Published in Nature on June 25, 1981
Linkage map of Escherichia coli K-12, edition 7. Microbiol Rev (1983) 30.35
Linkage map of Escherichia coli K-12, edition 10: the traditional map. Microbiol Mol Biol Rev (1998) 4.18
Structure of an Escherichia coli tRNA operon containing linked genes for arginine, histidine, leucine, and proline tRNAs. J Bacteriol (1984) 2.20
Histidine biosynthesis genes in Lactococcus lactis subsp. lactis. J Bacteriol (1992) 1.99
Essential nontranslational functions of tRNA synthetases. Nat Chem Biol (2013) 1.72
The eucaryotic aminoacyl-tRNA synthetase complex: suggestions for its structure and function. J Cell Biol (1984) 1.61
Crystal structure of a human aminoacyl-tRNA synthetase cytokine. Proc Natl Acad Sci U S A (2002) 1.40
Molecular cloning and regulation of expression of the genes for initiation factor 3 and two aminoacyl-tRNA synthetases. J Bacteriol (1982) 1.33
Comparative analysis of regulatory elements between Escherichia coli and Klebsiella pneumoniae by genome-wide transcription start site profiling. PLoS Genet (2012) 1.29
Posttranscriptional autoregulation of Escherichia coli threonyl tRNA synthetase expression in vivo. J Bacteriol (1986) 1.26
Functional expansion of human tRNA synthetases achieved by structural inventions. FEBS Lett (2010) 1.19
Aminoacyl-tRNA synthetase complexes: molecular multitasking revealed. FEMS Microbiol Rev (2008) 1.17
Crystal structure of tetrameric form of human lysyl-tRNA synthetase: Implications for multisynthetase complex formation. Proc Natl Acad Sci U S A (2008) 1.11
Multienzyme complex of aminoacyl-tRNA synthetases: an essence of being eukaryotic. Biochem J (1986) 0.92
Structure and transcription of the tRNAPro1 gene from Escherichia coli. Nucleic Acids Res (1985) 0.91
Escherichia coli phenylalanyl-tRNA synthetase operon: transcription studies of wild-type and mutated operons on multicopy plasmids. J Bacteriol (1982) 0.89
Regulation of angiogenesis by aminoacyl-tRNA synthetases. Int J Mol Sci (2014) 0.86
Regulation of tryptophanyl-tRNA synthetase formation. J Bacteriol (1982) 0.85
tRNA synthetase: tRNA aminoacylation and beyond. Wiley Interdiscip Rev RNA (2014) 0.84
Molecular cloning, sequence, structural analysis and expression of the histidyl-tRNA synthetase gene from Streptococcus equisimilis. Nucleic Acids Res (1993) 0.84
Structural similarities in the noncatalytic domains of phenylalanyl-tRNA and biotin synthetases. Protein Sci (1995) 0.83
Defective regulation of the phenylalanine biosynthetic operon in mutants of the phenylalanyl-tRNA synthetase operon. J Bacteriol (1987) 0.83
Two control systems modulate the level of glutaminyl-tRNA synthetase in Escherichia coli. J Bacteriol (1985) 0.82
Indolmycin-mediated inhibition and stimulation of transcription at the trp promoter of Escherichia coli. J Bacteriol (1983) 0.81
A biologically active 53 kDa fragment of overproduced alanyl-tRNA synthetase from Thermus thermophilus HB8 specifically interacts with tRNA Ala acceptor helix. Nucleic Acids Res (1997) 0.81
Adenylosuccinate lyase of Bacillus subtilis regulates the activity of the glutamyl-tRNA synthetase. Proc Natl Acad Sci U S A (1992) 0.80
Introduction of a leucine half-zipper engenders multiple high-quality crystals of a recalcitrant tRNA synthetase. Acta Crystallogr D Biol Crystallogr (2010) 0.79
Emergence and evolution. Top Curr Chem (2014) 0.78
Genomic analysis of the regulatory elements and links with intrinsic DNA structural properties in the shrunken genome of Buchnera. BMC Genomics (2013) 0.77
Urea Unfolding Study of E. coli Alanyl-tRNA Synthetase and Its Monomeric Variants Proves the Role of C-Terminal Domain in Stability. J Amino Acids (2015) 0.75
Studying nuclear functions of aminoacyl tRNA synthetases. Methods (2016) 0.75
Two crystal structures reveal design for repurposing the C-Ala domain of human AlaRS. Proc Natl Acad Sci U S A (2016) 0.75
Nucleotide sequence of yeast LEU2 shows 5'-noncoding region has sequences cognate to leucine. Cell (1982) 6.68
Principal neutralizing domain of the human immunodeficiency virus type 1 envelope protein. Proc Natl Acad Sci U S A (1989) 6.58
HTLV-III/LAV-neutralizing antibodies to an E. coli-produced fragment of the virus envelope. Science (1986) 6.33
Yeast LEU2. Repression of mRNA levels by leucine and primary structure of the gene product. J Biol Chem (1984) 5.84
A simple structural feature is a major determinant of the identity of a transfer RNA. Nature (1988) 5.11
Prevention of HIV-1 infection in chimpanzees by gp120 V3 domain-specific monoclonal antibody. Nature (1992) 4.75
Broadly neutralizing antibodies elicited by the hypervariable neutralizing determinant of HIV-1. Science (1990) 4.43
Deletion of an essential gene in Escherichia coli by site-specific recombination with linear DNA fragments. J Bacteriol (1984) 4.30
Two distinct cytokines released from a human aminoacyl-tRNA synthetase. Science (1999) 4.04
Enzyme structure with two catalytic sites for double-sieve selection of substrate. Science (1998) 3.92
Aminoacyl tRNA synthetases: general scheme of structure-function relationships in the polypeptides and recognition of transfer RNAs. Annu Rev Biochem (1987) 3.59
Aminoacylation of RNA minihelices with alanine. Nature (1989) 3.42
A formalin-inactivated whole SIV vaccine confers protection in macaques. Science (1989) 3.37
A DNA fragment with an alpha-phosphorothioate nucleotide at one end is asymmetrically blocked from digestion by exonuclease III and can be replicated in vivo. Proc Natl Acad Sci U S A (1981) 3.14
Antibody-mediated in vitro neutralization of human immunodeficiency virus type 1 abolishes infectivity for chimpanzees. J Virol (1990) 2.65
Epitopes recognized by the neutralizing antibodies of an HIV-1-infected individual. J Immunol (1990) 2.57
Specific sequence homology and three-dimensional structure of an aminoacyl transfer RNA synthetase. Science (1984) 2.52
Enlarging the amino acid set of Escherichia coli by infiltration of the valine coding pathway. Science (2001) 2.35
A single amino acid interchange yields reciprocal CTL specificities for HIV-1 gp160. Science (1989) 2.32
Type-restricted neutralization of molecular clones of human immunodeficiency virus. Science (1988) 2.31
Human monoclonal antibody that recognizes the V3 region of human immunodeficiency virus gp120 and neutralizes the human T-lymphotropic virus type IIIMN strain. Proc Natl Acad Sci U S A (1990) 2.29
Helper T-cell antigenic site identification in the acquired immunodeficiency syndrome virus gp120 envelope protein and induction of immunity in mice to the native protein using a 16-residue synthetic peptide. Proc Natl Acad Sci U S A (1987) 2.25
Modular arrangement of functional domains along the sequence of an aminoacyl tRNA synthetase. Nature (1984) 2.04
Two nuclear factors compete for the skeletal muscle actin promoter. J Biol Chem (1987) 2.02
Yeast LEU1. Repression of mRNA levels by leucine and relationship of 5'-noncoding region to that of LEU2. J Biol Chem (1984) 2.01
Specificity for aminoacylation of an RNA helix: an unpaired, exocyclic amino group in the minor groove. Science (1991) 1.96
Mutations in the principal neutralization determinant of human immunodeficiency virus type 1 affect syncytium formation, virus infectivity, growth kinetics, and neutralization. J Virol (1992) 1.94
Aminoacylation error correction. Nature (1996) 1.93
Primary structure of a large aminoacyl-tRNA synthetase. Science (1981) 1.93
Evidence for dispensable sequences inserted into a nucleotide fold. Science (1987) 1.85
Detection of leucine-independent DNA site occupancy of the yeast Leu3p transcriptional activator in vivo. Mol Cell Biol (1995) 1.79
LEU3 of Saccharomyces cerevisiae encodes a factor for control of RNA levels of a group of leucine-specific genes. Mol Cell Biol (1987) 1.79
Mutational isolation of a sieve for editing in a transfer RNA synthetase. Science (1994) 1.76
LEU3 of Saccharomyces cerevisiae activates multiple genes for branched-chain amino acid biosynthesis by binding to a common decanucleotide core sequence. Mol Cell Biol (1988) 1.72
Functional assembly of a randomly cleaved protein. Proc Natl Acad Sci U S A (1992) 1.65
Understanding structural relationships in proteins of unsolved three-dimensional structure. Proteins (1990) 1.65
A covalent adduct between the uracil ring and the active site of an aminoacyl tRNA synthetase. Nature (1982) 1.65
Overlapping nucleotide determinants for specific aminoacylation of RNA microhelices. Science (1992) 1.64
Enzymatic aminoacylation of an eight-base-pair microhelix with histidine. Proc Natl Acad Sci U S A (1990) 1.63
Structural relationships and the classification of aminoacyl-tRNA synthetases. J Biol Chem (1991) 1.61
Gene for yeast glutamine tRNA synthetase encodes a large amino-terminal extension and provides a strong confirmation of the signature sequence for a group of the aminoacyl-tRNA synthetases. J Biol Chem (1987) 1.59
Aminoacyl-tRNA synthetases: potential markers of genetic code development. Trends Biochem Sci (2001) 1.58
Two classes of tRNA synthetases suggested by sterically compatible dockings on tRNA acceptor stem. Cell (2001) 1.57
Primary structure of histidine-tRNA synthetase and characterization of hisS transcripts. J Biol Chem (1985) 1.53
Functional contacts of a transfer RNA synthetase with 2'-hydroxyl groups in the RNA minor groove. Nature (1992) 1.52
A new troponin T and cDNA clones for 13 different muscle proteins, found by shotgun sequencing. Nature (1983) 1.49
Transfer RNA-dependent translocation of misactivated amino acids to prevent errors in protein synthesis. Mol Cell (1999) 1.48
DNA-binding site for two skeletal actin promoter factors is important for expression in muscle cells. Mol Cell Biol (1988) 1.47
Enzymatic aminoacylation of single-stranded RNA with an RNA cofactor. Proc Natl Acad Sci U S A (1991) 1.46
Sequence determination and modeling of structural motifs for the smallest monomeric aminoacyl-tRNA synthetase. Proc Natl Acad Sci U S A (1991) 1.46
Construction of peptides encompassing multideterminant clusters of human immunodeficiency virus envelope to induce in vitro T cell responses in mice and humans of multiple MHC types. J Clin Invest (1991) 1.44
Highly differentiated motifs responsible for two cytokine activities of a split human tRNA synthetase. J Biol Chem (1999) 1.40
Discrete determinants in transfer RNA for editing and aminoacylation. Science (1997) 1.39
Artificially ambiguous genetic code confers growth yield advantage. Proc Natl Acad Sci U S A (2004) 1.36
Enzymatic aminoacylation of sequence-specific RNA minihelices and hybrid duplexes with methionine. Proc Natl Acad Sci U S A (1992) 1.35
Structural requirements for class I MHC molecule-mediated antigen presentation and cytotoxic T cell recognition of an immunodominant determinant of the human immunodeficiency virus envelope protein. J Exp Med (1989) 1.35
Human glycyl-tRNA synthetase. Wide divergence of primary structure from bacterial counterpart and species-specific aminoacylation. J Biol Chem (1994) 1.34
Genetic code in evolution: switching species-specific aminoacylation with a peptide transplant. EMBO J (1998) 1.32
Primary structures of both subunits of Escherichia coli glycyl-tRNA synthetase. J Biol Chem (1983) 1.32
The complete nucleotide sequence for rabbit muscle aldolase A messenger RNA. J Biol Chem (1984) 1.30
Evidence for interaction of an aminoacyl transfer RNA synthetase with a region important for the identity of its cognate transfer RNA. J Biol Chem (1988) 1.29
A bacterial amber suppressor in Saccharomyces cerevisiae is selectively recognized by a bacterial aminoacyl-tRNA synthetase. Mol Cell Biol (1990) 1.29
Dispensable pieces of an aminoacyl tRNA synthetase which activate the catalytic site. Cell (1984) 1.28
Residues in a class I tRNA synthetase which determine selectivity of amino acid recognition in the context of tRNA. Biochemistry (1995) 1.26
A nucleotide that enhances the charging of RNA minihelix sequence variants with alanine. Biochemistry (1990) 1.26
A month-long effect from a single injection of microencapsulated human growth hormone. Nat Med (1996) 1.24
A single base pair affects binding and catalytic parameters in the molecular recognition of a transfer RNA. Biochemistry (1989) 1.24
Evidence that a major determinant for the identity of a transfer RNA is conserved in evolution. Biochemistry (1989) 1.24
Assembly of a class I tRNA synthetase from products of an artificially split gene. Biochemistry (1991) 1.23
Aminoacylation of alanine minihelices. "Discriminator" base modulates transition state of single turnover reaction. J Biol Chem (1991) 1.22
Species barrier to RNA recognition overcome with nonspecific RNA binding domains. J Biol Chem (1999) 1.22
Human lysyl-tRNA synthetase accepts nucleotide 73 variants and rescues Escherichia coli double-defective mutant. J Biol Chem (1997) 1.21
Errors from selective disruption of the editing center in a tRNA synthetase. Biochemistry (2000) 1.21
Reversal of creatine kinase translational repression by 3' untranslated sequences. Science (1990) 1.21
Maintaining genetic code through adaptations of tRNA synthetases to taxonomic domains. Trends Biochem Sci (1997) 1.20
Genetic code origins: tRNAs older than their synthetases? Proc Natl Acad Sci U S A (1998) 1.18
Purification and properties of alanine tRNA synthetase from Escherichia coli A tetramer of identical subunits. J Biol Chem (1981) 1.16
The novel fragment of tyrosyl tRNA synthetase, mini-TyrRS, is secreted to induce an angiogenic response in endothelial cells. FASEB J (2007) 1.14
Domain-domain communication in aminoacyl-tRNA synthetases. Prog Nucleic Acid Res Mol Biol (2001) 1.14
Gene for Escherichia coli glycyl-tRNA synthetase has tandem subunit coding regions in the same reading frame. J Biol Chem (1982) 1.14
Modeling with in vitro kinetic parameters for the elaboration of transfer RNA identity in vivo. Biochemistry (1989) 1.13
Dissection of a class II tRNA synthetase: determinants for minihelix recognition are tightly associated with domain for amino acid activation. Biochemistry (1993) 1.12
Evidence from cassette mutagenesis for a structure-function motif in a protein of unknown structure. Science (1988) 1.12
Induction of a cellular enzyme for energy metabolism by transforming domains of adenovirus E1a. Mol Cell Biol (1990) 1.11
Rescuing an essential enzyme-RNA complex with a non-essential appended domain. EMBO J (1997) 1.10
A large internal deletion converts yeast LEU3 to a constitutive transcriptional activator. Mol Cell Biol (1989) 1.10
Evidence for a unique first position codon-anticodon mismatch in vivo. J Mol Biol (1988) 1.09
Cloning, partial sequencing, and in vitro transcription of the gene for alanine tRNA synthetase. J Biol Chem (1981) 1.08
Functional analysis of peptide motif for RNA microhelix binding suggests new family of RNA-binding domains. EMBO J (1998) 1.08
A view into the origin of life: aminoacyl-tRNA synthetases. Cell Mol Life Sci (2000) 1.08
Major anticodon-binding region missing from an archaebacterial tRNA synthetase. J Biol Chem (1999) 1.08
Species-specific tRNA recognition in relation to tRNA synthetase contact residues. J Mol Biol (1997) 1.08
Biologically active fragment of a human tRNA synthetase inhibits fluid shear stress-activated responses of endothelial cells. Proc Natl Acad Sci U S A (2003) 1.07
Protein synthesis editing by a DNA aptamer. Proc Natl Acad Sci U S A (1996) 1.06
Internal structural features of E. coli glycyl-tRNA synthetase examined by subunit polypeptide chain fusions. J Biol Chem (1986) 1.06
Structure-specific tRNA-binding protein from the extreme thermophile Aquifex aeolicus. EMBO J (1999) 1.06
RNA binding determinant in some class I tRNA synthetases identified by alignment-guided mutagenesis. Proc Natl Acad Sci U S A (1992) 1.04
Human immunodeficiency virus type 1 entry into T cells: more-rapid escape from an anti-V3 loop than from an antireceptor antibody. J Virol (1992) 1.04