Published in Biochemistry on March 31, 1981
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Antisense probing of the human U4/U6 snRNP with biotinylated 2'-OMe RNA oligonucleotides. Cell (1989) 2.68
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A sensitive and convenient micromethod for estimation of urea, citrulline, and carbamyl derivatives. Anal Biochem (1966) 2.36
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A new linkage for solid phase synthesis of oligodeoxyribonucleotides. Nucleic Acids Res (1985) 1.90
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The concept and use of flux measurements in enzyme studies. A theoretical analysis. Arch Biochem Biophys (1966) 1.84
Antisense probes containing 2-aminoadenosine allow efficient depletion of U5 snRNP from HeLa splicing extracts. Nucleic Acids Res (1991) 1.78
Mapping U2 snRNP--pre-mRNA interactions using biotinylated oligonucleotides made of 2'-OMe RNA. EMBO J (1989) 1.73
A comparison of the associations between seven hemostatic or inflammatory variables and coronary heart disease. J Thromb Haemost (2007) 1.69
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How glutaminyl-tRNA synthetase selects glutamine. Structure (1998) 1.60
Kinetic specificity in papain-catalysed hydrolyses. Biochem J (1971) 1.60
Relative frequency of mutations causing ornithine transcarbamylase deficiency in 78 families. Hum Genet (1996) 1.56
Formation of precise connections in the olfactory bulb occurs in the absence of odorant-evoked neuronal activity. Neuron (2000) 1.52
Design of a primer for ribosomal DNA internal transcribed spacer with enhanced specificity for ascomycetes. J Biotechnol (1999) 1.46
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The location of the active-site histidine residue in the primary sequence of papain. Biochem J (1968) 1.44
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Autologous peripheral blood stem cell transplantation (PBSCT) mobilized with G-CSF in AML in first complete remission. Role of intensification therapy in outcome. Bone Marrow Transplant (1998) 1.40
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Investigation of the active site of papain with fluorescent probes. Biochem J (1973) 1.30
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Beta-lactamase inhibitors. The inhibition of serine beta-lactamases by specific boronic acids. Biochem J (1988) 1.29
Amino acid requirements of the nucleocapsid protein of HIV-1 for increasing catalytic activity of a Ki-ras ribozyme in vitro. J Mol Biol (1994) 1.29
Synthesis and applications of oligoribonucleotides with selected 2'-O-methylation using the 2'-O-[1-(2-fluorophenyl)-4-methoxypiperidin-4-yl] protecting group. Nucleic Acids Res (1990) 1.28
A protected biotin containing deoxycytidine building block for solid phase synthesis of biotinylated oligonucleotides. Nucleic Acids Res (1990) 1.28
Association of IL-10 polymorphism with severity of illness in community acquired pneumonia. Thorax (2003) 1.28
Comparative evaluation of seven oligonucleotide analogues as potential antisense agents. J Med Chem (1993) 1.27
Methods of determining rate constants in single-substrate-single-product enzyme reactions. Use of induced transport: limitations of product inhibition. Biochem J (1973) 1.26
The amino acid sequence around the active-site cysteine and histidine residues, and the buried cysteine residue in ficin. Biochem J (1970) 1.26
Completion of the amino acid sequence of papain. Biochem J (1969) 1.24
Target-specific arrest of mRNA translation by antisense 2'-O-alkyloligoribonucleotides. Nucleic Acids Res (1994) 1.24
The synthesis of protected 5'-amino-2',5'-dideoxyribonucleoside-3'-O-phosphoramidites; applications of 5'-amino-oligodeoxyribonucleotides. Nucleic Acids Res (1987) 1.23
Sequence-specific affinity selection of mammalian splicing complexes. Nucleic Acids Res (1990) 1.22
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Human Dermo-1 has attributes similar to twist in early bone development. Bone (2000) 1.20
BEAM chemotherapy followed by autologous stem cell support in lymphoma patients: analysis of efficacy, toxicity and prognostic factors. Bone Marrow Transplant (1997) 1.19
pH-dependence and structure-activity relationships in the papain-catalysed hydrolysis of anilides. Biochem J (1971) 1.19
A synthetic, chemically modified ribozyme eliminates amelogenin, the major translation product in developing mouse enamel in vivo. EMBO J (1995) 1.18
Adolescent drinking behaviour and family socialization factors: a meta-analysis. J Adolesc (1991) 1.17
Homogenous crystalline phosphoglycerate phosphomutase of high activity. A simple method for lysis of yeast. Biochim Biophys Acta (1968) 1.16
Effects of interleukin-12 on the immune response to a multipeptide vaccine for resected metastatic melanoma. J Clin Oncol (2001) 1.16
The synthesis of protected 5'-mercapto-2',5'-dideoxyribonucleoside-3'-O-phosphoramidites; uses of 5'-mercapto-oligodeoxyribonucleotides. Nucleic Acids Res (1987) 1.16
Influence of salt, substrate, and cofactor concentrations on the kinetic and mechanistic behavior of phosphoglycerate mutase. Biochemistry (1968) 1.15
Mechanism of action of 2,3-diphosphoglycerate-independent phosphoglycerate mutase. Biochemistry (1971) 1.14
Fluxes in passive, monovalent and polyvalent carrier systems. J Theor Biol (1966) 1.14
Acute Chagas' disease in a recipient of a bone marrow transplant in Spain: case report. Clin Infect Dis (1992) 1.13
Chemical synthesis of a gene for somatomedin C. Nucleic Acids Res (1985) 1.13
Phosphatidylinositol synthase and phosphatidylinositol/inositol exchange reactions in turkey erythrocyte membranes. Biochem J (1991) 1.13
Antisense probes targeted to an internal domain in U2 snRNP specifically inhibit the second step of pre-mRNA splicing. Nucleic Acids Res (1992) 1.12
Communications. Arch Biochem Biophys (1967) 1.11
Hen egg white lysozyme expressed in, and secreted from, Aspergillus niger is correctly processed and folded. Biotechnology (N Y) (1990) 1.09
Highly efficient oligodeoxyribonucleotide synthesis using fully base protected phosphodiester building blocks carrying 2-(1-methylimidazol-2-yl) phenyl protection of the phosphate. Nucleic Acids Res (1986) 1.09
High-dose therapy in diffuse large cell lymphoma: results and prognostic factors in 452 patients from the GEL-TAMO Spanish Cooperative Group. Ann Oncol (2003) 1.08
The amino acid sequence around the active-site cysteine and histidine residues of stem bromelain. Biochem J (1970) 1.07
Interaction of pyrimethamine, cycloguanil, WR99210 and their analogues with Plasmodium falciparum dihydrofolate reductase: structural basis of antifolate resistance. Bioorg Med Chem (2000) 1.07
Prominent role of lysosomes in the proteolysis of rat liver mitochondria at neutral pH. FEBS Lett (1977) 1.07
[Achondroplasia: molecular study of 28 patients]. Med Clin (Barc) (1998) 1.06
Alcohol misuse prevention for young people: a systematic review reveals methodological concerns and lack of reliable evidence of effectiveness. Addiction (1997) 1.06
A reinvestigation of residues 64-68 and 175 in papain. Evidence that residues 64 and 175 are asparagine. Biochem J (1970) 1.05
Suppression of odorant responses by odorants in olfactory receptor cells. Science (1994) 1.04
Extending the cleavage rules for the hammerhead ribozyme: mutating adenosine15.1 to inosine15.1 changes the cleavage site specificity from N16.2U16.1H17 to N16.2C16.1H17. Nucleic Acids Res (1998) 1.04
The purification and properties of phosphoglycerate mutase from chicken breast muscle. J Biol Chem (1966) 1.04
Identification at strain level of Rhizoctonia solani AG4 isolates by direct sequence of asymmetric PCR products of the ITS regions. Curr Genet (1996) 1.04
Characterization of genomic structure and polymorphisms in the human carbamyl phosphate synthetase I gene. Gene (2003) 1.01
A kinetic and fluorimetric investigation of papain modified at tryptophan-69 and -177 by N-bromosuccinimide. Biochem J (1974) 1.01
Mechanism of the 2,3-diphosphoglycerate-dependent phosphoglycerate mutase from rabbit muscle. Biochem J (1972) 1.00
An international multicenter randomized study of computer-assisted oral anticoagulant dosage vs. medical staff dosage. J Thromb Haemost (2008) 1.00
ATPase activity of biotin carboxylase provides evidence for initial activation of HCO3- by ATP in the carboxylation of biotin. Arch Biochem Biophys (1986) 1.00
Stereochemistry of phosphoryl transfer. Philos Trans R Soc Lond B Biol Sci (1981) 1.00
The structure and mechanism of action of papain. Philos Trans R Soc Lond B Biol Sci (1970) 1.00
Biophysical properties of bacteriophage phi29. Virology (1974) 1.00
Steroid secretion by the adrenal gland of foetal and neonatal sheep. J Endocrinol (1968) 1.00
The stereochemical course of phosphoryl transfer catalysed by polynucleotide kinase (bacteriophage-T4-infected Escherichia coli B). Biochem J (1981) 0.99
Influence of ionic strength on apparent reaction mechanism of phosphoglycerate mutase. Biochemistry (1966) 0.99
Deacylation and transacetylation of acetyl glutamate and acetyl ornithine in rat liver. FEBS Lett (1977) 0.99
Kinetics and mechanism of action of muscle pyruvate kinase. Biochem J (1978) 0.99
Effect of 2,3-diphosphoglycerate on oxygen affinity of blood in sickle cell anemia. J Clin Invest (1970) 0.98
Carbamate kinase from Enterococcus faecalis and Enterococcus faecium--cloning of the genes, studies on the enzyme expressed in Escherichia coli, and sequence similarity with N-acetyl-L-glutamate kinase. Eur J Biochem (1998) 0.98
Carbamoyl phosphate synthetase, ornithine transcarbamylase, and aspartate transcarbamylase activities in the pea ovary : changes with senescence of the unpollinated ovary or with fruit set induced by gibberellic Acid. Plant Physiol (1989) 0.98
Carbamate kinase: New structural machinery for making carbamoyl phosphate, the common precursor of pyrimidines and arginine. Protein Sci (1999) 0.98
The concentrations of adrenocorticotrophin, vasopressin and oxytocin in the foetal and maternal plasma of the sheep in the latter half of gestation. J Endocrinol (1971) 0.97