) 1.15
Tumour promoter TPA enhances transformation of human leukocytes by Epstein-Barr virus. Nature (1979) 1.11
Retinoic acid inhibition of Epstein-Barr virus induction. Nature (1979) 1.09
Association of hepatitis B e-antigen (HBeAg) determinants with the core of Dane particles. J Gen Virol (1979) 0.97
Ionic requirements of the DNA polymerase associated with serum hepatitis B antigen. J Infect Dis (1977) 0.84
The hepatitis B virus and its DNA polymerase: the prototype three-D virus. Mol Cell Biochem (1979) 0.83
Production of hepatitis B virus particles in Hep G2 cells transfected with cloned hepatitis B virus DNA. Proc Natl Acad Sci U S A (1987) 8.11
Severe acquired immunodeficiency in male homosexuals, manifested by chronic perianal ulcerative herpes simplex lesions. N Engl J Med (1981) 5.44
Inhibition of DNA methyltransferase and induction of Friend erythroleukemia cell differentiation by 5-azacytidine and 5-aza-2'-deoxycytidine. J Biol Chem (1982) 3.48
A neighbor-interaction analysis of the hypochromism and spectra of DNA. J Mol Biol (1965) 3.24
Replicative intermediates of hepatitis B virus in HepG2 cells that produce infectious virions. J Virol (1988) 3.21
Prospective randomised trial of single and multifraction radiotherapy schedules in the treatment of painful bony metastases. Radiother Oncol (1986) 3.07
The assessment of antiangiogenic and antivascular therapies in early-stage clinical trials using magnetic resonance imaging: issues and recommendations. Br J Cancer (2005) 2.85
ISOLATION OF ADENOSINE AMINO ACID ESTERS FROM A RIBONUCLEASE DIGEST OF SOLUBLE, LIVER RIBONUCLEIC ACID. Proc Natl Acad Sci U S A (1958) 2.61
The mechanisms of reovirus uncoating and gene activation in vivo. Virology (1972) 2.60
How should we introduce clinical PET in the UK? The oncologists need to have a view. Clin Oncol (R Coll Radiol) (2004) 2.56
Hepatitis B virus produced by transfected Hep G2 cells causes hepatitis in chimpanzees. Proc Natl Acad Sci U S A (1987) 2.46
Asynchronous synthesis of the complementary strands of the reovirus genome. Proc Natl Acad Sci U S A (1971) 2.42
Quantitative microassay in cell culture for enterotoxin of Shigella dysenteriae. J Infect Dis (1972) 2.40
Cefamandole: antimicrobial activity in vitro of a new cephalosporin. Antimicrob Agents Chemother (1975) 2.38
Immune restoration disease after the treatment of immunodeficient HIV-infected patients with highly active antiretroviral therapy. HIV Med (2000) 2.37
Simplified chromatographic separation of immunoglobulin M from G and its application to toxoplasma indirect immunofluorescence. J Clin Microbiol (1979) 2.22
Amplification of expression of hepatitis B surface antigen in 3T3 cells cotransfected with a dominant-acting gene and cloned viral DNA. Proc Natl Acad Sci U S A (1982) 2.20
Determination of DNA composition and concentration by spectral analysis. J Mol Biol (1966) 2.12
Four base-specific nucleoside 5'-triphosphatases in the subviral core of reovirus. Nature (1970) 1.96
Protein initiation in eukaryotes: formation and function of a ternary complex composed of a partially purified ribosomal factor, methionyl transfer RNA, and guanosine triphosphate. Proc Natl Acad Sci U S A (1973) 1.83
Non-surgical management of early breast cancer in the United Kingdom: radiotherapy fractionation practices. Clinical Audit Sub-committee of the Faculty of Clinical Oncology, Royal College of Radiologists, and the Joint Council for Clinical Oncology. Clin Oncol (R Coll Radiol) (1995) 1.82
Properties of RNA transcriptase in reovirus subviral particles. Proc Natl Acad Sci U S A (1970) 1.82
Bloodstream infections in the elderly. Am J Med (1989) 1.80
Regulation of interleukin-6 expression in cultured human blood monocytes and monocyte-derived macrophages. Blood (1988) 1.76
The reovirus replicative cycle: conservation of parental RNA and protein. Proc Natl Acad Sci U S A (1970) 1.76
AMINO ACID INCORPORATION IN PIGEON PANCREAS FRACTIONS. Proc Natl Acad Sci U S A (1958) 1.74
The reovirus replicative cycle. Annu Rev Biochem (1976) 1.68
Pharmacological studies with cefamandole in human volunteers. Antimicrob Agents Chemother (1976) 1.68
Pharmacologic studies on tobramycin and comparison with gentamicin. J Clin Pharmacol New Drugs (1972) 1.66
Purification and characterization of a cellular fibrinolytic factor associated with oncogenic transformation: the plasminogen activator from SV-40-transformed hamster cells. Biochim Biophys Acta (1974) 1.65
Cephanone: in vitro antibacterial activity and pharmacology in normal human volunteers. Antimicrob Agents Chemother (1972) 1.64
Comparison of the antibacterial activities of sisomicin and gentamicin against gram-negative bacteria. Antimicrob Agents Chemother (1975) 1.62
Antimicrobial activity in vitro of netilmicin and comparison with sisomicin, gentamicin, and tobramycin. Antimicrob Agents Chemother (1977) 1.58
Suppression of thromboxane A2 but not of systemic prostacyclin by controlled-release aspirin. N Engl J Med (1991) 1.58
Correlation between hypomethylation of DNA and expression of globin genes in Friend erythroleukemia cells. Eur J Biochem (1977) 1.57
Renal aspergilloma: an unusual cause of infection in a patient with the acquired immunodeficiency syndrome. Am J Med (1992) 1.56
Tobramycin: in vitro antibacterial spectrum of a new aminoglycoside. J Clin Pharmacol New Drugs (1972) 1.55
Does fluorine-18 fluorodeoxyglucose metabolic imaging of tumours benefit oncology? Eur J Nucl Med (1997) 1.55
Inhibition of the replication of hepatitis B virus by the carbocyclic analogue of 2'-deoxyguanosine. Proc Natl Acad Sci U S A (1989) 1.54
Protein synthesis initiation in eukaryotes. Characterization of ribosomal factors from mouse fibroblasts. J Biol Chem (1973) 1.53
The cost-effectiveness of wound management protocols of care. Br J Nurs (2000) 1.52
An assessment of clinically optimal gold marker length and diameter for pelvic radiotherapy verification using an amorphous silicon flat panel electronic portal imaging device. Br J Radiol (2005) 1.50
Cephapirin: in vitro antibacterial spectrum. Appl Microbiol (1971) 1.50
Coping style and depression influence the healing of diabetic foot ulcers: observational and mechanistic evidence. Diabetologia (2010) 1.47
Mechanism of reovirus double-stranded ribonucleic acid synthesis in vivo and in vitro. J Virol (1971) 1.47
Staphylococcal IgE antibodies, hyperimmunoglobulinemia E and Staphylococcus aureus infections. N Engl J Med (1979) 1.47
Selective inhibition of ribosomal RNA synthesis in mammalian cells. Biochim Biophys Acta (1968) 1.45
Influence of dietary protein restriction on immune competence. II. Effect on lymphoid tissue. Clin Exp Immunol (1976) 1.40
Central nervous system infections in the elderly. Arch Intern Med (1989) 1.40
Prevalence of and risk factors for HIV-associated neuropathy in Melbourne, Australia 1993-2006. HIV Med (2007) 1.40
Recognizing the feet as being at risk from pressure damage. Br J Nurs (2002) 1.38
Evaluation of quality of contents of general practice records. Br Med J (Clin Res Ed) (1984) 1.38
Cephapirin: pharmacology in normal human volunteers. J Clin Pharmacol New Drugs (1972) 1.36
Age and height predict neuropathy risk in patients with HIV prescribed stavudine. Neurology (2009) 1.35
Comparative study of piperacillin, ticarcillin, and carbenicillin pharmacokinetics. Antimicrob Agents Chemother (1980) 1.35
Purification of naked intranuclear particles from human liver infected by hepatitis B virus. Proc Natl Acad Sci U S A (1974) 1.33
Hypomethylation of DNA during differentiation of Friend erythroleukemia cells. J Cell Biol (1980) 1.30
Infection due to Actinobacillus actinomycetemcomitans. Am J Clin Pathol (1971) 1.30
Pharmacology of cefazolin in human volunteers. J Clin Pharmacol (1973) 1.29
Pharmacokinetic study of netilmicin. Antimicrob Agents Chemother (1977) 1.28
Regulation of the reovirus RNA transcriptase by a viral capsomere protein. Virology (1972) 1.27
Infections caused by microorganisms of the genus Erwinia. Ann Intern Med (1972) 1.27
D.N.A. polymerase in preparations containing Australia antigen. Lancet (1971) 1.27
Assessment of antiangiogenic and antivascular therapeutics using MRI: recommendations for appropriate methodology for clinical trials. Br J Radiol (2003) 1.27
Parametric image reconstruction using spectral analysis of PET projection data. Phys Med Biol (1998) 1.26
Levels of IL-6 and soluble IL-6 receptor are increased in HIV patients with a history of immune restoration disease after HAART. HIV Med (2002) 1.26
Identification of protein-binding sites in the hepatitis B virus enhancer and core promoter domains. Mol Cell Biol (1988) 1.26
Endocarditis caused by Lactobacillus plantarum. Ann Intern Med (1973) 1.25
Syphilitic osteomyelitis with diffusely abnormal bone scan. Mt Sinai J Med (1979) 1.25
The role of D-1 and D-2 receptors. Nature (1980) 1.24
The toxicity of inactivated bacteria and endotoxin in mice suffering from protein malnutrition. J Reticuloendothel Soc (1975) 1.23
Expression of RANKL and OPG mRNA in periodontal disease: possible involvement in bone destruction. Int J Mol Med (2003) 1.21
64Cu metabolism in Menkes and normal cultured skin fibroblasts. Pediatr Res (1978) 1.21
Characterization of functional vanilloid receptors expressed by mast cells. Blood (1998) 1.21
Pharmacologic studies with cefaclor, a new oral cephalosporin. J Clin Pharmacol (1978) 1.20
Pharmacokinetics of ampicillin-sulbactam in healthy elderly and young volunteers. Antimicrob Agents Chemother (1991) 1.19
Mycobacterial meningitis. Retrospective analysis from 1970 to 1983. Am J Med (1985) 1.19
Immunohistochemical distribution of c-erbB-2 in infiltrating and in situ breast cancer. Int J Cancer (1988) 1.19
Clinical study of the use of the new aminoglycoside tobramycin for therapy of infections due to gram-negative bacteria. Antimicrob Agents Chemother (1974) 1.17
Formation of highly stable complexes between 5-azacytosine-substituted DNA and specific non-histone nuclear proteins. Implications for 5-azacytidine-mediated effects on DNA methylation and gene expression. J Biol Chem (1985) 1.16
Morphologic, immunohistochemical, and ultrastructural studies of the production of hepatitis B virus in vitro. Lab Invest (1988) 1.15
Drug quantitation on a benchtop liquid chromatography-tandem mass spectrometry system. J Chromatogr A (1997) 1.15
Clostridium difficile diarrhea induced by cancer chemotherapy. Arch Intern Med (1992) 1.15
Degradation of ribonucleic acid in mouse fibroblasts treated with actinomycin. J Cell Biol (1965) 1.14
The direct calculation of parametric images from dynamic PET data using maximum-likelihood iterative reconstruction. Phys Med Biol (1997) 1.14
Coxsackie virus myopericarditis. A microbiological and clinical review. Am J Cardiol (1974) 1.13
Regulation of interleukin 6 receptor expression in human monocytes and monocyte-derived macrophages. Comparison with the expression in human hepatocytes. J Exp Med (1989) 1.13
Immunological profiles of immune restoration disease presenting as mycobacterial lymphadenitis and cryptococcal meningitis. HIV Med (2008) 1.12
Inhibition of dimethyl sulfoxide-stimulated Friend cell erythrodifferentiation by hydrocortisone and other steroids. Proc Natl Acad Sci U S A (1978) 1.11
Outcomes in controlled and comparative studies on non-healing wounds: recommendations to improve the quality of evidence in wound management. J Wound Care (2010) 1.09
Common HLA-B8-DR3 haplotype in Northern India is different from that found in Europe. Tissue Antigens (2002) 1.09
Antimicrobial activity of cefamandole against Salmonella typhi. Antimicrob Agents Chemother (1977) 1.09
Species composition and seasonal abundance of stink bugs (Hemiptera: Pentatomidae) in Louisiana soybean. Environ Entomol (2013) 1.09
The effect of toyocamycin on cellular RNA synthesis. Biochim Biophys Acta (1969) 1.09